-
1
-
-
0027055770
-
Collaboration of PIM-1 and BCL-2 in lymphomagenesis
-
Acton D., Domen J., Jacobs H., Vlaar M., Korsmeyer S., Berns A. Collaboration of PIM-1 and BCL-2 in lymphomagenesis. Current Topics in Microbiology and Immunology. 182:1992;293-298
-
(1992)
Current Topics in Microbiology and Immunology
, vol.182
, pp. 293-298
-
-
Acton, D.1
Domen, J.2
Jacobs, H.3
Vlaar, M.4
Korsmeyer, S.5
Berns, A.6
-
2
-
-
10744232926
-
Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim
-
Akiyama T., Bouillet P., Miyazaki T., Kadono Y., Chikuda H., Chung U.I., Fukuda A., Hikita A., Seto H., Okada T., et al. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. Embo Journal. 22:2003;6653-6664
-
(2003)
Embo Journal
, vol.22
, pp. 6653-6664
-
-
Akiyama, T.1
Bouillet, P.2
Miyazaki, T.3
Kadono, Y.4
Chikuda, H.5
Chung, U.I.6
Fukuda, A.7
Hikita, A.8
Seto, H.9
Okada, T.10
-
4
-
-
0028212937
-
Apoptosis and its role in human disease
-
Barr P.J., Tomei L.D. Apoptosis and its role in human disease. Biotechnology. 12:1994;487-493
-
(1994)
Biotechnology
, vol.12
, pp. 487-493
-
-
Barr, P.J.1
Tomei, L.D.2
-
5
-
-
0035897415
-
Regulation and localization of the Bloom syndrome protein in response to DNA damage
-
Bischof O., Kim S.H., Irving J., Beresten S., Ellis N.A., Campisi J. Regulation and localization of the Bloom syndrome protein in response to DNA damage. Journal of Cell Biology. 153:2001;367-380
-
(2001)
Journal of Cell Biology
, vol.153
, pp. 367-380
-
-
Bischof, O.1
Kim, S.H.2
Irving, J.3
Beresten, S.4
Ellis, N.A.5
Campisi, J.6
-
7
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., Ricci J.E., Edris W.A., Sutherlin D.P., Green D.R., Salvesen G.S. A unified model for apical caspase activation. Molecular Cell. 11:2003;529-541
-
(2003)
Molecular Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
8
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise L.H., Gonzalez-Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., Mao X., Nuñez G., Thompson C.B. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74:1993;597-608
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
Mao, X.7
Nuñez, G.8
Thompson, C.B.9
-
9
-
-
0028913550
-
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
-
Boldin M.P., Varfolomeev E.E., Pancer Z., Mett I.L., Camonis J.H., Wallach D. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. Journal of Biological Chemistry. 270:1995;7795-7798
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 7795-7798
-
-
Boldin, M.P.1
Varfolomeev, E.E.2
Pancer, Z.3
Mett, I.L.4
Camonis, J.H.5
Wallach, D.6
-
10
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P., Metcalf D., Huang D.C.S., Tarlinton D.M., Kay T.W.H., Köntgen F., Adams J.M., Strasser A. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 286:1999;1735-1738
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.S.3
Tarlinton, D.M.4
Kay, T.W.H.5
Köntgen, F.6
Adams, J.M.7
Strasser, A.8
-
11
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet P., Purton J.F., Godfrey D.I., Zhang L.-C., Coultas L., Puthalakath H., Pellegrini M., Cory S., Adams J.M., Strasser A. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature. 415:2002;922-926
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
Purton, J.F.2
Godfrey, D.I.3
Zhang, L.-C.4
Coultas, L.5
Puthalakath, H.6
Pellegrini, M.7
Cory, S.8
Adams, J.M.9
Strasser, A.10
-
12
-
-
0028812606
-
Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
-
Boyd J.M., Gallo G.J., Elangovan B., Houghton A.B., Malstrom S., Avery B.J., Ebb R.G., Subramanian T., Chittenden T., Lutz R.J., Chinnadurai G. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene. 11:1995;1921-1928
-
(1995)
Oncogene
, vol.11
, pp. 1921-1928
-
-
Boyd, J.M.1
Gallo, G.J.2
Elangovan, B.3
Houghton, A.B.4
Malstrom, S.5
Avery, B.J.6
Ebb, R.G.7
Subramanian, T.8
Chittenden, T.9
Lutz, R.J.10
Chinnadurai, G.11
-
13
-
-
0034712042
-
Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death
-
Chen F., Hersh B.M., Conradt B., Zhou Z., Riemer D., Gruenbaum Y., Horvitz H.R. Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death. Science. 287:2000;1485-1489
-
(2000)
Science
, vol.287
, pp. 1485-1489
-
-
Chen, F.1
Hersh, B.M.2
Conradt, B.3
Zhou, Z.4
Riemer, D.5
Gruenbaum, Y.6
Horvitz, H.R.7
-
14
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan A.M., O'Rourke K., Tewari M., Dixit V.M. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell. 81:1995;505-512
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
15
-
-
0031034997
-
Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
-
Chinnaiyan A.M., O'Rourke K., Lane B.R., Dixit V.M. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science. 275:1997;1122-1126
-
(1997)
Science
, vol.275
, pp. 1122-1126
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Lane, B.R.3
Dixit, V.M.4
-
16
-
-
0344925540
-
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
-
Chipuk J.E., Maurer U., Green D.R., Schuler M. Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell. 4:2003;371-381
-
(2003)
Cancer Cell
, vol.4
, pp. 371-381
-
-
Chipuk, J.E.1
Maurer, U.2
Green, D.R.3
Schuler, M.4
-
17
-
-
0028986876
-
Induction of apoptosis by the Bcl-2 homologue Bak
-
Chittenden T., Harrington E.A., O'Connor R., Flemington C., Lutz R.J., Evan G.I., Guild B.C. Induction of apoptosis by the Bcl-2 homologue Bak. Nature. 374:1995;733-736
-
(1995)
Nature
, vol.374
, pp. 733-736
-
-
Chittenden, T.1
Harrington, E.A.2
O'Connor, R.3
Flemington, C.4
Lutz, R.J.5
Evan, G.I.6
Guild, B.C.7
-
18
-
-
0028824266
-
A novel bcl-2 related gene, bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow
-
Choi S.S., Park I.C., Yun J.W., Sung Y.C., Hong S.I., Shin H.S. A novel bcl-2 related gene, bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. Oncogene. 11:1995;1693-1698
