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Volumn 3, Issue 12, 2004, Pages 1617-1638

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6)

Author keywords

Database; DNA; Mouse mutant strain

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; ATM PROTEIN; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; DNA METHYLTRANSFERASE; ENDONUCLEASE; EXONUCLEASE; GENE PRODUCT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HISTONE; MISMATCH REPAIR PROTEIN PMS2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6; PROTEIN P16; PROTEIN P21; RAD50 PROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; RECA PROTEIN; URACIL DNA GLYCOSYLTRANSFERASE;

EID: 5044247389     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2004.06.016     Document Type: Article
Times cited : (25)

References (160)
  • 1
    • 0034738030 scopus 로고    scopus 로고
    • Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 4
    • E.C. Friedberg, and L.B. Meira Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 4 Mutat. Res. 459 2000 243 274
    • (2000) Mutat. Res. , vol.459 , pp. 243-274
    • Friedberg, E.C.1    Meira, L.B.2
  • 5
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • H. Gu, J.D. Marth, P.C. Orban, H. Mossmann, and K. Rajewsky Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting Science 265 1994 103 106
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 6
    • 5044241671 scopus 로고    scopus 로고
    • Personal communication.
    • R. Sobol, Personal communication.
    • Sobol, R.1
  • 7
    • 0029829265 scopus 로고    scopus 로고
    • The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice
    • S. Xanthoudakis, R.J. Smeyne, J.D. Wallace, and T. Curran The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice Proc. Natl. Acad. Sci. U.S.A. 93 1996 8919 8923
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 8919-8923
    • Xanthoudakis, S.1    Smeyne, R.J.2    Wallace, J.D.3    Curran, T.4
  • 10
    • 0030016920 scopus 로고    scopus 로고
    • DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability
    • D. Bentley, J. Selfridge, J.K. Millar, K. Samuel, N. Hole, J.D. Ansell, and D.W. Melton DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability Nat. Genet. 13 1996 489 491
    • (1996) Nat. Genet. , vol.13 , pp. 489-491
    • Bentley, D.1    Selfridge, J.2    Millar, J.K.3    Samuel, K.4    Hole, N.5    Ansell, J.D.6    Melton, D.W.7
  • 14
    • 0141594940 scopus 로고    scopus 로고
    • Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases
    • B. Karahalil, N.C. de Souza-Pinto, J.L. Parsons, R.H. Elder, and V.A. Bohr Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases J. Biol. Chem. 278 2003 33701 33707
    • (2003) J. Biol. Chem. , vol.278 , pp. 33701-33707
    • Karahalil, B.1    De Souza-Pinto, N.C.2    Parsons, J.L.3    Elder, R.H.4    Bohr, V.A.5
  • 17
    • 0030707950 scopus 로고    scopus 로고
    • Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine
    • B. Hang, B. Singer, G.P. Margison, and R.H. Elder Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine Proc. Natl. Acad. Sci. U.S.A. 94 1997 12869 12874
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 12869-12874
    • Hang, B.1    Singer, B.2    Margison, G.P.3    Elder, R.H.4
  • 19
    • 5044243450 scopus 로고    scopus 로고
    • Unpublished observations.
    • J.H.M.H. Yang, Unpublished observations.
