Distinct β-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation

Journal of Biological Chemistry

Volumn 281, Issue 16, 2006, Pages 10856-10864

  Gesty Palmer, Diane ^a,b   Chen, Minyong ^a   Reiter, Eric ^c   Ahn, Seungkirl ^a   Nelson, Christopher D ^a   Wang, Shuntai ^d   Eckhardt, Allen E ^d   Cowan, Conrad L ^d   Spurney, Robert F ^a   Luttrell, Louis M ^e,f   Lefkowitz, Robert J ^a,g  

^a DUKE UNIVERSITY   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

^c CEMAGREF   (France)

^d Xsira Pharmaceuticals   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; CONFORMATIONS; ENZYMES; POLYPEPTIDES; RNA;

ERK ACTIVITY; PARATHYROID HORMONE RECEPTOR; TRANSDUCTION PATHWAYS;

HORMONES;

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BETA ARRESTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PARATHYROID HORMONE RECEPTOR; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ARRESTINS; CELL LINE; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; DNA, COMPLEMENTARY; GTP-BINDING PROTEINS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INDOLES; ISOQUINOLINES; LIGANDS; MALEIMIDES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; PHOSPHORYLATION; PROTEIN KINASES; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SULFONAMIDES; TIME FACTORS; TRANSFECTION;

EID: 33744957160     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513380200     Document Type: Article

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