Mbd4 inactivation increases C→T transition mutations and promotes gastrointestinal tumor formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 23, 2002, Pages 14937-14942

  Wong, Edmund ^a   Yang, Kan ^b   Kuraguchi, Mari ^b   Werling, Uwe ^a   Avdievich, Elena ^a   Fan, Kunhua ^b   Fazzari, Melissa ^a   Jin, Bo ^a   Brown, Anthony M C ^b,c   Lipkin, Martin ^b   Edelmann, Winfried ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; CPG ISLAND; ENZYME INACTIVATION; FEMALE; GASTROINTESTINAL TUMOR; GENE MUTATION; GENE TARGETING; GENETIC SUSCEPTIBILITY; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE PAIR MISMATCH; BASE SEQUENCE; BLASTOCYST; CHIMERA; CODON, TERMINATOR; CROSSES, GENETIC; DNA PRIMERS; DNA PROBES; DNA REPAIR; ENDODEOXYRIBONUCLEASES; EXONS; FEMALE; FRAMESHIFT MUTATION; GASTROINTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0037069366     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.232579299     Document Type: Article

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