Synergistic interactions between XPC and p53 mutations in double-mutant mice: Neural tube abnormalities and accelerated UV radiation-induced skin cancer

Current Biology

Volumn 6, Issue 12, 1996, Pages 1691-1694

  Cheo, David L ^a   Meira, Lisiane B ^a   Hammer, Robert E ^b   Burns, Dennis K ^a   Doughty, Ana T B ^a   Friedberg, Errol C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0030480945     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)70794-X     Document Type: Article

References (15)

1. Friedberg EC, Walker GC, Siede W: DNA Repair and Mutagenesis. Washington DC: American Society for Microbiology; 1995.
2. Cleaver JE, Kraemer KH. Xeroderma pigmentosum. In The Metabolic Basis of Inherited Disease.Vol. II. Edited by Scriver CR, Beaudet AL, Sly WS, Valle D. New York: McGraw-Hill; 1989:2949-2971.
3. Nakane H, Takeuchi S, Yuba S, Saijo M, Nakatsu Y, Murai H, et al.: High incidence of ultraviolet-B- or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene. Nature 1995, 377:165-168.
4. de Vries A, van Oostrom CTM, Hofhuls FMA, Dortant PM, Berg RJW, de Gruijl FR, et al.: Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA Nature 1995, 377:169-173.
5. Sands AT, Abuin A, Sanchez A, Conti JC, Bradley A: High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC. Nature 1995, 377:162-165.
6. Miyashita T, Reed JC: Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80:293-299.
7. Kuerbitz SJ, Plunkett BS, Walsh WV, Kastan MB: Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 1992, 89:7491-7495.
8. Wang XW, Yen H, Schaeffer L, Roy R, Moncollin V, Egly J-M, et al.: p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat Genet 1995, 10:188-194.
9. Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 1991, 253:49-53.
10. Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, et al.: Sunburn and p53 in the onset of skin cancer. Nature 1994, 372:773-776.
11. Kemp JC, Donehower LA, Bradley A, Balmain A: Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 1993, 74:813-822.
12. Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T: A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 1995, 10:175-180.
13. Armstrong JF, Kaufman MH, Harrison DJ, Clarke AR: High-frequency developmental abnormalities in p53-deficient mice. Curr Biol 1995, 5:931-936.
14. Norman MG, Ludwin SK: Congenital malformations of the nervous system. In Textbook of Neuropathology. 2nd edn. Edited by Davis RL, Robertson DM. Baltimore: Williams and Wilkins; 1991:207-280.
15. Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Munsterberg A, et al.: A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 1990, 346:245-250.