Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase κ

Journal of Biological Chemistry

Volumn 281, Issue 30, 2006, Pages 21062-21072

  Choi, Jeong Yun ^a,b   Angel, Karen C ^a   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Ewha Womans University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; CHEMICAL MODIFICATION; DNA; ENZYMES; MOLECULAR BIOLOGY; NITROGEN COMPOUNDS; SOLVENTS; SYNTHESIS (CHEMICAL);

HUMAN DNA POLYMERASE; HUMAN POLS; TRANSLESION POLYMERASES; TRANSLESION SYNTHESIS;

BIODIVERSITY;

ALPHA THIO DEOXYCYTIDINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DNA POLYMERASE; DNA POLYMERASE KAPPA; GUANINE DERIVATIVE; METHYL(6 BENZO[A]PYRENYL); METHYLENE(6 BENZO[A]PYRENYL); N2 GUANINE DERIVATIVE; OLIGONUCLEOTIDE; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DNA ADDUCT; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; HUMAN; PRIORITY JOURNAL; STEADY STATE;

BACULOVIRIDAE; BINDING SITES; CATALYSIS; DEOXYCYTOSINE NUCLEOTIDES; DNA ADDUCTS; DNA DAMAGE; DNA, COMPLEMENTARY; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; KINETICS; MODELS, CHEMICAL; OLIGONUCLEOTIDES; TIME FACTORS;

EID: 33746330759     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602246200     Document Type: Article

References (71)

