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Volumn 2, Issue 7, 2000, Pages 463-465
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Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1
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Author keywords
[No Author keywords available]
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Indexed keywords
AMYLOID PRECURSOR PROTEIN;
GAMMA SECRETASE;
NOTCH RECEPTOR;
PRESENILIN 1;
PRESENILIN 2;
ALZHEIMER DISEASE;
ANIMAL CELL;
ARTICLE;
EMBRYO;
MOUSE;
MUTATION;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN DEGRADATION;
PROTEIN METABOLISM;
PROTEIN PROCESSING;
SIGNAL TRANSDUCTION;
AMYLOID BETA-PROTEIN;
AMYLOID BETA-PROTEIN PRECURSOR;
AMYLOID PRECURSOR PROTEIN SECRETASES;
ANIMALS;
ASPARTIC ENDOPEPTIDASES;
CELLS, CULTURED;
ENDOPEPTIDASES;
GENE DELETION;
MEMBRANE PROTEINS;
MICE;
MICE, KNOCKOUT;
PEPTIDE FRAGMENTS;
PRESENILIN-1;
PRESENILIN-2;
PROTEIN PROCESSING, POST-TRANSLATIONAL;
PROTEIN STRUCTURE, TERTIARY;
RECEPTOR, NOTCH1;
RECEPTORS, CELL SURFACE;
TRANSCRIPTION FACTORS;
TRANSFECTION;
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EID: 0033779635
PISSN: 14657392
EISSN: None
Source Type: Journal
DOI: 10.1038/35017108 Document Type: Article |
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Times cited : (377)
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References (21)
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