Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent

Carcinogenesis

Volumn 17, Issue 6, 1996, Pages 1215-1220

  Tsuzuki, Teruhisa ^a   Sakumi, Kunihiko ^a   Shiraishi, Akiko ^a   Kawate, Hisaya ^a   Igarashi, Hisato ^a   Iwakuma, Tomoo ^a   Tominaga, Yohei ^a   Zhang, Shaomin ^b   Shimizu, Seiichiro ^b   Ishikawa, Takatoshi ^b   Nakamura, Kenji ^a   Nakao, Kazuki ^a   Katsuki, Motoya ^a   Sekiguchi, Mutsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITROSOUREA; METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DEATH; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE MUTATION; GENE TARGETING; HEMATOPOIETIC STEM CELL; LEUKOCYTE COUNT; MOUSE; NONHUMAN; PANCYTOPENIA; PRIORITY JOURNAL; THROMBOCYTE COUNT;

ALKYLATING AGENTS; ANIMALS; CARCINOGENS; DRUG HYPERSENSITIVITY; MALE; METHYLNITROSOUREA; METHYLTRANSFERASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE;

EID: 8944258921     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.6.1215     Document Type: Article

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