Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase

Genomics

Volumn 60, Issue 1, 1999, Pages 20-30

  McDonald, John P ^a   Rapić Otrin, Vesna ^a   Epstein, Jonathan A ^a   Broughton, Bernard C ^b   Wang, Xiangyuan ^c   Lehmann, Alan R ^b   Wolgemuth, Debra J ^c   Woodgate, Roger ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE;

ANIMAL CELL; ARTICLE; CHROMOSOMAL LOCALIZATION; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS INHIBITION; ENZYME ACTIVITY; GENE LOCUS; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA TRANSCRIPTION; SACCHAROMYCES CEREVISIAE; SPERMATOGENESIS; TUMOR SUPPRESSOR GENE; XERODERMA PIGMENTOSUM;

ANIMALIA; ARABIDOPSIS THALIANA; ASPERGILLUS; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; EMERICELLA NIDULANS; EUKARYOTA; MELANOGASTER; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0344631781     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.5906     Document Type: Article

References (59)

1. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
2. Altschul S. F., Boguski M. S., Gish W., Wootton J. C. Issues in searching molecular sequence databases. Nat. Genet. 6:1994;119-129.
3. Aravind L., Walker D. R., Koonin E. V. Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Res. 27:1999;1223-1242.
4. Baarends W. M., Hoogerbrugge J. W., Roest H. P., Ooms M., Vreeburg J., Hoeijmakers J. H., Grootegoed J. A. Histone ubiquitination and chromatin remodeling in mouse spermatogenesis. Dev. Biol. 207:1999;322-333.
5. Banerjee S. K., Christensen R. B., Lawrence C. W., LeClerc J. E. Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine dimer in a single-stranded vector. Proc. Natl. Acad. Sci. USA. 85:1988;8141-8145.
6. Brotcorne-Lannoye A., Maenhaut-Michel G. Role of RecA protein in untargeted UV mutagenesis of bacteriophage λ: Evidence for the requirement for the dinB gene. Proc. Natl. Acad. Sci. USA. 83:1986;3904-3908.
7. Chapman D. L., Wolgemuth D. J. Expression of proliferating cell nuclear antigen in the mouse germ line and surrounding somatic cells suggests both proliferation-dependent and -independent modes of function. Int. J. Dev. Biol. 38:1994;491-497.
8. Cleaver J. E., Carter D. M. Xeroderma pigmentosum variants: Influence of temperature on DNA repair. J. Invest. Dermatol. 60:1973;29-32.
9. Cordeiro-Stone M., Zaritskaya L. S., Price L. K., Kaufmann W. K. Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis. J. Biol. Chem. 272:1997;13945-13954.
10. Cordonnier A. M., Lehmann A. R., Fuchs R. P. P. Impaired translesion synthesis in xeroderma pigmentosum variant extracts. Mol. Cell. Biol. 19:1999;2206-2211.
11. Fearon E. R., Cho K. R., Nigro J. M., Kern S. E., Simons J. W., Ruppert J. M., Hamilton S. R., Preisinger A. C., Thomas G., Kinzler K. W. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science. 247:1990;49-56.
12. Friedberg E. C., Walker G. C., Siede W. DNA Repair and Mutagenesis. 1995;Am. Soc. Microbiol. Washington.
13. Hahn S. A., Schutte M., Hoque A. T., Moskaluk C. A., da Costa L. T., Rozenblum E., Weinstein C. L., Fischer A., Yeo C. J., Hruban R. H., Kern S. E. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 271:1996;350-353.
14. Higgins N. P., Kato K., Strauss B. A model for replication repair in mammalian cells. J. Mol. Biol. 101:1976;417-425.
15. Johnson R. E., Prakash S., Prakash L. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, polη Science. 283:1999a;1001-1004.
16. Johnson R. E., Prakash S., Prakash L. Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function. J. Biol. Chem. 274:1999b;15975-15977.
17. Kim S. R., Maenhaut-Michel G., Yamada M., Yamamoto Y., Matsui K., Sofuni T., Nohmi T., Ohmori H. Multiple pathways for SOS-induced mutagenesis in Escherichia coli: An overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc. Natl. Acad. Sci. USA. 94:1997;13792-13797.