    • Yang, J.H.M.H.1
  • 20
    • 0042091947 scopus 로고    scopus 로고
    • Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
    • E. Larsen, C. Gran, B.E. Saether, E. Seeberg, and A. Klungland Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage Mol. Cell. Biol. 23 2003 5346 5353
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5346-5353
    • Larsen, E.1    Gran, C.2    Saether, B.E.3    Seeberg, E.4    Klungland, A.5
  • 21
    • 0042470700 scopus 로고    scopus 로고
    • Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability
    • C. Spiro, and C.T. McMurray Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability Mol. Cell. Biol. 23 2003 6063 6074
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6063-6074
    • Spiro, C.1    McMurray, C.T.2
  • 22
    • 0027378895 scopus 로고
    • Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning
    • J. McWhir, J. Selfridge, D.J. Harrison, S. Squires, and D.W. Melton Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning Nat. Genet. 5 1993 217 224
    • (1993) Nat. Genet. , vol.5 , pp. 217-224
    • McWhir, J.1    Selfridge, J.2    Harrison, D.J.3    Squires, S.4    Melton, D.W.5
  • 25
    • 0029147115 scopus 로고
    • High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group a gene
    • H. Nakane, S. Takeuchi, S. Yuba, M. Saijo, Y. Nakatsu, H. Murai, Y. Nakatsuru, T. Ishikawa, S. Hirota, and Y. Kitamura High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene Nature 377 1995 165 168
    • (1995) Nature , vol.377 , pp. 165-168
    • Nakane, H.1    Takeuchi, S.2    Yuba, S.3    Saijo, M.4    Nakatsu, Y.5    Murai, H.6    Nakatsuru, Y.7    Ishikawa, T.8    Hirota, S.9    Kitamura, Y.10
  • 27
    • 0028978672 scopus 로고
    • High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC
    • A.T. Sands, A. Abuin, A. Sanchez, C.J. Conti, and A. Bradley High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC Nature 377 1995 162 165
    • (1995) Nature , vol.377 , pp. 162-165
    • Sands, A.T.1    Abuin, A.2    Sanchez, A.3    Conti, C.J.4    Bradley, A.5
  • 31
    • 0142213242 scopus 로고    scopus 로고
    • P53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group a gene
    • F. Ide, M. Kitada, H. Sakashita, K. Kusama, K. Tanaka, and T. Ishikawa p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene Am. J. Pathol. 163 2003 1729 1733
    • (2003) Am. J. Pathol. , vol.163 , pp. 1729-1733
    • Ide, F.1    Kitada, M.2    Sakashita, H.3    Kusama, K.4    Tanaka, K.5    Ishikawa, T.6
  • 32
    • 0030480945 scopus 로고    scopus 로고
    • Synergistic interactions between XPC and p53 mutations in double-mutant mice: Neural tube abnormalities and accelerated UV radiation-induced skin cancer
    • D.L. Cheo, L.B. Meira, R.E. Hammer, D.K. Burns, A.T. Doughty, and E.C. Friedberg Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer Curr. Biol. 6 1996 1691 1694
    • (1996) Curr. Biol. , vol.6 , pp. 1691-1694
    • Cheo, D.L.1    Meira, L.B.2    Hammer, R.E.3    Burns, D.K.4    Doughty, A.T.5    Friedberg, E.C.6
  • 34
    • 0034654169 scopus 로고    scopus 로고
    • Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: Genotype-specific effects on cancer predisposition and pathology of tumors
    • D.L. Cheo, L.B. Meira, D.K. Burns, A.M. Reis, T. Issac, and E.C. Friedberg Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors Cancer Res. 60 2000 1580 1584
    • (2000) Cancer Res. , vol.60 , pp. 1580-1584
    • Cheo, D.L.1    Meira, L.B.2    Burns, D.K.3    Reis, A.M.4    Issac, T.5    Friedberg, E.C.6
  • 35
    • 0036837527 scopus 로고    scopus 로고
    • Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer
    • L.B. Meira, D.L. Cheo, A.M. Reis, N. Claij, D.K. Burns, H. te Riele, and E.C. Friedberg Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer DNA Repair (Amst) 1 2002 929 934
    • (2002) DNA Repair (Amst) , vol.1 , pp. 929-934
    • Meira, L.B.1    Cheo, D.L.2    Reis, A.M.3    Claij, N.4    Burns, D.K.5    Te Riele, H.6    Friedberg, E.C.7
  • 37
    • 0031964151 scopus 로고    scopus 로고
    • Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality
    • J. de Boer, I. Donker, J. de Wit, J.H. Hoeijmakers, and G. Weeda Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality Cancer Res. 58 1998 89 94
    • (1998) Cancer Res. , vol.58 , pp. 89-94
    • De Boer, J.1    Donker, I.2    De Wit, J.3    Hoeijmakers, J.H.4    Weeda, G.5
  • 39
    • 5044244406 scopus 로고    scopus 로고
    • Personal communication.
    • P. Raychaudhuri, Personal communication.
