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Volumn 64, Issue 2, 2004, Pages 517-522

An Msh2 Point Mutation Uncouples DNA Mismatch Repair and Apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; CISPLATIN; PROTEIN MSH2;

EID: 9144227402     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-2957     Document Type: Article
Times cited : (161)

References (52)
  • 1
    • 0030882381 scopus 로고    scopus 로고
    • Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study
    • The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer
    • Peltomaki, P., and Vasen, H. F. Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. Gastroenterology, 113: 1146-1158, 1997.
    • (1997) Gastroenterology , vol.113 , pp. 1146-1158
    • Peltomaki, P.1    Vasen, H.F.2
  • 2
    • 0029784320 scopus 로고    scopus 로고
    • Biochemistry and genetics of eukaryotic mismatch repair
    • Kolodner, R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev., 10: 1433-1442, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 1433-1442
    • Kolodner, R.1
  • 3
    • 0030803659 scopus 로고    scopus 로고
    • Strand-specific mismatch repair in mammalian cells
    • Modrich, P. Strand-specific mismatch repair in mammalian cells. J. Biol. Chem., 272: 24727-24730, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24727-24730
    • Modrich, P.1
  • 5
    • 0028533694 scopus 로고
    • DNA damage tolerance, mismatch repair and genome instability
    • Karran, P., and Bignami, M. DNA damage tolerance, mismatch repair and genome instability. Bioessays, 16: 833-839, 1994.
    • (1994) Bioessays , vol.16 , pp. 833-839
    • Karran, P.1    Bignami, M.2
  • 7
    • 0030776227 scopus 로고    scopus 로고
    • Correction of hypermutability, N-methyl-N′ -nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
    • Umar, A., Koi, M., Risinger, J. I., Glaab, W. E., Tindall, K. R., Kolodner, R. D., Boland, C. R., Barrett, J. C., and Kunkel, T. A. Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res., 57: 3949-3955, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3949-3955
    • Umar, A.1    Koi, M.2    Risinger, J.I.3    Glaab, W.E.4    Tindall, K.R.5    Kolodner, R.D.6    Boland, C.R.7    Barrett, J.C.8    Kunkel, T.A.9
  • 9
    • 0032851842 scopus 로고    scopus 로고
    • Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
    • Hickman, M. J., and Samson. L. D. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc. Natl. Acad. Sci. USA, 96: 10764-10769, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10764-10769
    • Hickman, M.J.1    Samson, L.D.2
  • 11
    • 0033197818 scopus 로고    scopus 로고
    • MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae
    • Ni, T. T., Marsischky, G. T., and Kolodner, R. D. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Mol. Cell. 4: 439-444, 1999.
    • (1999) Mol. Cell. , vol.4 , pp. 439-444
    • Ni, T.T.1    Marsischky, G.T.2    Kolodner, R.D.3
  • 13
    • 0029812676 scopus 로고    scopus 로고
    • Cisplatin and Adriamycin resistance are associated with MutLα and mismatch repair deficiency in an ovarian tumor cell line
    • Drummond, J. T., Anthoney, A., Brown, R., and Modrich, P. Cisplatin and Adriamycin resistance are associated with MutLα and mismatch repair deficiency in an ovarian tumor cell line. J. Biol. Chem., 271: 19645-19648, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19645-19648
    • Drummond, J.T.1    Anthoney, A.2    Brown, R.3    Modrich, P.4
  • 14
    • 0031783825 scopus 로고    scopus 로고
    • Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus
    • Glaab, W. E., Risinger, J. I., Umar, A., Barrett, J. C., Kunkel, T. A., and Tindall, K. R. Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus. Carcinogenesis (Lond.), 19: 1931-1937, 1998.
    • (1998) Carcinogenesis (Lond.) , vol.19 , pp. 1931-1937
    • Glaab, W.E.1    Risinger, J.I.2    Umar, A.3    Barrett, J.C.4    Kunkel, T.A.5    Tindall, K.R.6
  • 16
    • 0035886816 scopus 로고    scopus 로고
    • The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: Revising the mutator hypothesis
    • Fishel, R. The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis. Cancer Res., 61: 7369-7374, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 7369-7374
    • Fishel, R.1
  • 18
    • 0025363116 scopus 로고
    • Superfamily of UvrA-related NTP-binding proteins. Implications for rational classification of recombination/repair systems
    • Gorbalenya, A. E., and Koonin, E. V. Superfamily of UvrA-related NTP-binding proteins. Implications for rational classification of recombination/repair systems. J. Mol. Biol., 213: 583-591, 1990.
