G-protein-coupled receptor (GPCR) kinase phosphorylation and β-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21663-21671

  Miller, William E ^a,b   Houtz, Daniel A ^a   Nelson, Christopher D ^a   Kolattukudy, P E ^c   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ATTENUATION; BIOLOGICAL MEMBRANES; CELLS; VIRUSES;

PHOSPHORYLATION;

PROTEINS;

BETA ARRESTIN; CELL RECEPTOR; CHEMOKINE; G PROTEIN COUPLED RECEPTOR KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; PROTEIN; PROTEIN US28; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; VIRUS PATHOGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARRESTINS; BETA-ADRENERGIC RECEPTOR KINASE; CELL LINE; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE DELETION; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; TRANSFECTION; VIRAL PROTEINS;

ANIMALIA; CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5;

EID: 0037821781     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303219200     Document Type: Article

References (59)

1. Lefkowitz, R. J. (1998) J. Biol. Chem. 273, 18677-18680
2. Gutkind, J. S. (1998) J. Biol. Chem. 273, 1839-1842
3. Pierce, K. L., Luttrell, L. M., and Lefkowitz, R. J. (2001) Oncogene 20, 1532-1539
4. Koenig, J. A., and Edwardson, J. M. (1997) Trends Pharmacol. Sci. 18, 276-287
5. Hausdorff, W. P., Caron, M. G., and Lefkowitz, R. J. (1990) FASEB J. 4, 2881-2889
6. Ferguson, S. S., Barak, L. S., Zhang, J., and Caron, M. G. (1996) Can. J. Physiol. Pharmacol. 74, 1095-1110
7. Sibley, D. R., Benovic, J. L., Caron, M. G., and Lefkowitz, R. J. (1987) Cell 48, 913-922
8. Ahuja, S. K., and Murphy, P. M. (1993) J. Biol. Chem. 268, 20691-20694
9. Cesarman, E., Nador, R. G., Bai, F., Bohenzky, R. A., Russo, J. J., Moore, P. S., Chang, Y., and Knowles, D. M. (1996) J. Virol. 70, 8218-8223
10. Isegawa, Y., Ping, Z., Nakano, K., Sugimoto, N., and Yamanishi, K. (1998) J. Virol. 72, 6104-6112
11. Milne, R. S., Mattick, C., Nicholson, L., Devaraj, P., Alcami, A., and Gompels, U. A. (2000) J. Immunol. 164, 2396-2404
12. Margulies, B. J., Browne, H., and Gibson, W. (1996) Virology 225, 111-125
13. Neote, K., DiGregorio, D., Mak, J. Y., Horuk, R., and Schall, T. J. (1993) Cell 72, 415-425
14. Davis-Poynter, N. J., Lynch, D. M., Vally, H., Shellam, G. R., Rawlinson, W. D., Barrell, B. G., and Farrell, H. E. (1997) J. Virol. 71, 1521-1529
15. Davis-Poynter, N. J., Degli-Esposti, M., and Farrell, H. E. (1999) Intervirology 42, 331-341
16. Beisser, P. S., Vink, C., Van Dam, J. G., Grauls, G., Vanherle, S. J., and Bruggeman, C. A. (1998) J. Virol. 72, 2352-2363
17. Randolph-Habecker, J., Rahill, B., Torok-Storb, B., Vieira, J., Kolattukudy, P., Rovin, B., and Sedmak, D. (2002) Cytokine 19, 37-46
18. Beisser, P. S., Goh, C. S., Cohen, F. E., and Michelson, S. (2002) Curr. Top. Microbiol. Immunol. 269, 203-234
19. Casarosa, P., Bakker, R. A., Verzijl, D., Navis, M., Timmerman, H., Leurs, R., and Smit, M. J. (2001) J. Biol. Chem. 276, 1133-1137
20. Rosenkilde, M. M., Kledal, T. N., Brauner-Osborne, H., and Schwartz, T. W. (1999) J. Biol. Chem. 274, 956-961
21. Arvanitakis, L., Geras-Raaka, E., Varma, A., Gershengorn, M. C., and Cesarman, E. (1997) Nature 385, 347-350
22. Geras-Raaka, E., Varma, A., Ho, H., Clark-Lewis, I., and Gershengorn, M. C. (1998) J. Exp. Med. 188, 405-408
23. Waldhoer, M., Kledal, T. N., Farrell, H., and Schwartz, T. W. (2002) J. Virol. 76, 8161-8168
24. Gao, J. L., and Murphy, P. M. (1994) J. Biol. Chem. 269, 28539-28542
25. Haskell, C. A., Cleary, M. D., and Charo, I. F. (2000) J. Biol. Chem. 275, 34183-34189
26. Streblow, D. N., Soderberg-Naucler, C., Vieira, J., Smith, P., Wakabayashi, E., Ruchti, F., Mattison, K., Altschuler, Y., and Nelson, J. A. (1999) Cell 99, 511-520
27. Kuhn, D. E., Beall, C. J., and Kolattukudy, P. E. (1995) Biochem. Biophys. Res. Commun. 211, 325-330
28. Kledal, T. N., Rosenkilde, M. M., and Schwartz, T. W. (1998) FEBS Lett. 441, 209-214
29. Billstrom, M. A., Johnson, G. L., Avdi, N. J., and Worthen, G. S. (1998) J. Virol. 72, 5535-5544