    • Raychaudhuri, P.1
  • 40
    • 1242296809 scopus 로고    scopus 로고
    • DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen
    • T. Itoh, D. Cado, R. Kamide, and S. Linn DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen Proc. Natl. Acad. Sci. U.S.A. 101 2004 2052 2057
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 2052-2057
    • Itoh, T.1    Cado, D.2    Kamide, R.3    Linn, S.4
  • 41
    • 1542309071 scopus 로고    scopus 로고
    • Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF
    • M. Tian, R. Shinkura, N. Shinkura, and F.W. Alt Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF Mol. Cell. Biol. 24 2004 1200 1205
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1200-1205
    • Tian, M.1    Shinkura, R.2    Shinkura, N.3    Alt, F.W.4
  • 42
    • 0032980573 scopus 로고    scopus 로고
    • Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene
    • Y.N. Harada, N. Shiomi, M. Koike, M. Ikawa, M. Okabe, S. Hirota, Y. Kitamura, M. Kitagawa, T. Matsunaga, O. Nikaido, and T. Shiomi Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene Mol. Cell. Biol. 19 1999 2366 2372
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2366-2372
    • Harada, Y.N.1    Shiomi, N.2    Koike, M.3    Ikawa, M.4    Okabe, M.5    Hirota, S.6    Kitamura, Y.7    Kitagawa, M.8    Matsunaga, T.9    Nikaido, O.10    Shiomi, T.11
  • 43
    • 5044241279 scopus 로고    scopus 로고
    • Personal communication.
    • T. Shiomi, Personal communication.
    • Shiomi, T.1
  • 44
    • 1542284083 scopus 로고    scopus 로고
    • Deficiency in the nuclease activity of xeroderma pigmentosum G in mice leads to hypersensitivity to UV irradiation
    • M. Tian, D.A. Jones, M. Smith, R. Shinkura, and F.W. Alt Deficiency in the nuclease activity of xeroderma pigmentosum G in mice leads to hypersensitivity to UV irradiation Mol. Cell. Biol. 24 2004 2237 2242
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 2237-2242
    • Tian, M.1    Jones, D.A.2    Smith, M.3    Shinkura, R.4    Alt, F.W.5
  • 45
    • 1942518432 scopus 로고    scopus 로고
    • Identification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in method
    • N. Shiomi, S. Kito, M. Oyama, T. Matsunaga, Y.N. Harada, M. Ikawa, M. Okabe, and T. Shiomi Identification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in method Mol. Cell. Biol. 24 2004 3712 3719
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3712-3719
    • Shiomi, N.1    Kito, S.2    Oyama, M.3    Matsunaga, T.4    Harada, Y.N.5    Ikawa, M.6    Okabe, M.7    Shiomi, T.8
  • 54
    • 0042790463 scopus 로고    scopus 로고
    • MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine
    • O.J. Sansom, J. Zabkiewicz, S.M. Bishop, J. Guy, A. Bird, and A.R. Clarke MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine Oncogene 22 2003 7130 7136
    • (2003) Oncogene , vol.22 , pp. 7130-7136
    • Sansom, O.J.1    Zabkiewicz, J.2    Bishop, S.M.3    Guy, J.4    Bird, A.5    Clarke, A.R.6
  • 58
    • 0029101616 scopus 로고
    • Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
    • N. de Wind, M. Dekker, A. Berns, M. Radman, and H. te Riele Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer Cell 82 1995 321 330
    • (1995) Cell , vol.82 , pp. 321-330
    • De Wind, N.1    Dekker, M.2    Berns, A.3    Radman, M.4    Te Riele, H.5
  • 64
    • 0031600949 scopus 로고    scopus 로고
    • No female embryonic lethality in mice nullizygous for Msh2 and p53
    • N.J. Toft, M.J. Arends, A.H. Wyllie, and A.R. Clarke No female embryonic lethality in mice nullizygous for Msh2 and p53 Nat. Genet. 18 1998 17
    • (1998) Nat. Genet. , vol.18 , pp. 17
    • Toft, N.J.1    Arends, M.J.2    Wyllie, A.H.3    Clarke, A.R.4
  • 67
    • 0035503172 scopus 로고    scopus 로고
    • The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
    • M. Kuraguchi, K. Yang, E. Wong, E. Avdievich, K. Fan, R.D. Kolodner, M. Lipkin, A.M. Brown, R. Kucherlapati, and W. Edelmann The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis Cancer Res. 61 2001 7934 7942
    • (2001) Cancer Res. , vol.61 , pp. 7934-7942
