-
1
-
-
4143070533
-
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
-
Ahn S., Shenoy S.K., Wei H., and Lefkowitz R.J. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J. Biol. Chem. 279 (2004) 35518-35525
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35518-35525
-
-
Ahn, S.1
Shenoy, S.K.2
Wei, H.3
Lefkowitz, R.J.4
-
2
-
-
67649797371
-
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
-
Ahn S., Kim J., Hara M.R., Ren X.R., and Lefkowitz R.J. {beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. J. Biol. Chem. 284 (2009) 8855-8865
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8855-8865
-
-
Ahn, S.1
Kim, J.2
Hara, M.R.3
Ren, X.R.4
Lefkowitz, R.J.5
-
3
-
-
14844338481
-
beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
-
Barnes W.G., Reiter E., Violin J.D., Ren X.R., Milligan G., and Lefkowitz R.J. beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J. Biol. Chem. 280 (2005) 8041-8050
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8041-8050
-
-
Barnes, W.G.1
Reiter, E.2
Violin, J.D.3
Ren, X.R.4
Milligan, G.5
Lefkowitz, R.J.6
-
4
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu J.M., Sotnikova T.D., Yao W.D., Kockeritz L., Woodgett J.R., Gainetdinov R.R., and Caron M.G. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. USA 101 (2004) 5099-5104
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
Kockeritz, L.4
Woodgett, J.R.5
Gainetdinov, R.R.6
Caron, M.G.7
-
5
-
-
22744449073
-
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
-
Beaulieu J.M., Sotnikova T.D., Marion S., Lefkowitz R.J., Gainetdinov R.R., and Caron M.G. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122 (2005) 261-273
-
(2005)
Cell
, vol.122
, pp. 261-273
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Marion, S.3
Lefkowitz, R.J.4
Gainetdinov, R.R.5
Caron, M.G.6
-
6
-
-
37649023273
-
A beta-arrestin 2 signaling complex mediates lithium action on behavior
-
Beaulieu J.M., Marion S., Rodriguiz R.M., Medvedev I.O., Sotnikova T.D., Ghisi V., Wetsel W.C., Lefkowitz R.J., Gainetdinov R.R., and Caron M.G. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell 132 (2008) 125-136
-
(2008)
Cell
, vol.132
, pp. 125-136
-
-
Beaulieu, J.M.1
Marion, S.2
Rodriguiz, R.M.3
Medvedev, I.O.4
Sotnikova, T.D.5
Ghisi, V.6
Wetsel, W.C.7
Lefkowitz, R.J.8
Gainetdinov, R.R.9
Caron, M.G.10
-
7
-
-
67649556158
-
The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization
-
Berthouze M., Venkataramanan V., Li Y., and Shenoy S.K. The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization. EMBO J. 28 (2009) 1684-1696
-
(2009)
EMBO J.
, vol.28
, pp. 1684-1696
-
-
Berthouze, M.1
Venkataramanan, V.2
Li, Y.3
Shenoy, S.K.4
-
8
-
-
37549035071
-
Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4
-
Bhandari D., Trejo J., Benovic J.L., and Marchese A. Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. J. Biol. Chem. 282 (2007) 36971-36979
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36971-36979
-
-
Bhandari, D.1
Trejo, J.2
Benovic, J.L.3
Marchese, A.4
-
9
-
-
0033601341
-
Enhanced morphine analgesia in mice lacking beta-arrestin 2
-
Bohn L.M., Lefkowitz R.J., Gainetdinov R.R., Peppel K., Caron M.G., and Lin F.T. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science 286 (1999) 2495-2498
-
(1999)
Science
, vol.286
, pp. 2495-2498
-
-
Bohn, L.M.1
Lefkowitz, R.J.2
Gainetdinov, R.R.3
Peppel, K.4
Caron, M.G.5
Lin, F.T.6
-
10
-
-
0034619796
-
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
-
Bohn L.M., Gainetdinov R.R., Lin F.T., Lefkowitz R.J., and Caron M.G. Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 408 (2000) 720-723
-
(2000)
Nature
, vol.408
, pp. 720-723
-
-
Bohn, L.M.1
Gainetdinov, R.R.2
Lin, F.T.3
Lefkowitz, R.J.4
Caron, M.G.5
-
11
-
-
40849088096
-
MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation
-
Bondi C.D., McKeon R.M., Bennett J.M., Ignatius P.F., Brydon L., Jockers R., Melan M.A., and Witt-Enderby P.A. MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation. J. Pineal Res. 44 (2008) 288-298
-
(2008)
J. Pineal Res.
, vol.44
, pp. 288-298
-
-
Bondi, C.D.1
McKeon, R.M.2
Bennett, J.M.3
Ignatius, P.F.4
Brydon, L.5
Jockers, R.6
Melan, M.A.7
Witt-Enderby, P.A.8
-
12
-
-
33745832645
-
Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes
-
Bruchas M.R., Macey T.A., Lowe J.D., and Chavkin C. Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes. J. Biol. Chem. 281 (2006) 18081-18089
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 18081-18089
-
-
Bruchas, M.R.1
Macey, T.A.2
Lowe, J.D.3
Chavkin, C.4
-
13
-
-
34249856025
-
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo
-
Bryja V., Gradl D., Schambony A., Arenas E., and Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc. Natl. Acad. Sci. USA 104 (2007) 6690-6695
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6690-6695
-
-
Bryja, V.1
Gradl, D.2
Schambony, A.3
Arenas, E.4
Schulte, G.5
-
14
-
-
57049149000
-
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways
-
Bryja V., Schambony A., Cajanek L., Dominguez I., Arenas E., and Schulte G. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep. 9 (2008) 1244-1250
-
(2008)
EMBO Rep.
, vol.9
, pp. 1244-1250
-
-
Bryja, V.1
Schambony, A.2
Cajanek, L.3
Dominguez, I.4
Arenas, E.5
Schulte, G.6
-
15
-
-
31944452649
-
Role of beta-arrestin 1 in the metastatic progression of colorectal cancer
-
Buchanan F.G., Gorden D.L., Matta P., Shi Q., Matrisian L.M., and DuBois R.N. Role of beta-arrestin 1 in the metastatic progression of colorectal cancer. Proc. Natl. Acad. Sci. USA 103 (2006) 1492-1497
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1492-1497
-
-
Buchanan, F.G.1
Gorden, D.L.2
Matta, P.3
Shi, Q.4
Matrisian, L.M.5
DuBois, R.N.6
-
16
-
-
34548487757
-
Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: role of G-proteins and beta-arrestins
-
Camina J.P., Lodeiro M., Ischenko O., Martini A.C., and Casanueva F.F. Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: role of G-proteins and beta-arrestins. J. Cell. Physiol. 213 (2007) 187-200
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 187-200
-
-
Camina, J.P.1
Lodeiro, M.2
Ischenko, O.3
Martini, A.C.4
Casanueva, F.F.5
-
17
-
-
4243144134
-
Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization
-
Cano D.A., Murcia N.S., Pazour G.J., and Hebrok M. Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development 131 (2004) 3457-3467
-
(2004)
Development
, vol.131
, pp. 3457-3467
-
-
Cano, D.A.1
Murcia, N.S.2
Pazour, G.J.3
Hebrok, M.4
-
18
-
-
33646345370
-
Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization
-
Caunt C.J., Finch A.R., Sedgley K.R., Oakley L., Luttrell L.M., and McArdle C.A. Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization. J. Biol. Chem. 281 (2006) 2701-2710
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2701-2710
-
-
Caunt, C.J.1
Finch, A.R.2
Sedgley, K.R.3
Oakley, L.4
Luttrell, L.M.5
McArdle, C.A.6
-
19
-
-
33845316454
-
The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling
-
Charest P.G., Oligny-Longpre G., Bonin H., Azzi M., and Bouvier M. The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling. Cell. Signal. 19 (2007) 32-41
-
(2007)
Cell. Signal.
