A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

Journal of Cell Biology

Volumn 173, Issue 1, 2006, Pages 19-26

  Dantuma, Nico P ^a   Groothuis, Tom A M ^b   Salomons, Florian A ^a   Neefjes, Jacques ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2A; PROTEASOME; UBIQUITIN;

ARTICLE; CELL CYCLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; CYTOLOGY; GENOME ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRESS; UBIQUITINATION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL COMPARTMENTATION; CELL LINE, TUMOR; CHROMATIN ASSEMBLY AND DISASSEMBLY; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HISTONES; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; SCHIZOSACCHAROMYCES; STRESS; UBIQUITIN;

EID: 33645731673     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200510071     Document Type: Article

References (21)

1. Aguilar, R.C., and B. Wendland. 2003. Ubiquitin: not just for proteasomes anymore. Curr. Opin. Cell Biol. 15:184-190.
2. Baarends, W.M., E. Wassenaar, R. van der Laan, J. Hoogerbrugge, E. Sleddens-Linkels, J.H. Hoeijmakers, P. de Boer, and J.A. Grootegoed. 2005. Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis. Mol. Cell. Biol. 25:1041-1053.
3. Bjorkoy, G., T. Lamark, A. Brech, H. Outzen, M. Perander, A. Overvatn, H. Stenmark, and T. Johansen. 2005. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171:603-614.
4. Carlson, N., S. Rogers, and M. Rechsteiner. 1987. Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock. J. Cell Biol. 104:547-555.
5. de Napoles, M., J.E. Mermoud, R. Wakao, Y.A. Tang, M. Endoh, R. Appanah, T.B. Nesterova, J. Silva, A.P. Otte, M. Vidal, et al. 2004. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev. Cell. 7:663-676.
6. Di Fiore, P.P., S. Polo, and K. Hofmann. 2003. When ubiquitin meets ubiquitin receptors: a signalling connection. Nat. Rev. Mol. Cell Biol. 4:491-497.
7. Hershko, A., and A. Ciechanover. 1998. The ubiquitin system. Annu. Rev. Biochem. 67:425-479.
8. Hunt, L.T., and M.O. Dayhoff. 1977. Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24. Biochem. Biophys. Res. Commun. 74:650-655.
9. Kawaguchi, Y., J.J. Kovacs, A. McLaurin, J.M. Vance, A. Ito, and T.P. Yao. 2003. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell. 115:727-738.
10. Koster, M., T. Frahm, and H. Hauser. 2005. Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies. Curr. Opin. Biotechnol. 16:28-34.
11. Levinger, L., and A. Varshavsky. 1982. Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome. Cell. 28:375-385.
12. Mimnaugh, E.G., H.Y. Chen, J.R. Davie, J.E. Celis, and L. Neckers. 1997. Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription, translation, and the cellular stress response. Biochemistry. 36:14418-14429.
13. Patterson, G.H., and J. Lippincott-Schwartz. 2002. A photoactivatable GFP for selective photolabeling of proteins and cells. Science. 297:1873-1877.
14. Pickart, C.M. 2001. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70:503-533.
15. Qian, S.B., D.E. Ott, U. Schubert, J.R. Bennink, and J.W. Yewdell. 2002. Fusion proteins with COOH-terminal ubiquitin are stable and maintain dual functionality in vivo. J. Biol. Chem. 277:38818-38826.
16. Reits, E.A., and J.J. Neefjes. 2001. From fixed to FRAP: measuring protein mobility and activity in living cells. Nat. Cell Biol. 3:E145-E147.
17. Reits, E.A., A.M. Benham, B. Plougastel, J. Neefjes, and J. Trowsdale. 1997. Dynamics of proteasome distribution in living cells. EMBO J. 16:6087-6094.
18. Talcott, B., and M.S. Moore. 1999. Getting across the nuclear pore complex. Trends Cell Biol. 9:312-318.
19. van Ham, S.M., E.P. Tjin, B.F. Lillemeier, U. Gruneberg, K.E. van Meijgaarden, L. Pastoors, D. Verwoerd, A. Tulp, B. Canas, D. Rahman, et al. 1997. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. Curr. Biol. 7:950-957.
20. Varshavsky, A. 2005. Regulated protein degradation. Trends Biochem. Sci. 30:283-286.
21. Wang, H., L. Wang, H. Erdjument-Bromage, M. Vidal, P. Tempst, R.S. Jones, and Y. Zhang. 2004. Role of histone H2A ubiquitination in Polycomb silencing. Nature. 431:873-878.