Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated β-cell death

Diabetes

Volumn 59, Issue 2, 2010, Pages 440-447

  Chen, Junqin ^a   Fontes, Ghislaine ^b   Saxena, Geetu ^a   Poitout, Vincent ^b   Shalev, Anath ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; FATTY ACID; GLUCOSE; PALMITIC ACID; STAUROSPORINE; THAPSIGARGIN; THIOREDOXIN INTERACTING PROTEIN; CARRIER PROTEIN; PRIMER DNA; THIOREDOXIN; TXNIP PROTEIN, MOUSE; TXNIP PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; IMMUNOBLOTTING; MALE; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; C3H MOUSE; CELL CULTURE; CELL DEATH; CELL SEPARATION; CYTOLOGY; DRUG EFFECT; GENETICS; MITOCHONDRION; MOUSE MUTANT; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOP CODON; WISTAR RAT;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL DEATH; CELL SEPARATION; CELLS, CULTURED; CODON, NONSENSE; DIABETES MELLITUS; DNA PRIMERS; FATTY ACIDS; GLUCOSE; IN SITU NICK-END LABELING; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MITOCHONDRIA; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOREDOXINS;

EID: 77449151150     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0949     Document Type: Article

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