, vol.19
, pp. 32-41
-
-
Charest, P.G.1
Oligny-Longpre, G.2
Bonin, H.3
Azzi, M.4
Bouvier, M.5
-
20
-
-
0035909783
-
beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
-
Chen W., Hu L.A., Semenov M.V., Yanagawa S., Kikuchi A., Lefkowitz R.J., and Miller W.E. beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins. Proc. Natl. Acad. Sci. USA 98 (2001) 14889-14894
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14889-14894
-
-
Chen, W.1
Hu, L.A.2
Semenov, M.V.3
Yanagawa, S.4
Kikuchi, A.5
Lefkowitz, R.J.6
Miller, W.E.7
-
21
-
-
0042471943
-
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
-
Chen W., Kirkbride K.C., How T., Nelson C.D., Mo J., Frederick J.P., Wang X.F., Lefkowitz R.J., and Blobe G.C. Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling. Science 301 (2003) 1394-1397
-
(2003)
Science
, vol.301
, pp. 1394-1397
-
-
Chen, W.1
Kirkbride, K.C.2
How, T.3
Nelson, C.D.4
Mo, J.5
Frederick, J.P.6
Wang, X.F.7
Lefkowitz, R.J.8
Blobe, G.C.9
-
22
-
-
0041470133
-
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
-
Chen W., ten Berge D., Brown J., Ahn S., Hu L.A., Miller W.E., Caron M.G., Barak L.S., Nusse R., and Lefkowitz R.J. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 301 (2003) 1391-1394
-
(2003)
Science
, vol.301
, pp. 1391-1394
-
-
Chen, W.1
ten Berge, D.2
Brown, J.3
Ahn, S.4
Hu, L.A.5
Miller, W.E.6
Caron, M.G.7
Barak, L.S.8
Nusse, R.9
Lefkowitz, R.J.10
-
23
-
-
11144256194
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
-
Chen W., Ren X.R., Nelson C.D., Barak L.S., Chen J.K., Beachy P.A., de Sauvage F., and Lefkowitz R.J. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science 306 (2004) 2257-2260
-
(2004)
Science
, vol.306
, pp. 2257-2260
-
-
Chen, W.1
Ren, X.R.2
Nelson, C.D.3
Barak, L.S.4
Chen, J.K.5
Beachy, P.A.6
de Sauvage, F.7
Lefkowitz, R.J.8
-
24
-
-
58649089130
-
Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades
-
Chen J., Rusnak M., Lombroso P.J., and Sidhu A. Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. Eur. J. Neurosci. 29 (2009) 287-306
-
(2009)
Eur. J. Neurosci.
, vol.29
, pp. 287-306
-
-
Chen, J.1
Rusnak, M.2
Lombroso, P.J.3
Sidhu, A.4
-
25
-
-
69249245332
-
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
-
Chen M.H., Wilson C.W., Li Y.J., Law K.K., Lu C.S., Gacayan R., Zhang X., Hui C.C., and Chuang P.T. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev. 23 (2009) 1910-1928
-
(2009)
Genes Dev.
, vol.23
, pp. 1910-1928
-
-
Chen, M.H.1
Wilson, C.W.2
Li, Y.J.3
Law, K.K.4
Lu, C.S.5
Gacayan, R.6
Zhang, X.7
Hui, C.C.8
Chuang, P.T.9
-
26
-
-
56749110996
-
The type 1 insulin-like growth factor receptor pathway
-
Chitnis M.M., Yuen J.S., Protheroe A.S., Pollak M., and Macaulay V.M. The type 1 insulin-like growth factor receptor pathway. Clin. Cancer Res. 14 (2008) 6364-6370
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6364-6370
-
-
Chitnis, M.M.1
Yuen, J.S.2
Protheroe, A.S.3
Pollak, M.4
Macaulay, V.M.5
-
27
-
-
58149343374
-
The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair
-
Christensen S.T., Pedersen S.F., Satir P., Veland I.R., and Schneider L. The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair. Curr. Top. Dev. Biol. 85 (2008) 261-301
-
(2008)
Curr. Top. Dev. Biol.
, vol.85
, pp. 261-301
-
-
Christensen, S.T.1
Pedersen, S.F.2
Satir, P.3
Veland, I.R.4
Schneider, L.5
-
28
-
-
38849094724
-
Structure of Vps26B and mapping of its interaction with the retromer protein complex
-
Collins B.M., Norwood S.J., Kerr M.C., Mahony D., Seaman M.N., Teasdale R.D., and Owen D.J. Structure of Vps26B and mapping of its interaction with the retromer protein complex. Traffic 9 (2008) 366-379
-
(2008)
Traffic
, vol.9
, pp. 366-379
-
-
Collins, B.M.1
Norwood, S.J.2
Kerr, M.C.3
Mahony, D.4
Seaman, M.N.5
Teasdale, R.D.6
Owen, D.J.7
-
29
-
-
0030732503
-
beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation
-
Conner D.A., Mathier M.A., Mortensen R.M., Christe M., Vatner S.F., Seidman C.E., and Seidman J.G. beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation. Circ. Res. 81 (1997) 1021-1026
-
(1997)
Circ. Res.
, vol.81
, pp. 1021-1026
-
-
Conner, D.A.1
Mathier, M.A.2
Mortensen, R.M.3
Christe, M.4
Vatner, S.F.5
Seidman, C.E.6
Seidman, J.G.7
-
30
-
-
26644460824
-
Vertebrate Smoothened functions at the primary cilium
-
Corbit K.C., Aanstad P., Singla V., Norman A.R., Stainier D.Y., and Reiter J.F. Vertebrate Smoothened functions at the primary cilium. Nature 437 (2005) 1018-1021
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
31
-
-
37749054886
-
Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
-
Corbit K.C., Shyer A.E., Dowdle W.E., Gaulden J., Singla V., Chen M.H., Chuang P.T., and Reiter J.F. Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat. Cell Biol. 10 (2008) 70-76
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 70-76
-
-
Corbit, K.C.1
Shyer, A.E.2
Dowdle, W.E.3
Gaulden, J.4
Singla, V.5
Chen, M.H.6
Chuang, P.T.7
Reiter, J.F.8
-
32
-
-
0035844282
-
Insulin and insulin-like growth factor I receptors utilize different G protein signaling components
-
Dalle S., Ricketts W., Imamura T., Vollenweider P., and Olefsky J.M. Insulin and insulin-like growth factor I receptors utilize different G protein signaling components. J. Biol. Chem. 276 (2001) 15688-15695
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15688-15695
-
-
Dalle, S.1
Ricketts, W.2
Imamura, T.3
Vollenweider, P.4
Olefsky, J.M.5
-
33
-
-
0036333651
-
Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1
-
Dalle S., Imamura T., Rose D.W., Worrall D.S., Ugi S., Hupfeld C.J., and Olefsky J.M. Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1. Mol. Cell. Biol. 22 (2002) 6272-6285
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6272-6285
-
-
Dalle, S.1
Imamura, T.2
Rose, D.W.3
Worrall, D.S.4
Ugi, S.5
Hupfeld, C.J.6
Olefsky, J.M.7
-
34
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis R.J. Signal transduction by the JNK group of MAP kinases. Cell 103 (2000) 239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
35
-
-
40349108549
-
Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction
-
Defea K. Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction. Br. J. Pharmacol. 153 Suppl 1 (2008) S298-S309
-
(2008)
Br. J. Pharmacol.
, vol.153
, Issue.SUPPL. 1
-
-
Defea, K.1
-
36
-
-
0034689003
-
beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea K.A., Zalevsky J., Thoma M.S., Dery O., Mullins R.D., and Bunnett N.W. beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J. Cell Biol. 148 (2000) 1267-1281
-
(2000)