    • Kuraguchi, M.1    Yang, K.2    Wong, E.3    Avdievich, E.4    Fan, K.5    Kolodner, R.D.6    Lipkin, M.7    Brown, A.M.8    Kucherlapati, R.9    Edelmann, W.10
  • 69
  • 83
    • 0034672057 scopus 로고    scopus 로고
    • Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice
    • B. Deans, C.S. Griffin, M. Maconochie, and J. Thacker Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice EMBO J. 19 2000 6675 6685
    • (2000) EMBO J. , vol.19 , pp. 6675-6685
    • Deans, B.1    Griffin, C.S.2    MacOnochie, M.3    Thacker, J.4
  • 85
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • C. Zhu, M.A. Bogue, D.S. Lim, P. Hasty, and D.B. Roth Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates Cell 86 1996 379 389
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.S.3    Hasty, P.4    Roth, D.B.5
  • 91
    • 0032585526 scopus 로고    scopus 로고
    • Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
    • D.E. Barnes, G. Stamp, I. Rosewell, A. Denzel, and T. Lindahl Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice Curr. Biol. 8 1998 1395 1398
    • (1998) Curr. Biol. , vol.8 , pp. 1395-1398
    • Barnes, D.E.1    Stamp, G.2    Rosewell, I.3    Denzel, A.4    Lindahl, T.5
  • 93
    • 0032167446 scopus 로고    scopus 로고
    • A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination
    • Y. Gao, J. Chaudhuri, C. Zhu, L. Davidson, D.T. Weaver, and F.W. Alt A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination Immunity 9 1998 367 376
    • (1998) Immunity , vol.9 , pp. 367-376
    • Gao, Y.1    Chaudhuri, J.2    Zhu, C.3    Davidson, L.4    Weaver, D.T.5    Alt, F.W.6
  • 96
    • 0028922462 scopus 로고
    • Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease
    • Z.Q. Wang, B. Auer, L. Stingl, H. Berghammer, D. Haidacher, M. Schweiger, and E.F. Wagner Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease Genes Dev. 9 1995 509 520
    • (1995) Genes Dev. , vol.9 , pp. 509-520
    • Wang, Z.Q.1    Auer, B.2    Stingl, L.3    Berghammer, H.4    Haidacher, D.5    Schweiger, M.6    Wagner, E.F.7
  • 100
    • 0030679762 scopus 로고    scopus 로고
    • Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis
    • C. Morrison, G.C. Smith, L. Stingl, S.P. Jackson, E.F. Wagner, and Z.Q. Wang Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis Nat. Genet. 17 1997 479 482
    • (1997) Nat. Genet. , vol.17 , pp. 479-482
    • Morrison, C.1    Smith, G.C.2    Stingl, L.3    Jackson, S.P.4    Wagner, E.F.5    Wang, Z.Q.6
  • 101
    • 0037219382 scopus 로고    scopus 로고
    • Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice
    • W.M. Tong, H. Ohgaki, H. Huang, C. Granier, P. Kleihues, and Z.Q. Wang Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice Am. J. Pathol. 162 2003 343 352
    • (2003) Am. J. Pathol. , vol.162 , pp. 343-352
    • Tong, W.M.1    Ohgaki, H.2    Huang, H.3    Granier, C.4    Kleihues, P.5    Wang, Z.Q.6
  • 105
    • 0033594904 scopus 로고    scopus 로고
    • Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
    • G. Luo, M.S. Yao, C.F. Bender, M. Mills, A.R. Bladl, A. Bradley, and J.H. Petrini Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation Proc. Natl. Acad. Sci. U.S.A. 96 1999 7376 7381
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 7376-7381
    • Luo, G.1    Yao, M.S.2    Bender, C.F.3    Mills, M.4    Bladl, A.R.5    Bradley, A.6    Petrini, J.H.7
  • 107
    • 0033501050 scopus 로고    scopus 로고
    • Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background
    • Z. Shu, S. Smith, L. Wang, M.C. Rice, and E.B. Kmiec Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background Mol. Cell. Biol. 19 1999 8686 8693
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8686-8693
    • Shu, Z.1    Smith, S.2    Wang, L.3    Rice, M.C.4    Kmiec, E.B.5
  • 108
    • 0034074273 scopus 로고    scopus 로고
    • Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3
    • D.L. Pittman, and J.C. Schimenti Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3 Genesis 26 2000 167 173
    • (2000) Genesis , vol.26 , pp. 167-173
