메뉴 건너뛰기




Volumn 77, Issue 5, 2005, Pages 587-597

Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: Implications for intrahepatic grafts

Author keywords

Cytokines; Ischemia reperfusion; Kupffer cell; Portal vein

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; L SELECTIN; NITRIC OXIDE;

EID: 18244364592     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1104649     Document Type: Review
Times cited : (267)

References (149)
  • 1
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro, A. M., Lakey, J. R., Ryan, E. A., Korbutt, G. S., Toth, E., Warnock, G. L., Kneteman, N. M., Rajotte, R. V. (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343, 230-238.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 3
    • 0742269907 scopus 로고    scopus 로고
    • Insulin independence achieved using the transmesenteric approach to the portal vein for islet transplantation
    • Osama, G. A., Chamsuddin, A., Fraga, D., Fisher, J., Lo, A. (2004) Insulin independence achieved using the transmesenteric approach to the portal vein for islet transplantation. Transplantation 77, 309-311.
    • (2004) Transplantation , vol.77 , pp. 309-311
    • Osama, G.A.1    Chamsuddin, A.2    Fraga, D.3    Fisher, J.4    Lo, A.5
  • 4
    • 0015386234 scopus 로고
    • Transplantation of intact pancreatic islets in rats
    • Ballinger, W. F., Lacy, P. E. (1972) Transplantation of intact pancreatic islets in rats. Surgery 72, 175-186.
    • (1972) Surgery , vol.72 , pp. 175-186
    • Ballinger, W.F.1    Lacy, P.E.2
  • 6
    • 0037184814 scopus 로고    scopus 로고
    • Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center
    • Goss, J. A., Schock, A. P., Brunicardi, F. C., Goodpastor, S. E., Garber, A. J., Soltes, G., Barth, M., Froud, T., Alejandro, R., Ricordi, C. (2002) Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center. Transplantation 74, 1761-1766.
    • (2002) Transplantation , vol.74 , pp. 1761-1766
    • Goss, J.A.1    Schock, A.P.2    Brunicardi, F.C.3    Goodpastor, S.E.4    Garber, A.J.5    Soltes, G.6    Barth, M.7    Froud, T.8    Alejandro, R.9    Ricordi, C.10
  • 8
    • 0028279898 scopus 로고
    • Protection of mouse islet isografts from early transplantation damage by nicotinamide treatment of recipients
    • Kenmochi, T., Mullen, Y., Miyamoto, M., Stein, E. (1994) Protection of mouse islet isografts from early transplantation damage by nicotinamide treatment of recipients. Transplant. Proc. 26, 693.
    • (1994) Transplant. Proc. , vol.26 , pp. 693
    • Kenmochi, T.1    Mullen, Y.2    Miyamoto, M.3    Stein, E.4
  • 9
    • 0031890972 scopus 로고    scopus 로고
    • Transplantation of allogeneic islets of Langerhans in the rat liver: Effects of macrophage depletion on graft survival and microenvironment activation
    • Bottino, R., Fernandez, L. A., Ricordi, C., Lehmann, R., Tsan, M. F., Oliver, R., Inverardi, L. (1998) Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation. Diabetes 47, 316-323.
    • (1998) Diabetes , vol.47 , pp. 316-323
    • Bottino, R.1    Fernandez, L.A.2    Ricordi, C.3    Lehmann, R.4    Tsan, M.F.5    Oliver, R.6    Inverardi, L.7
  • 13
    • 0036097472 scopus 로고    scopus 로고
    • β-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia
    • Biarnes, M., Montolio, M., Nacher, V., Raurell, M., Soler, J., Montanya, E. (2002) β-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 51, 66-72.
    • (2002) Diabetes , vol.51 , pp. 66-72
    • Biarnes, M.1    Montolio, M.2    Nacher, V.3    Raurell, M.4    Soler, J.5    Montanya, E.6
  • 14
    • 0025279590 scopus 로고
    • Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts
    • Kaufman, D. B., Platt, J. L., Rabe, F. L., Dunn, D. L., Bach, F. H., Sutherland, D. E. (1990) Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts. J. Exp. Med. 172, 291-302.
    • (1990) J. Exp. Med. , vol.172 , pp. 291-302
    • Kaufman, D.B.1    Platt, J.L.2    Rabe, F.L.3    Dunn, D.L.4    Bach, F.H.5    Sutherland, D.E.6
  • 15
    • 0028225856 scopus 로고
    • Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass
    • Kaufman, D. B., Gores, P. F., Field, M. J., Farney, A. C., Gruber, S. A., Stephanian, E., Sutherland, D. E. (1994) Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass. Diabetes 43, 778-783.
    • (1994) Diabetes , vol.43 , pp. 778-783
    • Kaufman, D.B.1    Gores, P.F.2    Field, M.J.3    Farney, A.C.4    Gruber, S.A.5    Stephanian, E.6    Sutherland, D.E.7
  • 16
    • 0036014899 scopus 로고    scopus 로고
    • Inhibition of interleukin-1β-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet β-cell function
    • Tran, P. O., Gleason, C. E., Robertson, R. P. (2002) Inhibition of interleukin-1β-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet β-cell function. Diabetes 51, 1772-1778.
    • (2002) Diabetes , vol.51 , pp. 1772-1778
    • Tran, P.O.1    Gleason, C.E.2    Robertson, R.P.3
  • 18
    • 0035128723 scopus 로고    scopus 로고
    • β-cell apoptosis: Stimuli and signaling
    • Mandrup-Poulsen, T. (2001) β-cell apoptosis: stimuli and signaling. Diabetes 50 (Suppl. 1), S58-S63.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Mandrup-Poulsen, T.1
  • 21
    • 0029817047 scopus 로고    scopus 로고
    • The role of interleukin-1 in the pathogenesis of IDDM
    • Mandrup-Poulsen, T. (1996) The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 39, 1005-1029.
    • (1996) Diabetologia , vol.39 , pp. 1005-1029
    • Mandrup-Poulsen, T.1
  • 23
    • 0033615530 scopus 로고    scopus 로고
    • Prostaglandin E(2) mediates inhibition of insulin secretion by interleukin-1β
    • Tran, P. O., Gleason, C. E., Poitout, V., Robertson, R. P. (1999) Prostaglandin E(2) mediates inhibition of insulin secretion by interleukin-1β. J. Biol. Chem. 274, 31245-31248.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31245-31248
    • Tran, P.O.1    Gleason, C.E.2    Poitout, V.3    Robertson, R.P.4
  • 24
    • 0027232067 scopus 로고
    • NF-κ B and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli, M., Chiu, J. J., Lenardo, M. J. (1993) NF-κ B and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143, 1-62.