1. Friedberg, E. C., Walker, G. C., Siede, W., Wood, R. D., Schultz, R. A., and Ellenberger, T. (2006) DNA Repair and Mutagenesis, 2nd Ed., American Society of Microbiology Press, Washington, D. C.
2. Ramos, K. S., and Moorthy, B. (2005) Drug Metab. Rev. 37, 595-610
3. Goodman, M. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10493-10495
4. Guengerich, F. P. (2006) Chem. Rev. 106, 420-452
5. Goodman, M. F. (2002) Annu. Rev. Biochem. 71, 17-50
6. Gerlach, V. L., Aravind, L., Gotway, G., Schultz, R. A., Koonin, E. V., and Friedberg, E. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11922-11927
7. Ogi, T., Kato, T., Jr., Kato, T., and Ohmori, H. (1999) Genes Cells 4, 607-618
8. Uljon, S. N., Johnson, R. E., Edwards, T. A., Prakash, S., Prakash, L., and Aggarwal, A. K. (2004) Structure (Cambridge) 12, 1395-1404
9. Zhang, Y., Yuan, F., Wu, X., Wang, M., Rechkoblit, O., Taylor, J. S., Geacintov, N. E., and Wang, Z. (2000) Nucleic Acids Res. 28, 4138-4146
10. Gerlach, V. L., Feaver, W. J., Fischhaber, P. L., and Friedberg, E. C. (2001) J. Biol. Chem. 276, 92-98
11. Rechkoblit, O., Zhang, Y., Guo, D., Wang, Z., Amin, S., Krzeminsky, J., Louneva, N., and Geacintov, N. E. (2002) J. Biol. Chem. 277, 30488-30494
12. Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., and Wang, Z. (2002) DNA Repair (Amst.) 1, 559-569
13. Suzuki, N., Ohashi, E., Kolbanovskiy, A., Geacintov, N. E., Grollman, A. P., Ohmori, H., and Shibutani, S. (2002) Biochemistry 41, 6100-6106
14. Huang, X., Kolbanovskiy, A., Wu, X., Zhang, Y., Wang, Z., Zhuang, P., Amin, S., and Geacintov, N. E. (2003) Biochemistry 42, 2456-2466
15. Yasui, M., Suzuki, N., Miller, H., Matsuda, T., Matsui, S., and Shibutani, S. (2004) J. Mol. Biol. 344, 665-674
16. Suzuki, N., Yasui, M., Geacintov, N. E., Shafirovich, V., and Shibutani, S. (2005) Biochemistry 44, 9238-9245
17. Suzuki, N., Itoh, S., Poon, K., Masutani, C., Hanaoka, F., Ohmori, H., Yoshizawa, I., and Shibutani, S. (2004) Biochemistry 43, 6304-6311
18. Ohashi, E., Bebenek, K., Matsuda, T., Feaver, W. J., Gerlach, V. L., Friedberg, E. C., Ohmori, H., and Kunkel, T. A. (2000) J. Biol. Chem. 275, 39678-39684
19. Levine, R. L., Miller, H., Grollman, A., Ohashi, E., Ohmori, H., Masutani, C., Hanaoka, F., and Moriya, M. (2001) J. Biol. Chem. 276, 18717-18721
20. Haracska, L., Prakash, L., and Prakash, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16000-16005
21. Singer, B., Medina, M., Zhang, Y., Wang, Z., Guliaev, A. B., and Hang, B. (2002) Biochemistry 41, 1778-1785
22. O-Wang, J., Kawamura, K., Tada, Y., Ohmori, H., Kimura, H., Sakiyama, S., and Tagawa, M. (2001) Cancer Res. 61, 5366-5369
23. Schenten, D., Gerlach, V. L., Guo, C., Velasco-Miguel, S., Hladik, C. L., White, C. L., Friedberg, E. C., Rajewsky, K., and Esposito, G. (2002) Eur. J. Immunol. 32, 3152-3160
24. Bavoux, C., Hoffmann, J. S., and Cazaux, C. (2005) Biochimie (Paris) 87, 637-646
25. Washington, M. T., Johnson, R. E., Prakash, L., and Prakash, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1910-1914
26. Prakash, S., Johnson, R. E., and Prakash, L. (2005) Annu. Rev. Biochem. 74, 317-353
27. Johnson, K. A. (1993) Annu. Rev. Biochem. 62, 685-713
28. Choi, Y.-J., and Guengerich, F. P. (2004) J. Biol. Chem. 279, 19217-19229
29. Choi, J.-Y., and Guengerich, F. P. (2005) J. Mol. Biol. 352, 72-90
30. Choi, J.-Y., and Guengerich, F. P. (2006) J. Biol. Chem. 281, 12315-12324
31. Borer, P. N. (1975) in Handbook of Biochemistry and Molecular Biology (Fasman, G. D., ed) pp. 589-590, 3rd Ed., CRC Press, Cleveland, OH
32. Wray, W., Boulikas, T., Wray, V. P., and Hancock, R. (1981) Anal. Biochem. 118, 197-203
33. Fien, K., and Stillman, B. (1992) Mol. Cell Biol. 12, 155-163
34. Einolf, H. J., and Guengerich, F. P. (2000) J. Biol. Chem. 275, 16316-16322