J. Cell Biol.
, vol.148
, pp. 1267-1281
-
-
DeFea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Dery, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
38
-
-
44849117014
-
Beta-arrestin-mediated signaling regulates protein synthesis
-
DeWire S.M., Kim J., Whalen E.J., Ahn S., Chen M., and Lefkowitz R.J. Beta-arrestin-mediated signaling regulates protein synthesis. J. Biol. Chem. 283 (2008) 10611-10620
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10611-10620
-
-
DeWire, S.M.1
Kim, J.2
Whalen, E.J.3
Ahn, S.4
Chen, M.5
Lefkowitz, R.J.6
-
39
-
-
2342592708
-
IGF type 1 receptor: a cell cycle progression factor that regulates aging
-
Dupont J., and Holzenberger M. IGF type 1 receptor: a cell cycle progression factor that regulates aging. Cell Cycle 2 (2003) 270-272
-
(2003)
Cell Cycle
, vol.2
, pp. 270-272
-
-
Dupont, J.1
Holzenberger, M.2
-
41
-
-
23044466047
-
Specificity and versatility in tgf-beta signaling through Smads
-
Feng X.H., and Derynck R. Specificity and versatility in tgf-beta signaling through Smads. Annu. Rev. Cell Dev. Biol. 21 (2005) 659-693
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
42
-
-
58049195151
-
Endocytosis of the type III transforming growth factor-beta (TGF-beta) receptor through the clathrin-independent/lipid raft pathway regulates TGF-beta signaling and receptor down-regulation
-
Finger E.C., Lee N.Y., You H.J., and Blobe G.C. Endocytosis of the type III transforming growth factor-beta (TGF-beta) receptor through the clathrin-independent/lipid raft pathway regulates TGF-beta signaling and receptor down-regulation. J. Biol. Chem. 283 (2008) 34808-34818
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34808-34818
-
-
Finger, E.C.1
Lee, N.Y.2
You, H.J.3
Blobe, G.C.4
-
43
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
-
Gao H., Sun Y., Wu Y., Luan B., Wang Y., Qu B., and Pei G. Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol. Cell 14 (2004) 303-317
-
(2004)
Mol. Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
Pei, G.7
-
44
-
-
0141483377
-
A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis
-
Ge L., Ly Y., Hollenberg M., and DeFea K. A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis. J. Biol. Chem. 278 (2003) 34418-34426
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34418-34426
-
-
Ge, L.1
Ly, Y.2
Hollenberg, M.3
DeFea, K.4
-
45
-
-
30344479947
-
A Drosophila nonvisual arrestin is required for the maintenance of olfactory sensitivity
-
Ge H., Krishnan P., Liu L., Krishnan B., Davis R.L., Hardin P.E., and Roman G. A Drosophila nonvisual arrestin is required for the maintenance of olfactory sensitivity. Chem. Senses 31 (2006) 49-62
-
(2006)
Chem. Senses
, vol.31
, pp. 49-62
-
-
Ge, H.1
Krishnan, P.2
Liu, L.3
Krishnan, B.4
Davis, R.L.5
Hardin, P.E.6
Roman, G.7
-
46
-
-
33744957160
-
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
-
Gesty-Palmer D., Chen M., Reiter E., Ahn S., Nelson C.D., Wang S., Eckhardt A.E., Cowan C.L., Spurney R.F., Luttrell L.M., and Lefkowitz R.J. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J. Biol. Chem. 281 (2006) 10856-10864
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 10856-10864
-
-
Gesty-Palmer, D.1
Chen, M.2
Reiter, E.3
Ahn, S.4
Nelson, C.D.5
Wang, S.6
Eckhardt, A.E.7
Cowan, C.L.8
Spurney, R.F.9
Luttrell, L.M.10
Lefkowitz, R.J.11
-
47
-
-
21644463635
-
{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase
-
Girnita L., Shenoy S.K., Sehat B., Vasilcanu R., Girnita A., Lefkowitz R.J., and Larsson O. {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. J. Biol. Chem. 280 (2005) 24412-24419
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 24412-24419
-
-
Girnita, L.1
Shenoy, S.K.2
Sehat, B.3
Vasilcanu, R.4
Girnita, A.5
Lefkowitz, R.J.6
Larsson, O.7
-
48
-
-
34249705229
-
Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression
-
Girnita L., Shenoy S.K., Sehat B., Vasilcanu R., Vasilcanu D., Girnita A., Lefkowitz R.J., and Larsson O. Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression. J. Biol. Chem. 282 (2007) 11329-11338
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11329-11338
-
-
Girnita, L.1
Shenoy, S.K.2
Sehat, B.3
Vasilcanu, R.4
Vasilcanu, D.5
Girnita, A.6
Lefkowitz, R.J.7
Larsson, O.8
-
49
-
-
0037166254
-
alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression
-
Goel R., Phillips-Mason P.J., Raben D.M., and Baldassare J.J. alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression. J. Biol. Chem. 277 (2002) 18640-18648
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18640-18648
-
-
Goel, R.1
Phillips-Mason, P.J.2
Raben, D.M.3
Baldassare, J.J.4
-
50
-
-
57649186957
-
A novel protein kinase A-independent, beta-arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta2-adrenergic receptors
-
Gong K., Li Z., Xu M., Du J., Lv Z., and Zhang Y. A novel protein kinase A-independent, beta-arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta2-adrenergic receptors. J. Biol. Chem. 283 (2008) 29028-29036
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29028-29036
-
-
Gong, K.1
Li, Z.2
Xu, M.3
Du, J.4
Lv, Z.5
Zhang, Y.6
-
51
-
-
40849133772
-
Role of transforming growth factor-beta superfamily signaling pathways in human disease
-
Gordon K.J., and Blobe G.C. Role of transforming growth factor-beta superfamily signaling pathways in human disease. Biochim. Biophys. Acta 1782 (2008) 197-228
-
(2008)
Biochim. Biophys. Acta
, vol.1782
, pp. 197-228
-
-
Gordon, K.J.1
Blobe, G.C.2
-
52
-
-
33845870964
-
Arrestins: ubiquitous regulators of cellular signaling pathways
-
Gurevich E.V., and Gurevich V.V. Arrestins: ubiquitous regulators of cellular signaling pathways. Genome Biol. 7 (2006) 236
-
(2006)
Genome Biol.
, vol.7
, pp. 236
-
-
Gurevich, E.V.1
Gurevich, V.V.2
-
53
-
-
0032519906
-
The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling
-
Hammerschmidt M., and McMahon A.P. The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling. Dev. Biol. 194 (1998) 166-171
-
(1998)
Dev. Biol.
, vol.194
, pp. 166-171
-
-
Hammerschmidt, M.1
McMahon, A.P.2
-
54
-
-
0344308346
-
Notch signaling in development and disease
-
Harper J.A., Yuan J.S., Tan J.B., Visan I., and Guidos C.J. Notch signaling in development and disease. Clin. Genet. 64 (2003) 461-472
-
(2003)
Clin. Genet.
, vol.64
, pp. 461-472
-
-
Harper, J.A.1
Yuan, J.S.2
Tan, J.B.3
Visan, I.4
Guidos, C.J.5
-
55
-
-
0033754604
-
Stirring up development with the heterotrimeric kinesin KIF3
-
Hirokawa N. Stirring up development with the heterotrimeric kinesin KIF3. Traffic 1 (2000) 29-34
-
(2000)
Traffic
, vol.1
, pp. 29-34
-
-
Hirokawa, N.1
-
56
-
-
57649213524
-
Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2
-
Hoffmann C., Ziegler N., Reiner S., Krasel C., and Lohse M.J. Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2. J. Biol. Chem. 283 (2008) 30933-30941
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30933-30941
-
-
Hoffmann, C.1
Ziegler, N.2
Reiner, S.3
Krasel, C.4
Lohse, M.J.5
-
57
-
-
70349986352
-
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia
-
Huang P., and Schier A.F. Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development 136 (2009) 3089-3098
-
(2009)
Development
, vol.136
, pp. 3089-3098
-
-
Huang, P.1
Schier, A.F.2
-
58
-
-
23844485210
-
Cilia and Hedgehog responsiveness in the mouse
-
Huangfu D., and Anderson K.V. Cilia and Hedgehog responsiveness in the mouse. Proc. Natl. Acad. Sci. USA 102 (2005) 11325-11330
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11325-11330
-
-
Huangfu, D.1
Anderson, K.V.2
-
59
-
-
31644442906
-
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
-
Huangfu D., and Anderson K.V. Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development 133 (2006) 3-14
-
(2006)
Development
, vol.133
, pp. 3-14
-
-
Huangfu, D.1
Anderson, K.V.2
-
60
-
-
0242581681
-
Hedgehog signalling in the mouse requires intraflagellar transport proteins
-
Huangfu D., Liu A., Rakeman A.S., Murcia N.S., Niswander L., and Anderson K.V. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426 (2003) 83-87
-
(2003)
Nature
, vol.426
, pp. 83-87
-
-
Huangfu, D.1
Liu, A.2
Rakeman, A.S.3
Murcia, N.S.4
Niswander, L.5
Anderson, K.V.6
-
61
-
-
15744390934
-
Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis
-
Hunton D.L., Barnes W.G., Kim J., Ren X.R., Violin J.D., Reiter E., Milligan G., Patel D.D., and Lefkowitz R.J. Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis. Mol. Pharmacol. 67 (2005) 1229-1236
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1229-1236
-
-
Hunton, D.L.1
Barnes, W.G.2
Kim, J.3
Ren, X.R.4
Violin, J.D.5
Reiter, E.6
Milligan, G.7
Patel, D.D.8
Lefkowitz, R.J.9
-
62
-
-
12544254298
-
Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors
-
Hupfeld C.J., Resnik J.L., Ugi S., and Olefsky J.M. Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors. J. Biol. Chem. 280 (2005) 1016-1023
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1016-1023
-
-
Hupfeld, C.J.1
Resnik, J.L.2
Ugi, S.3
Olefsky, J.M.4
-
63
-
-
0036319160
-
Regulation of lysophosphatidic acid receptor-stimulated response by G-protein-coupled receptor kinase-2 and beta-arrestin1 in FRTL-5 rat thyroid cells
-
Iacovelli L., Capobianco L., D'Ancona G.M., Picascia A., and De Blasi A. Regulation of lysophosphatidic acid receptor-stimulated response by G-protein-coupled receptor kinase-2 and beta-arrestin1 in FRTL-5 rat thyroid cells. J. Endocrinol. 174 (2002) 103-110
-
(2002)
