Enhanced intestinal adenomatous polyp formation in Pms2(-/-);Min mice

Cancer Research

Volumn 58, Issue 6, 1998, Pages 1087-1089

  Baker, Sean M ^c   Harris, Allie C ^a   Tsao, Jen Lan ^d   Flath, Tom J ^a   Bronner, C Eric ^a   Gordon, Melissa ^b   Shibata, Darryl ^d   Liskay, R Michael ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; FAMILIAL CANCER; GENE MUTATION; HETEROZYGOSITY LOSS; INTESTINE POLYP; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ADENOSINE TRIPHOSPHATASES; ANIMALS; CYTOSKELETAL PROTEINS; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; INTESTINAL POLYPS; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICROSATELLITE REPEATS; NEOPLASMS, EXPERIMENTAL; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTEINS;

EID: 0032521201     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
2. Modrich, P., and Lahue, R. Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem., 65: 101-133, 1996.
3. Fishel, R., and Kolodner, R. D. Identification of mismatch repair genes and their role in the development of cancer. Curr. Opin. Genet. Dev., 5: 382-395, 1995.
4. Watson, P., and Lynch, H. T. Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer (Phila.), 71: 677-685, 1993.
5. Risinger, J. I., Barrett, J. C., Watson, P., Lynch, H. T., and Boyd, J. Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome. Cancer (Phila.), 77: 1836-1843, 1996.
6. Strand, M., Prolla, T. A., Liskay, R. M., and Petes, T. D. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature (Lond.), 365: 274-276, 1993.
7. Baker, S. M., Bronner, C. E., Zhang, L., Plug, A. W., Robatzek, M., Warren, G., Elliott, E. A., Yu, J., Ashley, T., Arnheim, N., Flavell, R. A., and Liskay, R. M. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell, 82: 309-319, 1995.
8. Baker, S. M., Plug, A. W., Prolla, T. A., Bronner, C. E., Harris, A. C., Yao, X., Christie, D. M., Monell, C., Arnheim, N., Bradley, A., Ashley, T., and Liskay, R. M. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat. Genet., 13: 336-342, 1996.
9. de Wind, N., Dekker, M., Berns, A., Radman, M., and te Riele, H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell, 82: 321-330, 1995.
10. Reitmair, A. H., Redston, M., Cai, J. C., Chuang, T. C., Bjerknes, M., Cheng, H., Hay, K., Gallinger, S., Bapat, B., and Mak, T. W. Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice. Cancer Res., 56: 3842-3849, 1996.
11. Su, L-K., Kinzler, K. W., Vogelstein, B., Preisinger, A. C., Rapaich Moser, A. R., Luongo, C., Gould, K. A., and Dove, W. F. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science (Washington DC), 256: 668-670, 1992.
12. Moser, A. R., Dove, W. F., Roth, K. A., and Gordon, J. I. The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system. J. Cell Biol., 116: 1517-1526, 1992.
13. Reitmair, A. H., Cai, J. C., Bjerknes, M., Redston, M., Cheng, H., Pind, M. T., Hay, K., Mitri, A., Bapat, B. V., Mak, T. W., and Gallinger, S. MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis. Cancer Res., 56: 2922-2926, 1996.
14. Dietrich, W. F., Lander, E. S., Smith, J. S., Moser, A. R., Gould, K. A., Luongo, C., Borenstein, N., and Dove, W. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell, 75: 631-639, 1993.
15. Tsao, J. L., Davis, S. D., Baker, S. M., Liskay, R. M., and Shibata, D. Intestinal stem cell division and genetic diversity. A computer and experimental analysis. Am. J Pathol., 151: 573-579, 1997.
16. Shi, S. R., Key, M. E., and Kalra, K. L. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J. Histochem. Cytochem., 39: 741-748, 1991.
17. Shoemaker, A. R., Moser, A. R., and Dove, W. F. N-Ethyl-N-nitrosourea treatment of multiple intestinal neoplasia (Min) mice: age-related effects on the formation of intestinal adenomas, cystic crypts, and epidermoid cysts. Cancer Res., 55: 4479-4485, 1995.
18. Huang, J., Papadopoulos, N., McKinley, A. J., Farrington, S. M., Curtis, L. J., Wyllie, A. H., Zheng, S., Wilson, J. K. V., Markowitz, S. D., Morin, P., Kinzler, K. W., Vogelstein, B., and Dunlop, M. G. APC mutations in colorectal tumours with mismatch repair deficiency. Proc. Natl. Acad. Sci. USA, 93: 9049-9054, 1996.
19. + in intestinal adenomas from Min mice. Cancer Res., 54: 5947-5952, 1994.
20. Min-induced intestinal neoplasia. Cell, 81: 957-966, 1995.
21. Narayanan, L., Fritzell, J. A., Baker, S. M., Liskay, R. M., and Glazer, P. M. Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2. Proc. Natl. Acad. Sci. USA, 94: 3122-3127, 1997.