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Volumn 66, Issue 14, 2009, Pages 2363-2381

Y-family DNA polymerases in mammalian cells

Author keywords

Mutagenesis; PCNA; Polymerase switching; Replication foci; Somatic hypermutation; Translesion DNA synthesis; Y family polymerase

Indexed keywords

CYCLINE; DNA DIRECTED DNA POLYMERASE ETA; DNA DIRECTED DNA POLYMERASE IOTA; DNA DIRECTED DNA POLYMERASE KAPPA; DNA POLYMERASE REV1; NUCLEOTIDYLTRANSFERASE; PYRIMIDINE DIMER; UNCLASSIFIED DRUG;

EID: 67650429924     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-009-0024-4     Document Type: Review
Times cited : (115)

References (192)
  • 2
    • 28844506236 scopus 로고    scopus 로고
    • Suffering in silence: The tolerance of DNA damage
    • DOI 10.1038/nrm1781
    • EC Friedberg 2005 Suffering in silence: the tolerance of DNA damage Nat Rev Mol Cell Biol 6 943 953 (Pubitemid 41778713)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.12 , pp. 943-953
    • Friedberg, E.C.1
  • 3
    • 21244506437 scopus 로고    scopus 로고
    • Eukaryotic translesion synthesis DNA polymerases: Specificity of structure and function
    • DOI 10.1146/annurev.biochem.74.082803.133250
    • S Prakash RE Johnson L Prakash 2005 Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function Annu Rev Biochem 74 317 353 (Pubitemid 40995510)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 317-353
    • Prakash, S.1    Johnson, R.E.2    Prakash, L.3
  • 7
    • 0033548231 scopus 로고    scopus 로고
    • Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta
    • RE Johnson S Prakash L Prakash 1999 Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta Science 283 1001 1004
    • (1999) Science , vol.283 , pp. 1001-1004
    • Johnson, R.E.1    Prakash, S.2    Prakash, L.3
  • 8
    • 0030735538 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism
    • JP [tmp] McDonald AS Levine R Woodgate 1997 The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism Genetics 147 1557 1568
    • (1997) Genetics , vol.147 , pp. 1557-1568
    • McDonald, J.P.1    Levine, A.S.2    Woodgate, R.3
  • 10
    • 0034726962 scopus 로고    scopus 로고
    • Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene
    • M Yuasa C Masutani T Eki F Hanaoka 2000 Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene Oncogene 19 4721 4728 (Pubitemid 30814879)
    • (2000) Oncogene , vol.19 , Issue.41 , pp. 4721-4728
    • Yuasa, M.1    Masutani, C.2    Eki, T.3    Hanaoka, F.4
  • 11
    • 0034786832 scopus 로고    scopus 로고
    • DNA polymerase η undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mrel I-dependent recombination
    • DOI 10.1002/gcc.1186
    • M Thakur M Wernick C Collins CL Limoli E Crowley JE Cleaver 2001 DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination Genes Chromosomes Cancer 32 222 235 (Pubitemid 32953976)
    • (2001) Genes Chromosomes and Cancer , vol.32 , Issue.3 , pp. 222-235
    • Thakur, M.1    Wernick, M.2    Collins, C.3    Limoli, C.L.4    Crowley, E.5    Cleaver, J.E.6
  • 12
    • 38849205431 scopus 로고    scopus 로고
    • Regulation of Saccharomyces cerevisiae DNA polymerase η transcript and protein
    • DOI 10.1007/s00411-007-0132-1
    • R Pabla D Rozario W Siede 2008 Regulation of Saccharomyces cerevisiae DNA polymerase eta transcript and protein Radiat Environ Biophys 47 157 168 (Pubitemid 351197865)
    • (2008) Radiation and Environmental Biophysics , vol.47 , Issue.1 , pp. 157-168
    • Pabla, R.1    Rozario, D.2    Siede, W.3
  • 13
    • 33846640580 scopus 로고    scopus 로고
    • Polymerase eta Is a Short-lived, Proteasomally Degraded Protein that Is Temporarily Stabilized Following UV Irradiation in Saccharomyces cerevisiae
    • DOI 10.1016/j.jmb.2006.11.093, PII S0022283606016561
    • A Skoneczna J [tmp] McIntyre M Skoneczny Z Policinska E Sledziewska-Gojska 2007 Polymerase eta is a short-lived, proteasomally degraded protein that is temporarily stabilized following UV irradiation in Saccharomyces cerevisiae J Mol Biol 366 1074 1086 (Pubitemid 46186388)
    • (2007) Journal of Molecular Biology , vol.366 , Issue.4 , pp. 1074-1086
    • Skoneczna, A.1    McIntyre, J.2    Skoneczny, M.3    Policinska, Z.4    Sledziewska-Gojska, E.5
  • 14
    • 32044449228 scopus 로고    scopus 로고
    • DNA polymerase η, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation
    • DOI 10.1128/MCB.26.4.1398-1413.2006
    • G Liu X Chen 2006 DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation Mol Cell Biol 26 1398 1413 (Pubitemid 43202565)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.4 , pp. 1398-1413
    • Liu, G.1    Chen, X.2
  • 15
    • 0036012790 scopus 로고    scopus 로고
    • Polymerase η and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation
    • DOI 10.1016/S1568-7864(01)00004-0, PII S1568786401000040
    • JE Cleaver J Bartholomew D Char E Crowley L Feeney CL Limoli 2002 Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation DNA Repair (Amst) 1 41 57 (Pubitemid 34475692)
    • (2002) DNA Repair , vol.1 , Issue.1 , pp. 41-57
    • Cleaver, J.E.1    Bartholomew, J.2    Char, D.3    Crowley, E.4    Feeney, L.5    Limoli, C.L.6
  • 17
    • 0034847259 scopus 로고    scopus 로고
    • Structure of the Catalytic Core of S. cerevisiae DNA polymerase η: Implications for translesion DNA synthesis
    • DOI 10.1016/S1097-2765(01)00306-9
    • J Trincao RE Johnson CR Escalante S Prakash L Prakash AK Aggarwal 2001 Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis Mol Cell 8 417 426 (Pubitemid 32831558)
    • (2001) Molecular Cell , vol.8 , Issue.2 , pp. 417-426
    • Trincao, J.1    Johnson, R.E.2    Escalante, C.R.3    Prakash, S.4    Prakash, L.5    Aggarwal, A.K.6
  • 18
    • 0034425754 scopus 로고    scopus 로고
    • Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η
    • DOI 10.1038/78169
    • L Haracska SL Yu RE Johnson L Prakash S Prakash 2000 Efficient and accurate replication in the presence of 7, 8-dihydro-8-oxoguanine by DNA polymerase eta Nat Genet 25 458 461 (Pubitemid 32983443)
    • (2000) Nature Genetics , vol.25 , Issue.4 , pp. 458-461
    • Haracska, L.1    Yu, S.-L.2    Johnson, R.E.3    Prakash, L.4    Prakash, S.5
  • 19
    • 34249870372 scopus 로고    scopus 로고
    • 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins
    • DOI 10.1038/nature05843, PII NATURE05843
    • G Maga G Villani E Crespan U Wimmer E Ferrari B Bertocci U Hubscher 2007 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins Nature 447 606 608 (Pubitemid 46868042)
    • (2007) Nature , vol.447 , Issue.7144 , pp. 606-608
    • Maga, G.1    Villani, G.2    Crespan, E.3    Wimmer, U.4    Ferrari, E.5    Bertocci, B.6    Hubscher, U.7
  • 20
    • 42649142912 scopus 로고    scopus 로고