-
(1995)
Oncogene
, vol.11
, pp. 1693-1698
-
-
Choi, S.S.1
Park, I.C.2
Yun, J.W.3
Sung, Y.C.4
Hong, S.I.5
Shin, H.S.6
-
19
-
-
0038702644
-
Bfk: A novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region
-
Coultas L., Pellegrini M., Visvader J.E., Lindeman G.J., Chen L., Adams J.M., Huang D.C., Strasser A. Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region. Cell Death and Differentiation. 10:2003;185-192
-
(2003)
Cell Death and Differentiation
, vol.10
, pp. 185-192
-
-
Coultas, L.1
Pellegrini, M.2
Visvader, J.E.3
Lindeman, G.J.4
Chen, L.5
Adams, J.M.6
Huang, D.C.7
Strasser, A.8
-
20
-
-
0037015397
-
DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53
-
Courtois S., Verhaegh G., North S., Luciani M.G., Lassus P., Hibner U., Oren M., Hainaut P. DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53. Oncogene. 21:2002;6722-6728
-
(2002)
Oncogene
, vol.21
, pp. 6722-6728
-
-
Courtois, S.1
Verhaegh, G.2
North, S.3
Luciani, M.G.4
Lassus, P.5
Hibner, U.6
Oren, M.7
Hainaut, P.8
-
21
-
-
0037123638
-
Premature aging in mice deficient in DNA repair and transcription
-
de Boer J., Andressoo J.O., de Wit J., Huijmans J., Beems R.B., van Steeg H., Weeda G., van der Horst G.T., van Leeuwen W., Themmen A.P., et al. Premature aging in mice deficient in DNA repair and transcription. Science. 296:2002;1276-1279
-
(2002)
Science
, vol.296
, pp. 1276-1279
-
-
De Boer, J.1
Andressoo, J.O.2
De Wit, J.3
Huijmans, J.4
Beems, R.B.5
Van Steeg, H.6
Weeda, G.7
Van Der Horst, G.T.8
Van Leeuwen, W.9
Themmen, A.P.10
-
22
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
Dijkers P.F., Medemadagger R.H., Lammers J.J., Koenderman L., Coffer P.J. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Current Biology. 10:2000;1201-1204
-
(2000)
Current Biology
, vol.10
, pp. 1201-1204
-
-
Dijkers, P.F.1
Medemadagger, R.H.2
Lammers, J.J.3
Koenderman, L.4
Coffer, P.J.5
-
23
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but are susceptible to spontaneous tumours
-
Donehower L.A., Harvey M., Slagle B.L., McArthur M.J., Montgomery C.A.J., Butel J.S., Bradley A. Mice deficient for p53 are developmentally normal but are susceptible to spontaneous tumours. Nature. 356:1992;215-221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, C.A.J.5
Butel, J.S.6
Bradley, A.7
-
25
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C., Fang M., Li Y., Li L., Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 102:2000;33-42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
27
-
-
0028946015
-
Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
-
Farrow S.N., White J.H.M., Martinou I., Raven T., Pun K.-T., Grinham C.J., Martinou J.-C., Brown R. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature. 374:1995;731-733
-
(1995)
Nature
, vol.374
, pp. 731-733
-
-
Farrow, S.N.1
White, J.H.M.2
Martinou, I.3
Raven, T.4
Pun, K.-T.5
Grinham, C.J.6
Martinou, J.-C.7
Brown, R.8
-
28
-
-
0037112844
-
"super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally
-
Garcia-Cao I., Garcia-Cao M., Martin-Caballero J., Criado L.M., Klatt P., Flores J.M., Weill J.C., Blasco M.A., Serrano M. "Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally. Embo Journal. 21:2002;6225-6235
-
(2002)
Embo Journal
, vol.21
, pp. 6225-6235
-
-
Garcia-Cao, I.1
Garcia-Cao, M.2
Martin-Caballero, J.3
Criado, L.M.4
Klatt, P.5
Flores, J.M.6
Weill, J.C.7
Blasco, M.A.8
Serrano, M.9
-
29
-
-
9544250358
-
Bcl-w, a novel member of the bcl-2 family, promotes cell survival
-
Gibson L., Holmgreen S., Huang D.C.S., Bernard O., Copeland N.G., Jenkins N.A., Sutherland G.R., Baker E., Adams J.M., Cory S. bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene. 13:1996;665-675
-
(1996)
Oncogene
, vol.13
, pp. 665-675
-
-
Gibson, L.1
Holmgreen, S.2
Huang, D.C.S.3
Bernard, O.4
Copeland, N.G.5
Jenkins, N.A.6
Sutherland, G.R.7
Baker, E.8
Adams, J.M.9
Cory, S.10
-
30
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
Gray M.D., Shen J.C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., Loeb L.A. The Werner syndrome protein is a DNA helicase. Nature Genetics. 17:1997;100-103
-
(1997)
Nature Genetics
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
Oshima, J.7
Loeb, L.A.8
-
32
-
-
0029790857
-
Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K
-
Han J., Sabbatini P., White E. Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K. Molecular and Cellular Biology. 16:1996;5857-5864
-
(1996)
Molecular and Cellular Biology
, vol.16
, pp. 5857-5864
-
-
Han, J.1
Sabbatini, P.2
White, E.3
-
33
-
-
0035949470
-
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals
-
Han J., Flemington C., Houghton A.B., Gu Z., Zambetti G.P., Lutz R.J., Zhu L., Chittenden T. Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals. Proceedings of the National Academy of Sciences of the USA. 98:2001;11318-11323
-
(2001)
Proceedings of the National Academy of Sciences of the USA
, vol.98
, pp. 11318-11323
-
-
Han, J.1
Flemington, C.2
Houghton, A.B.3
Gu, Z.4
Zambetti, G.P.5
Lutz, R.J.6
Zhu, L.7
Chittenden, T.8
-
34
-
-
0035851204
-
BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons
-
Harris C.A., Johnson E.M. Jr. BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. Journal of Biological Chemistry. 276:2001;37754-37760
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 37754-37760
-
-
Harris, C.A.1
Johnson Jr., E.M.2
-
36
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
Hegde R., Srinivasula S.M., Zhang Z., Wassell R., Mukattash R., Cilenti L., DuBois G., Lazebnik Y., Zervos A.S., Fernandes-Alnemri T., Alnemri E.S. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. Journal of Biological Chemistry. 277:2002;432-438