J. Endocrinol.
, vol.174
, pp. 103-110
-
-
Iacovelli, L.1
Capobianco, L.2
D'Ancona, G.M.3
Picascia, A.4
De Blasi, A.5
-
64
-
-
0035577854
-
Hedgehog signaling in animal development: paradigms and principles
-
Ingham P.W., and McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15 (2001) 3059-3087
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
65
-
-
33646713486
-
The TGF beta activated kinase TAK1 regulates vascular development in vivo
-
Jadrich J.L., O'Connor M.B., and Coucouvanis E. The TGF beta activated kinase TAK1 regulates vascular development in vivo. Development 133 (2006) 1529-1541
-
(2006)
Development
, vol.133
, pp. 1529-1541
-
-
Jadrich, J.L.1
O'Connor, M.B.2
Coucouvanis, E.3
-
66
-
-
33646446045
-
Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism
-
Jiang Q., Yan Z., and Feng J. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J. Neurosci. 26 (2006) 4318-4328
-
(2006)
J. Neurosci.
, vol.26
, pp. 4318-4328
-
-
Jiang, Q.1
Yan, Z.2
Feng, J.3
-
67
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang J., and Hui C.C. Hedgehog signaling in development and cancer. Dev. Cell 15 (2008) 801-812
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
68
-
-
55749108844
-
Functional characterization of kurtz, a Drosophila non-visual arrestin, reveals conservation of GPCR desensitization mechanisms
-
Johnson E.C., Tift F.W., McCauley A., Liu L., and Roman G. Functional characterization of kurtz, a Drosophila non-visual arrestin, reveals conservation of GPCR desensitization mechanisms. Insect Biochem. Mol. Biol. 38 (2008) 1016-1022
-
(2008)
Insect Biochem. Mol. Biol.
, vol.38
, pp. 1016-1022
-
-
Johnson, E.C.1
Tift, F.W.2
McCauley, A.3
Liu, L.4
Roman, G.5
-
69
-
-
28344452845
-
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
-
Kang J., Shi Y., Xiang B., Qu B., Su W., Zhu M., Zhang M., Bao G., Wang F., Zhang X., et al. A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell 123 (2005) 833-847
-
(2005)
Cell
, vol.123
, pp. 833-847
-
-
Kang, J.1
Shi, Y.2
Xiang, B.3
Qu, B.4
Su, W.5
Zhu, M.6
Zhang, M.7
Bao, G.8
Wang, F.9
Zhang, X.10
-
70
-
-
33751509646
-
A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation
-
Kara E., Crepieux P., Gauthier C., Martinat N., Piketty V., Guillou F., and Reiter E. A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation. Mol. Endocrinol. 20 (2006) 3014-3026
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 3014-3026
-
-
Kara, E.1
Crepieux, P.2
Gauthier, C.3
Martinat, N.4
Piketty, V.5
Guillou, F.6
Reiter, E.7
-
71
-
-
11844299003
-
Trimeric G protein-dependent frizzled signaling in Drosophila
-
Katanaev V.L., Ponzielli R., Semeriva M., and Tomlinson A. Trimeric G protein-dependent frizzled signaling in Drosophila. Cell 120 (2005) 111-122
-
(2005)
Cell
, vol.120
, pp. 111-122
-
-
Katanaev, V.L.1
Ponzielli, R.2
Semeriva, M.3
Tomlinson, A.4
-
72
-
-
34948906833
-
Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/Akt signal
-
Kawasaki A., Torii K., Yamashita Y., Nishizawa K., Kanekura K., Katada M., Ito M., Nishimoto I., Terashita K., Aiso S., and Matsuoka M. Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/Akt signal. Cell. Signal. 19 (2007) 2498-2506
-
(2007)
Cell. Signal.
, vol.19
, pp. 2498-2506
-
-
Kawasaki, A.1
Torii, K.2
Yamashita, Y.3
Nishizawa, K.4
Kanekura, K.5
Katada, M.6
Ito, M.7
Nishimoto, I.8
Terashita, K.9
Aiso, S.10
Matsuoka, M.11
-
73
-
-
34248995559
-
Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements
-
Kim G.H., and Han J.K. Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J. 26 (2007) 2513-2526
-
(2007)
EMBO J.
, vol.26
, pp. 2513-2526
-
-
Kim, G.H.1
Han, J.K.2
-
74
-
-
4444347661
-
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells
-
Kim S.E., Cho J.Y., Kim K.S., Lee S.J., Lee K.H., and Choi K.Y. Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells. Cell. Signal. 16 (2004) 1309-1317
-
(2004)
Cell. Signal.
, vol.16
, pp. 1309-1317
-
-
Kim, S.E.1
Cho, J.Y.2
Kim, K.S.3
Lee, S.J.4
Lee, K.H.5
Choi, K.Y.6
-
75
-
-
52249098269
-
Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements
-
Kim G.H., Her J.H., and Han J.K. Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. J. Cell Biol. 182 (2008) 1073-1082
-
(2008)
J. Cell Biol.
, vol.182
, pp. 1073-1082
-
-
Kim, G.H.1
Her, J.H.2
Han, J.K.3
-
76
-
-
55749084393
-
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation
-
Kim I.M., Tilley D.G., Chen J., Salazar N.C., Whalen E.J., Violin J.D., and Rockman H.A. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proc. Natl. Acad. Sci. USA 105 (2008) 14555-14560
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14555-14560
-
-
Kim, I.M.1
Tilley, D.G.2
Chen, J.3
Salazar, N.C.4
Whalen, E.J.5
Violin, J.D.6
Rockman, H.A.7
-
77
-
-
66449134043
-
Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor
-
Kim J., Ahn S., Rajagopal K., and Lefkowitz R.J. Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor. J. Biol. Chem. 284 (2009) 11953-11962
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11953-11962
-
-
Kim, J.1
Ahn, S.2
Rajagopal, K.3
Lefkowitz, R.J.4
-
78
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA 93 (1996) 8455-8459
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
79
-
-
24644499046
-
Wnt and calcium signaling: beta-catenin-independent pathways
-
Kohn A.D., and Moon R.T. Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium 38 (2005) 439-446
-
(2005)
Cell Calcium
, vol.38
, pp. 439-446
-
-
Kohn, A.D.1
Moon, R.T.2
-
80
-
-
0037223063
-
Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization
-
Kohout T.A., and Lefkowitz R.J. Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol. Pharmacol. 63 (2003) 9-18
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 9-18
-
-
Kohout, T.A.1
Lefkowitz, R.J.2
-
81
-
-
64249172203
-
The canonical Notch signaling pathway: unfolding the activation mechanism
-
Kopan R., and Ilagan M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137 (2009) 216-233
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
82
-
-
46449127054
-
Beta-arrestin-mediated localization of smoothened to the primary cilium
-
Kovacs J.J., Whalen E.J., Liu R., Xiao K., Kim J., Chen M., Wang J., Chen W., and Lefkowitz R.J. Beta-arrestin-mediated localization of smoothened to the primary cilium. Science 320 (2008) 1777-1781
-
(2008)
Science
, vol.320
, pp. 1777-1781
-
-
Kovacs, J.J.1
Whalen, E.J.2
Liu, R.3
Xiao, K.4
Kim, J.5
Chen, M.6
Wang, J.7
Chen, W.8
Lefkowitz, R.J.9
-
83
-
-
58149306364
-
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling
-
Labasque M., Reiter E., Becamel C., Bockaert J., and Marin P. Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling. Mol. Biol. Cell 19 (2008) 4640-4650
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4640-4650
-
-
Labasque, M.1
Reiter, E.2
Becamel, C.3
Bockaert, J.4
Marin, P.5
-
84
-
-
67249152481
-
Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer
-
Lakshmikanthan V., Zou L., Kim J.I., Michal A., Nie Z., Messias N.C., Benovic J.L., and Daaka Y. Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer. Proc. Natl. Acad. Sci. USA 106 (2009) 9379-9384
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9379-9384
-
-
Lakshmikanthan, V.1
Zou, L.2
Kim, J.I.3
Michal, A.4
Nie, Z.5
Messias, N.C.6
Benovic, J.L.7
Daaka, Y.8
-
86
-
-
34547111838
-
The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells
-
Lee N.Y., and Blobe G.C. The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells. J. Biol. Chem. 282 (2007) 21507-21517
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 21507-21517
-
-
Lee, N.Y.1
Blobe, G.C.2
-
87
-
-
70350088248
-
The TGF-{beta} Type III Receptor Mediates Distinct Subcellular Trafficking and Downstream Signaling of ALK3 and ALK6 Receptors
-
10.1091/mbc.E1009-1007-0539 in press
-
Lee N.Y., Kirkbride K.C., Sheu R.D., and Blobe G.C. The TGF-{beta} Type III Receptor Mediates Distinct Subcellular Trafficking and Downstream Signaling of ALK3 and ALK6 Receptors. Mol. Biol. Cell (2009) 10.1091/mbc.E1009-1007-0539 in press
-
(2009)
Mol. Biol. Cell
-
-
Lee, N.Y.1
Kirkbride, K.C.2
Sheu, R.D.3
Blobe, G.C.4
-
88
-
-
2942618584
-
beta-arrestins: traffic cops of cell signaling
-
