Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 9, 2003, Pages 5286-5291

  Lin, Fangming ^a   Hiesberger, Thomas ^a   Cordes, Kimberly ^a   Sinclair, Angus M ^a   Goldstein, Lawrence S B ^b   Somlo, Stefan ^c   Igarashi, Peter ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; KINESIN; KINESIN 2; MYC PROTEIN; PROTEIN P21; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIRTH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLOGY; DISEASE ASSOCIATION; EMBRYO DEATH; EUKARYOTIC FLAGELLUM; GENE; GENE INACTIVATION; GENETIC CODE; KIDNEY FAILURE; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUBULE EPITHELIUM; KIF3A GENE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CALCIUM-BINDING PROTEINS; CILIA; DNA PRIMERS; IN SITU NICK-END LABELING; KIDNEY; KINESIN; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; MUSCLE PROTEINS; POLYCYSTIC KIDNEY DISEASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; EUKARYOTA;

EID: 0037884961     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0836980100     Document Type: Article

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