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 432-438
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.3
Wassell, R.4
Mukattash, R.5
Cilenti, L.6
Dubois, G.7
Lazebnik, Y.8
Zervos, A.S.9
Fernandes-Alnemri, T.10
Alnemri, E.S.11
-
37
-
-
0031582671
-
CED-4 is a stranger no more
-
Hengartner M.O. CED-4 is a stranger no more. Nature. 388:1997;714-715
-
(1997)
Nature
, vol.388
, pp. 714-715
-
-
Hengartner, M.O.1
-
40
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-kB activation
-
Hsu H., Xiong J., Goeddel D.V. The TNF receptor 1-associated protein TRADD signals cell death and NF-kB activation. Cell. 81:1995;495-504
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
41
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
Hsu H., Shu H.-B., Pan M.-G., Goeddel D.V. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 84:1996;299-308
-
(1996)
Cell
, vol.84
, pp. 299-308
-
-
Hsu, H.1
Shu, H.-B.2
Pan, M.-G.3
Goeddel, D.V.4
-
42
-
-
0001003612
-
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members
-
Hsu S.Y., Kaipia A., McGee E., Lomeli M., Hsueh A.J.W. Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Proceedings of the National Academy of Sciences of the United States of America. 94:1997;12401-12406
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, pp. 12401-12406
-
-
Hsu, S.Y.1
Kaipia, A.2
McGee, E.3
Lomeli, M.4
Hsueh, A.J.W.5
-
43
-
-
0030854775
-
Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death
-
Imaizumi K., Tsuda M., Imai Y., Wanaka A., Takagi T., Tohyama M. Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death. Journal of Biological Chemistry. 272:1997;18842-18848
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 18842-18848
-
-
Imaizumi, K.1
Tsuda, M.2
Imai, Y.3
Wanaka, A.4
Takagi, T.5
Tohyama, M.6
-
44
-
-
0034062136
-
Genes with homology to mammalian apoptosis regulators identified in zebrafish [letter]
-
Inohara N., Núñez G. Genes with homology to mammalian apoptosis regulators identified in zebrafish [letter]. Cell Death and Differentiation. 7:2000;509-510
-
(2000)
Cell Death and Differentiation
, vol.7
, pp. 509-510
-
-
Inohara, N.1
Núñez, G.2
-
46
-
-
0027281373
-
A novel protein domain required for apoptosis
-
Itoh N., Nagata S. A novel protein domain required for apoptosis. Journal of Biological Chemistry. 268:1993;10932-10937
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 10932-10937
-
-
Itoh, N.1
Nagata, S.2
-
47
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks T., Remington L., Williams B.O., Schmitt E.M., Halachmi S., Bronson R.T., Weinberg R.A. Tumor spectrum analysis in p53-mutant mice. Current Biology. 4:1994;1-7
-
(1994)
Current Biology
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
Weinberg, R.A.7
-
48
-
-
0030669560
-
Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice
-
Jäger R., Herzer U., Schenkel J., Weiher H. Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice. Oncogene. 15:1997;1787-1795
-
(1997)
Oncogene
, vol.15
, pp. 1787-1795
-
-
Jäger, R.1
Herzer, U.2
Schenkel, J.3
Weiher, H.4
-
49
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
-
Jeffers J.R., Parganas E., Lee Y., Yang C., Wang J., Brennan J., MacLean K.H., Han J., Chittenden T., Ihle J.N. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell. 4:2003;321-328
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
MacLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
-
50
-
-
0035377522
-
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension
-
Kataoka T., Holler N., Micheau O., Martinon F., Tinel A., Hofmann K., Tschopp J. Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension. Journal of Biological Chemistry. 276:2001;19548-19554
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 19548-19554
-
-
Kataoka, T.1
Holler, N.2
Micheau, O.3
Martinon, F.4
Tinel, A.5
Hofmann, K.6
Tschopp, J.7
-
51
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. British Journal of Cancer. 26:1972;239-257
-
(1972)
British Journal of Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
52
-
-
0028904163
-
Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
-
Kiefer M.C., Brauer M.J., Powers V.C., Wu J.J., Umansky S.R., Tomei L.D., Barr P.J. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature. 374:1995;736-739
-
(1995)
Nature
, vol.374
, pp. 736-739
-
-
Kiefer, M.C.1
Brauer, M.J.2
Powers, V.C.3
Wu, J.J.4
Umansky, S.R.5
Tomei, L.D.6
Barr, P.J.7
-
53
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity. 12:2000;611-620
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
54
-
-
0035910748
-
BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor a chimeric protein (PMLRARa) to block neutrophil differentiation and initiate acute leukemia
-
Kogan S.C., Brown D.E., Shultz D.B., Truong B.T., Lallemand-Breitenbach V., Guillemin M.C., Lagasse E., Weissman I.L., Bishop J.M. BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor a chimeric protein (PMLRARa) to block neutrophil differentiation and initiate acute leukemia. Journal of Experimental Medicine. 193:2001;531-543
-
(2001)
Journal of Experimental Medicine
, vol.193
, pp. 531-543
-
-
Kogan, S.C.1
Brown, D.E.2
Shultz, D.B.3
Truong, B.T.4
Lallemand-Breitenbach, V.5
Guillemin, M.C.6
Lagasse, E.7
Weissman, I.L.8
Bishop, J.M.9
-
55
-
-
0027480450
-
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to bcl-2
-
Kozopas K.M., Yang T., Buchan H.L., Zhou P., Craig R.W. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to bcl-2. Proceedings of the National Academy of Sciences of the United States of America. 90:1993;3516-3520
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, pp. 3516-3520
-
-
Kozopas, K.M.1
Yang, T.2
Buchan, H.L.3
Zhou, P.4
Craig, R.W.5
-
56
