Protease-activated receptor-2 simultaneously directs β-arrestin-1- dependent inhibition and Gαq-dependent activation of phosphatidylinositol 3-kinase

Biochemistry

Volumn 45, Issue 31, 2006, Pages 9374-9385

  Wang, Ping ^a   DeFea, Kathryn A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYST ACTIVITY; PRECIPITATION (CHEMICAL); SIZE EXCLUSION CHROMATOGRAPHY;

CO-IMMUNOPRECIPITATION; G-PROTEIN COUPLED RECEPTOR (GPCR); G-PROTEINS; SIGNALING SCAFFOLD;

ENZYME INHIBITION;

BETA ARRESTIN 1; CALCIUM ION; FOCAL ADHESION KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P110ALPHA; PROTEIN P85; PROTEIN TYROSINE KINASE; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CATALYSIS; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PSEUDOPODIUM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ARRESTINS; CHEMOTAXIS; ENZYME ACTIVATION; FOCAL ADHESION KINASE 2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; IMMUNOPRECIPITATION; MACROMOLECULAR SUBSTANCES; MICE; NIH 3T3 CELLS; PSEUDOPODIA; RECEPTOR, PAR-2; SRC-FAMILY KINASES;

EID: 33747149560     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0602617     Document Type: Article

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