Structure of the Catalytic Core of S. cerevisiae DNA polymerase η: Implications for translesion DNA synthesis

Molecular Cell

Volumn 8, Issue 2, 2001, Pages 417-426

  Trincao, Jose ^a   Johnson, Robert E ^b   Escalante, Carlos R ^a   Prakash, Satya ^b   Prakash, Louise ^b   Aggarwal, Aneel K ^a,c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^{c *}  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; DNA POLYMERASE; ISOENZYME; THYMINE;

ARTICLE; CRYSTAL STRUCTURE; DNA BINDING; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME STRUCTURE; NONHUMAN; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0034847259     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00306-9     Document Type: Article

References (51)

1. Structure of DNA polymerase I Klenow fragment bound to duplex DNA
2. Crystallography & NMR system: A software suite for macromolecular structure determination
3. Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis
4. An attempt to unify the structure of polymerases
5. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution
6. An open and closed case for all polymerases
7. Structure of Taq polymerase with DNA at the polymerase active site
8. Sloppier copier DNA polymerases involved in genome repair
9. 6-methylguanine by yeast and human DNA polymerase η
10. Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η
11. Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1
12. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation
13. Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius
14. Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates
15. hRAD30 mutations in the variant form of xeroderma pigmentosum
16. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη
17. Bridging the gap: A family of novel DNA polymerases that replicate faulty DNA
18. The human DINB1 gene encodes the DNA polymerase Polθ
19. Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions
20. Fidelity of human DNA polymerase η
21. Improved methods for building models in electron density maps and the location of errors in these models
22. 1H NMR study of the exchangeable protons of the duplex d(GCGTTGCG).d(CGCAACGC) containing a thymine photodimer
23. Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
24. Crystal structure of Thermus aquaticus DNA polymerase
25. Contrasting structural impacts induced by cis-syn cyclobutane dimer and (6-4) adduct in DNA duplex decamers: Implication in mutagenesis and repair activity
26. Acidic residues critical for the activity and biological function of yeast DNA polymerase η
27. Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: Structural basis for thermostability
28. Procheck: A program to check the stereochemical quality of protein structures
29. Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation
30. Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation
31. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η
32. Low fidelity DNA synthesis by human DNA polymerase η
33. 2-guanine adducts of 1,3-butadiene metabolites
34. Bacteriophage T7 deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity
35. Error-prone bypass of certain DNA lesions by the human DNA polymerase κ
36. Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
37. Structures of ternary complexes of rat DNA polymerase β, a DNA template-primer, and ddCTP
38. Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli
39. Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli
40. The mutagenesis protein UmuC is a DNA polymerase activated by UmuD′, RecA, and SSB and is specialized for translesion replication
41. Crystal structure of a pol α family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7
42. DNA polymerases: Structural diversity and common mechanisms
43. Thermus aquaticus DNA polymerase I mutants with altered fidelity
44. 2C is an error-prone DNA polymerase, Escherichia coli polV
45. polι, a remarkably error-prone human DNA polymerase
46. The dinB gene encodes a novel E. coli DNA polymerase, DNA Pol IV, involved in mutagenesis
47. Crystal structure of a pol α family replication DNA polymerase from bacteriophage RB69
48. Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase η
49. Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η
50. Crystal structure of an archaebacterial DNA polymerase