    • Translesion synthesis of 7, 8-dihydro-8-oxo-2-deoxyguanosine by DNA polymerase eta in vivo
    • DH Lee GP Pfeifer 2008 Translesion synthesis of 7, 8-dihydro-8-oxo-2- deoxyguanosine by DNA polymerase eta in vivo Mutat Res 641 19 26
    • (2008) Mutat Res , vol.641 , pp. 19-26
    • Lee, D.H.1    Pfeifer, G.P.2
  • 22
    • 0037196072 scopus 로고    scopus 로고
    • Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells
    • PII S0027510702002543
    • S Avkin Z Livneh 2002 Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells Mutat Res 510 81 90 (Pubitemid 35379888)
    • (2002) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.510 , Issue.1-2 , pp. 81-90
    • Avkin, S.1    Livneh, Z.2
  • 23
    • 0034712656 scopus 로고    scopus 로고
    • Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase η
    • DOI 10.1021/bi000130k
    • A Vaisman C Masutani F Hanaoka SG Chaney 2000 Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta Biochemistry 39 4575 4580 (Pubitemid 30225320)
    • (2000) Biochemistry , vol.39 , Issue.16 , pp. 4575-4580
    • Vaisman, A.1    Masutani, C.2    Hanaoka, F.3    Chaney, S.G.4
  • 25
    • 4644298784 scopus 로고    scopus 로고
    • The role of DNA polymerase η in translesion synthesis past platinum-DNA adducts in human fibroblasts
    • DOI 10.1158/0008-5472.CAN-04-1328
    • E Bassett NM King MF Bryant S Hector L Pendyala SG Chaney M Cordeiro-Stone 2004 The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts Cancer Res 64 6469 6475 (Pubitemid 39297902)
    • (2004) Cancer Research , vol.64 , Issue.18 , pp. 6469-6475
    • Bassett, E.1    King, N.M.2    Bryant, M.F.3    Hector, S.4    Pendyala, L.5    Chaney, S.G.6    Cordeiro-Stone, M.7
  • 26
    • 0037023677 scopus 로고    scopus 로고
    • Preferential misincorporation of purine nucleotides by human DNA polymerase η opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts
    • DOI 10.1074/jbc.M112139200
    • D Chiapperino H Kroth IH Kramarczuk JM Sayer C Masutani F Hanaoka DM Jerina AM Cheh 2002 Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7, 8-diol 9, 10-epoxide deoxyguanosine adducts J Biol Chem 277 11765 11771 (Pubitemid 34952731)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.14 , pp. 11765-11771
    • Chiapperino, D.1    Kroth, H.2    Kramarczuk, I.H.3    Sayer, J.M.4    Masutani, C.5    Hanaoka, F.6    Jerina, D.M.7    Cheh, A.M.8
  • 27
    • 0037310493 scopus 로고    scopus 로고
    • Damage repair DNA polymerases Y
    • DOI 10.1016/S0959-440X(02)00003-9
    • W Yang 2003 Damage repair DNA polymerases Y Curr Opin Struct Biol 13 23 30 (Pubitemid 36170251)
    • (2003) Current Opinion in Structural Biology , vol.13 , Issue.1 , pp. 23-30
    • Yang, W.1
  • 28
    • 0035862988 scopus 로고    scopus 로고
    • Domain structure, localization, and function of DNA polymerase η, defective in xeroderma pigmentosum variant cells
    • DOI 10.1101/gad.187501
    • P Kannouche BC Broughton M Volker F Hanaoka LH Mullenders AR Lehmann 2001 Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells Genes Dev 15 158 172 (Pubitemid 32107662)
    • (2001) Genes and Development , vol.15 , Issue.2 , pp. 158-172
    • Kannouche, P.1    Broughton, B.C.2    Volker, M.3    Hanaoka, F.4    Mullenders, L.H.F.5    Lehmann, A.R.6
  • 30
    • 4544251295 scopus 로고    scopus 로고
    • Co-localization in replication foci and interaction of human Y-family members, DNA polymerase polη and REVl protein
    • DOI 10.1016/j.dnarep.2004.06.015, PII S1568786404001879
    • A Tissier P Kannouche MP Reck AR Lehmann RP Fuchs A Cordonnier 2004 Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein DNA Repair (Amst) 3 1503 1514 (Pubitemid 39221748)
    • (2004) DNA Repair , vol.3 , Issue.11 , pp. 1503-1514
    • Tissier, A.1    Kannouche, P.2    Reck, M.-P.3    Lehmann, A.R.4    Fuchs, R.P.P.5    Cordonnier, A.6
  • 32
    • 63249113718 scopus 로고    scopus 로고
    • Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells
    • (in press)
    • Akagi JI, Masutani C, Kataoka Y, Kan T, Ohashi E, Mori T, Ohmori H, Hanaoka F (2009) Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. DNA Repair (Amst) (in press)
    • (2009) DNA Repair (Amst)
    • Akagi, J.I.1    Masutani, C.2    Kataoka, Y.3    Kan, T.4    Ohashi, E.5    Mori, T.6    Ohmori, H.7    Hanaoka, F.8
  • 37
    • 2442417331 scopus 로고    scopus 로고
    • Interaction of human DNA polymerase η with monoubiquitinated PCNA: A possible mechanism for the polymerase switch in response to DNA damage
    • DOI 10.1016/S1097-2765(04)00259-X, PII S109727650400259X
    • PL Kannouche J Wing AR Lehmann 2004 Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage Mol Cell 14 491 500 (Pubitemid 38648802)
    • (2004) Molecular Cell , vol.14 , Issue.4 , pp. 491-500
    • Kannouche, P.L.1    Wing, J.2    Lehmann, A.R.3
  • 38
    • 33745581677 scopus 로고    scopus 로고
    • Controlling the subcellular localization of DNA polymerases ι and η via interactions with ubiquitin
    • DOI 10.1038/sj.emboj.7601178, PII 7601178
    • BS Plosky AE Vidal AR Fernandez de Henestrosa MP [tmp] McLenigan JP [tmp] McDonald S Mead R Woodgate 2006 Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin EMBO J 25 2847 2855 (Pubitemid 43980391)
    • (2006) EMBO Journal , vol.25 , Issue.12 , pp. 2847-2855
    • Plosky, B.S.1    Vidal, A.E.2    De Henestrosa, A.R.F.3    McLenigan, M.P.4    McDonald, J.P.5    Mead, S.6    Woodgate, R.7
  • 39
    • 6344288785 scopus 로고    scopus 로고
    • Rad18 guides polη to replication stalling sites through physical interaction and PCNA monoubiquitination
    • DOI 10.1038/sj.emboj.7600383
    • K Watanabe S Tateishi M Kawasuji T Tsurimoto H Inoue M Yamaizumi 2004 Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination EMBO J 23 3886 3896 (Pubitemid 39389719)
    • (2004) EMBO Journal , vol.23 , Issue.19 , pp. 3886-3896
    • Watanabe, K.1    Tateishi, S.2    Kawasuji, M.3    Tsurimoto, T.4    Inoue, H.5    Yamaizumi, M.6
  • 40
    • 33847381960 scopus 로고    scopus 로고
    • Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase η in Saccharomyces cerevisiae
    • DOI 10.1093/nar/gkl1102
    • JL Parker AB Bielen I Dikic HD Ulrich 2007 Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae Nucleic Acids Res 35 881 889 (Pubitemid 46344714)
    • (2007) Nucleic Acids Research , vol.35 , Issue.3 , pp. 881-889
    • Parker, J.L.1    Bielen, A.B.2    Dikic, I.3    Ulrich, H.D.4
  • 41
    • 13944256948 scopus 로고    scopus 로고
    • Ubiquitination of PCNA and the polymerase switch in human cells
    • PL Kannouche AR Lehmann 2004 Ubiquitination of PCNA and the polymerase switch in human cells Cell Cycle 3 1011 1013 (Pubitemid 40268654)
    • (2004) Cell Cycle , vol.3 , Issue.8 , pp. 1011-1013