    • (1993) Int. Rev. Cytol. , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 25
    • 0023147156 scopus 로고
    • Secretory products of macrophages
    • Nathan, C. F. (1987) Secretory products of macrophages. J. Clin. Invest. 79, 319-326.
    • (1987) J. Clin. Invest. , vol.79 , pp. 319-326
    • Nathan, C.F.1
  • 27
    • 0028271718 scopus 로고
    • The role of nitric oxide in IL-1 β-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts
    • Xenos, E. S., Stevens, R. B., Sutherland, D. E., Lokeh, A., Ansite, J. D., Casanova, D., Gores, P. F., Platt, J. L. (1994) The role of nitric oxide in IL-1 β-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts. Transplantation 57, 1208-1212.
    • (1994) Transplantation , vol.57 , pp. 1208-1212
    • Xenos, E.S.1    Stevens, R.B.2    Sutherland, D.E.3    Lokeh, A.4    Ansite, J.D.5    Casanova, D.6    Gores, P.F.7    Platt, J.L.8
  • 29
    • 0030827057 scopus 로고    scopus 로고
    • Tumour necrosis factor α and interleukin 1 signalling: Do MAPKK kinases connect it all?
    • Eder, J. (1997) Tumour necrosis factor α and interleukin 1 signalling: do MAPKK kinases connect it all? Trends Pharmacol. Sci. 18, 319-322.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 319-322
    • Eder, J.1
  • 30
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin-1
    • Cao, Z., Xiong, J., Takeuchi, M., Kurama, T., Goeddel, D. V. (1996) TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 31
    • 0031899972 scopus 로고    scopus 로고
    • Evidence for involvement of the proteasome complex (26S) and NFκB in IL-1β-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells
    • Kwon, G., Corbett, J. A., Hauser, S., Hill, J. R., Turk, J., McDaniel, M. L. (1998) Evidence for involvement of the proteasome complex (26S) and NFκB in IL-1β-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells. Diabetes 47, 583-591.
    • (1998) Diabetes , vol.47 , pp. 583-591
    • Kwon, G.1    Corbett, J.A.2    Hauser, S.3    Hill, J.R.4    Turk, J.5    McDaniel, M.L.6
  • 32
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-κ B1 precursor protein and the activation of NF-κ B
    • Palombella, V. J., Rando, O. J., Goldberg, A. L., Maniatis, T. (1994) The ubiquitin-proteasome pathway is required for processing the NF-κ B1 precursor protein and the activation of NF-κ B. Cell 78, 773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 33
    • 0028167846 scopus 로고
    • Inhibition of NF-κ B by sodium salicylate and aspirin
    • Kopp, E., Ghosh, S. (1994) Inhibition of NF-κ B by sodium salicylate and aspirin. Science 265, 956-959.
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 34
    • 0025911970 scopus 로고
    • Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene
    • Degitz, K., Li, L. J., Caughman, S. W. (1991) Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. J. Biol. Chem. 266, 14024-14030.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14024-14030
    • Degitz, K.1    Li, L.J.2    Caughman, S.W.3
  • 35
    • 0037603320 scopus 로고    scopus 로고
    • IL-1β, IFN-γ and TNF-α increase vulnerability of pancreatic β cells to autoimmune destruction
    • Wachlin, G., Augstein, P., Schroder, D., Kuttler, B., Kloting, I., Heinke, P., Schmidt, S. (2003) IL-1β, IFN-γ and TNF-α increase vulnerability of pancreatic β cells to autoimmune destruction. J. Autoimmun. 20, 303-312.
    • (2003) J. Autoimmun. , vol.20 , pp. 303-312
    • Wachlin, G.1    Augstein, P.2    Schroder, D.3    Kuttler, B.4    Kloting, I.5    Heinke, P.6    Schmidt, S.7
  • 36
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide
    • Xie, Q. W., Whisnant, R., Nathan, C. (1993) Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide. J. Exp. Med. 177, 1779-1784.
    • (1993) J. Exp. Med. , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 37
    • 0027976653 scopus 로고
    • The cytoplasmic domain of the interleukin-1 receptor is required for nuclear factor-κ B signal transduction
    • Leung, K., Betts, J. C., Xu, L., Nabel, G. J. (1994) The cytoplasmic domain of the interleukin-1 receptor is required for nuclear factor-κ B signal transduction. J. Biol. Chem. 269, 1579-1582.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1579-1582
    • Leung, K.1    Betts, J.C.2    Xu, L.3    Nabel, G.J.4
  • 38
    • 0033557102 scopus 로고    scopus 로고
    • Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase
    • Park, C., Kim, J. R., Shim, J. K., Kang, B. S., Park, Y. G., Nam, K. S., Lee, Y. C., Kim, C. H. (1999) Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase. Arch. Biochem. Biouhys. 362, 217-224.
    • (1999) Arch. Biochem. Biouhys. , vol.362 , pp. 217-224
    • Park, C.1    Kim, J.R.2    Shim, J.K.3    Kang, B.S.4    Park, Y.G.5    Nam, K.S.6    Lee, Y.C.7    Kim, C.H.8
  • 39
    • 0025736821 scopus 로고
    • Diabetic hyperglycemia: Link to impaired glucose transport in pancreatic β cells
    • Unger, R. H. (1991) Diabetic hyperglycemia: link to impaired glucose transport in pancreatic β cells. Science 251, 1200-1205.
    • (1991) Science , vol.251 , pp. 1200-1205
    • Unger, R.H.1
  • 40
    • 0030923812 scopus 로고    scopus 로고
    • Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells
    • Delaney, C. A., Pavlovic, D., Hoorens, A., Pipeleers, D. G., Eizirik, D. L. (1997) Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 138, 2610-2614.
    • (1997) Endocrinology , vol.138 , pp. 2610-2614
    • Delaney, C.A.1    Pavlovic, D.2    Hoorens, A.3    Pipeleers, D.G.4    Eizirik, D.L.5
  • 42
    • 0030995686 scopus 로고    scopus 로고
    • Treatment with neutralizing antibodies specific for IL-1β prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
    • Cailleau, C., Diu-Hercend, A., Ruuth, E., Westwood, R., Carnaud, C. (1997) Treatment with neutralizing antibodies specific for IL-1β prevents cyclophosphamide-induced diabetes in nonobese diabetic mice. Diabetes 46, 937-940.
    • (1997) Diabetes , vol.46 , pp. 937-940
    • Cailleau, C.1    Diu-Hercend, A.2    Ruuth, E.3    Westwood, R.4    Carnaud, C.5
  • 45
    • 0034036353 scopus 로고    scopus 로고
    • Synergistic activation of NF-κab and inducible isoform of nitric oxide synthase induction by interferon-γ and tumor necrosis factor-α in INS-1 cells
    • Sekine, N., Ishikawa, T., Okazaki, T., Hayashi, M., Wollheim, C. B., Fujita, T. (2000) Synergistic activation of NF-κab and inducible isoform of nitric oxide synthase induction by interferon-γ and tumor necrosis factor-α in INS-1 cells. J. Cell. Physiol. 184, 46-57.
