Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 13, 1999, Pages 7376-7381

  Luo, Guangbin ^a   Yao, Michelle S ^b   Bender, Carla F ^b   Mills, Michael ^a   Bladl, Anthony R ^b   Bradley, Allan ^a   Petrini, John H J ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL VIABILITY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; EMBRYO; EMBRYO DEVELOPMENT; GENOTYPE; IONIZING RADIATION; LETHALITY; MOUSE; MUTATION; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; SACCHAROMYCES CEREVISIAE; STEM CELL;

ANIMALS; CELL DEATH; DNA-BINDING PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MUTATION; SACCHAROMYCES CEREVISIAE PROTEINS; STEM CELLS;

ANIMALIA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033594904     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.13.7376     Document Type: Article

References (42)

1. Kanaar, R. & Hoeijmakers, J. H. J. (1997) Genes Funct. 1, 165-174.
2. Petrini, J. H., Bressan, D. A. & Yao, M. S. (1997) Semin. Immunol. 9, 181-188.
3. Haber, J. E. (1998) Cell 95, 583-586.
4. Tsukamoto, Y., Kato, J. & Ikeda, H. (1996) Genetics 142, 383-391.
5. Milne, G. T., Jin, S., Shannon, K. B. & Weaver, D. T. (1996) Mol. Cell. Biol. 16, 4189-4198.
6. Boulton, S. J. & Jackson, S. P. (1996) EMBO J. 15, 5093-5103.
7. Moore, J. K. & Haber, J. E. (1996) Mol. Cell. Biol. 16, 2164-2173.
8. Roeder, G. S. (1997) Genes Dev. 11, 2600-2621.
9. Lee, S. E., Moore, J. K., Holmes, A., Umezu, K., Kolodner, R. D. & Haber, J. E. (1998) Cell 94, 399-409.
10. Kironmai, K. M. & Muniyappa, K. (1997) Genes Cells 2, 443-455.
11. Nelms, B. E., Maser, R. S., MacKay, J. F., Lagally, M. G. & Petrini, J. H. J. (1998) Science 280, 590-592.
12. Nove, J., Little, J. B., Mayer, P. J., Troilo, P. & Nichols, W. W. (1986) Mutat. Res. 163, 255-262.
13. Paull, T. T. & Gellert, M. (1998) Mol. Cell 1, 969-979.
14. Carney, J. P., Maser, R. S., Olivares, H., Davis, E. M., Le Beau, M., Yates, J. R., III, Hays, L., Morgan, W. F. & Petrini, J. H. J. (1998) Cell 93, 477-486.
15. Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K. M., Chrzanowska, K. H., Saar, K., Beckmann, G., Seemanova, E., Cooper, P. R., Nowak, N. J., et al. (1998) Cell 93, 467-476.
16. Soriano, P., Montgomery, C., Geske, R. & Bradley, A. (1991) Cell 64, 693-702.
17. Petrini, J. H. J., Xiao, Y.-H. & Weaver, D. T. (1995) Mol. Cell. Biol. 15, 4304-4308.
18. Ramirez-Solis, R., Liu, P. & Bradley, A. (1995) Nature (London) 378, 720-724.
19. McMahon, A. P. & Bradley, A. (1990) Cell 62, 1073-1085.
20. Ramirez-Solis, R., Rivera-Perez, J., Wallace, J. D., Wims, M., Zheng, H. & Bradley, A. (1992) Anal. Biochem. 201, 331-335.
21. Dolganov, G. M., Maser, R. S., Novikov, A., Tosto, L., Chong, S., Bressan, D. A. & Petrini, J. H. J. (1996) Mol. Cell. Biol. 16, 4832-4841.
22. Kaufman, M. H. (1992) The Atlas of Mouse Development (Academic, London).
23. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. (1992) J. Cell Biol. 119, 493-501.
24. Hayashi, Y., Koike, M., Matsutani, M. & Hoshino, T. (1988) J. Histochem. Cytochem. 36, 511-514.
25. Sharan, S. K., Morimatsu, M., Albrecht, U., Lim, D. S., Regel, E., Dinh, C., Sands, A., Eichele, G., Hasty, P. & Bradley, A. (1997) Nature (London) 386, 804-810.
26. Alani, E., Padmore, R. & Kleckner, N. (1990) Cell 61, 419-436.
27. Xiao, Y. & Weaver, D. T. (1997) Nucleic Acids Res. 25, 2985-2991.
28. Shiloh, Y. (1997) Annu. Rev. Genet. 31, 635-662.
29. Nussenzweig, A., Chen, C., da Costa Soares, V., Sanchez, M., Sokol, K., Nussenzweig, M. C. & Li, G. C. (1996) Nature (London) 382, 551-555.
30. Taccioli, G. E., Gottlieb, T. M., Blunt, T., Priestley, A., Demengeot, J., Mizuta, R., Lehmann, A. R., Alt, F. W., Jackson, S. P. & Jeggo, P. A. (1994) Science 265, 1442-1445.
31. Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, G. C., Demengeot, J., Gottlieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A. & Jackson, S. P. (1995) Cell 80, 813-823.
32. Kirchgessner, C. U., Patil, C. K., Evans, J. W., Cuomo, C. A., Fried, L. M., Carter, T., Oettinger, M. A. & Brown, J. M. (1995) Science 267, 1178-1183.
33. Grawunder, U., Zimmer, D., Fugmann, S., Schwarz, K. & Lieber, M. R. (1998) Mol. Cell 2, 477-484.
34. Li, Z., Otevrel, T., Gao, Y., Cheng, H.-L., Seed, B., Stamato, T. D., Taccioli, G. E. & Alt, F. W. (1995) Cell 83, 1079-1089.
35. Ivanov, E. L., Korolev, V. G. & Fabre, F. (1992) Genetics 132, 651-664.
36. Fabre, F., Boulet, A. & Roman, H. (1984) Mol. Gen. Genet. 195, 139-143.
37. Hogan, B. (1994) Manipulating the Mouse Embryo: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
38. Leach, D. R. (1994) BioEssays 16, 893-900.
39. Cox, M. M. (1998) Genes Cells 3, 65-78.
40. Sonoda, E., Sasaki, M. S., Buerstedde, J. M., Bezzubova, O., Shinohara, A., Ogawa, H., Takata, M., Yamaguchi-Iwai, Y. & Takeda, S. (1998) EMBO J. 17, 598-608.
41. Lim, D. S. & Hasty, P. (1996) Mol. Cell. Biol. 16, 7133-7143.
42. Tsuzuki, T., Fujii, Y., Sakumi, K., Tominaga, Y., Nakao, K., Sekiguchi, M., Matsushiro, A., Yoshimura, Y. & Morita, T. (1996) Proc. Natl. Acad. Sci. USA 93, 6236-6240.