Response of human DNA polymerase ι to DNA lesions

Nucleic Acids Research

Volumn 29, Issue 4, 2001, Pages 928-935

  Zhang, Yanbin ^a   Yuan, Fenghua ^a   Wu, Xiaohua ^a   Taylor, John Stephen ^b   Wang, Zhigang ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; ADENINE; CYCLOBUTANE; CYTOSINE; DIMER; DNA; DNA POLYMERASE; GENE PRODUCT; GUANINE; THYMINE;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; GENE INSERTION; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL;

ACETOXYACETYLAMINOFLUORENE; BASE SEQUENCE; DNA; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; PYRIMIDINE DIMERS; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC; ULTRAVIOLET RAYS;

EID: 0035865924     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. UmuD′2C is an error-prone DNA polymerase, Escherichia coli pol V
2. The mutagenesis protein UmuC is a DNA polymerase activated by UmuD′, RecA and SSB and is specialized for translesion replication
3. Mutants of yeast defective in mutation induction by ultraviolet light
4. Pathways of ultraviolet mutability in Saccharomyces cerevisiae. III. Genetic analysis and properties of mutants resitant to ultraviolet-induced forward mutation
5. The RAD6 DNA repair pathway in Saccharomyces cerevisiae: What does it do and how does it do it?
6. DNA polymerase ζ and the control of DNA damage induced mutagenesis in eukaryotes
7. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ
8. Deoxycytidyl transferase activity of yeast REV1 protein
9. Thymine-thymine dimer bypass by yeast DNA polymerase ζ
10. The human REV1 gene codes for a DNA template-dependent dCMP transferase
11. Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase η
12. The many faces of DNA polymerases: Strategies for mutagenesis and for mutational avoidance
13. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη
14. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
15. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η
16. Xeroderma pigmentosum
17. Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light
18. Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase η
19. Error-prone lesion bypass by human DNA polymerase η
20. Specificity of DNA lesion bypass by the yeast DNA polymerase η
21. Mechanisms of accurate translesion synthesis by human DNA polymerase η
22. Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η
23. 6-methylguanine by yeast and human DNA polymerase η
24. Preferential incorporation of G opposite template T by the low fidelity human DNA polymerase ι
25. Polι, a remarkably error-prone human DNA polymerase
26. Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions
27. Human DNA polymerase κ synthesizes DNA with extraordinary low fidelity
28. Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro
29. Preparation and characterization of a set of deoxyoligonucleotide 49-mers containing site-specific cis-syn, trans-syn-I, (6-4) and Dewar photoproducts of thymidylyl (3′→5′)-thymidine
30. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
31. N-2-aminofluorence and N-2 acetylaminofluorene adducts: The local sequence context of an adduct and its chemical structure determine its replication properties
32. hRAD30 mutations in the variant form of xeroderma pigmentosum
33. Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase ι
34. Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells
35. Low fidelity DNA synthesis by human DNA polymerase η
36. Fidelity and processivity of DNA synthesis by DNA polymerase κ, the product of the human DINB1 gene
37. Error-prone bypass of certain DNA lesions by the human DNA polymerase κ
38. Pol κ: A DNA polymerase required for sister chromatid cohesion
39. A full-length cDNA of hREV3 is predicted to encode DNA polymerase ζ for damage-induced mutagenesis in humans
40. A human REV7 homolog that interacts with the polymerase ζ catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2