18. Koch W. H., Ennis D. G., Levine A. S., Woodgate R. Escherichia coli umuDC mutants: DNA sequence alterations and UmuD cleavage. Mol. Gen. Genet. 233:1992;443-448.
19. Koffel-Schwartz N., Coin F., Veaute X., Fuchs R. P. P. Cellular strategies for accommodating replication-hindering adducts in DNA: Control by the SOS response in Escherichia coli. Proc. Natl. Acad. Sci. USA. 93:1996;7805-7810.
20. Koken M. H., Hoogerbrugge J. W., Jasper-Dekker I., de Wit J., Willemsen R., Roest H. P., Grootegoed J. A., Hoeijmakers J. H. Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification. Dev. Biol. 173:1996;119-132.
21. Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:1987;8125-8148.
22. Kozak M. Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6. EMBO J. 16:1997;2482-2492.
23. Kulaeva O. I., Koonin E. V., McDonald J. P., Randall S. K., Rabinovich N., Connaughton J. F., Levine A. S., Woodgate R. Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. Mutat. Res. 357:1996;245-253.
24. Lanza G., Matteuzzi M., Gafa R., Orvieto E., Maestri I., Santini A., del Senno L. Chromosome 18q allelic loss and prognosis in stage II and III colon cancer. Int. J. Cancer. 79:1998;390-395.
25. Larimer F. W., Perry J. R., Hardigree A. A. The REV1 gene of Saccharomyces cerevisiae: Isolation, sequence and functional analysis. J. Bacteriol. 171:1989;230-237.
26. Lawrence C. W., Hinkle D. C. DNA polymerase ζ and the control of DNA damage induced mutagenesis in eukaryotes. Lindahl T. Cancer Surveys: Genetic Instability in Cancer. 1996;21-31 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
27. Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO. J. 18:1999a;3491-3501.
28. Masutani C., Kusumoto R., Yamada A., Dohmae N., Yokoi M., Yuasa M., Araki M., Iwai S., Takio K., Hanoaka F. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η Nature. 399:1999b;700-704.
29. McDonald J. P., Levine A. S., Woodgate R. The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism. Genetics. 147:1997;1557-1568.
30. McGregor W. G., Wei D., Maher V. M., McCormick J. J. Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light. Mol. Cell. Biol. 19:1999;147-154.
31. Nellissery M. J., Padalecki S. S., Brkanac Z., Singer F. R., Roodman G. D., Unni K. K., Leach R. J., Hansen M. F. Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone. Am. J. Hum. Genet. 63:1998;817-824.
32. Nelson J. R., Lawrence C. W., Hinkle D. C. Thymine-thymine dimer bypass by yeast DNA polymerase ζ Science. 272:1996a;1646-1649.
33. Nelson J. R., Lawrence C. W., Hinkle D. C. Deoxycytidyl transferase activity of yeast REV1 protein. Nature. 382:1996b;729-731.
34. Oakberg E. F. A description of sperminogenesis in the mouse and its use in analysis of the life cycle of the seminiferous epithelium and germ cell renewal. Am. J. Anat. 99:1956;391-413.
35. Ohmori H., Hatada E., Qiao Y., Tsuji M., Fukuda R. dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues. Mutat. Res. 347:1995;1-7.
36. Papadimitrakopoulou V. A., Oh Y., El-Naggar A., Izzo J., Clayman G., Mao L. Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer. Clin. Cancer Res. 4:1998;539-544.
37. Pearlstein R. P., Benninger M. S., Carey T. E., Zarbo R. J., Torres F. X., Rybicki B. A., Dyke D. L. Loss of 18q predicts poor survival of patients with squamous cell carcinoma of the head and neck. Genes Chromosomes Cancer. 21:1998;333-339.
38. Raha M., Wang G., Seidman M. M., Glazer P. M. Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: High frequency and altered spectrum in a xeroderma pigmentosum variant. Proc. Natl. Acad. Sci. USA. 93:1996;2941-2946.