    • Kannouche, P.L.1    Lehmann, A.R.2
  • 44
    • 33646254420 scopus 로고    scopus 로고
    • Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis
    • L Haracska I Unk L Prakash S Prakash 2006 Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis Proc Natl Acad Sci USA 103 6477 6482
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6477-6482
    • Haracska, L.1    Unk, I.2    Prakash, L.3    Prakash, S.4
  • 49
    • 55449119244 scopus 로고    scopus 로고
    • P21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
    • G Soria J Speroni OL Podhajcer C Prives V Gottifredi 2008 p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation J Cell Sci 121 3271 3282
    • (2008) J Cell Sci , vol.121 , pp. 3271-3282
    • Soria, G.1    Speroni, J.2    Podhajcer, O.L.3    Prives, C.4    Gottifredi, V.5
  • 52
    • 31544443220 scopus 로고    scopus 로고
    • Increased susceptibility to UV-induced skin carcinogenesis in polymerase η-deficient mice
    • DOI 10.1158/0008-5472.CAN-05-1862
    • Q Lin AB Clark SD [tmp] McCulloch T Yuan RT Bronson TA Kunkel R Kucherlapati 2006 Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice Cancer Res 66 87 94 (Pubitemid 43166013)
    • (2006) Cancer Research , vol.66 , Issue.1 , pp. 87-94
    • Lin, Q.1    Clark, A.B.2    McCulloch, S.D.3    Yuan, T.4    Bronson, R.T.5    Kunkel, T.A.6    Kucherlapati, R.7
  • 54
    • 30344455023 scopus 로고    scopus 로고
    • Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7
    • DOI 10.1016/j.dnarep.2005.09.009, PII S1568786405002600
    • EC Friedberg LB Meira 2006 Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7 DNA Repair (Amst) 5 189 209 (Pubitemid 43069520)
    • (2006) DNA Repair , vol.5 , Issue.2 , pp. 189-209
    • Friedberg, E.C.1    Meira, L.B.2
  • 55
    • 0015310373 scopus 로고
    • Xeroderma pigmentosum: Variants with normal DNA repair and normal sensitivity to ultraviolet light
    • JE Cleaver 1972 Xeroderma pigmentosum: variants with normal DNA repair and normal sensitivity to ultraviolet light J Invest Dermatol 58 124 128
    • (1972) J Invest Dermatol , vol.58 , pp. 124-128
    • Cleaver, J.E.1
  • 56
    • 34249941966 scopus 로고    scopus 로고
    • Translesion synthesis: Y-family polymerases and the polymerase switch
    • DOI 10.1016/j.dnarep.2007.02.003, PII S1568786407000535, Replication Fork Repair Processes
    • AR Lehmann A Niimi T Ogi S Brown S Sabbioneda JF Wing PL Kannouche CM Green 2007 Translesion synthesis: Y-family polymerases and the polymerase switch DNA Repair (Amst) 6 891 899 (Pubitemid 46880470)
    • (2007) DNA Repair , vol.6 , Issue.7 , pp. 891-899
    • Lehmann, A.R.1    Niimi, A.2    Ogi, T.3    Brown, S.4    Sabbioneda, S.5    Wing, J.F.6    Kannouche, P.L.7    Green, C.M.8
  • 57
    • 34248195087 scopus 로고    scopus 로고
    • Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase η, DNA polymerase ι causes the very high frequency and unique spectrum of UV-induced mutations
    • DOI 10.1158/0008-5472.CAN-06-3073
    • Y Wang R Woodgate TP [tmp] McManus S Mead JJ [tmp] McCormick VM Maher 2007 Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations Cancer Res 67 3018 3026 (Pubitemid 46724838)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3018-3026
    • Wang, Y.1    Woodgate, R.2    McManus, T.P.3    Mead, S.4    McCormick, J.J.5    Maher, V.M.6
  • 59
    • 0034596992 scopus 로고    scopus 로고
    • Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase ι
    • A Tissier EG Frank JP [tmp] McDonald S Iwai F Hanaoka R Woodgate 2000 Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota EMBO J 19 5259 5266 (Pubitemid 30765264)
    • (2000) EMBO Journal , vol.19 , Issue.19 , pp. 5259-5266
    • Tissier, A.1    Frank, E.G.2    Mcdonald, J.P.3    Iwai, S.4    Hanaoka, F.5    Woodgate, R.6
  • 60
    • 27744483444 scopus 로고    scopus 로고
    • The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation
    • DOI 10.1038/sj.emboj.7600833, PII 7600833
    • H Zan N Shima Z Xu A Al-Qahtani AJ Evinger Iii Y Zhong JC Schimenti P Casali 2005 The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation EMBO J 24 3757 3769 (Pubitemid 41581692)
    • (2005) EMBO Journal , vol.24 , Issue.21 , pp. 3757-3769
    • Zan, H.1    Shima, N.2    Xu, Z.3    Al-Qahtani, A.4    Evinger III, A.J.5    Zhong, Y.6    Schimenti, J.C.7    Casali, P.8
  • 62
    • 0035005241 scopus 로고    scopus 로고
    • The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation
    • DOI 10.1016/S1074-7613(01)00142-X
    • H Zan A Komori Z Li A Cerutti A Schaffer MF Flajnik M Diaz P Casali 2001 The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation Immunity 14 643 653 (Pubitemid 32520874)
    • (2001) Immunity , vol.14 , Issue.5 , pp. 643-653
    • Zan, H.1    Komori, A.2    Li, Z.3    Cerutti, A.4    Schaffer, A.5    Flajnik, M.F.6    Diaz, M.7    Casali, P.8
  • 63
    • 0035377269 scopus 로고    scopus 로고
    • DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
    • DOI 10.1038/88740
    • X Zeng DB Winter C Kasmer KH Kraemer AR Lehmann PJ Gearhart 2001 DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes Nat Immunol 2 537 541 (Pubitemid 33705856)
    • (2001) Nature Immunology , vol.2 , Issue.6 , pp. 537-541
    • Zeng, X.1    Winter, D.B.2    Kasmer, C.3    Kraemer, K.H.4    Lehmann, A.R.5    Gearhart, P.J.6
  • 65
    • 33846404877 scopus 로고    scopus 로고
    • DNA polymerase η is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse
    • DOI 10.1084/jem.20062131
    • F Delbos S Aoufouchi A Faili JC Weill CA Reynaud 2007 DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse J Exp Med 204 17 23 (Pubitemid 46148751)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.1 , pp. 17-23
    • Delbos, F.1    Aoufouchi, S.2    Faili, A.3    Weill, J.-C.4    Reynaud, C.-A.5
  • 66
    • 2642534271 scopus 로고    scopus 로고
    • DNA polymerase-η as a reverse transcriptase: Implications for mechanisms of hypermutation in innate anti-retroviral defences and antibody SHM systems
    • DOI 10.1016/j.dnarep.2004.03.040, PII S1568786404001120
    • EJ Steele 2004 DNA polymerase-eta as a reverse transcriptase: implications for mechanisms of hypermutation in innate anti-retroviral defences and antibody SHM systems DNA Repair (Amst) 3 687 692 (Pubitemid 38716097)
    • (2004) DNA Repair , vol.3 , Issue.7 , pp. 687-692
    • Steele, E.J.1
  • 68
    • 28444470501 scopus 로고    scopus 로고
    • Human DNA polymerase η promotes DNA synthesis from strand invasion intermediates of homologous recombination
    • DOI 10.1016/j.molcel.2005.10.001, PII S1097276505016710
    • MJ [tmp] McIlwraith A Vaisman Y Liu E Fanning R Woodgate SC West 2005 Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination Mol Cell 20 783 792 (Pubitemid 41740699)