    • (1990) J. Mol. Biol. , vol.213 , pp. 583-591
    • Gorbalenya, A.E.1    Koonin, E.V.2
  • 19
    • 0025310575 scopus 로고
    • Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 Å resolution: Implications for the mechanism of GTP hydrolysis
    • Pai, E. F., Krengel, U., Petsko, G. A., Goody, R. S., Kabsch, W., and Wittinghofer, A. Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 Å resolution: implications for the mechanism of GTP hydrolysis. EMBO J., 9: 2351-2359, 1990.
    • (1990) EMBO J. , vol.9 , pp. 2351-2359
    • Pai, E.F.1    Krengel, U.2    Petsko, G.A.3    Goody, R.S.4    Kabsch, W.5    Wittinghofer, A.6
  • 20
    • 0001607723 scopus 로고
    • Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker, J. E., Saraste, M., Runswick, M. J., and Gay, N. J. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J., 1: 945-951, 1982.
    • (1982) EMBO J. , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 21
    • 0027980253 scopus 로고
    • Dominant negative mutator mutations in the mutS gene of Escherichia coli
    • Wu, T. H., and Marinus, M. G. Dominant negative mutator mutations in the mutS gene of Escherichia coli. J. Bacteriol., 176: 5393-5400, 1994.
    • (1994) J. Bacteriol. , vol.176 , pp. 5393-5400
    • Wu, T.H.1    Marinus, M.G.2
  • 22
    • 0030962031 scopus 로고    scopus 로고
    • Genetic and biochemical analysis of Msh2p-Msh6p: Role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition
    • Alani, E., Sokolsky, T., Studamire, B., Miret, J. J., and Lahue, R. S. Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Mol. Cell. Biol., 17: 2436-2447, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2436-2447
    • Alani, E.1    Sokolsky, T.2    Studamire, B.3    Miret, J.J.4    Lahue, R.S.5
  • 23
    • 0032079736 scopus 로고    scopus 로고
    • hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα
    • Iaccarino, I., Marra, G., Palombo, F., and Jiricny, J. hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα. EMBO J., 17: 2677-2686, 1998.
    • (1998) EMBO J. , vol.17 , pp. 2677-2686
    • Iaccarino, I.1    Marra, G.2    Palombo, F.3    Jiricny, J.4
  • 25
    • 0034641938 scopus 로고    scopus 로고
    • Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
    • Obmolova, G., Ban, C., Hsieh, P., and Yang, W. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature (Lond.), 407: 703-710, 2000.
    • (2000) Nature (Lond.) , vol.407 , pp. 703-710
    • Obmolova, G.1    Ban, C.2    Hsieh, P.3    Yang, W.4
  • 26
    • 0031664853 scopus 로고    scopus 로고
    • A new logic for DNA engineering using recombination in Escherichia coli
    • Zhang, Y., Buchholz, F., Muyrers, J. P., and Stewart, A. F. A new logic for DNA engineering using recombination in Escherichia coli. Nat. Genet., 20: 123-128, 1998.
    • (1998) Nat. Genet. , vol.20 , pp. 123-128
    • Zhang, Y.1    Buchholz, F.2    Muyrers, J.P.3    Stewart, A.F.4
  • 27
    • 0029091809 scopus 로고
    • WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras
    • Ioffe, E., Liu, Y., Bhaumik, M., Poirier, F., Factor, S. M., and Stanley, P. WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc. Natl. Acad. Sci. USA. 92: 7357-7361, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7357-7361
    • Ioffe, E.1    Liu, Y.2    Bhaumik, M.3    Poirier, F.4    Factor, S.M.5    Stanley, P.6
  • 29
    • 0029085739 scopus 로고
    • Measurement of heteroduplex repair in human cell extracts
    • E. C. Friedberg (ed.). New York: Academic Press
    • Thomas, D. C., Umar, A., and Kunkel, T. A. Measurement of heteroduplex repair in human cell extracts. In: E. C. Friedberg (ed.), Methods: A Companion to Methods in Enzymology, pp. 187-197. New York: Academic Press, 1995.