39. Rhee K., Wolgemuth D. J. Cdk family genes are expressed not only in dividing but also in terminally differentiated mouse germ cells, suggesting their possible function during both cell division and differentiation. Dev. Dyn. 204:1995;406-420.
40. Riggins G. J., Thiagalingam S., Rozenblum E., Weinstein C. L., Kern S. E., Hamilton S. R., Willson J. K., Markowitz S. D., Kinzler K. W., Vogelstein B. Mad-related genes in the human. Nat. Genet. 13:1996;347-349.
41. Roush A. A., Suarez M., Friedberg E. C., Radman M., Siede W. Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability. Mol. Gen. Genet. 257:1998;686-692.
42. Rupp W. D., Howard-Flanders P. Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet radiation. J. Mol. Biol. 31:1968;291-304.
43. Rupp W. D., Wilde C. E., Reno D. L., Howard-Flanders P. Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli. J. Mol. Biol. 61:1971;25-44.
44. Russell L. D., Ettlin R. A., Sinha Hikim A. P., Clegg E. D. Histological and Histopathological Evaluation of the Testis. 1990;Cache River Press, Clearwater.
45. Sega G. A. Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulfonate. Proc. Natl. Acad. Sci. USA. 71:1974;4955-4959.
46. Sega G. A. Unscheduled DNA synthesis (DNA repair) in the germ cells of male mice: Its role in the study of mammalian mutagenesis. Genetics. 92:1979;s49-s58.
47. Sega G. A., Sotomayor R. E., Owens J. G. A study of unscheduled DNA synthesis induced by X-rays in the germ cells of male mice. Mutat. Res. 49:1978;239-257.
48. Smith B. T., Walker G. C. Mutagenesis and more: umuDC and the Escherichia coli SOS response. Genetics. 148:1998;1599-1610.
49. Steinborn G. Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis. I. Isolation of uvm mutants and their phenotypical characterization in DNA repair and mutagenesis. Mol. Gen. Genet. 165:1978;87-93.
50. Svoboda D. L., Vos J. M. Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: Fork uncoupling or gap formation. Proc. Natl. Acad. Sci. USA. 92:1995;11975-11979.
51. Svoboda D. L., Briley L. P., Vos J. M. Defective bypass replication of a leading strand cyclobutane thymine dimer in xeroderma pigmentosum variant cell extracts. Cancer Res. 58:1998;2445-2448.
52. Takei K., Kohno T., Hamada K., Takita J., Noguchi M., Matsuno Y., Hirohashi S., Uezato H., Yokota J. A novel tumor suppressor locus on chromosome 18q involved in the development of human lung cancer. Cancer Res. 58:1998;3700-3705.
53. 2C mutagenic complex and RecA. Proc. Natl. Acad. Sci. USA. 95:1998;9755-9760.
54. 2C is an error-prone DNA polymerase, Escherichia coli DNA pol V. Proc. Natl. Acad. Sci. USA. 96:1999;8919-8924.
55. Thiagalingam S., Lengauer C., Leach F. S., Schutte M., Hahn S. A., Overhauser J., Willson J. K., Markowitz S., Hamilton S. R., Kern S. E., Kinzler K. W., Vogelstein B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat. Genet. 13:1996;343-346.
56. Wagner, J, Gruz, P, Kim, S. R, Yamada, M, Matsui, K, Fuchs, R. P. P, and, Nohmi, T. The dinB gene encodes an novel Escherichia coli DNA polymerase (DNA pol IV) involved in mutagenesis, Mol. Cell, in press.
57. Walker J. E., Saraste M., Runswick M. J., Gay N. J. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases, and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:1982;945-951.
58. Woodgate R., Levine A. S. Damage inducible mutagenesis: Recent insights into the activities of the Umu family of mutagenesis proteins. Lindahl T. Cancer Surveys: Genetic Instability in Cancer. 1996;117-140 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
59. Yokota T., Matsumoto S., Yoshimoto M., Kasumi F., Akiyama F., Sakamoto G., Nakamura Y., Emi M. Mapping of a breast cancer tumor suppressor gene locus to a 4-cM interval on chromosome 18q21. Jpn. J. Cancer Res. 88:1997;959-964.