    • (2000) J. Cell. Physiol. , vol.184 , pp. 46-57
    • Sekine, N.1    Ishikawa, T.2    Okazaki, T.3    Hayashi, M.4    Wollheim, C.B.5    Fujita, T.6
  • 46
    • 0038142707 scopus 로고    scopus 로고
    • Nuclear factor κB protects pancreatic β-cells from tumor necrosis factor-α-mediated apoptosis
    • Chang, I., Kim, S., Kim, J. Y., Cho, N., Kim, Y. H., Kim, H. S., Lee, M. K., Kim, K. W., Lee, M. S. (2003) Nuclear factor κB protects pancreatic β-cells from tumor necrosis factor-α-mediated apoptosis. Diabetes 52, 1169-1175.
    • (2003) Diabetes , vol.52 , pp. 1169-1175
    • Chang, I.1    Kim, S.2    Kim, J.Y.3    Cho, N.4    Kim, Y.H.5    Kim, H.S.6    Lee, M.K.7    Kim, K.W.8    Lee, M.S.9
  • 47
    • 0033305236 scopus 로고    scopus 로고
    • Tumor necrosis factor-α-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic β cells
    • Stephens, L. A., Thomas, H. E., Ming, L., Grell, M., Darwiche, R., Volodin, L., Kay, T. W. (1999) Tumor necrosis factor-α-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic β cells. Endocrinology 140, 3219-3227.
    • (1999) Endocrinology , vol.140 , pp. 3219-3227
    • Stephens, L.A.1    Thomas, H.E.2    Ming, L.3    Grell, M.4    Darwiche, R.5    Volodin, L.6    Kay, T.W.7
  • 49
    • 0024421432 scopus 로고
    • Interaction of β-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans
    • Palmer, J. P., Helqvist, S., Spinas, G. A., Molvig, J., Mandrup-Poulsen, T., Andersen, H. U., Nerup, J. (1989) Interaction of β-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans. Diabetes 38, 1211-1216.
    • (1989) Diabetes , vol.38 , pp. 1211-1216
    • Palmer, J.P.1    Helqvist, S.2    Spinas, G.A.3    Molvig, J.4    Mandrup-Poulsen, T.5    Andersen, H.U.6    Nerup, J.7
  • 50
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase
    • Corbett, J. A., McDaniel, M. L. (1995) Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase. J. Exp. Med. 181, 559-568.
    • (1995) J. Exp. Med. , vol.181 , pp. 559-568
    • Corbett, J.A.1    McDaniel, M.L.2
  • 51
    • 0025685395 scopus 로고
    • Inhibition of insulin secretion by interleukin-1 β and tumor necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism
    • Southern, C., Schulster, D., Green, I. C. (1990) Inhibition of insulin secretion by interleukin-1 β and tumor necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett. 276, 42-44.
    • (1990) FEBS Lett. , vol.276 , pp. 42-44
    • Southern, C.1    Schulster, D.2    Green, I.C.3
  • 52
    • 0025833992 scopus 로고
    • Interleukin-1 β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
    • Welsh, N., Eizirik, D. L., Bendtzen, K., Sandler, S. (1991) Interleukin-1 β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology 129, 3167-3173.
    • (1991) Endocrinology , vol.129 , pp. 3167-3173
    • Welsh, N.1    Eizirik, D.L.2    Bendtzen, K.3    Sandler, S.4
  • 53
    • 0027428461 scopus 로고
    • Endogenous nitric oxide induced by interleukin-1 β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
    • Delaney, C. A., Green, M. H., Lowe, J. E., Green, I. C. (1993) Endogenous nitric oxide induced by interleukin-1 β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Lett. 333, 291-295.
    • (1993) FEBS Lett. , vol.333 , pp. 291-295
    • Delaney, C.A.1    Green, M.H.2    Lowe, J.E.3    Green, I.C.4
  • 54
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller, H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 55
    • 0028035106 scopus 로고
    • The high-output nitric oxide pathway: Role and regulation
    • Xie, Q., Nathan, C. (1994) The high-output nitric oxide pathway: role and regulation. J. Leukoc. Biol. 56, 576-582.
    • (1994) J. Leukoc. Biol. , vol.56 , pp. 576-582
    • Xie, Q.1    Nathan, C.2
  • 56
    • 0028345247 scopus 로고
    • Role of nitric oxide in the pathogenesis of early pancreatic islet dysfunction during rat and human intraportal islet transplantation
    • Stevens, R. B., Lokeh, A., Ansite, J. D., Field, M. J., Gores, P. F., Sutherland, D. E. (1994) Role of nitric oxide in the pathogenesis of early pancreatic islet dysfunction during rat and human intraportal islet transplantation. Transplant. Proc. 26, 692.
    • (1994) Transplant. Proc. , vol.26 , pp. 692
    • Stevens, R.B.1    Lokeh, A.2    Ansite, J.D.3    Field, M.J.4    Gores, P.F.5    Sutherland, D.E.6
  • 57
    • 0030049390 scopus 로고    scopus 로고
    • Prostaglandin synthase 2
    • Herschman, H. R. (1996) Prostaglandin synthase 2. Biochim. Biophys. Acta 1299, 125-140.
    • (1996) Biochim. Biophys. Acta , vol.1299 , pp. 125-140
    • Herschman, H.R.1
  • 58
    • 0032539608 scopus 로고    scopus 로고
    • Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet
    • Sorli, C. H., Zhang, H. J., Armstrong, M. B., Rajotte, R. V., Maclouf, J., Robertson, R. P. (1998) Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet. Proc. Natl. Acad. Sci. USA 95, 1788-1793.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1788-1793
    • Sorli, C.H.1    Zhang, H.J.2    Armstrong, M.B.3    Rajotte, R.V.4    Maclouf, J.5    Robertson, R.P.6
  • 59
    • 0027162479 scopus 로고
    • Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog
    • Xie, W., Merrill, J. R., Bradshaw, W. S., Simmons, D. L. (1993) Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog. Arch. Biochem. Biophys. 300, 247-252.
    • (1993) Arch. Biochem. Biophys. , vol.300 , pp. 247-252
    • Xie, W.1    Merrill, J.R.2    Bradshaw, W.S.3    Simmons, D.L.4
  • 60
    • 0017666914 scopus 로고
    • A role for prostaglandin E in defective insulin secretion and carbohydrate intolerance in diabetes mellitus
    • Robertson, R. P., Chen, M. (1977) A role for prostaglandin E in defective insulin secretion and carbohydrate intolerance in diabetes mellitus. J. Clin. Invest. 60, 747-753.
