The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis

Cancer Research

Volumn 61, Issue 21, 2001, Pages 7934-7942

  Kuraguchi, Mari ^a   Yang, Kan ^a   Wong, Edmund ^c   Avdievich, Elena ^c   Edelmann, Winfried ^c   Kolodner, Richard D ^e,f   Lipkin, Martin ^a   Brown, Anthony M C ^a,b   Kucherlapati, Raju ^d  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Departments of Cell Biology   (United States)

^d Quest Diagnostics   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GENE PRODUCT; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SEQUENCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; CANCER INCIDENCE; CARCINOGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; DNA REPAIR; FEMALE; FRAMESHIFT MUTATION; GENE CONTROL; GENE MUTATION; GENE REPRESSION; INTESTINE TUMOR; MALE; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STOP CODON; SURVIVAL RATE; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE PAIR MISMATCH; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; GENES, APC; GENETIC PREDISPOSITION TO DISEASE; INBREEDING; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICROSATELLITE REPEATS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION;

EID: 0035503172     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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