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A., Bassik M., Walensky L., Sorcinelli M., Weiler S., Korsmeyer S. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell. 2:2002;183
-
(2002)
Cancer Cell
, vol.2
, pp. 183
-
-
Letai, A.1
Bassik, M.2
Walensky, L.3
Sorcinelli, M.4
Weiler, S.5
Korsmeyer, S.6
-
57
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H., Zhu H., Xu C.-J., Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94:1998;491-501
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.-J.3
Yuan, J.4
-
58
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li L.Y., Luo X., Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature. 412:2001;95-99
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
59
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
-
Lindsten T., Ross A.J., King A., Zong W., Rathmell J.C., Shiels H.A., Ulrich E., Waymire K.G., Mahar P., Frauwirth K., et al. The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Molecular Cell. 6:2000;1389-1399
-
(2000)
Molecular Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
-
60
-
-
0346880501
-
The inhibitors of apoptosis: There is more to life than Bcl2
-
Liston P., Fong W.G., Korneluk R.G. The inhibitors of apoptosis: there is more to life than Bcl2. Oncogene. 22:2003;8568-8580
-
(2003)
Oncogene
, vol.22
, pp. 8568-8580
-
-
Liston, P.1
Fong, W.G.2
Korneluk, R.G.3
-
61
-
-
0346455759
-
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
-
Liu G., Parant J.M., Lang G., Chau P., Chavez-Reyes A., El-Naggar A.K., Multani A., Chang S., Lozano G. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nature Genetics. 36:2004;63-68
-
(2004)
Nature Genetics
, vol.36
, pp. 63-68
-
-
Liu, G.1
Parant, J.M.2
Lang, G.3
Chau, P.4
Chavez-Reyes, A.5
El-Naggar, A.K.6
Multani, A.7
Chang, S.8
Lozano, G.9
-
62
-
-
0033010612
-
Apoptosis inducing factor (AIF): A phylogenetically old, caspase-independent effector of cell death [In Process Citation]
-
Lorenzo H.K., Susin S.A., Penninger J., Kroemer G. Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death [In Process Citation]. Cell Death and Differentiation. 6:1999;516-524
-
(1999)
Cell Death and Differentiation
, vol.6
, pp. 516-524
-
-
Lorenzo, H.K.1
Susin, S.A.2
Penninger, J.3
Kroemer, G.4
-
63
-
-
0032555716
-
Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X., Budlhardjo I., Zou H., Slaughter C., Wang X. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 94:1998;481-490
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budlhardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
64
-
-
1042266548
-
Modulation of mammalian life span by the short isoform of p53
-
Maier B., Gluba W., Bernier B., Turner T., Mohammad K., Guise T., Sutherland A., Thorner M., Scrable H. Modulation of mammalian life span by the short isoform of p53. Genes and Development. 18:2004;306-319
-
(2004)
Genes and Development
, vol.18
, pp. 306-319
-
-
Maier, B.1
Gluba, W.2
Bernier, B.3
Turner, T.4
Mohammad, K.5
Guise, T.6
Sutherland, A.7
Thorner, M.8
Scrable, H.9
-
65
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden V.S., O'Connor L., O'Reilly L.A., Silke J., Metcalf D., Ekert P.G., Huang D.C., Cecconi F., Kuida K., Tomaselli K.J. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 419:2002;634-637
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
-
66
-
-
0037016707
-
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
-
Martins L.M., Iaccarino I., Tenev T., Gschmeissner S., Totty N.F., Lemoine N.R., Savopoulos J., Gray C.W., Creasy C.L., Dingwall C., Downward J. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. Journal of Biological Chemistry. 277:2002;439-444
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 439-444
-
-
Martins, L.M.1
Iaccarino, I.2
Tenev, T.3
Gschmeissner, S.4
Totty, N.F.5
Lemoine, N.R.6
Savopoulos, J.7
Gray, C.W.8
Creasy, C.L.9
Dingwall, C.10
Downward, J.11
-
67
-
-
0026053958
-
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
-
McDonnell T.J., Korsmeyer S.J. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature. 349:1991;254-256
-
(1991)
Nature
, vol.349
, pp. 254-256
-
-
McDonnell, T.J.1
Korsmeyer, S.J.2
-
68
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
Mihara M., Erster S., Zaika A., Petrenko O., Chittenden T., Pancoska P., Moll U.M. p53 has a direct apoptogenic role at the mitochondria. Molecular Cell. 11:2003;577-590
-
(2003)
Molecular Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
69
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
70
-
-
0036119568
-
A detailed transcriptional map of the chromosome 12p12 tumour suppressor locus
-
Montpetit A., Boily G., Sinnett D. A detailed transcriptional map of the chromosome 12p12 tumour suppressor locus. European Journal of Human Genetics. 10:2002;62-71
-
(2002)
European Journal of Human Genetics
, vol.10
, pp. 62-71
-
-
Montpetit, A.1
Boily, G.2
Sinnett, D.3
-
72
-
-
0034977277
-
Apaf-1 is a transcriptional target for E2F and p53
-
Moroni M.C., Hickman E.S., Denchi E.L., Caprara G., Colli E., Cecconi F., Müller H., Helin K. Apaf-1 is a transcriptional target for E2F and p53. Nature Cell Biology. 3:2001;552-558
-
(2001)
Nature Cell Biology
, vol.3
, pp. 552-558
-
-
Moroni, M.C.1
Hickman, E.S.2
Denchi, E.L.3
Caprara, G.4
Colli, E.5
Cecconi, F.6
Müller, H.7
Helin, K.8
-
73
-
-
15844412409
-
FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex
-
Muzio M., Chinnaiyan A.M., Kischkel F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R. FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex. Cell. 85:1996;817-827
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
74
-
-
0029840585
-
Fas ligand and immune evasion
-
Nagata S. Fas ligand and immune evasion. Nature Medicine. 2:1996;1306-1307
-
(1996)
Nature Medicine
, vol.2
, pp. 1306-1307
-
-
Nagata, S.1
-
75
-
-
