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Volumn 10, Issue 17, 1996, Pages 2105-2116

The rise and fall of apoptosis during multistage tumorigenesis: Down- modulation contributes to tumor progression from angiogenic progenitors

Author keywords

Apoptosis; bcl x(L); p53

Indexed keywords

PROTEIN P53;

EID: 0029833679     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.17.2105     Document Type: Article
Times cited : (197)

References (60)
  • 2
    • 0023949396 scopus 로고
    • Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons
    • Alpert, S., D. Hanahan, and G. Teitelman. 1988. Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell 53: 295-308.
    • (1988) Cell , vol.53 , pp. 295-308
    • Alpert, S.1    Hanahan, D.2    Teitelman, G.3
  • 3
    • 0021934042 scopus 로고
    • Cloning the chromosomal breakpoint of t(14;18) human lymphomas clustering around JH on chromosome 14 and near a transcriptional unit on 18
    • Bakhshi, A., J.P. Jensen, P. Goldman, J.J. Wright, C.W. McBride, A.L. Epstein, and S.J. Korsmeyer. 1985. Cloning the chromosomal breakpoint of t(14;18) human lymphomas clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 41: 899-906.
    • (1985) Cell , vol.41 , pp. 899-906
    • Bakhshi, A.1    Jensen, J.P.2    Goldman, P.3    Wright, J.J.4    McBride, C.W.5    Epstein, A.L.6    Korsmeyer, S.J.7
  • 6
    • 0027436691 scopus 로고
    • Cell proliferation, DNA repairp53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation
    • Berges, R.R., Y. Furuya, L. Remington, H.F. English, and T. Jacks. 1993. Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation. Proc. Natl. Acad. Sci. 90: 8910-8914.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 8910-8914
    • Berges, R.R.1    Furuya, Y.2    Remington, L.3    English, H.F.4    Jacks, T.5
  • 8
    • 0028356419 scopus 로고
    • A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis
    • Christofori, G., P. Naik, and D. Hanahan. 1994. A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 369: 414-418.
    • (1994) Nature , vol.369 , pp. 414-418
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 10
    • 0345055662 scopus 로고
    • Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18
    • Cleary, M.L. and J. Sklar. 1985. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18. Proc. Natl. Acad. Sci. 82: 7439-7443.
    • (1985) Proc. Natl. Acad. Sci. , vol.82 , pp. 7439-7443
    • Cleary, M.L.1    Sklar, J.2
  • 12
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron, K.M., O.V. Volpert, M.A. Tainsky, and N. Bouck. 1994. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265: 1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 13
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
    • Debbas, M. and E. White. 1993. Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes & Dev. 7: 546-554.
    • (1993) Genes & Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 15
    • 0023412375 scopus 로고
    • Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes
    • Efrat, S., S. Baekkeskov, D. Lane, and D. Hanahan. 1987. Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes. EMBO J. 6: 2699-2704.
    • (1987) EMBO J. , vol.6 , pp. 2699-2704
    • Efrat, S.1    Baekkeskov, S.2    Lane, D.3    Hanahan, D.4
  • 17
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • Folkman, J., K. Watson, D. Ingber, and D. Hanahan. 1989. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 339: 58-61.
    • (1989) Nature , vol.339 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 18
    • 0021888904 scopus 로고
    • Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/ simian virus 40 oncogenes
    • Hanahan, D. 1985. Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/ simian virus 40 oncogenes. Nature 315: 115-122.
    • (1985) Nature , vol.315 , pp. 115-122
    • Hanahan, D.1
  • 19
    • 0028263811 scopus 로고
    • C-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington, E.A., M.R. Bennett, A. Fanidi, and G.I. Evan. 1994. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13: 3286-3295.
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 20
    • 0028171968 scopus 로고
    • Mediation of c-Myc-induced apoptosis by p53
    • Hermeking, H. and D. Eick. 1994. Mediation of c-Myc-induced apoptosis by p53. Science 265: 2091-2093.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 21
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenberry, D., G. Nunez, C. Milliman, R.D. Schreiber, and S.J. Korsmeyer. 1990. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenberry, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 22