    • (1977) J. Clin. Invest. , vol.60 , pp. 747-753
    • Robertson, R.P.1    Chen, M.2
  • 61
    • 0029910349 scopus 로고    scopus 로고
    • Prostanoid receptors of murine NIH 3T3 and RAW 264.7 cells. Structure and expression of the murine prostaglandin EP4 receptor gene
    • Arakawa, T., Laneuville, O., Miller, C. A., Lakkides, K. M., Wingerd, B. A., DeWitt, D. L., Smith, W. L. (1996) Prostanoid receptors of murine NIH 3T3 and RAW 264.7 cells. Structure and expression of the murine prostaglandin EP4 receptor gene. J. Biol. Chem. 271, 29569-29575.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29569-29575
    • Arakawa, T.1    Laneuville, O.2    Miller, C.A.3    Lakkides, K.M.4    Wingerd, B.A.5    DeWitt, D.L.6    Smith, W.L.7
  • 62
    • 0034956087 scopus 로고    scopus 로고
    • Increased islet viability by addition of beraprost sodium to collagenase solution
    • Arita, S., Une, S., Ohtsuka, S., Kawahara, T., Kasraie, A., Smith, C. V., Mullen, Y. (2001) Increased islet viability by addition of beraprost sodium to collagenase solution. Pancreas 23, 62-67.
    • (2001) Pancreas , vol.23 , pp. 62-67
    • Arita, S.1    Une, S.2    Ohtsuka, S.3    Kawahara, T.4    Kasraie, A.5    Smith, C.V.6    Mullen, Y.7
  • 63
  • 64
    • 0022527933 scopus 로고
    • Xanthine oxidase: A critical mediator of myocardial injury during ischemia and reperfusion?
    • Hearse, D. J., Manning, A. S., Downey, J. M., Yellon, D. M. (1986) Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion? Acta Physiol. Scand. Suppl. 548, 65-78.
    • (1986) Acta Physiol. Scand. Suppl. , vol.548 , pp. 65-78
    • Hearse, D.J.1    Manning, A.S.2    Downey, J.M.3    Yellon, D.M.4
  • 65
    • 0023925294 scopus 로고
    • Free radicals in medicine. I. Chemical nature and biologic reactions
    • Southorn, P. A., Powis, G. (1988) Free radicals in medicine. I. Chemical nature and biologic reactions. Mayo Clin. Proc. 63, 381-389.
    • (1988) Mayo Clin. Proc. , vol.63 , pp. 381-389
    • Southorn, P.A.1    Powis, G.2
  • 66
    • 18244387880 scopus 로고
    • Ischemia-reperfusion injury in pancreas organ transplantation
    • (B. A. Zikria, M. O. Oz, eds.), Armonk, NY, Futura
    • Ar'Rajab, A., Dawidson, I. (1994) Ischemia-reperfusion injury in pancreas organ transplantation. In Reperfusion Injury and Clinical Capillary Leak Syndrome (B. A. Zikria, M. O. Oz, eds.), Armonk, NY, Futura, 341-354.
    • (1994) Reperfusion Injury and Clinical Capillary Leak Syndrome , pp. 341-354
    • Ar'Rajab, A.1    Dawidson, I.2
  • 68
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
    • Lenzen, S., Drinkgern, J., Tiedge, M. (1996) Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic. Biol. Med. 20, 463-466.
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 463-466
    • Lenzen, S.1    Drinkgern, J.2    Tiedge, M.3
  • 69
    • 0032547768 scopus 로고    scopus 로고
    • Pancreatic β cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
    • Hotta, M., Tashiro, F., Ikegami, H., Niwa, H., Ogihara, T., Yodoi, J., Miyazaki, J. (1998) Pancreatic β cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes. J. Exp. Med. 188, 1445-1451.
    • (1998) J. Exp. Med. , vol.188 , pp. 1445-1451
    • Hotta, M.1    Tashiro, F.2    Ikegami, H.3    Niwa, H.4    Ogihara, T.5    Yodoi, J.6    Miyazaki, J.7
  • 71
    • 0032080663 scopus 로고    scopus 로고
    • Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1β- induced cytotoxicity and reduces nitric oxide production
    • Hohmeier, H. E., Thigpen, A., Tran, V. V., Davis, R., Newgard, C. B. (1998) Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1β- induced cytotoxicity and reduces nitric oxide production. J. Clin. Invest. 101, 1811-1820.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1811-1820
    • Hohmeier, H.E.1    Thigpen, A.2    Tran, V.V.3    Davis, R.4    Newgard, C.B.5
  • 74
    • 77049131103 scopus 로고
    • Quantitative study of the granulopectic activity of the reticulo-endothelial system. II. A study of the kinetics of the R. E. S. in relation to the dose of carbon injected; relationship between the weight of the organs and their activity
    • Biozzi, G., Benacerraf, B., Halpern, B. (1953) Quantitative study of the granulopectic activity of the reticulo-endothelial system. II. A study of the kinetics of the R. E. S. in relation to the dose of carbon injected; relationship between the weight of the organs and their activity. Br. J. Exp. Pathol. 34, 441-457.
    • (1953) Br. J. Exp. Pathol. , vol.34 , pp. 441-457
    • Biozzi, G.1    Benacerraf, B.2    Halpern, B.3
  • 75
    • 0025051058 scopus 로고
    • Biologically active products of stimulated liver macrophages (Kupffer cells)
    • Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192, 245-261.
    • (1990) Eur. J. Biochem. , vol.192 , pp. 245-261
    • Decker, K.1
  • 76
    • 0024573303 scopus 로고
    • An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro
    • Billiar, T. R., Curran, R. D., Stuehr, D. J., West, M. A., Bentz, B. G., Simmons, R. L. (1989) An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J. Exp. Med. 169, 1467-1472.
    • (1989) J. Exp. Med. , vol.169 , pp. 1467-1472
    • Billiar, T.R.1    Curran, R.D.2    Stuehr, D.J.3    West, M.A.4    Bentz, B.G.5    Simmons, R.L.6
  • 77
    • 0026080917 scopus 로고
    • Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion
    • Caldwell-Kenkel, J. C., Currin, R. T., Tanaka, Y., Thurman, R. G., Lemasters, J. J. (1991) Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion. Hepatology 13, 83-95.