0028927607
-
The Fas death factor
-
Nagata S., Golstein P. The Fas death factor. Science. 267:1995;1449-1456
-
(1995)
Science
, vol.267
, pp. 1449-1456
-
-
Nagata, S.1
Golstein, P.2
-
76
-
-
0029833679
-
The rise and fall of apoptosis during multistage tumorigenesis: Down-modulation contributes to tumor progression from angiogenic progenitors
-
Naik P., Karrim J., Hanahan D. The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors. Genes and Development. 10:1996;2105-2116
-
(1996)
Genes and Development
, vol.10
, pp. 2105-2116
-
-
Naik, P.1
Karrim, J.2
Hanahan, D.3
-
77
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Molecular Cell. 7:2001;683-694
-
(2001)
Molecular Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
78
-
-
0032472916
-
A dominant interfering mutant of FADD/Mort1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Newton K., Harris A.W., Bath M.L., Smith K.G.C., Strasser A. A dominant interfering mutant of FADD/Mort1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO Journal. 17:1998;706-718
-
(1998)
EMBO Journal
, vol.17
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.C.4
Strasser, A.5
-
79
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death and Differentiation. 6:1999;1028-1042
-
(1999)
Cell Death and Differentiation
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
80
-
-
0037097701
-
Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis
-
Nieborowska-Skorska M., Hoser G., Kossev P., Wasik M.A., Skorski T. Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis. Blood. 99:2002;4531-4539
-
(2002)
Blood
, vol.99
, pp. 4531-4539
-
-
Nieborowska-Skorska, M.1
Hoser, G.2
Kossev, P.3
Wasik, M.A.4
Skorski, T.5
-
81
-
-
0032518787
-
Bim: A novel member of the Bcl-2 family that promotes apoptosis
-
O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C.S. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO Journal. 17:1998;384-395
-
(1998)
EMBO Journal
, vol.17
, pp. 384-395
-
-
O'Connor, L.1
Strasser, A.2
O'Reilly, L.A.3
Hausmann, G.4
Adams, J.M.5
Cory, S.6
Huang, D.C.S.7
-
82
-
-
0034640281
-
Noxa, a BH3-only member of the bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., Yamashita T., Tokino T., Taniguchi T., Tanaka N. Noxa, a BH3-only member of the bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 288:2000;1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
83
-
-
0034664733
-
P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda K., Arakawa H., Tanaka T., Matsuda K., Tanikawa C., Mori T., Nishimori H., Tamai K., Tokino T., Nakamura Y., Taya Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell. 102:2000;849-862
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
84
-
-
0028149786
-
Checkpoints of dueling dimers foil death wishes
-
Oltvai Z.N., Korsmeyer S.J. Checkpoints of dueling dimers foil death wishes. Cell. 79:1994;189-192
-
(1994)
Cell
, vol.79
, pp. 189-192
-
-
Oltvai, Z.N.1
Korsmeyer, S.J.2
-
85
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog. Bax, that accelerates programmed cell death
-
Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog. Bax, that accelerates programmed cell death. Cell. 74:1993;609-619
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
87
-
-
0033559492
-
Soluble Fas ligand is chemotactic for human neutrophilic polymorphonuclear leukocytes
-
Ottonello L., Tortolina G., Amelotti M., Dallegri F. Soluble Fas ligand is chemotactic for human neutrophilic polymorphonuclear leukocytes. Journal of Immunology. 162:1999;3601-3606
-
(1999)
Journal of Immunology
, vol.162
, pp. 3601-3606
-
-
Ottonello, L.1
Tortolina, G.2
Amelotti, M.3
Dallegri, F.4
-
88
-
-
0032529166
-
L by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies
-
L by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies. Genes and Development. 12:1998;2475-2487
-
(1998)
Genes and Development
, vol.12
, pp. 2475-2487
-
-
Packham, G.1
White, E.L.2
Eischen, C.M.3
Yang, H.4
Parganas, E.5
Ihle, J.N.6
Grillot, D.A.M.7
Zambetti, G.P.8
Nuñez, G.9
Cleveland, J.L.10
-
90
-
-
0037013147
-
Suppression of Myc-induced apoptosis in b cells exposes multiple oncogenic properties of myc and triggers carcinogenic progression
-
Pelengaris S., Khan M., Evan G.I. Suppression of Myc-induced apoptosis in b cells exposes multiple oncogenic properties of myc and triggers carcinogenic progression. Cell. 109:2002;321-334
-
(2002)
Cell
, vol.109
, pp. 321-334
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.I.3
-
91
-
-
0031985413
-
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
-
Peschon J.J., Torrance D.S., Stocking K.L., Glaccum M.B., Otten C., Willis C.R., Charrier K., Morrissey P.J., Ware C.B., Mohler K.M. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. Journal of Immunology. 160:1998;943-952
-
(1998)
Journal of Immunology
, vol.160
, pp. 943-952
-
-
Peschon, J.J.1
Torrance, D.S.2
Stocking, K.L.3
Glaccum, M.B.4
Otten, C.5
Willis, C.R.6
Charrier, K.7
Morrissey, P.J.8
Ware, C.B.9
Mohler, K.M.10
-
93
-
-
0033104996
-
The pro-apoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
Puthalakath H., Huang D.C.S., O'Reilly L.A., King S.M., Strasser A. The pro-apoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Molecular Cell. 3:1999;287-296
-
(1999)
Molecular Cell
, vol.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.S.2
O'Reilly, L.A.3
King, S.M.4
Strasser, A.5
-
94
-
-
0035823238
-
Bmf: A pro-apoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
Puthalakath H., Villunger A., O'Reilly L.A., Beaumont J.G., Coultas L., Cheney R.E., Huang D.C.S., Strasser A. Bmf: a pro-apoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science. 293:2001;1829-1832
-
(2001)
Science
, vol.293
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
Huang, D.C.S.7