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren, L., M.S. O'Reilly, and J. Folkman. 1995. Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Med. 1: 149-153.
    • (1995) Nature Med. , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 23
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes, K.A., N. Ransom, D.S. Papermaster, J.G.H. Lasudry, D.M. Albert, and J.J. Windle. 1994. Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes & Dev. 8: 1300-1310.
    • (1994) Genes & Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.H.4    Albert, D.M.5    Windle, J.J.6
  • 26
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer, S.J. 1992. Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 80: 879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 27
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • Lacy, P.E. and M. Kostianovsky. 1967. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35-39.
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 28
    • 0027451668 scopus 로고
    • P53-Dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S.W., H.E. Ruley, T. Jacks, and D.E. Housman. 1993a. p53-Dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 29
    • 0027319521 scopus 로고
    • P53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., E.M. Schmitt, S.W. Smith, B.A. Osborne, and T. Jacks. 1993b. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 30
    • 0027218350 scopus 로고
    • Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53
    • Ludlow, J.W. 1993. Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB J. 7: 866-871.
    • (1993) FASEB J. , vol.7 , pp. 866-871
    • Ludlow, J.W.1
  • 31
    • 0026053958 scopus 로고
    • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
    • McDonnell, T.J. and S.J. Korsmeyer. 1991. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature 349: 254-256.
    • (1991) Nature , vol.349 , pp. 254-256
    • McDonnell, T.J.1    Korsmeyer, S.J.2
  • 32
    • 0027093255 scopus 로고
    • Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • McDonnell, T.J., P. Troncoso, S.M. Brisbay, C. Logothetis, L.W.K. Chung, J. Hsieh, S. Tu, and M.L. Campbell. 1992. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res. 52: 6940-6944.
    • (1992) Cancer Res. , vol.52 , pp. 6940-6944
    • McDonnell, T.J.1    Troncoso, P.2    Brisbay, S.M.3    Logothetis, C.4    Chung, L.W.K.5    Hsieh, J.6    Tu, S.7    Campbell, M.L.8
  • 34
    • 0027934570 scopus 로고
    • P53-Dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S.D., B.O. Williams, T. Jacks, and R.A. DePinho. 1994. p53-Dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    Depinho, R.A.4
  • 36
    • 0028674214 scopus 로고
    • Insulin-like growth factor II is focally up-regulated and functionally involved as a second signal for oncogene-induced tumorigenesis
    • Naik, P., G. Christofori, and D. Hanahan. 1994. Insulin-like growth factor II is focally up-regulated and functionally involved as a second signal for oncogene-induced tumorigenesis. Cold Spring Harbor Symp. Quant. Biol. 59: 459-470.
    • (1994) Cold Spring Harbor Symp. Quant. Biol. , vol.59 , pp. 459-470
    • Naik, P.1    Christofori, G.2    Hanahan, D.3
  • 37
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death
    • Oltvai, Z.N., C.L. Milliman, and S. Korsmeyer. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.3
  • 38
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim, R.W. 1991. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14: 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 39
    • 0024369203 scopus 로고
    • Insulin-like growth factor-II: A potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor
    • Osborne, C.K., E.B. Coronado, L.J. Kitten, C.I. Arteaga, S.A. Fuqua, and K. Ramaharma. 1989. Insulin-like growth factor-II: A potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol. Endocrinol. 3: 1701-1709.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1701-1709
    • Osborne, C.K.1    Coronado, E.B.2    Kitten, L.J.3    Arteaga, C.I.4    Fuqua, S.A.5    Ramaharma, K.6
  • 40
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function development
    • Pan, H. and A.E. Griep. 1994. Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function development. Genes & Dev. 8: 1285-1299.
    • (1994) Genes & Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 41
    • 0028818712 scopus 로고
    • Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma
    • Parangi, S., W. Dietrich, G. Christofori, E.S. Lander, and D. Hanahan. 1995. Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma. Cancer Res. 55: 6071-6076.
    • (1995) Cancer Res. , vol.55 , pp. 6071-6076
    • Parangi, S.1    Dietrich, W.2    Christofori, G.3    Lander, E.S.4    Hanahan, D.5
  • 43
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff, M. 1992. Social controls on cell survival and cell death. Nature 356: 397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.1
  • 44
    • 0028972728 scopus 로고
    • Bcl-XL protects cancer cells from p53-mediated apoptosis
    • Schott, A.F., I.J. Apel, G. Nunez, and M.F. Clarke. 1995. Bcl-XL protects cancer cells from p53-mediated apoptosis. Oncogene 11: 1389-1394.
    • (1995) Oncogene , vol.11 , pp. 1389-1394
    • Schott, A.F.1    Apel, I.J.2    Nunez, G.3    Clarke, M.F.4
  • 45
    • 0025251664 scopus 로고
    • Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2
    • Strasser, A., A.W. Harris, M.L. Bath, and S. Cory. 1990. Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature 348: 331-333.
    • (1990) Nature , vol.348 , pp. 331-333
    • Strasser, A.1    Harris, A.W.2    Bath, M.L.3    Cory, S.4
  • 46
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by bcl-2
    • Strasser, A., A.W. Harris, T. Jacks, and S. Cory. 1994. DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by bcl-2. Cell 79: 329-339.
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3    Cory, S.4
  • 47
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh, C.D. and J. Sprent. 1994. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372: 100-103.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 49
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama, S., T. Sato, S. Krajewski, K. Kochel, S. Irie, J.A. Millan, and J.C. Reed. 1995. Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity. Cell 80: 279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 50
    • 0023838995 scopus 로고
    • Proliferation, senescenceneoplastic progression of beta cells in hyperplasic pancreatic islets
    • Teitelman, G., S. Alpert, and D. Hanahan. 1988. Proliferation, senescence, and neoplastic progression of beta cells in hyperplasic pancreatic islets. Cell 52: 97-105.
    • (1988) Cell , vol.52 , pp. 97-105
    • Teitelman, G.1    Alpert, S.2    Hanahan, D.3
  • 51
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C.B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 52
    • 0022379447 scopus 로고
    • The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
    • Tsujimoto, Y., J. Gorham, J. Cossman, E. Jaffe, and C.M. Croce. 1985. The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229: 1390-1393.
    • (1985) Science , vol.229 , pp. 1390-1393
    • Tsujimoto, Y.1    Gorham, J.2    Cossman, J.3    Jaffe, E.4    Croce, C.M.5
  • 53
    • 0023786047 scopus 로고
    • Bcl-2 promotes the survival of hematopoietic cells and cooperates with c-myc to immortalize pre-B cells
    • Vaux, D.L., S. Cory, and T.M. Adams. 1988. Bcl-2 promotes the survival of hematopoietic cells and cooperates with c-myc to immortalize pre-B cells. Nature 335: 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, T.M.3
  • 56
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White, E. 1996. Life, death, and the pursuit of apoptosis. Genes & Dev. 10: 1-15.
    • (1996) Genes & Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 57
    • 0345570572 scopus 로고
    • Regulation of apoptosis by the transforming gene products of adenovirus
    • ed. E. Mihich and R.T. Schimke Plenum Press, New York, NY
    • White, E., L. Rao, S.K. Chiou, C.C. Tseng, P. Sabbatini, M. Gonzalez, and P. Verwaerde. 1994. Regulation of apoptosis by the transforming gene products of adenovirus. In Apoptosis (ed. E. Mihich and R.T. Schimke), pp. 47. Plenum Press, New York, NY.
    • (1994) Apoptosis , pp. 47
    • White, E.1    Rao, L.2    Chiou, S.K.3    Tseng, C.C.4    Sabbatini, P.5    Gonzalez, M.6    Verwaerde, P.7
  • 58
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A.H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 59
    • 0026038047 scopus 로고
    • The insulin-like growth factors, their receptorstheir binding proteins in human breast cancer
    • Yee, D., N. Rosen, R.E. Favoni, and K.J. Cullen. 1991. The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer. Cancer Treat. Res. 53: 93-106.
    • (1991) Cancer Treat. Res. , vol.53 , pp. 93-106
    • Yee, D.1    Rosen, N.2    Favoni, R.E.3    Cullen, K.J.4


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