    • (1991) Hepatology , vol.13 , pp. 83-95
    • Caldwell-Kenkel, J.C.1    Currin, R.T.2    Tanaka, Y.3    Thurman, R.G.4    Lemasters, J.J.5
  • 78
    • 0035087819 scopus 로고    scopus 로고
    • A coculture model of intrahepatic islet transplantation: Activation of Kupffer cells by islets and acinar tissue
    • Clayton, H. A., Davies, J. E., Sutton, C. D., Bell, P. R., Dennison, A. R. (2001) A coculture model of intrahepatic islet transplantation: activation of Kupffer cells by islets and acinar tissue. Cell Transplant. 10, 101-108.
    • (2001) Cell Transplant. , vol.10 , pp. 101-108
    • Clayton, H.A.1    Davies, J.E.2    Sutton, C.D.3    Bell, P.R.4    Dennison, A.R.5
  • 79
    • 0025358131 scopus 로고
    • Role of tumor necrosis factor-α in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat
    • Colletti, L. M., Remick, D. G., Burtch, G. D., Kunkel, S. L., Strieter, R. M., Campbell Jr., D. A. (1990) Role of tumor necrosis factor-α in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J. Clin. Invest. 85, 1936-1943.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1936-1943
    • Colletti, L.M.1    Remick, D.G.2    Burtch, G.D.3    Kunkel, S.L.4    Strieter, R.M.5    Campbell Jr., D.A.6
  • 81
    • 0023692456 scopus 로고
    • Exocrine contamination impairs implantation of pancreatic islets transplanted beneath the kidney capsule
    • Gray, D. W., Sutton, R., McShane, P., Peters, M., Morris, P. J. (1988) Exocrine contamination impairs implantation of pancreatic islets transplanted beneath the kidney capsule. J. Surg. Res. 45, 432-442.
    • (1988) J. Surg. Res. , vol.45 , pp. 432-442
    • Gray, D.W.1    Sutton, R.2    McShane, P.3    Peters, M.4    Morris, P.J.5
  • 83
    • 0021241575 scopus 로고
    • Macrophage-mediated cytotoxicity against cultured pancreatic islet cells
    • Schwizer, R. W., Leiter, E. H., Evans, R. (1984) Macrophage-mediated cytotoxicity against cultured pancreatic islet cells. Transplantation 37, 539-544.
    • (1984) Transplantation , vol.37 , pp. 539-544
    • Schwizer, R.W.1    Leiter, E.H.2    Evans, R.3
  • 84
    • 0030997703 scopus 로고    scopus 로고
    • Interferon-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
    • Heitmeier, M. R., Scarim, A. L., Corbett, J. A. (1997) Interferon-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. J. Biol. Chem. 272, 13697-13704.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13697-13704
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 86
    • 0033617148 scopus 로고    scopus 로고
    • Double-stranded RNA inhibits β-cell function and induces islet damage by stimulating β-cell production of nitric oxide
    • Heitmeier, M. R., Scarim, A. L., Corbett, J. A. (1999) Double-stranded RNA inhibits β-cell function and induces islet damage by stimulating β-cell production of nitric oxide. J. Biol. Chem. 274, 12531-12536.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12531-12536
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 87
    • 0025802116 scopus 로고
    • Activation of intraislet lymphoid cells causes destruction of islet cells
    • Lacy, P. E., Finke, E. H. (1991) Activation of intraislet lymphoid cells causes destruction of islet cells. Am. J. Pathol. 138, 1183-1190.
    • (1991) Am. J. Pathol. , vol.138 , pp. 1183-1190
    • Lacy, P.E.1    Finke, E.H.2
  • 88
    • 0018839623 scopus 로고
    • Blood flow to the rabbit pancreas with special reference to the islets of Langerhans
    • Lifson, N., Kramlinger, K. G., Mayrand, R. R., Lender, E. J. (1980) Blood flow to the rabbit pancreas with special reference to the islets of Langerhans. Gastroenterology 79, 466-473.
    • (1980) Gastroenterology , vol.79 , pp. 466-473
    • Lifson, N.1    Kramlinger, K.G.2    Mayrand, R.R.3    Lender, E.J.4
  • 89
    • 0020570005 scopus 로고
    • Stimulation by glucose of the blood flow to the pancreatic islets of the rat
    • Jansson, L., Hellerstrom, C. (1983) Stimulation by glucose of the blood flow to the pancreatic islets of the rat. Diabetologia 25, 45-50.
    • (1983) Diabetologia , vol.25 , pp. 45-50
    • Jansson, L.1    Hellerstrom, C.2
  • 90
    • 0029618302 scopus 로고
    • Hormone secretion from transplanted islets is dependent upon changes in islet revascularization and islet architecture
    • Stagner, J. I., Mokshagundam, S., Samols, E. (1995) Hormone secretion from transplanted islets is dependent upon changes in islet revascularization and islet architecture. Transplant. Proc. 27, 3251-3254.
    • (1995) Transplant. Proc. , vol.27 , pp. 3251-3254
    • Stagner, J.I.1    Mokshagundam, S.2    Samols, E.3
  • 91
    • 0020060298 scopus 로고
    • Portal hypertension, hepatic infarction, and liver failure complicating pancreatic islet autotransplantation
    • Walsh, T. J., Eggleston, J. C., Cameron, J. L. (1982) Portal hypertension, hepatic infarction, and liver failure complicating pancreatic islet autotransplantation. Surgery 91, 485-487.
    • (1982) Surgery , vol.91 , pp. 485-487
    • Walsh, T.J.1    Eggleston, J.C.2    Cameron, J.L.3
  • 93
    • 0025332279 scopus 로고
    • The induction of capillary bed development by endothelial cell growth factor before islet transplantation may prevent islet ischemia
    • Stagner, J. I., Samols, E. (1990) The induction of capillary bed development by endothelial cell growth factor before islet transplantation may prevent islet ischemia. Transplant. Proc. 22, 824-828.
    • (1990) Transplant. Proc. , vol.22 , pp. 824-828
    • Stagner, J.I.1    Samols, E.2
  • 94
    • 0018886050 scopus 로고
    • Cellular changes in cultured mouse thyroid glands and islets of Langerhans
    • Parr, E. L., Bowen, K. M., Lafferty, K. J. (1980) Cellular changes in cultured mouse thyroid glands and islets of Langerhans. Transplantation 30, 135-141.
    • (1980) Transplantation , vol.30 , pp. 135-141
    • Parr, E.L.1    Bowen, K.M.2    Lafferty, K.J.3
  • 95
    • 0031737796 scopus 로고    scopus 로고
    • Hypoxia induces vascular endothelial growth factor gene and protein expression in cultured rat islet cells
    • Vasir, B., Aiello, L. P., Yoon, K. H., Quickel, R. R., Bonner-Weir, S., Weir, G. C. (1998) Hypoxia induces vascular endothelial growth factor gene and protein expression in cultured rat islet cells. Diabetes 47, 1894-1903.