Strasser, A.8
-
95
-
-
0031018674
-
Somatic frameshift mutations in the bax gene in colon cancers of the microsatellite mutator phenotype
-
Rampino N., Yamamoto H., Ionov Y., Li Y., Sawai H., Reed J.C., Perucho M. Somatic frameshift mutations in the bax gene in colon cancers of the microsatellite mutator phenotype. Science. 275:1997;967-969
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Ionov, Y.3
Li, Y.4
Sawai, H.5
Reed, J.C.6
Perucho, M.7
-
96
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena L., Lemmers B., Hakem A., Matysiak-Zablocki E., Murakami K., Au P.Y., Berry D.M., Tamblyn L., Shehabeldin A., Migon E., et al. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes and Dev. 17:2003;883-895
-
(2003)
Genes and Dev
, vol.17
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
Berry, D.M.7
Tamblyn, L.8
Shehabeldin, A.9
Migon, E.10
-
98
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
Sax J.K., Fei P., Murphy M.E., Bernhard E., Korsmeyer S.J., El-Deiry W.S. BID regulation by p53 contributes to chemosensitivity. Nature Cell Biology. 4:2002;842-849
-
(2002)
Nature Cell Biology
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
99
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C., Fulda S., Srinivasan A., Friesen C., Li F., Tomaselli K.J., Debatin K.-M., Krammer P.H., Peter M.E. Two CD95 (APO-1/Fas) signaling pathways. EMBO Journal. 17:1998;1675-1687
-
(1998)
EMBO Journal
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.-M.7
Krammer, P.H.8
Peter, M.E.9
-
100
-
-
0036527761
-
Dissecting p53 tumor suppressor functions in vivo
-
Schmitt C.A., Fridman J.S., Yang M., Baranov E., Hoffman R.M., Lowe S.W. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell. 1:2002;289-298
-
(2002)
Cancer Cell
, vol.1
, pp. 289-298
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Baranov, E.4
Hoffman, R.M.5
Lowe, S.W.6
-
101
-
-
0032550366
-
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
-
Schneider P., Holler N., Bodmer J.L., Hahne M., Frei K., Fontana A., Tschopp J. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. Journal of Experimental Medicine. 187:1998;1205-1213
-
(1998)
Journal of Experimental Medicine
, vol.187
, pp. 1205-1213
-
-
Schneider, P.1
Holler, N.2
Bodmer, J.L.3
Hahne, M.4
Frei, K.5
Fontana, A.6
Tschopp, J.7
-
102
-
-
0035975986
-
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
-
Schumacher B., Hofmann K., Boulton S., Gartner A. The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Current Biology. 11:2001;1722-1727
-
(2001)
Current Biology
, vol.11
, pp. 1722-1727
-
-
Schumacher, B.1
Hofmann, K.2
Boulton, S.3
Gartner, A.4
-
103
-
-
0032209454
-
Chemotactic activity of soluble Fas ligand against phagocytes
-
Seino K., Iwabuchi K., Kayagaki N., Miyata R., Nagaoka I., Matsuzawa A., Fukao K., Yagita H., Okumura K. Chemotactic activity of soluble Fas ligand against phagocytes. Journal of Immunology. 161:1998;4484-4488
-
(1998)
Journal of Immunology
, vol.161
, pp. 4484-4488
-
-
Seino, K.1
Iwabuchi, K.2
Kayagaki, N.3
Miyata, R.4
Nagaoka, I.5
Matsuzawa, A.6
Fukao, K.7
Yagita, H.8
Okumura, K.9
-
104
-
-
0033577766
-
Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: Reduction in protective apoptotic response at the preneoplastic stage
-
Shibata M.A., Liu M.L., Knudson M.C., Shibata E., Yoshidome K., Bandey T., Korsmeyer S.J., Green J.E. Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage. EMBO Journal. 18:1999;2692-2701
-
(1999)
EMBO Journal
, vol.18
, pp. 2692-2701
-
-
Shibata, M.A.1
Liu, M.L.2
Knudson, M.C.3
Shibata, E.4
Yoshidome, K.5
Bandey, T.6
Korsmeyer, S.J.7
Green, J.E.8
-
105
-
-
0141818136
-
Integral role of Noxa in p53-mediated apoptotic response
-
Shibue T., Takeda K., Oda E., Tanaka H., Murasawa H., Takaoka A., Morishita Y., Akira S., Taniguchi T., Tanaka N. Integral role of Noxa in p53-mediated apoptotic response. Genes and Development. 17:2003;2233-2238
-
(2003)
Genes and Development
, vol.17
, pp. 2233-2238
-
-
Shibue, T.1
Takeda, K.2
Oda, E.3
Tanaka, H.4
Murasawa, H.5
Takaoka, A.6
Morishita, Y.7
Akira, S.8
Taniguchi, T.9
Tanaka, N.10
-
106
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas M.S., Alarcón R.M., Yoshida H., Giaccia A.J., Hakem R., Mak T.W., Lowe S.W. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science. 284:1999;156-159
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcón, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
107
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick M.R., Weigand M.A., Rieser E., Rauch C.T., Juo P., Blenis J., Krammer P.H., Walczak H. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity. 12:2000;599-609
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
Krammer, P.H.7
Walczak, H.8
-
108
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
Stambolic V., MacPherson D., Sas D., Lin Y., Snow B., Jang Y., Benchimol S., Mak T.W. Regulation of PTEN transcription by p53. Molecular Cell. 8:2001;317-325
-
(2001)
Molecular Cell
, vol.8
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
Lin, Y.4
Snow, B.5
Jang, Y.6
Benchimol, S.7
Mak, T.W.8
-
110
-
-
0025251664
-
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2
-
Strasser A., Harris A.W., Bath M.L., Cory S. Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature. 348:1990;331-333
-
(1990)
Nature
, vol.348
, pp. 331-333
-
-
Strasser, A.1
Harris, A.W.2
Bath, M.L.3
Cory, S.4
-
111
-
-
0025939204
-
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
-
Strasser A., Whittingham S., Vaux D.L., Bath M.L., Adams J.M., Cory S., Harris A.W. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proceedings of the National Academy of Sciences of the USA. 88:1991;8661-8665
-
(1991)
Proceedings of the National Academy of Sciences of the USA
, vol.88