    • Pittman, D.L.1    Schimenti, J.C.2
  • 109
    • 0029909565 scopus 로고    scopus 로고
    • A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
    • D.S. Lim, and P. Hasty A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53 Mol. Cell. Biol. 16 1996 7133 7143
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 7133-7143
    • Lim, D.S.1    Hasty, P.2
  • 112
    • 0035936554 scopus 로고    scopus 로고
    • Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice
    • J. Zhu, S. Petersen, L. Tessarollo, and A. Nussenzweig Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice Curr. Biol. 11 2001 105 109
    • (2001) Curr. Biol. , vol.11 , pp. 105-109
    • Zhu, J.1    Petersen, S.2    Tessarollo, L.3    Nussenzweig, A.4
  • 113
    • 0037086702 scopus 로고    scopus 로고
    • Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
    • J. Kang, R.T. Bronson, and Y. Xu Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair EMBO J. 21 2002 1447 1455
    • (2002) EMBO J. , vol.21 , pp. 1447-1455
    • Kang, J.1    Bronson, R.T.2    Xu, Y.3
  • 114
  • 115
    • 0030051903 scopus 로고    scopus 로고
    • Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
    • L.C. Gowen, B.L. Johnson, A.M. Latour, K.K. Sulik, and B.H. Koller Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities Nat. Genet. 12 1996 191 194
    • (1996) Nat. Genet. , vol.12 , pp. 191-194
    • Gowen, L.C.1    Johnson, B.L.2    Latour, A.M.3    Sulik, K.K.4    Koller, B.H.5
  • 116
    • 0032542216 scopus 로고    scopus 로고
    • A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability
    • S.X. Shen, Z. Weaver, X. Xu, C. Li, M. Weinstein, L. Chen, X.Y. Guan, T. Ried, and C.X. Deng A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability Oncogene 17 1998 3115 3124
    • (1998) Oncogene , vol.17 , pp. 3115-3124
    • Shen, S.X.1    Weaver, Z.2    Xu, X.3    Li, C.4    Weinstein, M.5    Chen, L.6    Guan, X.Y.7    Ried, T.8    Deng, C.X.9
  • 117
    • 0029784528 scopus 로고    scopus 로고
    • Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development
    • C.Y. Liu, A. Flesken-Nikitin, S. Li, Y. Zeng, and W.H. Lee Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development Genes Dev. 10 1996 1835 1843
    • (1996) Genes Dev. , vol.10 , pp. 1835-1843
    • Liu, C.Y.1    Flesken-Nikitin, A.2    Li, S.3    Zeng, Y.4    Lee, W.H.5
  • 119
    • 0030924656 scopus 로고    scopus 로고
    • Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
    • T. Ludwig, D.L. Chapman, V.E. Papaioannou, and A. Efstratiadis Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos Genes Dev. 11 1997 1226 1241
    • (1997) Genes Dev. , vol.11 , pp. 1226-1241
    • Ludwig, T.1    Chapman, D.L.2    Papaioannou, V.E.3    Efstratiadis, A.4
  • 124
    • 0037773540 scopus 로고    scopus 로고
    • Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability
    • E.E. McCarthy, J.T. Celebi, R. Baer, and T. Ludwig Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability Mol. Cell. Biol. 23 2003 5056 5063
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5056-5063
    • McCarthy, E.E.1    Celebi, J.T.2    Baer, R.3    Ludwig, T.4
  • 126
    • 0034609744 scopus 로고    scopus 로고
    • Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro
    • M. Bemark, A.A. Khamlichi, S.L. Davies, and M.S. Neuberger Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro Curr. Biol. 10 2000 1213 1216
    • (2000) Curr. Biol. , vol.10 , pp. 1213-1216
    • Bemark, M.1    Khamlichi, A.A.2    Davies, S.L.3    Neuberger, M.S.4
  • 129
    • 0034609725 scopus 로고    scopus 로고
    • Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality
    • G. Esposito, I. Godindagger, U. Klein, M.L. Yaspo, A. Cumano, and K. Rajewsky Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality Curr. Biol. 10 2000 1221 1224
    • (2000) Curr. Biol. , vol.10 , pp. 1221-1224
    • Esposito, G.1    Godindagger, I.2    Klein, U.3    Yaspo, M.L.4    Cumano, A.5    Rajewsky, K.6
  • 131
    • 5044248228 scopus 로고    scopus 로고
    • Unpublished observations.
    • H. Ohmori, Unpublished observations.