    • (1998) Diabetes , vol.47 , pp. 1894-1903
    • Vasir, B.1    Aiello, L.P.2    Yoon, K.H.3    Quickel, R.R.4    Bonner-Weir, S.5    Weir, G.C.6
  • 96
    • 0029008066 scopus 로고
    • Histogenesis and ultrastructure of pancreatic islet graft microvasculature. Evidence for graft revascularization by endothelial cells of host origin
    • Vajkoczy, P., Olofsson, A. M., Lehr, H. A., Leiderer, R., Hammersen, F., Arfors, K. E., Menger, M. D. (1995) Histogenesis and ultrastructure of pancreatic islet graft microvasculature. Evidence for graft revascularization by endothelial cells of host origin. Am. J. Pathol. 146, 1397-1405.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1397-1405
    • Vajkoczy, P.1    Olofsson, A.M.2    Lehr, H.A.3    Leiderer, R.4    Hammersen, F.5    Arfors, K.E.6    Menger, M.D.7
  • 97
    • 0029146628 scopus 로고
    • Angiogenesis and vascularization of murine pancreatic islet isografts
    • Vajkoczy, P., Menger, M. D., Simpson, E., Messmer, K. (1995) Angiogenesis and vascularization of murine pancreatic islet isografts. Transplantation 60, 123-127.
    • (1995) Transplantation , vol.60 , pp. 123-127
    • Vajkoczy, P.1    Menger, M.D.2    Simpson, E.3    Messmer, K.4
  • 98
    • 0030982214 scopus 로고    scopus 로고
    • Angiogenesis in cultured and cryopreserved pancreatic islet grafts
    • Merchant, F. A., Diller, K. R., Aggarwal, S. J., Bovik, A. C. (1997) Angiogenesis in cultured and cryopreserved pancreatic islet grafts. Transplantation 63, 1652-1660.
    • (1997) Transplantation , vol.63 , pp. 1652-1660
    • Merchant, F.A.1    Diller, K.R.2    Aggarwal, S.J.3    Bovik, A.C.4
  • 99
    • 0027533914 scopus 로고
    • Hepatic arterial and portal venous oxygen content and extraction in liver cirrhosis
    • Sezai, S., Sakurabayashi, S., Yamamoto, Y., Morita, T., Hirano, M., Oka, H. (1993) Hepatic arterial and portal venous oxygen content and extraction in liver cirrhosis. Liver 13, 31-35.
    • (1993) Liver , vol.13 , pp. 31-35
    • Sezai, S.1    Sakurabayashi, S.2    Yamamoto, Y.3    Morita, T.4    Hirano, M.5    Oka, H.6
  • 100
    • 0031780344 scopus 로고    scopus 로고
    • Measurements of oxygen tension in native and transplanted rat pancreatic islets
    • Carlsson, P. O., Liss, P., Andersson, A., Jansson, L. (1998) Measurements of oxygen tension in native and transplanted rat pancreatic islets. Diabetes 47, 1027-1032.
    • (1998) Diabetes , vol.47 , pp. 1027-1032
    • Carlsson, P.O.1    Liss, P.2    Andersson, A.3    Jansson, L.4
  • 101
    • 0035120134 scopus 로고    scopus 로고
    • Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site
    • Carlsson, P. O., Palm, F., Andersson, A., Liss, P. (2001) Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50, 489-495.
    • (2001) Diabetes , vol.50 , pp. 489-495
    • Carlsson, P.O.1    Palm, F.2    Andersson, A.3    Liss, P.4
  • 102
    • 0036933569 scopus 로고    scopus 로고
    • Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants
    • Carlsson, P. O., Palm, F. (2002) Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants. Transpl. Int. 15, 581-585.
    • (2002) Transpl. Int. , vol.15 , pp. 581-585
    • Carlsson, P.O.1    Palm, F.2
  • 103
    • 0034654596 scopus 로고    scopus 로고
    • Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule
    • Carlsson, P. O., Palm, F., Andersson, A., Liss, P. (2000) Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule. Transplantation 69, 761-766.
    • (2000) Transplantation , vol.69 , pp. 761-766
    • Carlsson, P.O.1    Palm, F.2    Andersson, A.3    Liss, P.4
  • 104
    • 0027470723 scopus 로고
    • Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans
    • Dionne, K. E., Colton, C. K., Yarmush, M. L. (1993) Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes 42, 12-21.
    • (1993) Diabetes , vol.42 , pp. 12-21
    • Dionne, K.E.1    Colton, C.K.2    Yarmush, M.L.3
  • 105
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function
    • Davalli, A. M., Scaglia, L., Zangen, D. H., Hollister, J., Bonner-Weir, S., Weir, G. C. (1996) Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45, 1161-1167.
    • (1996) Diabetes , vol.45 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 106
    • 18244386157 scopus 로고    scopus 로고
    • Central cell death in isolated pancreatic islets is inherent to their spherical structure
    • Han, D. J., Kim, S. C., Wee, Y. M. (2003) Central cell death in isolated pancreatic islets is inherent to their spherical structure. Transplantation 76 (Suppl. 4), S67-S68.
    • (2003) Transplantation , vol.76 , Issue.SUPPL. 4
    • Han, D.J.1    Kim, S.C.2    Wee, Y.M.3
  • 107
    • 0035987883 scopus 로고    scopus 로고
    • Beneficial effects of hyperbaric oxygen therapy on islet transplantation
    • Juang, J. H., Hsu, B. R., Kuo, C. H., Uengt, S. W. (2002) Beneficial effects of hyperbaric oxygen therapy on islet transplantation. Cell Transplant. 11, 95-101.
    • (2002) Cell Transplant , vol.11 , pp. 95-101
    • Juang, J.H.1    Hsu, B.R.2    Kuo, C.H.3    Uengt, S.W.4
  • 108
    • 0022510439 scopus 로고
    • Contributions of ischemia and reperfusion to mucosal lesion formation
    • Parks, D. A., Granger, D. N. (1986) Contributions of ischemia and reperfusion to mucosal lesion formation. Am. J. Physiol. 250, G749-G753.
    • (1986) Am. J. Physiol. , vol.250
    • Parks, D.A.1    Granger, D.N.2
  • 109
    • 0024559102 scopus 로고
    • Hypoxic reperfusion attenuates postischemic microvascular injury
    • Korthuis, R. J., Smith, J. K., Carden, D. L. (1989) Hypoxic reperfusion attenuates postischemic microvascular injury. Am. J. Physiol. 256, H315-H319.
    • (1989) Am. J. Physiol. , vol.256
    • Korthuis, R.J.1    Smith, J.K.2    Carden, D.L.3
  • 111
    • 0034053099 scopus 로고    scopus 로고
    • Pathophysiology of ischaemia-reperfusion injury
    • Carden, D. L., Granger, D. N. (2000) Pathophysiology of ischaemia-reperfusion injury. J. Pathol. 190, 255-266.