, pp. 8661-8665
-
-
Strasser, A.1
Whittingham, S.2
Vaux, D.L.3
Bath, M.L.4
Adams, J.M.5
Cory, S.6
Harris, A.W.7
-
113
-
-
0027461627
-
Em-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells
-
Strasser A., Harris A.W., Cory S. Em-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells. Oncogene. 8:1993;1-9
-
(1993)
Oncogene
, vol.8
, pp. 1-9
-
-
Strasser, A.1
Harris, A.W.2
Cory, S.3
-
114
-
-
0028072523
-
DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
-
Strasser A., Harris A.W., Jacks T., Cory S. DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell. 79:1994;329-339
-
(1994)
Cell
, vol.79
, pp. 329-339
-
-
Strasser, A.1
Harris, A.W.2
Jacks, T.3
Cory, S.4
-
115
-
-
0029609086
-
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
-
Strasser A., Harris A.W., Huang D.C.S., Krammer P.H., Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO Journal. 14:1995;6136-6147
-
(1995)
EMBO Journal
, vol.14
, pp. 6136-6147
-
-
Strasser, A.1
Harris, A.W.2
Huang, D.C.S.3
Krammer, P.H.4
Cory, S.5
-
117
-
-
0036154895
-
Aging alters the apoptotic response to genotoxic stress
-
Suh Y., Lee K.A., Kim W.H., Han B.G., Vijg J., Park S.C. Aging alters the apoptotic response to genotoxic stress. Nature Medicine. 8:2002;3-4
-
(2002)
Nature Medicine
, vol.8
, pp. 3-4
-
-
Suh, Y.1
Lee, K.A.2
Kim, W.H.3
Han, B.G.4
Vijg, J.5
Park, S.C.6
-
118
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M., Youle R.J., Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell. 103:2000;645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
119
-
-
0034785591
-
A serine protease HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y., Imai Y., Nakayama H., Takahashi K., Takio K., Takahashi R. A serine protease HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Molecular Cell. 8:2001;613-621
-
(2001)
Molecular Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
121
-
-
0027275490
-
A novel domain within the 55 kd TNF receptor signals cell death
-
Tartaglia L.A., Ayres T.M., Wong G.H.W., Goeddel D.V. A novel domain within the 55 kd TNF receptor signals cell death. Cell. 74:1993;845-853
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.W.3
Goeddel, D.V.4
-
122
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
123
-
-
0032126364
-
Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia
-
Traver D., Akashi K., Weissman I.L., Lagasse E. Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia. Immunity. 9:1998;47-57
-
(1998)
Immunity
, vol.9
, pp. 47-57
-
-
Traver, D.1
Akashi, K.2
Weissman, I.L.3
Lagasse, E.4
-
124
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
-
Tsujimoto Y., Finger L.R., Yunis J., Nowell P.C., Croce C.M. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science. 226:1984;1097-1099
-
(1984)
Science
, vol.226
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
Nowell, P.C.4
Croce, C.M.5
-
125
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
Tyner S.D., Venkatachalam S., Choi J., Jones S., Ghebranious N., Igelmann H., Lu X., Soron G., Cooper B., Brayton C., et al. p53 mutant mice that display early ageing-associated phenotypes. Nature. 415:2002;45-53
-
(2002)
Nature
, vol.415
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
-
126
-
-
18244386261
-
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
-
van Loo G., van Gurp M., Depuydt B., Srinivasula S.M., Rodriguez I., Alnemri E.S., Gevaert K., Vandekerckhove J., Declercq W., Vandenabeele P. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. Cell Death and Differentiation. 9:2002;20-26
-
(2002)
Cell Death and Differentiation
, vol.9
, pp. 20-26
-
-
Van Loo, G.1
Van Gurp, M.2
Depuydt, B.3
Srinivasula, S.M.4
Rodriguez, I.5
Alnemri, E.S.6
Gevaert, K.7
Vandekerckhove, J.8
Declercq, W.9
Vandenabeele, P.10
-
127
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux D.L., Cory S., Adams J.M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature. 335:1988;440-442
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
128
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing inhibitor of apoptosis (IAP) proteins
-
Verhagen A.M., Ekert P.G., Pakusch M., Silke J., Connolly L.M., Reid G.E., Moritz R.L., Simpson R.J., Vaux D.L. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing inhibitor of apoptosis (IAP) proteins. Cell. 102:2000;43-53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
129
-
-
0037016686
-
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
-
Verhagen A.M., Silke J., Ekert P.G., Pakusch M., Kaufmann H., Connolly L.M., Day C.L., Tikoo A., Burke R., Wrobel C. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. Journal of Biological Chemistry. 277:2002;445-454
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 445-454
-
-
Verhagen, A.M.1
Silke, J.2
Ekert, P.G.3
Pakusch, M.4
Kaufmann, H.5
Connolly, L.M.6
Day, C.L.7
Tikoo, A.8
Burke, R.9
Wrobel, C.10
-
130
-
-
0034605032
-
Bcl-2, G-CSF and p38 MAPK: Regulators of distinct cell death and survival pathways in granulocytes Fas ligand
-
Villunger A., O'Reilly L.A., Holler N., Adams J.M., Strasser A. Bcl-2, G-CSF and p38 MAPK: regulators of distinct cell death and survival pathways in granulocytes Fas ligand. Journal of Experimental Medicine. 192:2000;647-657
-
(2000)
Journal of Experimental Medicine
, vol.192
, pp. 647-657
-
-
Villunger, A.1
O'Reilly, L.A.2
Holler, N.3
Adams, J.M.4
Strasser, A.5
-
131
-
-
0242410719
-
P53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A., Michalak E.M., Coultas L., Mullauer F., Bock G., Ausserlechner M.J., Adams J.M., Strasser A. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science. 302:2003;1036-1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
132
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden K.H., Lu X. Live or let die: the cell's response to p53. Nature Reviews. Cancer. 2:2002;594-604
