DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

Mutagenesis

Volumn 14, Issue 3, 1999, Pages 339-347

  Glassner, Brian J ^a   Weeda, Geert ^b   Allan, James M ^a   Broekhof, Jose' L M ^b   Carls, Nick H E ^a   Donker, Ingrid ^b   Engelward, Bevin P ^e   Hampson, Richard J ^a   Hersmus, Remko ^c   Hickman, Mark J ^a   Roth, Richard B ^a   Warren, Henry B ^d   Wu, Mavis M ^a   Hoeijmakers, Jan H J ^b   Samson, Leona D ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^d HARVARD MEDICAL SCHOOL   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CARMUSTINE; CYSTEINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MITOMYCIN C; MUTANT PROTEIN; PROTECTIVE AGENT; STREPTOZOCIN; TEMOZOLOMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BONE MARROW CELL; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DRUG CYTOTOXICITY; ENZYME ACTIVITY; FIBROBLAST; GENE DELETION; HEMATOPOIETIC TISSUE; LD 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

ANIMALIA; MURINAE;

EID: 0032892044     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.3.339     Document Type: Article

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