Lefkowitz R.J., and Whalen E.J. beta-arrestins: traffic cops of cell signaling. Curr. Opin. Cell Biol. 16 (2004) 162-168
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 162-168
-
-
Lefkowitz, R.J.1
Whalen, E.J.2
-
89
-
-
33751533776
-
New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors
-
Lefkowitz R.J., Rajagopal K., and Whalen E.J. New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors. Mol. Cell 24 (2006) 643-652
-
(2006)
Mol. Cell
, vol.24
, pp. 643-652
-
-
Lefkowitz, R.J.1
Rajagopal, K.2
Whalen, E.J.3
-
90
-
-
67650245968
-
Mdm2 Directs the Ubiquitination of {beta}-Arrestin-sequestered cAMP Phosphodiesterase-4D5
-
Li X., Baillie G.S., and Houslay M.D. Mdm2 Directs the Ubiquitination of {beta}-Arrestin-sequestered cAMP Phosphodiesterase-4D5. J. Biol. Chem. 284 (2009) 16170-16182
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16170-16182
-
-
Li, X.1
Baillie, G.S.2
Houslay, M.D.3
-
91
-
-
0033610892
-
beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor
-
Lin F.T., Daaka Y., and Lefkowitz R.J. beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J. Biol. Chem. 273 (1998) 31640-31643
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31640-31643
-
-
Lin, F.T.1
Daaka, Y.2
Lefkowitz, R.J.3
-
92
-
-
0037884961
-
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
-
Lin F., Hiesberger T., Cordes K., Sinclair A.M., Goldstein L.S., Somlo S., and Igarashi P. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc. Natl. Acad. Sci. USA 100 (2003) 5286-5291
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5286-5291
-
-
Lin, F.1
Hiesberger, T.2
Cordes, K.3
Sinclair, A.M.4
Goldstein, L.S.5
Somlo, S.6
Igarashi, P.7
-
93
-
-
55549102963
-
Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface
-
Lin C.H., MacGurn J.A., Chu T., Stefan C.J., and Emr S.D. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135 (2008) 714-725
-
(2008)
Cell
, vol.135
, pp. 714-725
-
-
Lin, C.H.1
MacGurn, J.A.2
Chu, T.3
Stefan, C.J.4
Emr, S.D.5
-
94
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
-
(2004)
Annu. Rev. Cell Dev. Biol.
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
95
-
-
61349130027
-
Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance
-
Luan B., Zhao J., Wu H., Duan B., Shu G., Wang X., Li D., Jia W., Kang J., and Pei G. Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance. Nature 457 (2009) 1146-1149
-
(2009)
Nature
, vol.457
, pp. 1146-1149
-
-
Luan, B.1
Zhao, J.2
Wu, H.3
Duan, B.4
Shu, G.5
Wang, X.6
Li, D.7
Jia, W.8
Kang, J.9
Pei, G.10
-
96
-
-
47849128759
-
M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms
-
Luo J., Busillo J.M., and Benovic J.L. M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms. Mol. Pharmacol. 74 (2008) 338-347
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 338-347
-
-
Luo, J.1
Busillo, J.M.2
Benovic, J.L.3
-
97
-
-
0345896723
-
Signaling in time and space: G protein-coupled receptors and mitogen-activated protein kinases
-
Luttrell D.K., and Luttrell L.M. Signaling in time and space: G protein-coupled receptors and mitogen-activated protein kinases. Assay Drug Dev. Technol. 1 (2003) 327-338
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, pp. 327-338
-
-
Luttrell, D.K.1
Luttrell, L.M.2
-
98
-
-
0033613938
-
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
-
Luttrell L.M., Ferguson S.S., Daaka Y., Miller W.E., Maudsley S., Della Rocca G.J., Lin F., Kawakatsu H., Owada K., Luttrell D.K., et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 283 (1999) 655-661
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
Miller, W.E.4
Maudsley, S.5
Della Rocca, G.J.6
Lin, F.7
Kawakatsu, H.8
Owada, K.9
Luttrell, D.K.10
-
99
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
-
Luttrell L.M., Roudabush F.L., Choy E.W., Miller W.E., Field M.E., Pierce K.L., and Lefkowitz R.J. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc. Natl. Acad. Sci. USA 98 (2001) 2449-2454
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2449-2454
-
-
Luttrell, L.M.1
Roudabush, F.L.2
Choy, E.W.3
Miller, W.E.4
Field, M.E.5
Pierce, K.L.6
Lefkowitz, R.J.7
-
100
-
-
33846998992
-
Beta-arrestin signaling and regulation of transcription
-
Ma L., and Pei G. Beta-arrestin signaling and regulation of transcription. J. Cell Sci. 120 (2007) 213-218
-
(2007)
J. Cell Sci.
, vol.120
, pp. 213-218
-
-
Ma, L.1
Pei, G.2
-
101
-
-
33845958896
-
Mu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neurons
-
Macey T.A., Lowe J.D., and Chavkin C. Mu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neurons. J. Biol. Chem. 281 (2006) 34515-34524
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34515-34524
-
-
Macey, T.A.1
Lowe, J.D.2
Chavkin, C.3
-
102
-
-
0242412524
-
Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination
-
Martin N.P., Lefkowitz R.J., and Shenoy S.K. Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination. J. Biol. Chem. 278 (2003) 45954-45959
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45954-45959
-
-
Martin, N.P.1
Lefkowitz, R.J.2
Shenoy, S.K.3
-
103
-
-
27744484694
-
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
-
May S.R., Ashique A.M., Karlen M., Wang B., Shen Y., Zarbalis K., Reiter J., Ericson J., and Peterson A.S. Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev. Biol. 287 (2005) 378-389
-
(2005)
Dev. Biol.
, vol.287
, pp. 378-389
-
-
May, S.R.1
Ashique, A.M.2
Karlen, M.3
Wang, B.4
Shen, Y.5
Zarbalis, K.6
Reiter, J.7
Ericson, J.8
Peterson, A.S.9
-
104
-
-
0034678908
-
Transcriptional control by the TGF-beta/Smad signaling system
-
Massague J., and Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J. 19 (2000) 1745-1754
-
(2000)
EMBO J.
, vol.19
, pp. 1745-1754
-
-
Massague, J.1
Wotton, D.2
-
105
-
-
0029047609
-
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
-
Matsuno K., Diederich R.J., Go M.J., Blaumueller C.M., and Artavanis-Tsakonas S. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121 (1995) 2633-2644
-
(1995)
Development
, vol.121
, pp. 2633-2644
-
-
Matsuno, K.1
Diederich, R.J.2
Go, M.J.3
Blaumueller, C.M.4
Artavanis-Tsakonas, S.5
-
106
-
-
0034711397
-
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3
-
McDonald P.H., Chow C.W., Miller W.E., Laporte S.A., Field M.E., Lin F.T., Davis R.J., and Lefkowitz R.J. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290 (2000) 1574-1577
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
Chow, C.W.2
Miller, W.E.3
Laporte, S.A.4
Field, M.E.5
Lin, F.T.6
Davis, R.J.7
Lefkowitz, R.J.8
-
107
-
-
33646868636
-
Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation
-
McLaughlin N.J., Banerjee A., Kelher M.R., Gamboni-Robertson F., Hamiel C., Sheppard F.R., Moore E.E., and Silliman C.C. Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation. J. Immunol. 176 (2006) 7039-7050
-
(2006)
J. Immunol.
, vol.176
, pp. 7039-7050
-
-
McLaughlin, N.J.1
Banerjee, A.2
Kelher, M.R.3
Gamboni-Robertson, F.4
Hamiel, C.5
Sheppard, F.R.6
Moore, E.E.7
Silliman, C.C.8
-
108
-
-
56749092253
-
Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways
-
McLennan G.P., Kiss A., Miyatake M., Belcheva M.M., Chambers K.T., Pozek J.J., Mohabbat Y., Moyer R.A., Bohn L.M., and Coscia C.J. Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways. J. Neurochem. 107 (2008) 1753-1765
-
(2008)
J. Neurochem.
, vol.107
, pp. 1753-1765
-
-
McLennan, G.P.1
Kiss, A.2
Miyatake, M.3
Belcheva, M.M.4
Chambers, K.T.5
Pozek, J.J.6
Mohabbat, Y.7
Moyer, R.A.8
Bohn, L.M.9
Coscia, C.J.10
-
109
-
-
33749590571
-
Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2
-
Meloni A.R., Fralish G.B., Kelly P., Salahpour A., Chen J.K., Wechsler-Reya R.J., Lefkowitz R.J., and Caron M.G. Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2. Mol. Cell. Biol. 26 (2006) 7550-7560
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7550-7560
-
-
Meloni, A.R.1
Fralish, G.B.2
Kelly, P.3
Salahpour, A.4
Chen, J.K.5
Wechsler-Reya, R.J.6
Lefkowitz, R.J.7
Caron, M.G.8
-
110
-
-
18844411824
-
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation
-
Milasta S., Evans N.A., Ormiston L., Wilson S., Lefkowitz R.J., and Milligan G. The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. Biochem. J. 387 (2005) 573-584
-
(2005)
Biochem. J.
