-
1
-
-
0035668779
-
A choice of death: The signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T: A choice of death: the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 44:2115-2133, 2001
-
(2001)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
2
-
-
0042839568
-
Role of cytokines in the pathogenesis of autoimmune diabetes mellitus
-
Rabinovitch A, Suarez-Pinzon WL: Role of cytokines in the pathogenesis of autoimmune diabetes mellitus. Rev Endocr Metab Disord 4:291-299, 2003
-
(2003)
Rev Endocr Metab Disord
, vol.4
, pp. 291-299
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
3
-
-
0036068246
-
Interleukin-1 plus -γ-inter- feron-induced pancreatic β-cell dysfunction is mediated by β-cell nitric oxide production
-
Thomas HE, Darwiche R, Corbett JA, Kay TW: Interleukin-1 plus -γ-inter- feron-induced pancreatic β-cell dysfunction is mediated by β-cell nitric oxide production. Diabetes 51:311-316, 2002
-
(2002)
Diabetes
, vol.51
, pp. 311-316
-
-
Thomas, H.E.1
Darwiche, R.2
Corbett, J.A.3
Kay, T.W.4
-
4
-
-
0028181046
-
Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase
-
Corbett JA, McDaniel ML: Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase. Biochem J 299:719-724, 1994
-
(1994)
Biochem J
, vol.299
, pp. 719-724
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
5
-
-
33644749322
-
Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
Cnop M, Welsh N, Jonas JC, Jorns A, Lenzen S, Eizirik DL: Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54:S97-S107, 2005
-
(2005)
Diabetes
, vol.54
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jorns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
6
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway
-
Oyadomari S, Takeda K, Takiguchi M, Gotoh T, Matsumoto M, Wada I, Akira S, Araki E, Mori M: Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Nat Acad Sci USA 98:10845-10850, 2001
-
(2001)
Proc Nat Acad Sci USA
, vol.98
, pp. 10845-10850
-
-
Oyadomari, S.1
Takeda, K.2
Takiguchi, M.3
Gotoh, T.4
Matsumoto, M.5
Wada, I.6
Akira, S.7
Araki, E.8
Mori, M.9
-
7
-
-
19944432792
-
2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells
-
2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells. Diabetes 54:452-461, 2005
-
(2005)
Diabetes
, vol.54
, pp. 452-461
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
Feng, Y.M.4
Rasschaert, J.5
Tonnesen, M.6
Van Eylen, F.7
Mandrup-Poulsen, T.8
Herchuelz, A.9
Eizirik, D.L.10
-
8
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
-
Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL: Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 145:5087-5096, 2004
-
(2004)
Endocrinology
, vol.145
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladriere, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
Eizirik, D.L.6
-
9
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D, Walter P: Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-529, 2007
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
10
-
-
33645156429
-
From acute ER stress to physiological roles of the unfolded protein response
-
Wu J, Kaufman RJ: From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 13:374-384, 2006
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
11
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D: Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2:326-332, 2000
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
12
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D: Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6:1099-1108, 2000
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
13
-
-
8944259440
-
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
-
Wang XZ, Lawson B, Brewer JW, Zinszner H, Sanjay A, Mi LJ, Boorstein R, Kreibich G, Hendershot LM, Ron D: Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol 16:4273-4280, 1996
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4273-4280
-
-
Wang, X.Z.1
Lawson, B.2
Brewer, J.W.3
Zinszner, H.4
Sanjay, A.5
Mi, L.J.6
Boorstein, R.7
Kreibich, G.8
