DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 7, 2004, Pages 2052-2057

  Itoh, Toshiki ^a   Cado, Dragana ^a   Kamide, Ryoichi ^b   Linn, Stuart ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CASPASE; CASPASE 3; DIMETHYLBENZ[A]ANTHRACENE; DNA BINDING PROTEIN; P48 XERODERMA PIGMENTOSUM PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; DDB2 GENE; DRUG EFFECT; EMBRYO; FIBROBLAST; GENE; GENE DELETION; GENE DISRUPTION; GENE FUNCTION; GENE MUTATION; GENETICS; HETEROZYGOSITY; HUMAN; METABOLISM; MOUSE; NEWBORN; NONHUMAN; NUTRITIONAL DEFICIENCY; PATHOLOGY; PHENOTYPE; PRIORITY JOURNAL; RADIATION EXPOSURE; SKIN CANCER; SKIN CARCINOGENESIS; SKIN TUMOR; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; APOPTOSIS; CARCINOGENS; CASPASE 3; CASPASES; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; FIBROBLASTS; GENE DELETION; MICE; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 1242296809     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306551101     Document Type: Article

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