An Incoming Nucleotide Imposes an anti to syn Conformational Change on the Templating Purine in the Human DNA Polymerase-ι Active Site

Structure

Volumn 14, Issue 4, 2006, Pages 749-755

  Nair, Deepak T ^a   Johnson, Robert E ^b   Prakash, Louise ^b   Prakash, Satya ^b   Aggarwal, Aneel K ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

DNA

Indexed keywords

DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE IOTA; DNA POLYMERASE; NUCLEOTIDE; PARATHION; PURINE; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; DNA REPLICATION; ENZYME ACTIVE SITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION;

BASE PAIRING; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GLUTATHIONE TRANSFERASE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PURINES; RECOMBINANT FUSION PROTEINS;

EID: 33646492746     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2006.01.010     Document Type: Article

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