35. Goodman, M. F., Creighton, S., Bloom, L. B., and Petruska, J. (1993) Crit. Rev. Biochem. Mol. Biol. 28, 83-126
36. Patel, S. S., Wong, I., and Johnson, K. A. (1991) Biochemistry 30, 511-525
37. Johnson, K. A. (1995) Methods Enzymol. 249, 38-61
38. Haracska, L., Unk, I., Johnson, R. E., Phillips, B. B., Hurwitz, J., Prakash, L., and Prakash, S. (2002) Mol. Cell Biol. 22, 784-791
39. Lowe, L. G., and Guengerich, F. P. (1996) Biochemistry 35, 9840-9849
40. Furge, L. L., and Guengerich, F. P. (1997) Biochemistry 36, 6475-6487
41. Woodside, A. M., and Guengerich, F. P. (2002) Biochemistry 41, 1027-1038
42. Zang, H., Harris, T. M., and Guengerich, F. P. (2005) J. Biol. Chem. 280, 1165-1178
43. Zang, H., Harris, T. M., and Guengerich, F. P. (2005) Chem. Res. Toxicol. 18, 389-400
44. Zang, H., Goodenough, A. K., Choi, J.-Y., Irminia, A., Loukachevitch, L. V., Kozekov, I. D., Angel, K. C., Rizzo, C. J., Egli, M., and Guengerich, F. P. (2005) J. Biol. Chem. 280, 29750-29764
45. Zang, H., Irminia, A., Choi, J.-Y., Angel, K. C., Loukachevitch, L. V., Egli, M., and Guengerich, F. P. (2006) J. Biol. Chem. 281, 2358-2372
46. Washington, M. T., Minko, I. G., Johnson, R. E., Wolfle, W. T., Harris, T. M., Lloyd, R. S., Prakash, S., and Prakash, L. (2004) Mol. Cell Biol. 24, 5687-5693
47. Wolfle, W. T., Johnson, R. E., Minko, I. G., Lloyd, R. S., Prakash, S., and Prakash, L. (2006) Mol. Cell Biol. 26, 381-386
48. Furge, L. L., and Guengerich, F. P. (1999) Biochemistry 38, 4818-4825
49. Suo, Z., and Johnson, K. A. (1998) J. Biol. Chem. 273, 27259-27267
50. Johnson, K. A. (2003) in Kinetic Analysis of Macromolecules: A Practical Approach (Johnson, K. A., ed) pp. 1-18, Oxford University Press, Oxford, UK
51. Mizrahi, V., Henrie, R. N., Marlier, J. F., Johnson, K. A., and Benkovic, S. J. (1985) Biochemistry 24, 4010-4018
52. Kuchta, R. D., Mizrahi, V., Benkovic, P. A., Johnson, K. A., and Benkovic, S. J. (1987) Biochemistry 26, 8410-8417
53. Herschlag, D., Piccirilli, J. A., and Cech, T. R. (1991) Biochemistry 30, 4844-4854
54. Fiala, K. A., and Suo, Z. (2004) Biochemistry 43, 2106-2115
55. Nair, D. T., Johnson, R. E., Prakash, S., Prakash, L., and Aggarwal, A. K. (2004) Nature 430, 377-380
56. Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., and Aggarwal, A. K. (2005) Structure (Cambridge) 13, 1569-1577
57. Connolly, M. L. (1993) J. Mol. Graph. 11, 139-141
58. Wolfle, W. T., Washington, M. T., Kool, E. T., Spratt, T. E., Helquist, S. A., Prakash, L., and Prakash, S. (2005) Mol. Cell Biol. 25, 7137-7143
59. Jarosz, D. F., Godoy, V. G., Delaney, J. C., Essigmann, J. M., and Walker, G. C. (2006) Nature 439, 225-228
60. Joyce, C. M., and Benkovic, S. J. (2004) Biochemistry 43, 14317-14324
61. Showalter, A. K., and Tsai, M. D. (2002) Biochemistry 41, 10571-10576
62. Fiala, K. A., and Suo, Z. (2004) Biochemistry 43, 2116-2125
63. Polesky, A. H., Dahlberg, M. E., Benkovic, S. J., Grindley, N. D. F., and Joyce, C. M. (1992) J. Biol. Chem. 267, 8417-8428
64. Zhong, X., Patel, S. S., Werneburg, B. G., and Tsai, M. D. (1997) Biochemistry 36, 11891-11900
65. Eger, B. T., and Benkovic, S. J. (1992) Biochemistry 31, 9227-9236
66. Furge, L. L., and Guengerich, F. P. (1998) Biochemistry 37, 3567-3574
67. Hübscher, U., Maga, G., and Spadari, S. (2002) Annu. Rev. Biochem. 71, 133-163
68. Avkin, S., Goldsmith, M., Velasco-Miguel, S., Geacintov, N., Friedberg, E. C., and Livneh, Z. (2004) J. Biol. Chem. 279, 53298-53305
69. Ogi, T., Kannouche, P., and Lehmann, A. R. (2005) J. Cell Sci. 118, 129-136
70. Haracska, L., Torres-Ramos, C. A., Johnson, R. E., Prakash, S., and Prakash, L. (2004) Mol. Cell Biol. 24, 4267-4274
71. Watanabe, K., Tateishi, S., Kawasuji, M., Tsurimoto, T., Inoue, H., and Yamaizumi, M. (2004) EMBO J. 23, 3886-3896