    • Ohmori, H.1
  • 133
    • 0033974775 scopus 로고    scopus 로고
    • Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally
    • G. Esposito, G. Texido, U.A. Betz, H. Gu, W. Muller, U. Klein, and K. Rajewsky Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally Proc. Natl. Acad. Sci. U.S.A. 97 2000 1166 1171
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 1166-1171
    • Esposito, G.1    Texido, G.2    Betz, U.A.3    Gu, H.4    Muller, W.5    Klein, U.6    Rajewsky, K.7
  • 138
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • C. Deng, P. Zhang, J.W. Harper, S.J. Elledge, and P. Leder Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control Cell 82 1995 675 684
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 140
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth control
    • Y. Xu, and D. Baltimore Dual roles of ATM in the cellular response to radiation and in cell growth control Genes Dev. 10 1996 2401 2410
    • (1996) Genes Dev. , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 141
    • 0029844048 scopus 로고    scopus 로고
    • Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
    • Y. Xu, T. Ashley, E.E. Brainerd, R.T. Bronson, M.S. Meyn, and D. Baltimore Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma Genes Dev. 10 1996 2411 2422
    • (1996) Genes Dev. , vol.10 , pp. 2411-2422
    • Xu, Y.1    Ashley, T.2    Brainerd, E.E.3    Bronson, R.T.4    Meyn, M.S.5    Baltimore, D.6
  • 142
    • 0030713080 scopus 로고    scopus 로고
    • Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles
    • C. Barlow, M. Liyanage, P.B. Moens, C.X. Deng, T. Ried, and A. Wynshaw-Boris Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles Nat. Genet. 17 1997 462 466
    • (1997) Nat. Genet. , vol.17 , pp. 462-466
    • Barlow, C.1    Liyanage, M.2    Moens, P.B.3    Deng, C.X.4    Ried, T.5    Wynshaw-Boris, A.6
  • 143
    • 0030667522 scopus 로고    scopus 로고
    • Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
    • C. Barlow, K.D. Brown, C.X. Deng, D.A. Tagle, and A. Wynshaw-Boris Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways Nat. Genet. 17 1997 453 456
    • (1997) Nat. Genet. , vol.17 , pp. 453-456
    • Barlow, C.1    Brown, K.D.2    Deng, C.X.3    Tagle, D.A.4    Wynshaw-Boris, A.5
  • 144
    • 0031474756 scopus 로고    scopus 로고
    • Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice
    • Y.A. Wang, A. Elson, and P. Leder Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice Proc. Natl. Acad. Sci. U.S.A. 94 1997 14590 14595
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 14590-14595
    • Wang, Y.A.1    Elson, A.2    Leder, P.3
  • 145
    • 0031806910 scopus 로고    scopus 로고
    • Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice
    • Y. Xu, E.M. Yang, J. Brugarolas, T. Jacks, and D. Baltimore Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice Mol. Cell. Biol. 18 1998 4385 4390
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4385-4390
    • Xu, Y.1    Yang, E.M.2    Brugarolas, J.3    Jacks, T.4    Baltimore, D.5
  • 146
    • 0033563099 scopus 로고    scopus 로고
    • Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
    • M.J. Liao, and T. Van Dyke Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma Genes Dev. 13 1999 1246 1250
    • (1999) Genes Dev. , vol.13 , pp. 1246-1250
    • Liao, M.J.1    Van Dyke, T.2
  • 147
    • 0034102337 scopus 로고    scopus 로고
    • ATR disruption leads to chromosomal fragmentation and early embryonic lethality
    • E.J. Brown, and D. Baltimore ATR disruption leads to chromosomal fragmentation and early embryonic lethality Genes Dev. 14 2000 397 402
    • (2000) Genes Dev. , vol.14 , pp. 397-402
    • Brown, E.J.1    Baltimore, D.2
  • 152
    • 5044246325 scopus 로고    scopus 로고
    • Unpublished observations.
    • J.H.J.H., H.P. Roest, et al., Unpublished observations.
    • Roest, H.P.1
  • 154
    • 0032213939 scopus 로고    scopus 로고
    • Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene
    • N. Chester, F. Kuo, C. Kozak, C.D. O'Hara, and P. Leder Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene Genes Dev. 12 1998 3382 3393
    • (1998) Genes Dev. , vol.12 , pp. 3382-3393
    • Chester, N.1    Kuo, F.2    Kozak, C.3    O'Hara, C.D.4    Leder, P.5


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