DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

Nature Immunology

Volumn 2, Issue 6, 2001, Pages 537-541

  Zeng, Xianmin ^a   Winter, David B ^b   Kasmer, Cynthia ^a   Kraemer, Kenneth H ^c   Lehmann, Alan R ^d   Gearhart, Patricia J ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ETA;

ANIMAL; ARTICLE; B LYMPHOCYTE; BASE PAIRING; ENZYMOLOGY; GENETICS; HUMAN; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; XERODERMA PIGMENTOSUM;

ANIMALS; B-LYMPHOCYTES; BASE PAIRING; BASE SEQUENCE; DNA; DNA-DIRECTED DNA POLYMERASE; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; XERODERMA PIGMENTOSUM;

EID: 0035377269     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/88740     Document Type: Article

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