Hendershot, L.M.9
Ron, D.10
-
14
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
-
Oyadomari S, Koizumi A, Takeda K, Gotoh T, Akira S, Araki E, Mori M: Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest 109:525-532, 2002
-
(2002)
J Clin Invest
, vol.109
, pp. 525-532
-
-
Oyadomari, S.1
Koizumi, A.2
Takeda, K.3
Gotoh, T.4
Akira, S.5
Araki, E.6
Mori, M.7
-
15
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S, Mori M: Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11:381-389, 2004
-
(2004)
Cell Death Differ
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
16
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
-
Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D: Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol cell 1153-1163, 2001
-
(2001)
Mol cell
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
17
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ: Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 7:1165-1176, 2001
-
(2001)
Mol Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
18
-
-
22544444513
-
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
-
Scheuner D, Mierde DV, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ: Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nat Med 11:757-764, 2005
-
(2005)
Nat Med
, vol.11
, pp. 757-764
-
-
Scheuner, D.1
Mierde, D.V.2
Song, B.3
Flamez, D.4
Creemers, J.W.5
Tsukamoto, K.6
Ribick, M.7
Schuit, F.C.8
Kaufman, R.J.9
-
19
-
-
33847677975
-
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
-
Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ: Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes. Diabetologia 50:752-763, 2007
-
(2007)
Diabetologia
, vol.50
, pp. 752-763
-
-
Laybutt, D.R.1
Preston, A.M.2
Akerfeldt, M.C.3
Kench, J.G.4
Busch, A.K.5
Biankin, A.V.6
Biden, T.J.7
-
20
-
-
34547638958
-
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
-
Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC: High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 56:2016-2027, 2007
-
(2007)
Diabetes
, vol.56
, pp. 2016-2027
-
-
Huang, C.J.1
Lin, C.Y.2
Haataja, L.3
Gurlo, T.4
Butler, A.E.5
Rizza, R.A.6
Butler, P.C.7
-
21
-
-
25844454854
-
Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic β,-cells from lipoapoptosis
-
Busch AK, Gurisik E, Cordery DV, Sudlow M, Denyer GS, Laybutt DR, Hughes WE, Biden TJ: Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic β,-cells from lipoapoptosis. Diabetes 54:2917-2924, 2005
-
(2005)
Diabetes
, vol.54
, pp. 2917-2924
-
-
Busch, A.K.1
Gurisik, E.2
Cordery, D.V.3
Sudlow, M.4
Denyer, G.S.5
Laybutt, D.R.6
Hughes, W.E.7
Biden, T.J.8
-
22
-
-
0037009521
-
A mitochondrial specific stress response in mammalian cells
-
Zhao Q, Wang J, Levichkin IV, Stasinopoulos S, Ryan MT, Hoogenraad NJ: A mitochondrial specific stress response in mammalian cells. Embo J 21:4411-4419, 2002
-
(2002)
Embo J
, vol.21
, pp. 4411-4419
-
-
Zhao, Q.1
Wang, J.2
Levichkin, I.V.3
Stasinopoulos, S.4
Ryan, M.T.5
Hoogenraad, N.J.6
-
23
-
-
24144496798
-
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
-
Kjorholt C, Akerfeldt MC, Biden TJ, Laybutt DR: Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes 54:2755-2763, 2005
-
(2005)
Diabetes
, vol.54
, pp. 2755-2763
-
-
Kjorholt, C.1
Akerfeldt, M.C.2
Biden, T.J.3
Laybutt, D.R.4
-
24
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Gorgun CZ, Hotamisligil GS: Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140, 2006
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
25
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D: Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287:664-666, 2000
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
26
-
-
0026511824
-
Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells
-
Dorner AJ, Wasley LC, Kaufman RJ: Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells. Embo J 11:1563-1571,1992
-
(1992)
Embo J
, vol.11
, pp. 1563-1571
-
-
Dorner, A.J.1
Wasley, L.C.2
Kaufman, R.J.3
-
27
-
-
0037023726
-
