Error-Prone DNA Polymerases: When Making a Mistake is the Only Way to Get Ahead

Annual Review of Genetics

Volumn 37, Issue , 2003, Pages 31-66

  Rattray, Alison J ^a   Strathern, Jeffrey N ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Nonhomologous end joining; Polymerase recruitment; Somatic hypermutation; Translesion polymerase; Untargeted mutagenesis

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BENZO[A]PYRENE; CARCINOGEN; CISPLATIN; CYTOSINE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE ETA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA DIRECTED DNA POLYMERASE KAPPA; DNA DIRECTED DNA POLYMERASE MU; DNA DIRECTED DNA POLYMERASE SIGMA; DNA DIRECTED DNA POLYMERASE XI; DNA HYBRID; DNA POLYMERASE; ESCHERICHIA COLI PROTEIN; HELICASE; IMMUNOGLOBULIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN; PROTEIN XRCC2; PROTEIN XRCC3; RAD51 PROTEIN; RAD51B PROTEIN; RAD55 PROTEIN; RAD57 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

B LYMPHOCYTE; CANCER CELL; CELL LINE; DNA DAMAGE; DNA REPLICATION; DNA SEQUENCE; DNA STRAND BREAKAGE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME REGULATION; ESCHERICHIA COLI; EUKARYOTE; GENE MUTATION; GENOME; GENOTOXICITY; HEAT STRESS; HUMAN; HYDROXYLATION; MUTAGENESIS; MUTATION RATE; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; SKIN CANCER; SOMATIC CELL; ULTRAVIOLET RADIATION; YEAST;

DNA; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; EUKARYOTIC CELLS; MUTATION;

ESCHERICHIA COLI; EUKARYOTA;

EID: 0347416710     PISSN: 00664197     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genet.37.042203.132748     Document Type: Review

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