Structure, mechanism and inhibition of γ-secretase and presenilin-like proteases

Biological Chemistry

Volumn 391, Issue 8, 2010, Pages 839-847

  Wolfe, Michael S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Amyloid; Notch receptor; Peptidomimetics; Signal peptide peptidase; Substrate analogs; Substrate recognition

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NOTCH RECEPTOR; PRESENILIN; PROTEINASE; SIGNAL PEPTIDE PEPTIDASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; CONFERENCE PAPER; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYMOLOGY; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; HUMANS; PRESENILINS; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

EID: 77955944764     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.086     Document Type: Conference Paper

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