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
-
Gotoh T, Oyadomari S, Mori K, Mori M: Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J Biol Chem 277:12343-12350, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 12343-12350
-
-
Gotoh, T.1
Oyadomari, S.2
Mori, K.3
Mori, M.4
-
28
-
-
0035879276
-
Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms
-
Maytin EV, Ubeda M, Lin JC, Habener JF: Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms. Exp Cell Res 267:193-204, 2001
-
(2001)
Exp Cell Res
, vol.267
, pp. 193-204
-
-
Maytin, E.V.1
Ubeda, M.2
Lin, J.C.3
Habener, J.F.4
-
29
-
-
0030597160
-
Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells
-
Matsumoto M, Minami M, Takeda K, Sakao Y, Akira S: Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells. FEBS Lett 395:143-147, 1996
-
(1996)
FEBS Lett
, vol.395
, pp. 143-147
-
-
Matsumoto, M.1
Minami, M.2
Takeda, K.3
Sakao, Y.4
Akira, S.5
-
30
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ: Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21:1249-1259, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
31
-
-
33750448469
-
GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress
-
Yusta B, Baggio LL, Estall JL, Koehler JA, Holland DP, Li H, Pipeleers D, Ling Z, Drucker DJ: GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress. Cell Metab 4:391-406, 2006
-
(2006)
Cell Metab
, vol.4
, pp. 391-406
-
-
Yusta, B.1
Baggio, L.L.2
Estall, J.L.3
Koehler, J.A.4
Holland, D.P.5
Li, H.6
Pipeleers, D.7
Ling, Z.8
Drucker, D.J.9
-
32
-
-
0037219411
-
β-Cell deficit and increased p-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC: β-Cell deficit and increased p-cell apoptosis in humans with type 2 diabetes. Diabetes 52:102-110, 2003
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
33
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS: Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457-461, 2004
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
34
-
-
33745116619
-
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis
-
Karaskov E, Scott C, Zhang L, Teodoro T, Ravazzola M, Volchuk A: Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology 147:3398-3407, 2006
-
(2006)
Endocrinology
, vol.147
, pp. 3398-3407
-
-
Karaskov, E.1
Scott, C.2
Zhang, L.3
Teodoro, T.4
Ravazzola, M.5
Volchuk, A.6
-
35
-
-
33646533330
-
Interferon-gamma potentiates endoplas- mic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms
-
Pirot P, Eizirik DL, Cardozo AK: Interferon-gamma potentiates endoplas- mic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms. Diabetologia 49:1229-1236, 2006
-
(2006)
Diabetologia
, vol.49
, pp. 1229-1236
-
-
Pirot, P.1
Eizirik, D.L.2
Cardozo, A.K.3
-
36
-
-
34047235220
-
Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells
-
Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL, Cardozo AK: Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells. Diabetes 56:1069-1077, 2007
-
(2007)
Diabetes
, vol.56
, pp. 1069-1077
-
-
Pirot, P.1
Ortis, F.2
Cnop, M.3
Ma, Y.4
Hendershot, L.M.5
Eizirik, D.L.6
Cardozo, A.K.7
-
37
-
-
33947510911
-
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid- induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis
-
Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL: Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid- induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. J Biol Chem 282:3989-3997, 2007
-
(2007)
J Biol Chem
, vol.282
, pp. 3989-3997
-
-
Cnop, M.1
Ladriere, L.2
Hekerman, P.3
Ortis, F.4
Cardozo, A.K.5
Dogusan, Z.6
Flamez, D.7
Boyce, M.8
Yuan, J.9
Eizirik, D.L.10
-
38
-
-
8544267219
-
PPARgammaligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling
-
Weber SM, Chambers KT, Bensch KG, Scarim AL, Corbett JA: PPARgammaligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling. Am J Physiol Endocrinol Metab 287:E1171-E1177, 2004
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Weber, S.M.1
Chambers, K.T.2
Bensch, K.G.3
Scarim, A.L.4
Corbett, J.A.5
-
39
-
-
38449122843
-