    • (2000) J. Pathol. , vol.190 , pp. 255-266
    • Carden, D.L.1    Granger, D.N.2
  • 112
    • 0024455295 scopus 로고
    • Intercellular adhesion molecule 1 on liver allografts during rejection
    • Adams, D. H., Hubscher, S. G., Shaw, J., Rothlein, R., Neuberger, J. M. (1989) Intercellular adhesion molecule 1 on liver allografts during rejection. Lancet 2, 1122-1125.
    • (1989) Lancet , vol.2 , pp. 1122-1125
    • Adams, D.H.1    Hubscher, S.G.2    Shaw, J.3    Rothlein, R.4    Neuberger, J.M.5
  • 113
    • 0030834405 scopus 로고    scopus 로고
    • Molecular mechanisms of anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells
    • Ichikawa, H., Flores, S., Kvietys, P. R., Wolf, R. E., Yoshikawa, T., Granger, D. N., Aw, T. Y. (1997) Molecular mechanisms of anoxia/reoxygenation- induced neutrophil adherence to cultured endothelial cells. Circ. Res. 81, 922-931.
    • (1997) Circ. Res. , vol.81 , pp. 922-931
    • Ichikawa, H.1    Flores, S.2    Kvietys, P.R.3    Wolf, R.E.4    Yoshikawa, T.5    Granger, D.N.6    Aw, T.Y.7
  • 116
    • 0344088433 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-γ expression in splenic T cells
    • Augstein, P., Dunger, A., Heinke, P., Wachlin, G., Berg, S., Hehmke, B., Salzsieder, E. (2003) Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-γ expression in splenic T cells. Biochem. Biophys. Res. Commun. 304, 378-384.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , pp. 378-384
    • Augstein, P.1    Dunger, A.2    Heinke, P.3    Wachlin, G.4    Berg, S.5    Hehmke, B.6    Salzsieder, E.7
  • 117
    • 0029744325 scopus 로고    scopus 로고
    • Control of islet intercellular adhesion molecule-1 expression by interferon-α and hypoxia
    • Chakrabarti, D., Huang, X., Beck, J., Henrich, J., McFarland, N., James, R. F., Stewart, T. A. (1996) Control of islet intercellular adhesion molecule-1 expression by interferon-α and hypoxia. Diabetes 45, 1336-1343.
    • (1996) Diabetes , vol.45 , pp. 1336-1343
    • Chakrabarti, D.1    Huang, X.2    Beck, J.3    Henrich, J.4    McFarland, N.5    James, R.F.6    Stewart, T.A.7
  • 119
    • 0037354853 scopus 로고    scopus 로고
    • Proinflammatory cytokines induce NF-κB-dependent/NO-independent chemokine gene expression in MIN6 β cells
    • Baker, M. S., Chen, X., Rotramel, A., Nelson, J., Kaufman, D. B. (2003) Proinflammatory cytokines induce NF-κB-dependent/NO-independent chemokine gene expression in MIN6 β cells. J. Surg. Res. 110, 295-303.
    • (2003) J. Surg. Res. , vol.110 , pp. 295-303
    • Baker, M.S.1    Chen, X.2    Rotramel, A.3    Nelson, J.4    Kaufman, D.B.5
  • 120
    • 0022555858 scopus 로고
    • Platelet activating factor: A biologically active phosphoglyceride
    • Hanahan, D. J. (1986) Platelet activating factor: a biologically active phosphoglyceride. Annu. Rev. Biochem. 55, 483-509.
    • (1986) Annu. Rev. Biochem. , vol.55 , pp. 483-509
    • Hanahan, D.J.1
  • 121
    • 0023774854 scopus 로고
    • Cytokine-induced procoagulant activity in monocytes and endothelial cells. Further enhancement by cyclosporine
    • Carlsen, E., Flatmark, A., Prydz, H. (1988) Cytokine-induced procoagulant activity in monocytes and endothelial cells. Further enhancement by cyclosporine. Transplantation 46, 575-580.
    • (1988) Transplantation , vol.46 , pp. 575-580
    • Carlsen, E.1    Flatmark, A.2    Prydz, H.3
  • 122
    • 0025348272 scopus 로고
    • Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties
    • Ogawa, S., Gerlach, H., Esposito, C., Pasagian-Macaulay, A., Brett, J., Stern, D. (1990) Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties. J. Clin. Invest. 85, 1090-1098.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1090-1098
    • Ogawa, S.1    Gerlach, H.2    Esposito, C.3    Pasagian-Macaulay, A.4    Brett, J.5    Stern, D.6
  • 123
    • 0031657396 scopus 로고    scopus 로고
    • Role of tissue factor in ischemic reperfusion injury: iv). The effect of tissue factor pathway inhibitor on the survival rate in vivo
    • Yoshimura, N., Kobayashi, Y., Nakamura, K., Yoshimura, R., Yamagishi, H., Oka, T. (1998) Role of tissue factor in ischemic reperfusion injury: iv). The effect of tissue factor pathway inhibitor on the survival rate in vivo. Transplant. Proc. 30, 2300-2301.
    • (1998) Transplant. Proc. , vol.30 , pp. 2300-2301
    • Yoshimura, N.1    Kobayashi, Y.2    Nakamura, K.3    Yoshimura, R.4    Yamagishi, H.5    Oka, T.6
  • 124
    • 1442310594 scopus 로고    scopus 로고
    • Tissue factor: A key molecule in hemostatic and nonhemostatic systems
    • Morrissey, J. H. (2004) Tissue factor: a key molecule in hemostatic and nonhemostatic systems. Int. J. Hematol. 79, 103-108.
    • (2004) Int. J. Hematol. , vol.79 , pp. 103-108
    • Morrissey, J.H.1
  • 125
    • 0022601049 scopus 로고
    • Modulation of endothelial cell hemostatic properties by tumor necrosis factor
    • Nawroth, P. P., Stern, D. M. (1986) Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J. Exp. Med. 163, 740-745.
    • (1986) J. Exp. Med. , vol.163 , pp. 740-745
    • Nawroth, P.P.1    Stern, D.M.2
  • 127
    • 0026696101 scopus 로고
    • Islet cell allotransplantation in diabetic patients. Histologic findings in four adults simultaneously receiving kidney or liver transplants
    • Sever, C. E., Demetris, A. J., Zeng, Y., Tzakis, A., Fung, J. J., Starzl, T. E., Ricordi, C. (1992) Islet cell allotransplantation in diabetic patients. Histologic findings in four adults simultaneously receiving kidney or liver transplants. Am. J. Pathol. 140, 1255-1260.
