A β-Arrestin-dependent Scaffold Is Associated with Prolonged MAPK Activation in Pseudopodia during Protease-activated Receptor-2-induced Chemotaxis

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 34418-34426

  Ge, Lan ^a   Ly, Youly ^a   Hollenberg, Morley ^c   DeFea, Kathryn ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME KINETICS; FLAMMABILITY; TUMORS;

CELL MOTILITY;

BIOCHEMISTRY;

BETA ARRESTIN; F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEINASE ACTIVATED RECEPTOR 2; ACTIN; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE; PHOTOPROTEIN; RETINA S ANTIGEN; THROMBIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL MIGRATION; CELL MOTILITY; CHEMOTAXIS; CONFOCAL MICROSCOPY; ENZYME ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FAMILY; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; PSEUDOPODIUM; WOUND HEALING; ANIMAL; BIOLOGICAL MODEL; CELL MOTION; CELL STRAIN 3T3; CHEMISTRY; CYTOSOL; DOMINANT GENE; ENDOSOME; ENZYMOLOGY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; MACROPHAGE; METABOLISM; MUTATION; PROTEIN BINDING; SERODIAGNOSIS; SIGNAL TRANSDUCTION;

ANIMALIA; RICKETTSIA SP. PAR;

3T3 CELLS; ACTINS; ANIMALS; ARRESTINS; CELL MOVEMENT; CHEMOTAXIS; CYTOSOL; ENDOSOMES; ENZYME ACTIVATION; FLOW CYTOMETRY; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MUTATION; PEPTIDES; PRECIPITIN TESTS; PROTEIN BINDING; PSEUDOPODIA; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TRANSFECTION;

EID: 0141483377     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300573200     Document Type: Article

References (36)