The role of nitric oxide and the unfolded protein response in cytokine-induced β-cell death
-
Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA: The role of nitric oxide and the unfolded protein response in cytokine-induced β-cell death. Diabetes 57:124-132, 2008
-
(2008)
Diabetes
, vol.57
, pp. 124-132
-
-
Chambers, K.T.1
Unverferth, J.A.2
Weber, S.M.3
Wek, R.C.4
Urano, F.5
Corbett, J.A.6
-
40
-
-
34548381411
-
Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes
-
Wang M, Zhao XR, Wang P, Li L, Dai Y, Huang H, Lei P, Zhu HF, Shen GX: Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes. Int J Biochem Cell Biol 39:2076-2082, 2007
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 2076-2082
-
-
Wang, M.1
Zhao, X.R.2
Wang, P.3
Li, L.4
Dai, Y.5
Huang, H.6
Lei, P.7
Zhu, H.F.8
Shen, G.X.9
-
41
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
-
Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF: Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death. Diabetes 50:77-82, 2001
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
42
-
-
26244436171
-
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
-
Storling J, Binzer J, Andersson AK, Zullig RA, Tonnesen M, Lehmann R, Spinas GA, Sandler S, Billestrup N, Mandrup-Poulsen T: Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt. Diabetologia 48:2039-2050, 2005
-
(2005)
Diabetologia
, vol.48
, pp. 2039-2050
-
-
Storling, J.1
Binzer, J.2
Andersson, A.K.3
Zullig, R.A.4
Tonnesen, M.5
Lehmann, R.6
Spinas, G.A.7
Sandler, S.8
Billestrup, N.9
Mandrup-Poulsen, T.10
-
43
-
-
42449126643
-
Inhibition of Foxo1 protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis
-
Martinez SC, Tanabe K, Cras-Meneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA: Inhibition of Foxo1 protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis. Diabetes 57:846-859, 2008
-
(2008)
Diabetes
, vol.57
, pp. 846-859
-
-
Martinez, S.C.1
Tanabe, K.2
Cras-Meneur, C.3
Abumrad, N.A.4
Bernal-Mizrachi, E.5
Permutt, M.A.6
-
44
-
-
21044453408
-
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes
-
Jaeschke A, Rincon M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ: Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad SciUSA102:6931-6935, 2005
-
(2005)
Proc Natl Acad SciUSA
, vol.102
, pp. 6931-6935
-
-
Jaeschke, A.1
Rincon, M.2
Doran, B.3
Reilly, J.4
Neuberg, D.5
Greiner, D.L.6
Shultz, L.D.7
Rossini, A.A.8
Flavell, R.A.9
Davis, R.J.10
-
45
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
Delepine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C: EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 25:406-409, 2000
-
(2000)
Nat Genet
, vol.25
, pp. 406-409
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
46
-
-
0031941010
-
Transcription factors C/EBP alpha, C/EBP beta, and CHOP (Gadd153) expressed during the differentiation program of keratinocytes in vitro and in vivo
-
Maytin EV, Habener JF: Transcription factors C/EBP alpha, C/EBP beta, and CHOP (Gadd153) expressed during the differentiation program of keratinocytes in vitro and in vivo. J Invest Dermatol 110:238-246, 1998
-
(1998)
J Invest Dermatol
, vol.110
, pp. 238-246
-
-
Maytin, E.V.1
Habener, J.F.2
-
47
-
-
0033562601
-
Regulated expression and functional role of the transcription factor CHOP (GADD153) in erythroid growth and differentiation
-
Coutts M, Cui K, Davis KL, Keutzer JC, Sytkowski AJ: Regulated expression and functional role of the transcription factor CHOP (GADD153) in erythroid growth and differentiation. Blood 93:3369-3378, 1999
-
(1999)
Blood
, vol.93
, pp. 3369-3378
-
-
Coutts, M.1
Cui, K.2
Davis, K.L.3
Keutzer, J.C.4
Sytkowski, A.J.5
-
48
-
-
35848963392
-
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
-
Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M: The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia 50:2486-2494, 2007
-
(2007)
Diabetologia
, vol.50
, pp. 2486-2494
-
-
Marchetti, P.1
Bugliani, M.2
Lupi, R.3
Marselli, L.4
Masini, M.5
Boggi, U.6
Filipponi, F.7
Weir, G.C.8
Eizirik, D.L.9
Cnop, M.10
|