-
(2002)
Nature Reviews. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
133
-
-
0036360019
-
The enemy within: Keeping self-reactive T cells at bay in the periphery
-
Walker L.S., Abbas A.K. The enemy within: keeping self-reactive T cells at bay in the periphery. Nature Reviews. Immunology. 2:2002;11-19
-
(2002)
Nature Reviews. Immunology
, vol.2
, pp. 11-19
-
-
Walker, L.S.1
Abbas, A.K.2
-
135
-
-
0029807585
-
BID: A novel BH3 domain-only death agonist
-
Wang K., Yin X.-M., Chao D.T., Milliman C.L., Korsmeyer S.J. BID: a novel BH3 domain-only death agonist. Genes and Development. 10:1996;2859-2869
-
(1996)
Genes and Development
, vol.10
, pp. 2859-2869
-
-
Wang, K.1
Yin, X.-M.2
Chao, D.T.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
137
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., Roth K.A., MacGregor G.R., Thompson C.B., Korsmeyer S.J. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science. 292:2001;727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
138
-
-
0142092617
-
Caspase-3 regulates cell cycle in B cells: A consequence of substrate specificity
-
Woo M., Hakem R., Furlonger C., Hakem A., Duncan G.S., Sasaki T., Bouchard D., Lu L., Wu G.E., Paige C.J., Mak T.W. Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity. Nature Immunology. 4:2003;1016-1022
-
(2003)
Nature Immunology
, vol.4
, pp. 1016-1022
-
-
Woo, M.1
Hakem, R.2
Furlonger, C.3
Hakem, A.4
Duncan, G.S.5
Sasaki, T.6
Bouchard, D.7
Lu, L.8
Wu, G.E.9
Paige, C.J.10
Mak, T.W.11
-
139
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu G.S., Burns T.F., McDonald E.R. III, Jiang W., Meng R., Krantz I.D., Kao G., Gan D.-D., Zhou J.-Y., Muschel R., et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nature Genetics. 17:1997;141-143
-
(1997)
Nature Genetics
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
Mcdonald III, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.-D.8
Zhou, J.-Y.9
Muschel, R.10
-
141
-
-
0028809209
-
L and Bcl-2, displaces Bax and promotes cell death
-
L and Bcl-2, displaces Bax and promotes cell death. Cell. 80:1995;285-291
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
142
-
-
0035851181
-
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
-
Yannone S.M., Roy S., Chan D.W., Murphy M.B., Huang S., Campisi J., Chen D.J. Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase. Journal of Biological Chemistry. 276:2001;38242-38248
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 38242-38248
-
-
Yannone, S.M.1
Roy, S.2
Chan, D.W.3
Murphy, M.B.4
Huang, S.5
Campisi, J.6
Chen, D.J.7
-
143
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
Yin C.Y., Knudson C.M., Korsmeyer S.J., Van Dyke T. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature. 385:1997;637-640
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.Y.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van Dyke, T.4
-
144
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin X.-M., Wang K., Gross A., Zhao Y., Zinkel S., Klocke B., Roth K.A., Korsmeyer S.J. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature. 400:1999;886-891
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.-M.1
Wang, K.2
Gross, A.3
Zhao, Y.4
Zinkel, S.5
Klocke, B.6
Roth, K.A.7
Korsmeyer, S.J.8
-
145
-
-
0036307307
-
P53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products
-
Yin Y., Stephen C.W., Luciani M.G., Fahraeus R. p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products. Nature Cell Biology. 4:2002;462-467
-
(2002)
Nature Cell Biology
, vol.4
, pp. 462-467
-
-
Yin, Y.1
Stephen, C.W.2
Luciani, M.G.3
Fahraeus, R.4
-
146
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J., Zhang L., Hwang P.M., Kinzler K.W., Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Molecular Cell. 7:2001;673-682
-
(2001)
Molecular Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
147
-
-
0037452759
-
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
-
Yu J., Wang Z., Kinzler K.W., Vogelstein B., Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100:2003;1931-1936
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 1931-1936
-
-
Yu, J.1
Wang, Z.2
Kinzler, K.W.3
Vogelstein, B.4
Zhang, L.5
-
149
-
-
0032546387
-
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Zhang J., Cado D., Chen A., Kabra N.H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature. 392:1998;296-300
-
(1998)
Nature
, vol.392
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
150
-
-
0035877981
-
MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes
-
Zhou P., Levy N.B., Xie H., Qian L., Lee C.Y., Gascoyne R.D., Craig R.W. MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes. Blood. 97:2001;3902-3909
-
(2001)
Blood
, vol.97
, pp. 3902-3909
-
-
Zhou, P.1
Levy, N.B.2
Xie, H.3
Qian, L.4
Lee, C.Y.5
Gascoyne, R.D.6
Craig, R.W.7
-
151
-
-
0037439151
-
Proapoptotic BID is required for myeloid homeostasis and tumor suppression
-
Zinkel S.S., Ong C.C., Ferguson D.O., Iwasaki H., Akashi K., Bronson R.T., Kutok J.L., Alt F.W., Korsmeyer S.J. Proapoptotic BID is required for myeloid homeostasis and tumor suppression. Genes and Development. 17:2003;229-239
-
(2003)
Genes and Development
, vol.17
, pp. 229-239
-
-
Zinkel, S.S.1
Ong, C.C.2
Ferguson, D.O.3
Iwasaki, H.4
Akashi, K.5
Bronson, R.T.6
Kutok, J.L.7
Alt, F.W.8
Korsmeyer, S.J.9
-
152
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong W.X., Lindsten T., Ross A.J., MacGregor G.R., Thompson C.B. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes and Development. 15:2001;1481-1486
-
(2001)
Genes and Development
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
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