Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase ι

EMBO Journal

Volumn 19, Issue 19, 2000, Pages 5259-5266

  Tissier, Agnès ^a   Frank, Ekaterina G ^a   Mcdonald, John P ^a   Iwai, Shigenori ^b   Hanaoka, Fumio ^c,d   Woodgate, Roger ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b BIOMOL ENG RESEARCH INSTITUTE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

DNA polymerase ; DNA polymerase ; Rad30; Rad30B; Xeroderma pigmentosum variant

Indexed keywords

DNA POLYMERASE;

ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA TEMPLATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION; XERODERMA PIGMENTOSUM;

EID: 0034596992     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.19.5259     Document Type: Article

References (34)

1. DNA polymerase insertion fidelity. Gel assay for site-specific kinetics
2. Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis
3. Impaired translesion synthesis in xeroderma pigmentosum variant extracts
4. Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading and lesion bypass efficiencies
5. Bypass of a site-specific cis-syn thymine dimer in an SV40 vector during in vitro replication by HeLa and XPV cell-free extracts
6. Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily
7. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ
8. The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light
9. Eukaryotic DNA polymerases, a growing family
10. hRAD30 mutations in the variant form of xeroderma pigmentosum
11. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, polη
12. Fidelity of human DNA polymerase η
13. Roles of DNA polymerase ζ and Rev1 protein in eukaryotic mutagenesis and translesion replication
14. A full-length cDNA of hREV3 is predicted to encode DNA polymerase ζ for damage-induced mutagenesis in humans
15. The human REV1 gene codes for a DNA template-dependent dCMP transferase
16. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
17. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η
18. Mechanisms of accurate translesion synthesis by human DNA polymerase η
19. Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase η
20. Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light
21. Alternative splicing, genomic structure and fine chromosome localization of REV3L
22. A human REV7 homolog that interacts with the polymerase ζ catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2
23. Thymine-thymine dimer bypass by yeast DNA polymerase ζ
24. Deoxycytidyl transferase activity of yeast REV1 protein
25. Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein DinB
26. Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: High frequency and altered spectrum in a xeroderma pigmentosum variant
27. polι, A remarkably error-prone human DNA polymerase
28. Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase η
29. Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts
30. Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η
31. A plethora of lesion-replicating DNA polymerases
32. Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase ζ
33. Specificity of DNA lesion bypass by the yeast DNA polymerase η