Designed helical peptides inhibit an intramembrane protease

Journal of the American Chemical Society

Volumn 125, Issue 39, 2003, Pages 11794-11795

  Das, Chittaranjan ^a   Berezovska, Oksana ^b   Diehl, Thekla S ^a   Genet, Cedric ^a   Buldyrev, Ilya ^a   Tsai, Jui Yi ^a   Hyman, Bradley T ^b   Wolfe, Michael S ^a  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; GAMMA SECRETASE; PROTEINASE;

ALPHA HELIX; ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME INHIBITION; LIPID BILAYER; MEMBRANE BINDING; PEPTIDE SYNTHESIS; SEQUENCE HOMOLOGY; SOLUBILIZATION;

AMINOISOBUTYRIC ACIDS; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; BINDING SITES; DRUG DESIGN; ENDOPEPTIDASES; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY; STEREOISOMERISM;

EID: 0141509025     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja037131v     Document Type: Article

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