1. Parent, C. A., and Devreotes, P. N. (1999) Science 284, 765-770
2. Miki, H., Fukuda, M., Nishida, E., and Takenawa, T. (1999) J. Biol. Chem. 274, 27605-27609
3. Klemke, R. L., Cai, S., Giannini, A. L., Gallagher, P. J., de Lanerolle, P., and Cheresh, D. A. (1997) J. Cell Biol. 137, 481-492
4. Brahmbhatt, A. A., and Klemke, R. L. (2003) J. Biol. Chem. 278, 13016-13025
5. Sun, Y., Cheng, Z., Ma, L., and Pei, G. (2002) J. Biol. Chem. 277, 49212-49219
6. Hughes, P. E., Oertli, B., Hansen, M., Chou, F. L., Willumsen, B. M., and Ginsberg, M. H. (2002) Mol. Biol. Cell 13, 2256-2265
7. Miller, W., and Lefkowitz, R. J. (2001) Curr. Opin. Cell Biol. 13, 139-145
8. Fong, A. M., Premont, R. T., Richardson, R. M., Yu, Y. R., Lefkowitz, R. J., and Patel, D. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 7478-7483
9. Camerer, E., Huang, W., and Coughlin, S. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5255-5260
10. Dery, O., and Bunnett, N. W. (1999) Biochem. Soc. Trans. 27, 246-254
11. Takeuchi, T., Harris, J. L., Huang, W., Yan, K. W., Coughlin, S. R., and Craik, C. S. (2000) J. Biol. Chem. 275, 26333-26342
12. Dery, O., Corvera, C. U., Steinhoff, M., and Bunnett, N. W. (1998) Am. J. Physiol. 274, C1429-C1452
13. DeFea, K. A., Zalevsky, J., Thoma, M. S., Dery, O., Mullins, R. D., and Bunnett, N. W. (2000) J. Cell Biol. 148, 1267-1281
14. Luttrell, L. M., Roudabush, F. L., Choy, E. W., Miller, W., E., Field, M. E., Pierce, K. L., and Lefkowitz, R. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 2449-2454
15. McDonald, P. H., Chow, C. W., Miller, W. E., Laporte, S. A., Field, M. E., Lin, F. T., Davis, R. J., and Lefkowitz, R. J. (2000) Science 290, 1574-1577
16. Tohgo, A., Pierce, K. L., Choy, E. W., Lefkowitz, R. J., and Luttrell, L. M. (2002) J. Biol. Chem. 277, 9429-9436
17. Tohgo, A., Choy, E. W., Gesty-Palmer, D., Pierce, K. L., Laporte, S., Oakley, R. H., Caron, M. G., Lefkowitz, R. J., and Luttrell, L. M. (2003) J. Biol. Chem. 278, 6258-6267
18. Luttrell, L. M., Ferguson, S. S., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F., Kawakatsu, H., Owada, K., Luttrell, D. K., Caron, M. G., and Lefkowitz, R. J. (1999) Science 283, 655-661
19. DeFea, K. A., Vaughn, Z. D., O'Bryan, E. M., Nishijima, D., Dery, O., and Bunnett, N. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11086-11091
20. Lin, F. T., Daaka, Y., and Lefkowitz, R. J. (1998) J. Biol. Chem. 273, 31640-31643
21. Goel, R., Phillips-Mason, P. J., Raben, D. M., and Baldassare, J. J. (2002) J. Biol. Chem. 277, 18640-18648
22. Kamath, L., Meydani, A., Foss, F., and Kuliopulos, A. (2001) Cancer Res. 61, 5933-5940
23. Cho, S. Y., and Klemke, R. L. (2002) J. Cell Biol. 156, 725-736
24. Sasaoka, T., Rose, D. W., Jhun, B. H., Saltiel, A. R., Draznin, B., and Olefsky, J. M. (1994) J. Biol. Chem. 269, 13689-13694
25. Buettner, H. M., Lauffenburger, D. A., and Zigmond, S. H. (1989) J. Immunol. Methods 123, 25-37
26. Trejo, J., Connolly, A. J., and Coughlin, S. R. (1996) J. Biol. Chem. 271, 21536-21541
27. Pierce, K. L., Maudsley, S., Daaka, Y., Luttrell, L. M., and Lefkowitz, R. J., (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1489-1494
28. Bhattacharya, M., Anborgh, P. H., Babwah, A. V., Dale, L. B., Dobransky, T., Benovic, J. L., Feldman, R. D., Verdi, J. M., Rylett, R. J., and Ferguson, S. S. (2002) Nat. Cell Biol. 4, 547-555
29. Sambrano, G. R., and Coughlin, S. R. (1999) J. Biol. Chem. 274, 20178-20184
30. O'Brien, P. J., Prevost, N., Molino, M., Hollinger, M. K., Woolkalis, M. J., Woulfe, D. S., and Brass, L. F. (2000) J. Biol. Chem. 275, 13502-13509
31. Nguyen, Q. D., Faivre, S., Bruyneel, E., Rivat, C., Seto, M., Endo, T., Mareel, M., Emami, S., and Gespach, C. (2002) FASEB J. 16, 565-576
32. Hughes, P. E., Renshaw, M. W., Pfaff, M., Forsyth, J., Keivens, V. M., Schwartz, M. A., and Ginsberg, M. H. (1997) Cell 88, 521-530
33. Dery, O., Thoma, M. S., Wong, H., Grady, E. F., and Bunnett, N. W. (1999) J. Biol. Chem. 274, 18524-18535
34. Cocks, T. M., Fong, B., Chow, J. M., Anderson, G. P., Frauman, A. G., Goldie, R. G., Henry, P. J., Carr, M. J., Hamilton, J. R., and Moffatt, J. D. (1999) Nature 398, 156-160
35. D'Andrea, M. R., Derian, C. K., Santulli, R. J., and Andrade-Gordon, P. (Jun 2001) Am. J. Pathol. 158, 2031-2041
36. Macfarlane, S. R., Seatter, M. J., Kanke, T., Hunter, G. D., and Plevin, R. (2001) Pharmacol. Rev. 53, 245-282