    • (2005) Molecular Cell , vol.20 , Issue.5 , pp. 783-792
    • Mcllwraith, M.J.1    Vaisman, A.2    Liu, Y.3    Fanning, E.4    Woodgate, R.5    West, S.C.6
  • 75
    • 9144258471 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase
    • DOI 10.1074/jbc.M406511200
    • AE Vidal P Kannouche VN Podust W Yang AR Lehmann R Woodgate 2004 Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota J Biol Chem 279 48360 48368 (Pubitemid 39540992)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.46 , pp. 48360-48368
    • Vidal, A.E.1    Kannouche, P.2    Podust, V.N.3    Yang, W.4    Lehmann, A.R.5    Woodgate, R.6
  • 76
    • 0035355203 scopus 로고    scopus 로고
    • Altered nucleotide misinsertion fidelity associated with polι-dependent replication at the end of a DNA template
    • DOI 10.1093/emboj/20.11.2914
    • EG Frank A Tissier JP [tmp] McDonald V Rapic-Otrin X Zeng PJ Gearhart R Woodgate 2001 Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template EMBO J 20 2914 2922 (Pubitemid 32938574)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2914-2922
    • Frank, E.G.1    Tissier, A.2    McDonald, J.P.3    Rapic-Otrin, V.4    Zeng, X.5    Gearhart, P.J.6    Woodgate, R.7
  • 78
    • 0038670767 scopus 로고    scopus 로고
    • Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: Detection of polymorphisms in the Poli gene as a candidate for Par2
    • DOI 10.1038/sj.onc.1206387
    • GH Lee H Nishimori Y Sasaki H Matsushita T Kitagawa T Tokino 2003 Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2 Oncogene 22 2374 2382 (Pubitemid 36566792)
    • (2003) Oncogene , vol.22 , Issue.15 , pp. 2374-2382
    • Lee, G.-H.1    Nishimori, H.2    Sasaki, Y.3    Matsushita, H.4    Kitagawa, T.5    Tokino, T.6
  • 79
    • 0033830464 scopus 로고    scopus 로고
    • Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota
    • Y Zhang F Yuan X Wu Z Wang 2000 Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota Mol Cell Biol 20 7099 7108
    • (2000) Mol Cell Biol , vol.20 , pp. 7099-7108
    • Zhang, Y.1    Yuan, F.2    Wu, X.3    Wang, Z.4
  • 80
    • 0034738983 scopus 로고    scopus 로고
    • Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions
    • DOI 10.1038/35023030
    • RE Johnson MT Washington L Haracska S Prakash L Prakash 2000 Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions Nature 406 1015 1019 (Pubitemid 30690470)
    • (2000) Nature , vol.406 , Issue.6799 , pp. 1015-1019
    • Johnson, R.E.1    Washington, M.T.2    Haracska, L.3    Prakash, S.4    Prakash, L.5
  • 81
    • 3142674288 scopus 로고    scopus 로고
    • Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing
    • DOI 10.1038/nature02692
    • DT Nair RE Johnson S Prakash L Prakash AK Aggarwal 2004 Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing Nature 430 377 380 (Pubitemid 38937748)
    • (2004) Nature , vol.430 , Issue.6997 , pp. 377-380
    • Hair, D.T.1    Johnson, R.E.2    Prakash, S.3    Prakash, L.4    Aggarwal, A.K.5
  • 83
    • 33646492746 scopus 로고    scopus 로고
    • An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site
    • DT Nair RE Johnson L Prakash S Prakash AK Aggarwal 2006 An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site Structure 14 749 755
    • (2006) Structure , vol.14 , pp. 749-755
    • Nair, D.T.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4    Aggarwal, A.K.5
  • 84
    • 0036682979 scopus 로고    scopus 로고
    • Translesion DNA synthesis in eukaryotes: A one- or two-polymerase affair
    • DOI 10.1101/gad.1009802
    • S Prakash L Prakash 2002 Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair Genes Dev 16 1872 1883 (Pubitemid 34832917)
    • (2002) Genes and Development , vol.16 , Issue.15 , pp. 1872-1883
    • Prakash, S.1    Prakash, L.2
  • 85
    • 12844271626 scopus 로고    scopus 로고
    • A single domain in human DNA polymerase ι mediates interaction with PCNA: Implications for translesion DNA synthesis
    • DOI 10.1128/MCB.25.3.1183-1190.2005
    • L Haracska N Acharya I Unk RE Johnson J Hurwitz L Prakash S Prakash 2005 A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis Mol Cell Biol 25 1183 1190 (Pubitemid 40165823)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.3 , pp. 1183-1190
    • Haracska, L.1    Acharya, N.2    Unk, I.3    Johnson, R.E.4    Hurwitz, J.5    Prakash, L.6    Prakash, S.7
  • 87
    • 19444383801 scopus 로고    scopus 로고
    • Trading Places: How do DNA polymerases switch during translesion DNA synthesis?
    • DOI 10.1016/j.molcel.2005.03.032, PII S1097276505012761
    • EC Friedberg AR Lehmann RP Fuchs 2005 Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell 18 499 505 (Pubitemid 40726227)
    • (2005) Molecular Cell , vol.18 , Issue.5 , pp. 499-505
    • Friedberg, E.C.1    Lehmann, A.R.2    Fuchs, R.P.P.3
  • 89
    • 4143081674 scopus 로고    scopus 로고
    • Altered DNA polymerase ι expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis
    • DOI 10.1158/0008-5472.CAN-04-0603
    • J Yang Z Chen Y Liu RJ Hickey LH Malkas 2004 Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis Cancer Res 64 5597 5607 (Pubitemid 39095555)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5597-5607
    • Yang, J.1    Chen, Z.2    Liu, Y.3    Hickey, R.J.4    Malkas, L.H.5
  • 90
    • 21244487080 scopus 로고    scopus 로고
    • Genetic linkage between Polι deficiency and increased susceptibility to lung tumors in mice
    • DOI 10.1111/j.1349-7006.2005.00042.x
    • GH Lee H Matsushita 2005 Genetic linkage between Pol iota deficiency and increased susceptibility to lung tumors in mice Cancer Sci 96 256 259 (Pubitemid 40895072)
    • (2005) Cancer Science , vol.96 , Issue.5 , pp. 256-259
    • Lee, G.-H.1    Matsushita, H.2
  • 91
    • 0037206851 scopus 로고    scopus 로고
    • Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota
    • DOI 10.1038/nature01117
    • A Faili S Aoufouchi E Flatter Q Gueranger CA Reynaud JC Weill 2002 Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota Nature 419 944 947 (Pubitemid 35339630)
    • (2002) Nature , vol.419 , Issue.6910 , pp. 944-947
    • Faili, A.1    Aoufouchi, S.2    Flatter, E.3    Gueranger, Q.4    Reynaud, C.-A.5    Weill, J.-C.6
  • 93
    • 18044383922 scopus 로고    scopus 로고
    • Normal immunoglobulin gene somatic hypermutation in Polκ-Polι double-deficient mice
    • DOI 10.1016/j.imlet.2004.11.022
    • T Shimizu T Azuma M Ishiguro N Kanjo S Yamada H Ohmori 2005 Normal immunoglobulin gene somatic hypermutation in Pol kappa-Pol iota double-deficient mice Immunol Lett 98 259 264 (Pubitemid 40602638)
    • (2005) Immunology Letters , vol.98 , Issue.2 , pp. 259-264
    • Shimizu, T.1    Azuma, T.2    Ishiguro, M.3    Kanjo, N.4    Yamada, S.5    Ohmori, H.6
