Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 24, 1997, Pages 12869-12874

  Hang, B ^a   Singer, B ^a   Margison, G P ^b   Elder, R H ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE DERIVATIVE; ALKYLPURINE DNA N GLYCOSYLASE; CARMUSTINE; HYPOXANTHINE DERIVATIVE; MITOMYCIN C; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; DEAMINATION; DNA REPAIR; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME SPECIFICITY; GENETIC STABILITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ADENINE; ANIMALS; CELL-FREE SYSTEM; CYTOSINE; DNA GLYCOSYLASES; DNA REPAIR; GUANINE; HYDROLYSIS; HYPOXANTHINE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; N-GLYCOSYL HYDROLASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0030707950     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.24.12869     Document Type: Article

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