Increased interleukin (IL)-1β messenger ribonucleic acid expression in β-cells of individuals with type 2 diabetes and regulation of IL-1β in human islets by glucose and autostimulation

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 10, 2008, Pages 4065-4074

  Böni Schnetzler, Marianne ^a   Thorne, Jeffrey ^b   Parnaud, Géraldine ^c   Marselli, Lorella ^b   Ehses, Jan A ^a   Kerr Conte, Julie ^d   Pattou, Francois ^d   Halban, Philippe A ^c   Weir, Gordon C ^b   Donath, Marc Y ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA;

ARTICLE; CELL CULTURE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTER; GENE CONTROL; HUMAN; HUMAN CELL; LASER CAPTURE MICRODISSECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

AUTOCRINE COMMUNICATION; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION PROFILING; GLUCOSE; HUMANS; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; ISLETS OF LANGERHANS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; UP-REGULATION;

EID: 53749100698     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-0396     Document Type: Article

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