  • 94
    • 0035890302 scopus 로고    scopus 로고
    • Unique misinsertion specificity of poι may decrease the mutagenic potential of deaminated cytosines
    • DOI 10.1093/emboj/20.22.6520
    • A Vaisman R Woodgate 2001 Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines EMBO J 20 6520 6529 (Pubitemid 33078724)
    • (2001) EMBO Journal , vol.20 , Issue.22 , pp. 6520-6529
    • Vaisman, A.1    Woodgate, R.2
  • 100
    • 10044266718 scopus 로고    scopus 로고
    • Cellular functions of DNA polymerase ζ and REV1 protein
    • DOI 10.1016/S0065-3233(04)69006-1, PII S0065323304690061, DNA Repair and Replication
    • CW Lawrence 2004 Cellular functions of DNA polymerase zeta and Rev1 protein Adv Protein Chem 69 167 203 (Pubitemid 39600960)
    • (2004) Advances in Protein Chemistry , vol.69 , pp. 167-203
    • Lawrence, C.W.1
  • 102
    • 0037150492 scopus 로고    scopus 로고
    • Cellular roles of DNA polymerase ζ and Rev1 protein
    • DOI 10.1016/S1568-7864(02)00038-1, PII S1568786402000381
    • CW Lawrence 2002 Cellular roles of DNA polymerase zeta and Rev1 protein DNA Repair (Amst) 1 425 435 (Pubitemid 34615693)
    • (2002) DNA Repair , vol.1 , Issue.6 , pp. 425-435
    • Lawrence, C.W.1
  • 103
    • 0033571521 scopus 로고    scopus 로고
    • The human REV1 gene codes for a DNA template-dependent dCMP transferase
    • DOI 10.1093/nar/27.22.4468
    • W Lin H Xin Y Zhang X Wu F Yuan Z Wang 1999 The human REV1 gene codes for a DNA template-dependent dCMP transferase Nucleic Acids Res 27 4468 4475 (Pubitemid 29533189)
    • (1999) Nucleic Acids Research , vol.27 , Issue.22 , pp. 4468-4475
    • Lin, W.1    Xin, H.2    Zhang, Y.3    Wu, X.4    Yuan, F.5    Wang, Z.6
  • 104
  • 105
    • 0035805485 scopus 로고    scopus 로고
    • Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain
    • Y Masuda M Takahashi N Tsunekuni T Minami M Sumii K Miyagawa K Kamiya 2001 Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain J Biol Chem 276 15051 15058
    • (2001) J Biol Chem , vol.276 , pp. 15051-15058
    • Masuda, Y.1    Takahashi, M.2    Tsunekuni, N.3    Minami, T.4    Sumii, M.5    Miyagawa, K.6    Kamiya, K.7
  • 108
    • 33845801753 scopus 로고    scopus 로고
    • Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1
    • DOI 10.1016/j.dnarep.2006.09.002, PII S1568786406002825
    • S Sabbioneda I Bortolomai M Giannattasio P Plevani M Muzi-Falconi 2007 Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1 DNA Repair (Amst) 6 121 127 (Pubitemid 46014549)
    • (2007) DNA Repair , vol.6 , Issue.1 , pp. 121-127
    • Sabbioneda, S.1    Bortolomai, I.2    Giannattasio, M.3    Plevani, P.4    Muzi-Falconi, M.5
  • 109
    • 25844440534 scopus 로고    scopus 로고
    • Biochemistry: Rev1 employs a novel mechanism of DNA synthesis using a protein template
    • DOI 10.1126/science.1116336
    • DT Nair RE Johnson L Prakash S Prakash AK Aggarwal 2005 Rev1 employs a novel mechanism of DNA synthesis using a protein template Science 309 2219 2222 (Pubitemid 41396072)
    • (2005) Science , vol.309 , Issue.5744 , pp. 2219-2222
    • Nair, D.T.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4    Aggarwal, A.K.5
  • 110
    • 33747674256 scopus 로고    scopus 로고
    • Role of single-stranded DNA in targeting REV1 to primer termini
    • DOI 10.1074/jbc.M602967200
    • Y Masuda K Kamiya 2006 Role of single-stranded DNA in targeting REV1 to primer termini J Biol Chem 281 24314 24321 (Pubitemid 44274204)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.34 , pp. 24314-24321
    • Masuda, Y.1    Kamiya, K.2
  • 114
    • 33746162368 scopus 로고    scopus 로고
    • REV1 Protein Interacts with PCNA: Significance of the REV1 BRCT Domain In Vitro and In Vivo
    • DOI 10.1016/j.molcel.2006.05.038, PII S1097276506003807
    • C Guo E Sonoda TS Tang JL Parker AB Bielen S Takeda HD Ulrich EC Friedberg 2006 REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo Mol Cell 23 265 271 (Pubitemid 44081878)
    • (2006) Molecular Cell , vol.23 , Issue.2 , pp. 265-271
    • Guo, C.1    Sonoda, E.2    Tang, T.-S.3    Parker, J.L.4    Bielen, A.B.5    Takeda, S.6    Ulrich, H.D.7    Friedberg, E.C.8
  • 116
    • 34547117417 scopus 로고    scopus 로고
    • A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage
    • DOI 10.1074/jbc.M702366200
    • A Wood P Garg PM Burgers 2007 A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage J Biol Chem 282 20256 20263 (Pubitemid 47099980)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20256-20263
    • Wood, A.1    Garg, P.2    Burgers, P.M.J.3
  • 117
    • 14844362615 scopus 로고    scopus 로고
    • Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1
    • DOI 10.1093/nar/gki279
    • AL Ross LJ Simpson JE Sale 2005 Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1 Nucleic Acids Res 33 1280 1289 (Pubitemid 41439921)
    • (2005) Nucleic Acids Research , vol.33 , Issue.4 , pp. 1280-1289
    • Ross, A.-L.1    Simpson, L.J.2    Sale, J.E.3
  • 118
    • 48149104225 scopus 로고    scopus 로고
    • Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance
    • S D'Souza LS Waters GC Walker 2008 Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance DNA Repair (Amst) 7 1455 1470
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1455-1470
    • D'Souza, S.1    Waters, L.S.2    Walker, G.C.3
  • 119
    • 0038823615 scopus 로고    scopus 로고
    • Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins
    • DOI 10.1074/jbc.M211765200
    • Y Masuda M Ohmae K Masuda K Kamiya 2003 Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins J Biol Chem 278 12356 12360 (Pubitemid 36800219)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 12356-12360
    • Masuda, Y.1    Ohmae, M.2    Masuda, K.3    Kamiya, K.4
  • 120
    • 33745253465 scopus 로고    scopus 로고
    • A human DNA polymerase η complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest
    • DOI 10.1111/j.1365-2443.2006.00974.x
    • MS Yuasa C Masutani A Hirano MA Cohn M Yamaizumi Y Nakatani F Hanaoka 2006 A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest Genes Cells 11 731 744 (Pubitemid 43923345)
    • (2006) Genes to Cells , vol.11 , Issue.7 , pp. 731-744
    • Yuasa, M.S.1    Masutani, C.2    Hirano, A.3    Cohn, M.A.4    Yamaizumi, M.5    Nakatani, Y.6    Hanaoka, F.7
  • 122
    • 10244232940 scopus 로고    scopus 로고
    • REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide
    • DOI 10.1093/nar/gkh903
    • S Mukhopadhyay DR Clark NB Watson W Zacharias WG [tmp] McGregor 2004 REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide Nucleic Acids Res 32 5820 5826 (Pubitemid 39619164)
    • (2004) Nucleic Acids Research , vol.32 , Issue.19 , pp. 5820-5826