30. Fraile-Ramos, A., Kledal, T. N., Pelchen-Matthews, A., Bowers, K., Schwartz, T. W., and Marsh, M. (2001) Mol. Biol. Cell 12, 1737-1749
31. Mokros, T., Rehm, A., Droese, J., Oppermann, M., Lipp, M., and Hopken, U. E. (2002) J. Biol. Chem. 277, 45122-45128
32. Sallese, M., Lacovelli, L., Storto, M., and De Blasi, A. (2001) Trends Pharmacol. Sci. 22, 168-169
33. Oakley, R. H., Laporte, S. A., Holt, J. A., Barak, L. S., and Caron, M. G. (1999) J. Biol. Chem. 274, 32248-32257
34. Oakley, R. H., Laporte, S. A., Holt, J. A., Caron, M. G., and Barak, L. S. (2000) J. Biol. Chem. 275, 17201-17210
35. Bohn, L. M., Lefkowitz, R. J., Gainetdinov, R. R., Peppel, K., Caron, M. G., and Lin, F. T. (1999) Science 286, 2495-2498
36. Fong, A. M., Premont, R. T., Richardson, R. M., Yu, Y. R., Lefkowitz, R. J., and Patel, D. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 7478-7483
37. Gainetdinov, R. R., Bohn, L. M., Walker, J. K., Laporte, S. A., Macrae, A. D., Caron, M. G., Lefkowitz, R. J., and Premont, R. T. (1999) Neuron 24, 1029-1036
38. Mueller, S. G., White, J. R., Schraw, W. P., Lam, V., and Richmond, A. (1997) J. Biol. Chem. 272, 8207-8214
39. Lefkowitz, R. J., Pitcher, J., Krueger, K., and Daaka, Y. (1998) Adv. Pharmacol. 42, 416-420
40. Richardson, R. M., Pridgen, B. C., Haribabu, B., and Snyderman, R. (2000) J. Biol. Chem. 275, 9201-9208
41. Fuchs, S. Y., Xie, B., Adler, V., Fried, V. A., Davis, R. J., and Ronai, Z. (1997) J. Biol. Chem. 272, 32163-32168
42. Tang, Y., Hu, L. A., Miller, W. E., Ringstad, N., Hall, R. A., Pitcher, J. A., DeCamilli, P., and Lefkowitz, R. J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 12559-12564
43. Freedman, N. J., Ament, A. S., Oppermann, M., Stoffel, R. H., Exum, S. T., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 17734-17743
44. Carman, C. V., Parent, J. L., Day, P. W., Pronin, A. N., Sternweis, P. M., Wedegaertner, P. B., Gilman, A. G., Benovic, J. L., and Kozasa, T. (1999) J. Biol. Chem. 274, 34483-34492
45. Sallese, M., Mariggio, S., D'Urbano, E., Iacovelli, L., and De Blasi, A. (2000) Mol. Pharmacol. 57, 826-831
46. DebBurman, S. K., Ptasienski, J., Boetticher, E., Lomasney, J. W., Benovic, J. L., and Hosey, M. M. (1995) J. Biol. Chem. 270, 5742-5747
47. Waldhoer, M., Casarosa, P., Rosenkilde, M. M., Smit, M. J., Leurs, R., Whistler, J. L., and Schwartz, T. W. (2003) J. Biol. Chem. 278, 19473-19482
48. Couty, J. P., Geras-Raaka, E., Weksler, B. B., and Gershengorn, M. C. (2001) J. Biol. Chem. 276, 33805-33811
49. Pierce, K. L., Premont, R. T., and Lefkowitz, R. J. (2002) Nat. Rev. Mol. Cell. Biol. 3, 639-650
50. Miller, W. E., and Lefkowitz, R. J. (2001) Curr. Opin. Cell Biol. 13, 139-145
51. Premont, R. T., Claing, A., Vitale, N., Freeman, J. L., Pitcher, J. A., Patton, W. A., Moss, J., Vaughan, M., and Lefkowitz, R. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14082-14087
52. Pitcher, J. A., Hall, R. A., Daaka, Y., Zhang, J., Ferguson, S. S., Hester, S., Miller, S., Caron, M. G., Lefkowitz, R. J., and Barak, L. S. (1998) J. Biol. Chem. 273, 12316-12324
53. Pronin, A. N., Morris, A. J., Surguchov, A., and Benovic, J. L. (2000) J. Biol. Chem. 275, 26515-26522
54. Luttrell, L. M., Ferguson, S. S. G., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F. T., Kawakatsu, H., Owada, K., Luttrell, D. K., Caron, M. G., and Lefkowitz, R. J. (1999) Science 283, 655-661
55. Claing, A., Laporte, S. A., Caron, M. G., and Lefkowitz, R. J. (2002) Prog. Neurobiol. 66, 61-79
56. McDonald, P. H., Chow, C. W., Miller, W. E., Laporte, S. A., Field, M. E., Lin, F. T., Davis, R. J., and Lefkowitz, R. J. (2000) Science 290, 1574-1577
57. Tohgo, A., Pierce, K. L., Choy, E. W., Lefkowitz, R. J., and Luttrell, L. M. (2002) J. Biol. Chem. 277, 9429-9436
58. Bais, C., Santomasso, B., Coso, O., Arvanitakis, L., Raaka, E. G., Gutkind, J. S., Asch, A. S., Cesarman, E., Gershengorn, M. C., Mesri, E. A., and Gerhengorn, M. C. (1998) Nature 391, 86-89
59. Munshi, N., Ganju, R. K., Avraham, S., Mesri, E. A., and Groopman, J. E. (1999) J. Biol. Chem. 274, 31863-31867