    • (1992) Am. J. Pathol. , vol.140 , pp. 1255-1260
    • Sever, C.E.1    Demetris, A.J.2    Zeng, Y.3    Tzakis, A.4    Fung, J.J.5    Starzl, T.E.6    Ricordi, C.7
  • 128
    • 0029837105 scopus 로고    scopus 로고
    • Blood coagulation in the hepatic sinusoids as a contributing factor in liver injury following orthotopic liver transplantation in the rat
    • Arai, M., Mochida, S., Ohno, A., Fujiwara, K. (1996) Blood coagulation in the hepatic sinusoids as a contributing factor in liver injury following orthotopic liver transplantation in the rat. Transplantation 62, 1398-1401.
    • (1996) Transplantation , vol.62 , pp. 1398-1401
    • Arai, M.1    Mochida, S.2    Ohno, A.3    Fujiwara, K.4
  • 131
    • 0036263218 scopus 로고    scopus 로고
    • Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: Possible application of the thrombin inhibitor melagatran in clinical islet transplantation
    • Ozmen, L., Ekdahl, K. N., Elgue, G., Larsson, R., Korsgren, O., Nilsson, B. (2002) Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 51, 1779-1784.
    • (2002) Diabetes , vol.51 , pp. 1779-1784
    • Ozmen, L.1    Ekdahl, K.N.2    Elgue, G.3    Larsson, R.4    Korsgren, O.5    Nilsson, B.6
  • 133
    • 0036925183 scopus 로고    scopus 로고
    • Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using Edmonton protocol immunosuppression
    • Hirshberg, B., Mog, S., Patterson, N., Leconte, J., Harlan, D. M. (2002) Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using Edmonton protocol immunosuppression. J. Clin. Endocrinol. Metab. 87, 5424-5429.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 5424-5429
    • Hirshberg, B.1    Mog, S.2    Patterson, N.3    Leconte, J.4    Harlan, D.M.5
  • 135
    • 0024365898 scopus 로고
    • Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells
    • Curran, R. D., Billiar, T. R., Stuehr, D. J., Hofmann, K., Simmons, R. L. (1989) Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. J. Exp. Med. 170, 1769-1774.
    • (1989) J. Exp. Med. , vol.170 , pp. 1769-1774
    • Curran, R.D.1    Billiar, T.R.2    Stuehr, D.J.3    Hofmann, K.4    Simmons, R.L.5
  • 136
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • Tenhunen, R., Marver, H. S., Schmid, R. (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. USA 61, 748-755.
    • (1968) Proc. Natl. Acad. Sci. USA , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 137
    • 0027534465 scopus 로고
    • Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene
    • Rizzardini, M., Terao, M., Falciani, F., Cantoni, L. (1993) Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene. Biochem. J. 290, 343-347.
    • (1993) Biochem. J. , vol.290 , pp. 343-347
    • Rizzardini, M.1    Terao, M.2    Falciani, F.3    Cantoni, L.4
  • 138
    • 0030961521 scopus 로고    scopus 로고
    • Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells
    • Durante, W., Kroll, M. H., Christodoulides, N., Peyton, K. J., Schafer, A. I. (1997) Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ. Res. 80, 557-564.
    • (1997) Circ. Res. , vol.80 , pp. 557-564
    • Durante, W.1    Kroll, M.H.2    Christodoulides, N.3    Peyton, K.J.4    Schafer, A.I.5
  • 139
    • 0035179294 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects pancreatic β cells from apoptosis caused by various stimuli
    • Tobiasch, E., Gunther, L., Bach, F. H. (2001) Heme oxygenase-1 protects pancreatic β cells from apoptosis caused by various stimuli. J. Investig. Med. 49, 566-571.
    • (2001) J. Investig. Med. , vol.49 , pp. 566-571
    • Tobiasch, E.1    Gunther, L.2    Bach, F.H.3
  • 140
    • 15644379473 scopus 로고    scopus 로고
    • A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1β
    • Ye, J., Laychock, S. G. (1998) A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1β. Endocrinology 139, 4155-4163.
    • (1998) Endocrinology , vol.139 , pp. 4155-4163
    • Ye, J.1    Laychock, S.G.2
  • 143
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • Stocker, R., Yamamoto, Y., McDonagh, A. F., Glazer, A. N., Ames, B. N. (1987) Bilirubin is an antioxidant of possible physiological importance. Science 235, 1043-1046.
    • (1987) Science , vol.235 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3    Glazer, A.N.4    Ames, B.N.5
  • 144
    • 0036226971 scopus 로고    scopus 로고
    • Carbon monoxide protects pancreatic β-cells from apoptosis and improves islet function/survival after transplantation
    • Gunther, L., Berberat, P. O., Haga, M., Brouard, S., Smith, R. N., Soares, M. P., Bach, F. H., Tobiasch, E. (2002) Carbon monoxide protects pancreatic β-cells from apoptosis and improves islet function/survival after transplantation. Diabetes 51, 994-999.
    • (2002) Diabetes , vol.51 , pp. 994-999
    • Gunther, L.1    Berberat, P.O.2    Haga, M.3    Brouard, S.4    Smith, R.N.5    Soares, M.P.6    Bach, F.H.7    Tobiasch, E.8
  • 146
    • 0034659113 scopus 로고    scopus 로고
    • IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse
    • Balasa, B., Van Gunst, K., Jung, N., Katz, J. D., Sarvetnick, N. (2000) IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide- induced diabetes in the nonobese diabetic mouse. Cell. Immunol. 202, 97-102.
    • (2000) Cell. Immunol. , vol.202 , pp. 97-102
    • Balasa, B.1    Van Gunst, K.2    Jung, N.3    Katz, J.D.4    Sarvetnick, N.5
  • 147
    • 0028222756 scopus 로고
    • Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
    • Pennline, K. J., Roque-Gaffney, E., Monahan, M. (1994) Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. Clin. Immunol. Immunopathol. 71, 169-175.
    • (1994) Clin. Immunol. Immunopathol. , vol.71 , pp. 169-175
    • Pennline, K.J.1    Roque-Gaffney, E.2    Monahan, M.3
  • 149
    • 0030773969 scopus 로고    scopus 로고
    • Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent β cell destruction in diabetic NOD mice
    • Smith, D. K., Korbutt, G. S., Suarez-Pinzon, W. L., Kao, D., Rajotte, R. V., Elliott, J. F. (1997) Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent β cell destruction in diabetic NOD mice. Transplantation 64, 1040-1049.
    • (1997) Transplantation , vol.64 , pp. 1040-1049
    • Smith, D.K.1    Korbutt, G.S.2    Suarez-Pinzon, W.L.3    Kao, D.4    Rajotte, R.V.5    Elliott, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.