    • Mukhopadyay, S.1    Clark, D.R.2    Watson, N.B.3    Zacharias, W.4    McGregor, W.G.5
  • 123
    • 4344597147 scopus 로고    scopus 로고
    • The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair
    • DOI 10.1016/j.molcel.2004.08.009, PII S1097276504004502
    • W Niedzwiedz G Mosedale M Johnson CY Ong P Pace KJ Patel 2004 The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair Mol Cell 15 607 620 (Pubitemid 39141787)
    • (2004) Molecular Cell , vol.15 , Issue.4 , pp. 607-620
    • Niedzwiedz, W.1    Mosedale, G.2    Johnson, M.3    Ong, C.Y.4    Pace, P.5    Patel, K.J.6
  • 124
    • 43849098620 scopus 로고    scopus 로고
    • The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly
    • KD Mirchandani RM [tmp] McCaffrey AD D'Andrea 2008 The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly DNA Repair (Amst) 7 902 911
    • (2008) DNA Repair (Amst) , vol.7 , pp. 902-911
    • Mirchandani, K.D.1    McCaffrey, R.M.2    D'Andrea, A.D.3
  • 125
    • 57149145779 scopus 로고    scopus 로고
    • REV1 restrains DNA polymerase {zeta} to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo
    • Szuts D, Marcus AP, Himoto M, Iwai S, Sale JE (2008) REV1 restrains DNA polymerase {zeta} to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Nucleic Acids Res 36:6767-6780
    • (2008) Nucleic Acids Res , vol.36 , pp. 6767-6780
    • Szuts, D.1    Marcus, A.P.2    Himoto, M.3    Iwai, S.4    Sale, J.E.5
  • 126
    • 0344875492 scopus 로고    scopus 로고
    • Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene
    • DOI 10.1093/nar/gkg725
    • DR Clark W Zacharias L Panaitescu WG [tmp] McGregor 2003 Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene Nucleic Acids Res 31 4981 4988 (Pubitemid 37441864)
    • (2003) Nucleic Acids Research , vol.31 , Issue.17 , pp. 4981-4988
    • Clark, D.R.1    Zacharias, W.2    Panaitescu, L.3    McGregor, W.G.4
  • 128
    • 24944540730 scopus 로고    scopus 로고
    • REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast
    • DOI 10.1016/j.dnarep.2005.05.002, PII S1568786405001138
    • Poltoratsky V, Horton JK, Prasad R, Wilson SH (2005) REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. DNA Repair (Amst) 4:1182-1188 (Pubitemid 41316595)
    • (2005) DNA Repair , vol.4 , Issue.10 , pp. 1182-1188
    • Poltoratsky, V.1    Horton, J.K.2    Prasad, R.3    Wilson, S.H.4
  • 129
    • 0037388452 scopus 로고    scopus 로고
    • Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line
    • DOI 10.1093/emboj/cdg161
    • LJ Simpson JE Sale 2003 Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line EMBO J 22 1654 1664 (Pubitemid 36417413)
    • (2003) EMBO Journal , vol.22 , Issue.7 , pp. 1654-1664
    • Simpson, L.J.1    Sale, J.E.2
  • 133
    • 44449153036 scopus 로고    scopus 로고
    • REV1 genetic variants associated with the risk of cervical carcinoma
    • X He F Ye J Zhang Q Cheng J Shen H Chen 2008 REV1 genetic variants associated with the risk of cervical carcinoma Eur J Epidemiol 23 403 409
    • (2008) Eur J Epidemiol , vol.23 , pp. 403-409
    • He, X.1    Ye, F.2    Zhang, J.3    Cheng, Q.4    Shen, J.5    Chen, H.6
  • 134
    • 4143116647 scopus 로고    scopus 로고
    • Crystal structure of the catalytic core of human DNA polymerase kappa
    • DOI 10.1016/j.str.2004.05.011, PII S0969212604002138
    • SN Uljon RE Johnson TA Edwards S Prakash L Prakash AK Aggarwal 2004 Crystal structure of the catalytic core of human DNA polymerase kappa Structure (Camb) 12 1395 1404 (Pubitemid 39092084)
    • (2004) Structure , vol.12 , Issue.8 , pp. 1395-1404
    • Uljon, S.N.1    Johnson, R.E.2    Edwards, T.A.3    Prakash, S.4    Prakash, L.5    Aggarwal, A.K.6
  • 135
    • 34147135142 scopus 로고    scopus 로고
    • Proficient and accurate bypass of persistent DNA lesions by DinB DNA polymerases
    • DF Jarosz VG Godoy GC Walker 2007 Proficient and accurate bypass of persistent DNA lesions by DinB DNA polymerases Cell Cycle 6 817 822 (Pubitemid 46572622)
    • (2007) Cell Cycle , vol.6 , Issue.7 , pp. 817-822
    • Jarosz, D.F.1    Godoy, V.G.2    Walker, G.C.3
  • 137
    • 0033387531 scopus 로고    scopus 로고
    • Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein DinB
    • T Ogi T Kato Jr T Kato H Ohmori 1999 Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB Genes Cells 4 607 618 (Pubitemid 30043542)
    • (1999) Genes to Cells , vol.4 , Issue.11 , pp. 607-618
    • Ogi, T.1    Kato Jr., T.2    Kato, T.3    Ohmori, H.4
  • 139
    • 12344250588 scopus 로고    scopus 로고
    • Multiple PolK (POLK) transcripts in mammalian testis
    • DOI 10.1016/j.dnarep.2004.10.006, PII S1568786404003131
    • C Guo T Gao N Confer S Velasco-Miguel EC Friedberg 2005 Multiple PolK (POLK) transcripts in mammalian testis DNA Repair (Amst) 4 397 402 (Pubitemid 40127003)
    • (2005) DNA Repair , vol.4 , Issue.3 , pp. 397-402
    • Guo, C.1    Gao, T.2    Confer, N.3    Velasco-Miguel, S.4    Friedberg, E.C.5
  • 140
    • 0035179083 scopus 로고    scopus 로고
    • Expression of human and mouse genes encoding polκ: Testis-specific developmental regulation and AhR-dependent inducible transcription
    • DOI 10.1046/j.1365-2443.2001.00478.x
    • T Ogi J Mimura M Hikida H Fujimoto Y Fujii-Kuriyama H Ohmori 2001 Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription Genes Cells 6 943 953 (Pubitemid 33100029)
    • (2001) Genes to Cells , vol.6 , Issue.11 , pp. 943-953
    • Ogi, T.1    Mimura, J.2    Hikida, M.3    Fujimoto, H.4    Fujii-Kuriyama, Y.5    Ohmori, H.6
  • 141
    • 34249021158 scopus 로고    scopus 로고
    • Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase κ in colorectal cancer
    • DOI 10.1038/sj.onc.1210116, PII 1210116
    • F Lemee C Bavoux MJ Pillaire A Bieth CR Machado SD Pena R Guimbaud J Selves JS Hoffmann C Cazaux 2007 Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer Oncogene 26 3387 3394 (Pubitemid 46788878)
    • (2007) Oncogene , vol.26 , Issue.23 , pp. 3387-3394
    • Lemee, F.1    Bavoux, C.2    Pillaire, M.J.3    Bieth, A.4    Machado, C.R.5    Pena, S.D.6    Guimbaud, R.7    Selves, J.8    Hoffmann, J.S.9    Cazaux, C.10
  • 142
    • 41949130152 scopus 로고    scopus 로고
    • Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance
    • C Guo TS Tang M Bienko I Dikic EC Friedberg 2008 Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance J Biol Chem 283 4658 4664
    • (2008) J Biol Chem , vol.283 , pp. 4658-4664
    • Guo, C.1    Tang, T.S.2    Bienko, M.3    Dikic, I.4    Friedberg, E.C.5
  • 144
    • 0035808417 scopus 로고    scopus 로고
    • Purification and characterization of polκ, a DNA polymerase encoded by the human DINB1 gene
    • DOI 10.1074/jbc.M004413200