, vol.387
, pp. 573-584
-
-
Milasta, S.1
Evans, N.A.2
Ormiston, L.3
Wilson, S.4
Lefkowitz, R.J.5
Milligan, G.6
-
111
-
-
0037821781
-
G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR
-
Miller W.E., Houtz D.A., Nelson C.D., Kolattukudy P.E., and Lefkowitz R.J. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR. J. Biol. Chem. 278 (2003) 21663-21671
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21663-21671
-
-
Miller, W.E.1
Houtz, D.A.2
Nelson, C.D.3
Kolattukudy, P.E.4
Lefkowitz, R.J.5
-
112
-
-
56649123195
-
Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control
-
Molla-Herman A., Boularan C., Ghossoub R., Scott M.G., Burtey A., Zarka M., Saunier S., Concordet J.P., Marullo S., and Benmerah A. Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control. PLoS ONE 3 (2008) e3728
-
(2008)
PLoS ONE
, vol.3
-
-
Molla-Herman, A.1
Boularan, C.2
Ghossoub, R.3
Scott, M.G.4
Burtey, A.5
Zarka, M.6
Saunier, S.7
Concordet, J.P.8
Marullo, S.9
Benmerah, A.10
-
114
-
-
28544440935
-
Regulation of Notch signalling by non-visual beta-arrestin
-
Mukherjee A., Veraksa A., Bauer A., Rosse C., Camonis J., and Artavanis-Tsakonas S. Regulation of Notch signalling by non-visual beta-arrestin. Nat. Cell Biol. 7 (2005) 1191-1201
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1191-1201
-
-
Mukherjee, A.1
Veraksa, A.2
Bauer, A.3
Rosse, C.4
Camonis, J.5
Artavanis-Tsakonas, S.6
-
115
-
-
33846471122
-
Proteasome-independent functions of ubiquitin in endocytosis and signaling
-
Mukhopadhyay D., and Riezman H. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315 (2007) 201-205
-
(2007)
Science
, vol.315
, pp. 201-205
-
-
Mukhopadhyay, D.1
Riezman, H.2
-
116
-
-
0033604515
-
Hedgehog signal transduction: from flies to vertebrates
-
Murone M., Rosenthal A., and de Sauvage F.J. Hedgehog signal transduction: from flies to vertebrates. Exp. Cell Res. 253 (1999) 25-33
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 25-33
-
-
Murone, M.1
Rosenthal, A.2
de Sauvage, F.J.3
-
117
-
-
66249141288
-
The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42
-
Mythreye K., and Blobe G.C. The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. Proc. Natl. Acad. Sci. USA 106 (2009) 8221-8226
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8221-8226
-
-
Mythreye, K.1
Blobe, G.C.2
-
118
-
-
33846834013
-
Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins
-
Nelson C.D., Perry S.J., Regier D.S., Prescott S.M., Topham M.K., and Lefkowitz R.J. Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science 315 (2007) 663-666
-
(2007)
Science
, vol.315
, pp. 663-666
-
-
Nelson, C.D.1
Perry, S.J.2
Regier, D.S.3
Prescott, S.M.4
Topham, M.K.5
Lefkowitz, R.J.6
-
119
-
-
51049084661
-
Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor
-
Nelson C.D., Kovacs J.J., Nobles K.N., Whalen E.J., and Lefkowitz R.J. Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. J. Biol. Chem. 238 (2008) 21093-21101
-
(2008)
J. Biol. Chem.
, vol.238
, pp. 21093-21101
-
-
Nelson, C.D.1
Kovacs, J.J.2
Nobles, K.N.3
Whalen, E.J.4
Lefkowitz, R.J.5
-
120
-
-
69949120070
-
Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo
-
Ocbina P.J., Tuson M., and Anderson K.V. Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo. PLoS ONE 4 (2009) e6839
-
(2009)
PLoS ONE
, vol.4
-
-
Ocbina, P.J.1
Tuson, M.2
Anderson, K.V.3
-
121
-
-
57049085407
-
G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling
-
Ogden S.K., Fei D.L., Schilling N.S., Ahmed Y.F., Hwa J., and Robbins D.J. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Nature 456 (2008) 967-970
-
(2008)
Nature
, vol.456
, pp. 967-970
-
-
Ogden, S.K.1
Fei, D.L.2
Schilling, N.S.3
Ahmed, Y.F.4
Hwa, J.5
Robbins, D.J.6
-
122
-
-
48349131772
-
S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking
-
Ozawa K., Whalen E.J., Nelson C.D., Mu Y., Hess D.T., Lefkowitz R.J., and Stamler J.S. S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Mol. Cell 31 (2008) 395-405
-
(2008)
Mol. Cell
, vol.31
, pp. 395-405
-
-
Ozawa, K.1
Whalen, E.J.2
Nelson, C.D.3
Mu, Y.4
Hess, D.T.5
Lefkowitz, R.J.6
Stamler, J.S.7
-
123
-
-
46249125254
-
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
-
Park T.J., Mitchell B.J., Abitua P.B., Kintner C., and Wallingford J.B. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat. Genet. 40 (2008) 871-879
-
(2008)
Nat. Genet.
, vol.40
, pp. 871-879
-
-
Park, T.J.1
Mitchell, B.J.2
Abitua, P.B.3
Kintner, C.4
Wallingford, J.B.5
-
124
-
-
0037174646
-
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins
-
Perry S.J., Baillie G.S., Kohout T.A., McPhee I., Magiera M.M., Ang K.L., Miller W.E., McLean A.J., Conti M., Houslay M.D., and Lefkowitz R.J. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science 298 (2002) 834-836
-
(2002)
Science
, vol.298
, pp. 834-836
-
-
Perry, S.J.1
Baillie, G.S.2
Kohout, T.A.3
McPhee, I.4
Magiera, M.M.5
Ang, K.L.6
Miller, W.E.7
McLean, A.J.8
Conti, M.9
Houslay, M.D.10
Lefkowitz, R.J.11
-
125
-
-
59349091148
-
Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase
-
Philipp M., Fralish G.B., Meloni A.R., Chen W., MacInnes A.W., Barak L.S., and Caron M.G. Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. Mol. Biol. Cell 19 (2008) 5478-5489
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5478-5489
-
-
Philipp, M.1
Fralish, G.B.2
Meloni, A.R.3
Chen, W.4
MacInnes, A.W.5
Barak, L.S.6
Caron, M.G.7
-
126
-
-
0034652310
-
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
-
Pierce K.L., Maudsley S., Daaka Y., Luttrell L.M., and Lefkowitz R.J. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc. Natl. Acad. Sci. USA 97 (2000) 1489-1494
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1489-1494
-
-
Pierce, K.L.1
Maudsley, S.2
Daaka, Y.3
Luttrell, L.M.4
Lefkowitz, R.J.5
-
127
-
-
33947375174
-
Physiological roles of G protein-coupled receptor kinases and arrestins
-
Premont R.T., and Gainetdinov R.R. Physiological roles of G protein-coupled receptor kinases and arrestins. Annu. Rev. Physiol. 69 (2007) 511-534
-
(2007)
Annu. Rev. Physiol.