    • (1995) Methods: A Companion to Methods in Enzymology , pp. 187-197
    • Thomas, D.C.1    Umar, A.2    Kunkel, T.A.3
  • 32
    • 0029868110 scopus 로고    scopus 로고
    • Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
    • Marsischky, G. T., Filosi, N., Kane, M. F., and Kolodner, R. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev., 10: 407-420, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 407-420
    • Marsischky, G.T.1    Filosi, N.2    Kane, M.F.3    Kolodner, R.4
  • 33
    • 0029659046 scopus 로고    scopus 로고
    • hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
    • Palombo, F., Iaccarino, I., Nakajima, E., Ikejima, M., Shimada, T., and Jiricny, J. hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol., 6: 1181-1184, 1996.
    • (1996) Curr. Biol. , vol.6 , pp. 1181-1184
    • Palombo, F.1    Iaccarino, I.2    Nakajima, E.3    Ikejima, M.4    Shimada, T.5    Jiricny, J.6
  • 34
    • 0032584384 scopus 로고    scopus 로고
    • Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
    • Genschel, J., Littman, S. J., Drummond, J. T., and Modrich, P. Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα. J. Biol. Chem., 273: 19895-19901, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19895-19901
    • Genschel, J.1    Littman, S.J.2    Drummond, J.T.3    Modrich, P.4
  • 35
    • 0031769438 scopus 로고    scopus 로고
    • Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: Examination of mutations found in hereditary nonpolyposis colorectal cancer
    • Guerrette, S., Wilson, T., Gradia, S., and Fishel, R. Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer. Mol. Cell. Biol., 18: 6616-6623, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6616-6623
    • Guerrette, S.1    Wilson, T.2    Gradia, S.3    Fishel, R.4
  • 37
    • 0035503172 scopus 로고    scopus 로고
    • The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
    • Kuraguchi, M., Yang, K., Wong, E., Avdievich, E., Fan, K., Kolodner, R. D., Lipkin, M., Brown, A. M., Kucherlapati, R., and Edelmann, W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res., 61: 7934-7942, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 7934-7942
    • Kuraguchi, M.1    Yang, K.2    Wong, E.3    Avdievich, E.4    Fan, K.5    Kolodner, R.D.6    Lipkin, M.7    Brown, A.M.8    Kucherlapati, R.9    Edelmann, W.10
  • 43
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin, G. R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA, 78: 7634-7638, 1981.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 46
    • 0043290038 scopus 로고    scopus 로고
    • DNA repair and tumorigenesis: Lessons from hereditary cancer syndromes
    • Heinen, C. D., Schmutte, C., and Fishel, R. DNA repair and tumorigenesis: lessons from hereditary cancer syndromes. Cancer Biol. Ther., 1: 477-485, 2002.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 477-485
    • Heinen, C.D.1    Schmutte, C.2    Fishel, R.3
  • 47
    • 0033290537 scopus 로고    scopus 로고
    • The role of mismatch repair in DNA damage-induced apoptosis
    • Li, G. M. The role of mismatch repair in DNA damage-induced apoptosis. Oncol. Res., 11: 393-400, 1999.
    • (1999) Oncol. Res. , vol.11 , pp. 393-400
    • Li, G.M.1
  • 48
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
    • Kat, A., Thilly, W. G., Fang, W. H., Longley, M. J., Li, G. M., and Modrich, P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl. Acad. Sci. USA, 90: 6424-6428, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.H.3    Longley, M.J.4    Li, G.M.5    Modrich, P.6
  • 50
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong, J. G., Costanzo, A., Yang, H. Q., Melino, G., Kaelin, W. G., Jr., Levrero, M., and Wang, J. Y. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature (Lond.), 399: 806-809, 1999.
    • (1999) Nature (Lond.) , vol.399 , pp. 806-809
    • Gong, J.G.1    Costanzo, A.2    Yang, H.Q.3    Melino, G.4    Kaelin Jr., W.G.5    Levrero, M.6    Wang, J.Y.7
  • 51
    • 0344284564 scopus 로고    scopus 로고
    • Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
    • Shimodaira, H., Yoshioka-Yamashita, A., Kolodner, R. D., and Wang, J. Y. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc. Natl. Acad. Sci. USA, 100: 2420-2425, 2003.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2420-2425
    • Shimodaira, H.1    Yoshioka-Yamashita, A.2    Kolodner, R.D.3    Wang, J.Y.4
  • 52
    • 0025777777 scopus 로고
    • Heteroduplex repair in extracts of human HeLa cells
    • Thomas, D. C., Roberts, J. D., and Kunkel, T. A. Heteroduplex repair in extracts of human HeLa cells. J. Biol. Chem., 266: 3744-3751, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3744-3751
    • Thomas, D.C.1    Roberts, J.D.2    Kunkel, T.A.3


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