Lesion bypass of N 2-ethylguanine by human DNA polymerase i

Journal of Biological Chemistry

Volumn 284, Issue 3, 2009, Pages 1732-1740

  Pence, Matthew G ^a   Blans, Patrick ^b   Zink, Charles N ^b   Holliss, Thomas ^a   Fishbein, James C ^b   Perrino, Fred W ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^b UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING METALS; ACTIVE SITES; BASE PAIRS; CATALYZED REACTIONS; DNA ADDUCT; DNA POLYMERASE; KINETIC ANALYSIS; KINETIC DATUM; LESION BYPASS; MINOR GROOVES; STEADY STATE; STERIC OVERLAPS;

DNA; GENES; MANGANESE; MANGANESE COMPOUNDS; NUCLEOTIDES; ORGANIC ACIDS; POLYMERS;

NUCLEIC ACIDS;

DEOXYCYTIDINE PHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DNA POLYMERASE; DNA POLYMERASE IOTA; GUANINE DERIVATIVE; MAGNESIUM ION; MANGANESE; N 2 ETHYLGAUNINE; NUCLEOTIDE; UNCLASSIFIED DRUG; CYTOSINE; DNA DIRECTED DNA POLYMERASE; DRUG DERIVATIVE; GUANINE; MAGNESIUM;

ARTICLE; BASE PAIRING; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN DOMAIN; STEADY STATE; STRUCTURE ANALYSIS; CHEMISTRY; DNA ADDUCT; DNA REPLICATION; HUMAN; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

CATALYSIS; CATALYTIC DOMAIN; CYTOSINE; DNA ADDUCTS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; KINETICS; MAGNESIUM; MANGANESE; NUCLEOTIDES; PROTEIN STRUCTURE, TERTIARY;

EID: 59149105305     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807296200     Document Type: Article

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