, vol.69
, pp. 511-534
-
-
Premont, R.T.1
Gainetdinov, R.R.2
-
128
-
-
13444270337
-
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
-
Ren X.R., Reiter E., Ahn S., Kim J., Chen W., and Lefkowitz R.J. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor. Proc. Natl. Acad. Sci. USA 102 (2005) 1448-1453
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1448-1453
-
-
Ren, X.R.1
Reiter, E.2
Ahn, S.3
Kim, J.4
Chen, W.5
Lefkowitz, R.J.6
-
129
-
-
0033927390
-
kurtz, a novel nonvisual arrestin, is an essential neural gene in Drosophila
-
Roman G., He J., and Davis R.L. kurtz, a novel nonvisual arrestin, is an essential neural gene in Drosophila. Genetics 155 (2000) 1281-1295
-
(2000)
Genetics
, vol.155
, pp. 1281-1295
-
-
Roman, G.1
He, J.2
Davis, R.L.3
-
130
-
-
27144460671
-
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
-
Ross A.J., May-Simera H., Eichers E.R., Kai M., Hill J., Jagger D.J., Leitch C.C., Chapple J.P., Munro P.M., Fisher S., et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 37 (2005) 1135-1140
-
(2005)
Nat. Genet.
, vol.37
, pp. 1135-1140
-
-
Ross, A.J.1
May-Simera, H.2
Eichers, E.R.3
Kai, M.4
Hill, J.5
Jagger, D.J.6
Leitch, C.C.7
Chapple, J.P.8
Munro, P.M.9
Fisher, S.10
-
131
-
-
33750208522
-
Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2
-
Salcedo A., Mayor Jr. F., and Penela P. Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2. EMBO J. 25 (2006) 4752-4762
-
(2006)
EMBO J.
, vol.25
, pp. 4752-4762
-
-
Salcedo, A.1
Mayor Jr., F.2
Penela, P.3
-
133
-
-
38949210817
-
Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo
-
Schmid C.L., Raehal K.M., and Bohn L.M. Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo. Proc. Natl. Acad. Sci. USA 105 (2008) 1079-1084
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1079-1084
-
-
Schmid, C.L.1
Raehal, K.M.2
Bohn, L.M.3
-
134
-
-
33646263875
-
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins
-
Scott M.G., Pierotti V., Storez H., Lindberg E., Thuret A., Muntaner O., Labbe-Jullie C., Pitcher J.A., and Marullo S. Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Mol. Cell. Biol. 26 (2006) 3432-3445
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3432-3445
-
-
Scott, M.G.1
Pierotti, V.2
Storez, H.3
Lindberg, E.4
Thuret, A.5
Muntaner, O.6
Labbe-Jullie, C.7
Pitcher, J.A.8
Marullo, S.9
-
135
-
-
34247573976
-
Seven-transmembrane receptors and ubiquitination
-
Shenoy S.K. Seven-transmembrane receptors and ubiquitination. Circ. Res. 100 (2007) 1142-1154
-
(2007)
Circ. Res.
, vol.100
, pp. 1142-1154
-
-
Shenoy, S.K.1
-
136
-
-
0037737763
-
Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination
-
Shenoy S.K., and Lefkowitz R.J. Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. J. Biol. Chem. 278 (2003) 14498-14506
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14498-14506
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
137
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
-
Shenoy S.K., McDonald P.H., Kohout T.A., and Lefkowitz R.J. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science 294 (2001) 1307-1313
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
McDonald, P.H.2
Kohout, T.A.3
Lefkowitz, R.J.4
-
138
-
-
33644857279
-
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor
-
Shenoy S.K., Drake M.T., Nelson C.D., Houtz D.A., Xiao K., Madabushi S., Reiter E., Premont R.T., Lichtarge O., and Lefkowitz R.J. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J. Biol. Chem. 281 (2006) 1261-1273
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1261-1273
-
-
Shenoy, S.K.1
Drake, M.T.2
Nelson, C.D.3
Houtz, D.A.4
Xiao, K.5
Madabushi, S.6
Reiter, E.7
Premont, R.T.8
Lichtarge, O.9
Lefkowitz, R.J.10
-
139
-
-
35748944113
-
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation
-
Shenoy S.K., Barak L.S., Xiao K., Ahn S., Berthouze M., Shukla A.K., Luttrell L.M., and Lefkowitz R.J. Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. J. Biol. Chem. 282 (2007) 29549-29562
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 29549-29562
-
-
Shenoy, S.K.1
Barak, L.S.2
Xiao, K.3
Ahn, S.4
Berthouze, M.5
Shukla, A.K.6
Luttrell, L.M.7
Lefkowitz, R.J.8
-
140
-
-
52049117442
-
Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor
-
Shenoy S.K., Xiao K., Venkataramanan V., Snyder P.M., Freedman N.J., and Weissman A.M. Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. J. Biol. Chem. 283 (2008) 22166-22176
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22166-22176
-
-
Shenoy, S.K.1
Xiao, K.2
Venkataramanan, V.3
Snyder, P.M.4
Freedman, N.J.5
Weissman, A.M.6
-
141
-
-
66149116039
-
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
-
Shenoy S.K., Modi A.S., Shukla A.K., Xiao K., Berthouze M., Ahn S., Wilkinson K.D., Miller W.E., and Lefkowitz R.J. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proc. Natl. Acad. Sci. USA 106 (2009) 6650-6655
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 6650-6655
-
-
Shenoy, S.K.1
Modi, A.S.2
Shukla, A.K.3
Xiao, K.4
Berthouze, M.5
Ahn, S.6
Wilkinson, K.D.7
Miller, W.E.8
Lefkowitz, R.J.9
-
142
-
-
33744943284
-
The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain
-
Shi H., Rojas R., Bonifacino J.S., and Hurley J.H. The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat. Struct. Mol. Biol. 13 (2006) 540-548
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 540-548
-
-
Shi, H.1
Rojas, R.2
Bonifacino, J.S.3
Hurley, J.H.4
-
143
-
-
0032481312
-
Role of TAK1 and TAB1 in BMP signaling in early Xenopus development
-
Shibuya H., Iwata H., Masuyama N., Gotoh Y., Yamaguchi K., Irie K., Matsumoto K., Nishida E., and Ueno N. Role of TAK1 and TAB1 in BMP signaling in early Xenopus development. EMBO J. 17 (1998) 1019-1028
-
(1998)
EMBO J.
, vol.17
, pp. 1019-1028
-
-
Shibuya, H.1
Iwata, H.2
Masuyama, N.3
Gotoh, Y.4
Yamaguchi, K.5
Irie, K.6
Matsumoto, K.7
Nishida, E.8
Ueno, N.9
-
144
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim J.H., Xiao C., Paschal A.E., Bailey S.T., Rao P., Hayden M.S., Lee K.Y., Bussey C., Steckel M., Tanaka N., et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 19 (2005) 2668-2681
-
(2005)
Genes Dev.
