Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase η, DNA polymerase ι causes the very high frequency and unique spectrum of UV-induced mutations

Cancer Research

Volumn 67, Issue 7, 2007, Pages 3018-3026

  Wang, Yun ^a,b   Woodgate, Roger ^c   McManus, Terrence P ^a,b   Mead, Samantha ^c   McCormick, J Justin ^a,b   Maher, Veronica M ^a,b,d  

^a Michigan State University   (United States)

^b NIH ^*  (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; CYCLOBUTANE; DNA DIRECTED DNA POLYMERASE ETA; DNA POLYMERASE; PYRIMIDINE; THYMINE; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE IOTA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MUTAGENICITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ULTRAVIOLET RADIATION; WESTERN BLOTTING; XERODERMA PIGMENTOSUM; AMINO ACID SEQUENCE; BIOSYNTHESIS; CELL LINE; ENZYMOLOGY; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PATHOLOGY; RADIATION EXPOSURE;

AMINO ACID SEQUENCE; CELL LINE; DNA-DIRECTED DNA POLYMERASE; FIBROBLASTS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; TRANSFECTION; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 34248195087     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-3073     Document Type: Article

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