    • VL Gerlach WJ Feaver PL Fischhaber EC Friedberg 2001 Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene J Biol Chem 276 92 98 (Pubitemid 32050293)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.1 , pp. 92-98
    • Gerlach, V.L.1    Feaver, W.J.2    Fischhaber, P.L.3    Friedberg, E.C.4
  • 147
    • 2442661622 scopus 로고    scopus 로고
    • Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases η and κ
    • DOI 10.1021/bi0360298
    • N Suzuki S Itoh K Poon C Masutani F Hanaoka H Ohmori I Yoshizawa S Shibutani 2004 Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa Biochemistry 43 6304 6311 (Pubitemid 38669497)
    • (2004) Biochemistry , vol.43 , Issue.20 , pp. 6304-6311
    • Suzuki, N.1    Itoh, S.2    Poon, K.3    Masutani, C.4    Hanaoka, F.5    Ohmori, H.6    Yoshizawa, I.7    Shibutani, S.8
  • 148
    • 0037020269 scopus 로고    scopus 로고
    • Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides
    • PL Fischhaber VL Gerlach WJ Feaver Z Hatahet SS Wallace EC Friedberg 2002 Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides J Biol Chem 277 37604 37611
    • (2002) J Biol Chem , vol.277 , pp. 37604-37611
    • Fischhaber, P.L.1    Gerlach, V.L.2    Feaver, W.J.3    Hatahet, Z.4    Wallace, S.S.5    Friedberg, E.C.6
  • 150
    • 33744789415 scopus 로고    scopus 로고
    • The Y-family DNA polymerase κ (pol κ) functions in mammalian nucleotide-excision repair
    • DOI 10.1038/ncb1417, PII N1417
    • T Ogi AR Lehmann 2006 The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair Nat Cell Biol 8 640 642 (Pubitemid 43827358)
    • (2006) Nature Cell Biology , vol.8 , Issue.6 , pp. 640-642
    • Ogi, T.1    Lehmann, A.R.2
  • 152
    • 4143116647 scopus 로고    scopus 로고
    • Crystal structure of the catalytic core of human DNA polymerase kappa
    • DOI 10.1016/j.str.2004.05.011, PII S0969212604002138
    • SN Uljon RE Johnson TA Edwards S Prakash L Prakash AK Aggarwal 2004 Crystal structure of the catalytic core of human DNA polymerase kappa Structure 12 1395 1404 (Pubitemid 39092084)
    • (2004) Structure , vol.12 , Issue.8 , pp. 1395-1404
    • Uljon, S.N.1    Johnson, R.E.2    Edwards, T.A.3    Prakash, S.4    Prakash, L.5    Aggarwal, A.K.6
  • 153
    • 33646234739 scopus 로고    scopus 로고
    • Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest
    • X Bi LR Barkley DM Slater S Tateishi M Yamaizumi H Ohmori C Vaziri 2006 Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest Mol Cell Biol 26 3527 3540
    • (2006) Mol Cell Biol , vol.26 , pp. 3527-3540
    • Bi, X.1    Barkley, L.R.2    Slater, D.M.3    Tateishi, S.4    Yamaizumi, M.5    Ohmori, H.6    Vaziri, C.7
  • 154
    • 14044272631 scopus 로고    scopus 로고
    • Localisation of human Y-family DNA polymerase κ: Relationship to PCNA foci
    • DOI 10.1242/jcs.01603
    • T Ogi P Kannouche AR Lehmann 2005 Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci J Cell Sci 118 129 136 (Pubitemid 40277111)
    • (2005) Journal of Cell Science , vol.118 , Issue.1 , pp. 129-136
    • Ogi, T.1    Kannouche, P.2    Lehmann, A.R.3
  • 156
    • 20444437200 scopus 로고    scopus 로고
    • DNA polymerase κ is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint
    • DOI 10.1074/jbc.M501562200
    • X Bi DM Slater H Ohmori C Vaziri 2005 DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint J Biol Chem 280 22343 22355 (Pubitemid 40827891)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 22343-22355
    • Bi, X.1    Slater, D.M.2    Ohmori, H.3    Vaziri, C.4
  • 160
    • 11144237897 scopus 로고    scopus 로고
    • Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: The role of DNA polymerase
    • DOI 10.1074/jbc.M409155200
    • S Avkin M Goldsmith S Velasco-Miguel N Geacintov EC Friedberg Z Livneh 2004 Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa J Biol Chem 279 53298 53305 (Pubitemid 40051834)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.51 , pp. 53298-53305
    • Avkin, S.1    Goldsmith, M.2    Velasco-Miguel, S.3    Geacintov, N.4    Friedberg, E.C.5    Livneh, Z.6
  • 163
    • 0035879009 scopus 로고    scopus 로고
    • DNA polymerase κ, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer
    • J O-Wang K Kawamura Y Tada H Ohmori H Kimura S Sakiyama M Tagawa 2001 DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer Cancer Res 61 5366 5369 (Pubitemid 32694911)
    • (2001) Cancer Research , vol.61 , Issue.14 , pp. 5366-5369
    • O-Wang, J.1    Kawamura, K.2    Tada, Y.3    Ohmori, H.4    Kimura, H.5    Sakiyama, S.6    Tagawa, M.7
  • 164
    • 21244433058 scopus 로고    scopus 로고
    • Adaptation to DNA damage and stimulation of genetic instability: The double-edged sword mammalian DNA polymerase κ
    • DOI 10.1016/j.biochi.2005.02.007, PII S0300908405000453, Biological Responses to DNA Damage
    • C Bavoux JS Hoffmann C Cazaux 2005 Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa Biochimie 87 637 646 (Pubitemid 40884626)
    • (2005) Biochimie , vol.87 , Issue.7 , pp. 637-646
    • Bavoux, C.1    Hoffmann, J.S.2    Cazaux, C.3
  • 165
    • 0037068455 scopus 로고    scopus 로고
    • RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
    • DOI 10.1038/nature00991
    • C Hoege B Pfander GL Moldovan G Pyrowolakis S Jentsch 2002 RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO Nature 419 135 141 (Pubitemid 35025438)
    • (2002) Nature , vol.419 , Issue.6903 , pp. 135-141
    • Hoege, C.1    Pfander, B.2    Moldovan, G.-L.3    Pyrowolakis, G.4    Jentsch, S.5
  • 166
    • 0141831006 scopus 로고    scopus 로고
    • Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
    • DOI 10.1038/nature01965
    • P Stelter HD Ulrich 2003 Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation Nature 425 188 191 (Pubitemid 37150898)
    • (2003) Nature , vol.425 , Issue.6954 , pp. 188-191
    • Stelter, P.1    Ulrich, H.D.2
  • 168
    • 40649097306 scopus 로고    scopus 로고
    • Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a
    • AA Davies D Huttner Y Daigaku S Chen HD Ulrich 2008 Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a Mol Cell 29 625 636
    • (2008) Mol Cell , vol.29 , pp. 625-636
    • Davies, A.A.1    Huttner, D.2    Daigaku, Y.3    Chen, S.4    Ulrich, H.D.5
  • 169
    • 33845959940 scopus 로고    scopus 로고
    • Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities
    • DOI 10.1074/jbc.M606799200
    • DJ Chang PJ Lupardus KA Cimprich 2006 Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities J Biol Chem 281 32081 32088 (Pubitemid 46036762)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.43 , pp. 32081-32088
    • Chang, D.J.1    Lupardus, P.J.2    Cimprich, K.A.3
  • 171
    • 33646156444 scopus 로고    scopus 로고
    • Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation
    • DOI 10.1038/sj.onc.1209315, PII 1209315
    • G Soria O Podhajcer C Prives V Gottifredi 2006 P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation Oncogene 25 2829 2838 (Pubitemid 43739233)
    • (2006) Oncogene , vol.25 , Issue.20 , pp. 2829-2838
    • Soria, G.1    Podhajcer, O.2    Prives, C.3    Gottifredi, V.4
  • 172
    • 42249095624 scopus 로고    scopus 로고
    • PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage
    • T Gohler IM Munoz J Rouse JJ Blow 2008 PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage DNA Repair (Amst) 7 775 787
    • (2008) DNA Repair (Amst) , vol.7 , pp. 775-787
    • Gohler, T.1    Munoz, I.M.2    Rouse, J.3    Blow, J.J.4
  • 173
    • 43249094413 scopus 로고    scopus 로고
    • Chk1 and claspin potentiate PCNA ubiquitination
    • DOI 10.1101/gad.1632808
    • XH Yang B Shiotani M Classon L Zou 2008 Chk1 and Claspin potentiate PCNA ubiquitination Genes Dev 22 1147 1152 (Pubitemid 351656574)
    • (2008) Genes and Development , vol.22 , Issue.9 , pp. 1147-1152
    • Yang, X.H.1    Shiotani, B.2    Classon, M.3    Zou, L.4
  • 175
    • 33750935287 scopus 로고    scopus 로고
    • Gaps and forks in DNA replication: Rediscovering old models
    • DOI 10.1016/j.dnarep.2006.07.002, PII S1568786406002151
    • AR Lehmann RP Fuchs 2006 Gaps and forks in DNA replication: rediscovering old models DNA Repair (Amst) 5 1495 1498 (Pubitemid 44739451)
    • (2006) DNA Repair , vol.5 , Issue.12 , pp. 1495-1498
    • Lehmann, A.R.1    Fuchs, R.P.2
  • 176
    • 29544437558 scopus 로고    scopus 로고
    • Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
    • DOI 10.1016/j.molcel.2005.11.015, PII S1097276505018022
    • M Lopes M Foiani JM Sogo 2006 Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions Mol Cell 21 15 27 (Pubitemid 43017845)
    • (2006) Molecular Cell , vol.21 , Issue.1 , pp. 15-27
    • Lopes, M.1    Foiani, M.2    Sogo, J.M.3
  • 179
    • 43049160831 scopus 로고    scopus 로고
    • Rad6-Rad18 Mediates a Eukaryotic SOS Response by Ubiquitinating the 9-1-1 Checkpoint Clamp
    • DOI 10.1016/j.cell.2008.02.050, PII S009286740800442X
    • Y Fu Y Zhu K Zhang M Yeung D Durocher W Xiao 2008 Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp Cell 133 601 611 (Pubitemid 351636298)
    • (2008) Cell , vol.133 , Issue.4 , pp. 601-611
    • Fu, Y.1    Zhu, Y.2    Zhang, K.3    Yeung, M.4    Durocher, D.5    Xiao, W.6
  • 181
    • 43449133259 scopus 로고    scopus 로고
    • PCNA Ubiquitination and REV1 Define Temporally Distinct Mechanisms for Controlling Translesion Synthesis in the Avian Cell Line DT40
    • DOI 10.1016/j.molcel.2008.03.024, PII S1097276508003249
    • CE Edmunds LJ Simpson JE Sale 2008 PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40 Mol Cell 30 519 529 (Pubitemid 351672376)
    • (2008) Molecular Cell , vol.30 , Issue.4 , pp. 519-529
    • Edmunds, C.E.1    Simpson, L.J.2    Sale, J.E.3
  • 182
    • 4644343886 scopus 로고    scopus 로고
    • Efficiency, fidelity and enzymatic switching during translesion DNA synthesis
    • SD [tmp] McCulloch RJ Kokoska TA Kunkel 2004 Efficiency, fidelity and enzymatic switching during translesion DNA synthesis Cell Cycle 3 580 583 (Pubitemid 40278194)
    • (2004) Cell Cycle , vol.3 , Issue.5 , pp. 580-583
    • McCulloch, S.D.1    Kokoska, R.J.2    Kunkel, T.A.3
  • 183
    • 1542287220 scopus 로고    scopus 로고
    • Preferential cis-syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity
    • DOI 10.1038/nature02352
    • SD [tmp] McCulloch RJ Kokoska C Masutani S Iwai F Hanaoka TA Kunkel 2004 Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity Nature 428 97 100 (Pubitemid 38332365)
    • (2004) Nature , vol.428 , Issue.6978 , pp. 97-100
    • McCulloch, S.D.1    Kokoska, R.J.2    Masutani, C.3    Iwai, S.4    Hanaoka, F.5    Kunkel, T.A.6
  • 184
    • 0033564917 scopus 로고    scopus 로고
    • Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
    • DOI 10.1093/emboj/18.12.3491
    • C Masutani M Araki A Yamada R Kusumoto T Nogimori T Maekawa S Iwai F Hanaoka 1999 Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity EMBO J 18 3491 3501 (Pubitemid 29276594)
    • (1999) EMBO Journal , vol.18 , Issue.12 , pp. 3491-3501
    • Masutani, C.1    Araki, M.2    Yamada, A.3    Kusumoto, R.4    Nogimori, T.5    Maekawa, T.6    Iwai, S.7    Hanaoka, F.8
  • 185
    • 0035812849 scopus 로고    scopus 로고
    • Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication
    • DOI 10.1016/S0092-8674(01)00515-3
    • H Ling F Boudsocq R Woodgate W Yang 2001 Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication Cell 107 91 102 (Pubitemid 32972040)
    • (2001) Cell , vol.107 , Issue.1 , pp. 91-102
    • Ling, H.1    Boudsocq, F.2    Woodgate, R.3    Yang, W.4
  • 186
    • 0347416710 scopus 로고    scopus 로고
    • Error-Prone DNA Polymerases: When Making a Mistake is the Only Way to Get Ahead
    • DOI 10.1146/annurev.genet.37.042203.132748
    • AJ Rattray JN Strathern 2003 Error-prone DNA polymerases: when making a mistake is the only way to get ahead Annu Rev Genet 37 31 66 (Pubitemid 38041420)
    • (2003) Annual Review of Genetics , vol.37 , pp. 31-66
    • Rattray, A.J.1    Strathern, J.N.2
  • 187
    • 57749101303 scopus 로고    scopus 로고
    • Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans
    • SH Kim WM Michael 2008 Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans Mol Cell 32 757 766
    • (2008) Mol Cell , vol.32 , pp. 757-766
    • Kim, S.H.1    Michael, W.M.2
  • 189
    • 34447572295 scopus 로고    scopus 로고
    • Translesion DNA replication proteins as molecular targets for cancer prevention
    • NB Watson S Mukhopadhyay WG [tmp] McGregor 2006 Translesion DNA replication proteins as molecular targets for cancer prevention Cancer Lett 241 13 22
    • (2006) Cancer Lett , vol.241 , pp. 13-22
    • Watson, N.B.1    Mukhopadhyay, S.2    McGregor, W.G.3
  • 191
    • 43649086471 scopus 로고    scopus 로고
    • Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells
    • DOI 10.1111/j.1349-7006.2008.00764.x
    • J Takezawa Y Ishimi K Yamada 2008 Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells Cancer Sci 99 863 871 (Pubitemid 351997586)
    • (2008) Cancer Science , vol.99 , Issue.5 , pp. 863-871
    • Takezawa, J.1    Ishimi, Y.2    Yamada, K.3
  • 192
    • 33645731673 scopus 로고    scopus 로고
    • A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling
    • NP Dantuma TA Groothuis FA Salomons J Neefjes 2006 A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling J Cell Biol 173 19 26
    • (2006) J Cell Biol , vol.173 , pp. 19-26
    • Dantuma, N.P.1    Groothuis, T.A.2    Salomons, F.A.3    Neefjes, J.4


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