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
Xiao, C.2
Paschal, A.E.3
Bailey, S.T.4
Rao, P.5
Hayden, M.S.6
Lee, K.Y.7
Bussey, C.8
Steckel, M.9
Tanaka, N.10
-
145
-
-
0034877139
-
Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors
-
Siddle K., Urso B., Niesler C.A., Cope D.L., Molina L., Surinya K.H., and Soos M.A. Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors. Biochem. Soc. Trans. 29 (2001) 513-525
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 513-525
-
-
Siddle, K.1
Urso, B.2
Niesler, C.A.3
Cope, D.L.4
Molina, L.5
Surinya, K.H.6
Soos, M.A.7
-
146
-
-
44349129654
-
Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells
-
Sonoda N., Imamura T., Yoshizaki T., Babendure J.L., Lu J.C., and Olefsky J.M. Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proc. Natl. Acad. Sci. USA 105 (2008) 6614-6619
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6614-6619
-
-
Sonoda, N.1
Imamura, T.2
Yoshizaki, T.3
Babendure, J.L.4
Lu, J.C.5
Olefsky, J.M.6
-
147
-
-
53349164136
-
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
-
Sorrentino A., Thakur N., Grimsby S., Marcusson A., von Bulow V., Schuster N., Zhang S., Heldin C.H., and Landstrom M. The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat. Cell Biol. 10 (2008) 1199-1207
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1199-1207
-
-
Sorrentino, A.1
Thakur, N.2
Grimsby, S.3
Marcusson, A.4
von Bulow, V.5
Schuster, N.6
Zhang, S.7
Heldin, C.H.8
Landstrom, M.9
-
148
-
-
0037147145
-
Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
-
Sun Y., Cheng Z., Ma L., and Pei G. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J. Biol. Chem. 277 (2002) 49212-49219
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49212-49219
-
-
Sun, Y.1
Cheng, Z.2
Ma, L.3
Pei, G.4
-
149
-
-
0038497966
-
The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity
-
Takeyama K., Aguiar R.C., Gu L., He C., Freeman G.J., Kutok J.L., Aster J.C., and Shipp M.A. The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity. J. Biol. Chem. 278 (2003) 21930-21937
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21930-21937
-
-
Takeyama, K.1
Aguiar, R.C.2
Gu, L.3
He, C.4
Freeman, G.J.5
Kutok, J.L.6
Aster, J.C.7
Shipp, M.A.8
-
150
-
-
34247863920
-
pVHL and GSK3beta are components of a primary cilium-maintenance signalling network
-
Thoma C.R., Frew I.J., Hoerner C.R., Montani M., Moch H., and Krek W. pVHL and GSK3beta are components of a primary cilium-maintenance signalling network. Nat. Cell Biol. 9 (2007) 588-595
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 588-595
-
-
Thoma, C.R.1
Frew, I.J.2
Hoerner, C.R.3
Montani, M.4
Moch, H.5
Krek, W.6
-
151
-
-
0037088585
-
beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
-
Tohgo A., Pierce K.L., Choy E.W., Lefkowitz R.J., and Luttrell L.M. beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J. Biol. Chem. 277 (2002) 9429-9436
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9429-9436
-
-
Tohgo, A.1
Pierce, K.L.2
Choy, E.W.3
Lefkowitz, R.J.4
Luttrell, L.M.5
-
152
-
-
31744436876
-
Divergence of hedgehog signal transduction mechanism between Drosophila and mammals
-
Varjosalo M., Li S.P., and Taipale J. Divergence of hedgehog signal transduction mechanism between Drosophila and mammals. Dev. Cell 10 (2006) 177-186
-
(2006)
Dev. Cell
, vol.10
, pp. 177-186
-
-
Varjosalo, M.1
Li, S.P.2
Taipale, J.3
-
153
-
-
67749117934
-
Signal integration by JNK and p38 MAPK pathways in cancer development
-
Wagner E.F., and Nebreda A.R. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9 (2009) 537-549
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
154
-
-
66449111715
-
beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice
-
Walters R.W., Shukla A.K., Kovacs J.J., Violin J.D., DeWire S.M., Lam C.M., Chen J.R., Muehlbauer M.J., Whalen E.J., and Lefkowitz R.J. beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. J. Clin. Invest. 119 (2009) 1312-1321
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1312-1321
-
-
Walters, R.W.1
Shukla, A.K.2
Kovacs, J.J.3
Violin, J.D.4
DeWire, S.M.5
Lam, C.M.6
Chen, J.R.7
Muehlbauer, M.J.8
Whalen, E.J.9
Lefkowitz, R.J.10
-
155
-
-
33747149560
-
Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase
-
Wang P., and DeFea K.A. Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase. Biochemistry 45 (2006) 9374-9385
-
(2006)
Biochemistry
, vol.45
, pp. 9374-9385
-
-
Wang, P.1
DeFea, K.A.2
-
156
-
-
33645096878
-
Structure-function analysis of Frizzleds
-
Wang H.Y., Liu T., and Malbon C.C. Structure-function analysis of Frizzleds. Cell. Signal. 18 (2006) 934-941
-
(2006)
Cell. Signal.
, vol.18
, pp. 934-941
-
-
Wang, H.Y.1
Liu, T.2
Malbon, C.C.3
-
157
-
-
33748749459
-
Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation
-
Wang Q., Lu R., Zhao J., and Limbird L.E. Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation. J. Biol. Chem. 281 (2006) 25948-25955
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25948-25955
-
-
Wang, Q.1
Lu, R.2
Zhao, J.3
Limbird, L.E.4
-
158
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
-
Wang Y., Tang Y., Teng L., Wu Y., Zhao X., and Pei G. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 7 (2006) 139-147
-
(2006)
Nat. Immunol.
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
Wu, Y.4
Zhao, X.5
Pei, G.6
-
159
-
-
0037959910
-
The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia
-
Watanabe D., Saijoh Y., Nonaka S., Sasaki G., Ikawa Y., Yokoyama T., and Hamada H. The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia. Development 130 (2003) 1725-1734
-
(2003)
Development
, vol.130
, pp. 1725-1734
-
-
Watanabe, D.1
Saijoh, Y.2
Nonaka, S.3
Sasaki, G.4
Ikawa, Y.5
Yokoyama, T.6
Hamada, H.7
-
160
-
-
11144285406
-
Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway
-
Wilbanks A.M., Fralish G.B., Kirby M.L., Barak L.S., Li Y.X., and Caron M.G. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science 306 (2004) 2264-2267
-
(2004)
Science
, vol.306
, pp. 2264-2267
-
-
Wilbanks, A.M.1
Fralish, G.B.2
Kirby, M.L.3
Barak, L.S.4
Li, Y.X.5
Caron, M.G.6
-
161
-
-
61749097816
-
Tgf-beta superfamily signaling in embryonic development and homeostasis
-
Wu M.Y., and Hill C.S. Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev. Cell 16 (2009) 329-343
-
(2009)
Dev. Cell
, vol.16
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
162
-
-
34547512353
-
Functional specialization of beta-arrestin interactions revealed by proteomic analysis
-
Xiao K., McClatchy D.B., Shukla A.K., Zhao Y., Chen M., Shenoy S.K., Yates III J.R., and Lefkowitz R.J. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proc. Natl. Acad. Sci. USA 104 (2007) 12011-12016
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12011-12016
-
-
Xiao, K.1
McClatchy, D.B.2
Shukla, A.K.3
Zhao, Y.4
Chen, M.5
Shenoy, S.K.6
Yates III, J.R.7
Lefkowitz, R.J.8
-
163
-
-
65549101582
-
Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway
-
Yam P.T., Langlois S.D., Morin S., and Charron F. Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron 62 (2009) 349-362
-
(2009)
Neuron
, vol.62
, pp. 349-362
-
-
Yam, P.T.1
Langlois, S.D.2
Morin, S.3
Charron, F.4
-
164
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K., Shirakabe K., Shibuya H., Irie K., Oishi I., Ueno N., Taniguchi T., Nishida E., and Matsumoto K. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 270 (1995) 2008-2011
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
165
-
-
52049111663
-
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
-
Yamashita M., Fatyol K., Jin C., Wang X., Liu Z., and Zhang Y.E. TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Mol. Cell 31 (2008) 918-924
-
(2008)
Mol. Cell
, vol.31
, pp. 918-924
-
-
Yamashita, M.1
Fatyol, K.2
Jin, C.3
Wang, X.4
Liu, Z.5
Zhang, Y.E.6
-
166
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang D.D., Kuan C.Y., Whitmarsh A.J., Rincon M., Zheng T.S., Davis R.J., Rakic P., and Flavell R.A. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389 (1997) 865-870
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
-
167
-
-
69449101160
-
The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2
-
You H.J., How T., and Blobe G.C. The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2. Carcinogenesis 30 (2009) 1281-1287
-
(2009)
Carcinogenesis
, vol.30
, pp. 1281-1287
-
-
You, H.J.1
How, T.2
Blobe, G.C.3
-
168
-
-
14044252936
-
Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation
-
Yun M.S., Kim S.E., Jeon S.H., Lee J.S., and Choi K.Y. Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation. J. Cell Sci. 118 (2005) 313-322
-
(2005)
J. Cell Sci.
, vol.118
, pp. 313-322
-
-
Yun, M.S.1
Kim, S.E.2
Jeon, S.H.3
Lee, J.S.4
Choi, K.Y.5
-
169
-
-
58149213801
-
Non-Smad pathways in TGF-beta signaling
-
Zhang Y.E. Non-Smad pathways in TGF-beta signaling. Cell Res. 19 (2009) 128-139
-
(2009)
Cell Res.
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
170
-
-
0031393975
-
Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization
-
Zhang J., Ferguson S.S., Barak L.S., Aber M.J., Giros B., Lefkowitz R.J., and Caron M.G. Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization. Receptors Channels 5 (1997) 193-199
-
(1997)
Receptors Channels
, vol.5
, pp. 193-199
-
-
Zhang, J.1
Ferguson, S.S.2
Barak, L.S.3
Aber, M.J.4
Giros, B.5
Lefkowitz, R.J.6
Caron, M.G.7
-
171
-
-
67649856866
-
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
-
Zidar D.A., Violin J.D., Whalen E.J., and Lefkowitz R.J. Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands. Proc. Natl. Acad. Sci. USA 106 (2009) 9649-9654
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9649-9654
-
-
Zidar, D.A.1
Violin, J.D.2
Whalen, E.J.3
Lefkowitz, R.J.4
-
172
-
-
34547107639
-
Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
-
Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., and DeFea K.A. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. 282 (2007) 20634-20646
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20634-20646
-
-
Zoudilova, M.1
Kumar, P.2
Ge, L.3
Wang, P.4
Bokoch, G.M.5
DeFea, K.A.6
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