Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 2301-2304

  Masutani, Mitsuko ^a   Suzuki, Hiroshi ^b   Kamada, Nobuo ^b   Watanabe, Miho ^b   Ueda, Otoya ^b   Nozaki, Tadashige ^a   Jishage, Kou Ichi ^b   Watanabe, Takeshi ^b   Sugimoto, Tetsuro ^b   Nakagama, Hitoshi ^a   Ochiya, Takahiro ^a   Sugimura, Takashi ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Gene targeting; Insulin dependent diabetes mellitus; Islet celi; NAD

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; DNA STRAND; ENZYME ACTIVITY; GENE DISRUPTION; GENE TARGETING; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EXONS; IMMUNITY, NATURAL; ISLETS OF LANGERHANS; MICE; MICE, KNOCKOUT; NAD; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINATION, GENETIC; STREPTOZOCIN;

ANIMALIA;

EID: 13044270976     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.2301     Document Type: Article

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