-
1
-
-
0035853811
-
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
Antonsson, B., Montessuit, S., Sanchez, B., and Martinou, J.C. 2001. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J. Biol. Chem. 276: 11615-11623.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.C.4
-
2
-
-
0037089068
-
BH3-only proteins: Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
-
Bouillet, P. and Strasser, A. 2002. BH3-only proteins: Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J. Cell Sci. 115: 1567-1574.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1567-1574
-
-
Bouillet, P.1
Strasser, A.2
-
3
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke, A.R., Purdie, C.A., Harrison, D.J., Morris, R.G., Bird, C.C., Hooper, M.L., and Wyllie, A.H. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
4
-
-
18644376568
-
Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage
-
Deverman, B.E., Cook, B.L., Manson, S.R., Niederhoff, R.A., Langer, E.M., Rosova, I., Kulans, L.A., Fu, X., Weinberg, J.S., Heinecke, J.W., et al. 2002. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell 111: 51-62.
-
(2002)
Cell
, vol.111
, pp. 51-62
-
-
Deverman, B.E.1
Cook, B.L.2
Manson, S.R.3
Niederhoff, R.A.4
Langer, E.M.5
Rosova, I.6
Kulans, L.A.7
Fu, X.8
Weinberg, J.S.9
Heinecke, J.W.10
-
5
-
-
0036594890
-
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
-
Gartel, A.L. and Tyner, A.L. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1: 639-649.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 639-649
-
-
Gartel, A.L.1
Tyner, A.L.2
-
6
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping, I.S., Gross, A., Lavoie, J.N., Nguyen, M., Jemmerson, R., Roth, K., Korsmeyer, S.J., and Shore, G.C. 1998. Regulated targeting of BAX to mitochondria. J. Cell Biol. 143: 207-215.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
7
-
-
0030021996
-
Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
-
Hawkins, D.S., Demers, G.W., and Galloway, D.A. 1996. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res. 56: 892-898.
-
(1996)
Cancer Res.
, vol.56
, pp. 892-898
-
-
Hawkins, D.S.1
Demers, G.W.2
Galloway, D.A.3
-
8
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
Knudson, C.M., Tung, K.S., Tourtellotte, W.G., Brown, G.A., and Korsmeyer, S.J. 1995. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270: 96-99.
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.2
Tourtellotte, W.G.3
Brown, G.A.4
Korsmeyer, S.J.5
-
9
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko, L.J. and Prives, C. 1996. p53: Puzzle and paradigm. Genes & Dev. 10: 1054-1072.
-
(1996)
Genes & Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
10
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer, C., Kinzler, K.W., and Vogelstein, B. 1998. Genetic instabilities in human cancers. Nature 396: 643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
11
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe, S.W., Ruley, H.E., Jacks, T., and Housman, D.E. 1993a. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
12
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A., and Jacks, T. 1993b. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
13
-
-
0028323294
-
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells
-
Lowe, S.W., Jacks, T., Housman, D.E., and Ruley, H.E. 1994. Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc. Natl. Acad. Sci. 91: 2026-2030.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 2026-2030
-
-
Lowe, S.W.1
Jacks, T.2
Housman, D.E.3
Ruley, H.E.4
-
14
-
-
0030938089
-
Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
-
McCurrach, M.E., Connor, T.M., Knudson, C.M., Korsmeyer, S.J., and Lowe, S.W. 1997. Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. 94: 2345-2349.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 2345-2349
-
-
McCurrach, M.E.1
Connor, T.M.2
Knudson, C.M.3
Korsmeyer, S.J.4
Lowe, S.W.5
-
15
-
-
0028047723
-
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
-
Merritt, A.J., Porten, C.S., Kemp, C.J., Hickman, J.A., Balmain, A., Lane, D.P., and Hall, P.A. 1994. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 54: 614-617.
-
(1994)
Cancer Res.
, vol.54
, pp. 614-617
-
-
Merritt, A.J.1
Porten, C.S.2
Kemp, C.J.3
Hickman, J.A.4
Balmain, A.5
Lane, D.P.6
Hall, P.A.7
-
16
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano, K. and Vousden, K.H. 2001. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7: 683-694.
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
17
-
-
0034640281
-
Noxa: A BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. 2000. Noxa: A BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
18
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris, F., Fuks, Z., Kang, A., Capodieci, P., Juan, G., Ehleiter, D., Haimovitz-Friedman, A., Cordon-Cardo, C., and Kolesnick, R. 2001. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293: 293-297.
-
(2001)
Science
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
Capodieci, P.4
Juan, G.5
Ehleiter, D.6
Haimovitz-Friedman, A.7
Cordon-Cardo, C.8
Kolesnick, R.9
-
19
-
-
0034641963
-
Defying death after DNA damage
-
Rich, T., Allen, R.L., and Wyllie, A.H. 2000. Defying death after DNA damage. Nature 407: 777-783.
-
(2000)
Nature
, vol.407
, pp. 777-783
-
-
Rich, T.1
Allen, R.L.2
Wyllie, A.H.3
-
20
-
-
0036527761
-
Dissecting p53 tumor suppressor functions in vivo
-
Schmitt, C.A., Fridman, J.S., Yang, M., Baranov, E., Hoffman, R.M., and Lowe, S.W. 2002. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 1: 289-298.
-
(2002)
Cancer Cell
, vol.1
, pp. 289-298
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Baranov, E.4
Hoffman, R.M.5
Lowe, S.W.6
-
21
-
-
0026638951
-
Apoptosis: Biochemical events and relevance to cancer chemotherapy
-
Sen, S. and D'Incalci, M. 1992. Apoptosis: Biochemical events and relevance to cancer chemotherapy. FEBS Lett. 307: 122-127.
-
(1992)
FEBS Lett.
, vol.307
, pp. 122-127
-
-
Sen, S.1
D'Incalci, M.2
-
22
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda, K., Tanaka, T., Shi, W., Matsumoto, M., Minami, M., Kashiwamura, S., Nakanishi, K., Yoshida, N., Kishimoto, T., and Akira, S. 1996. Essential role of Stat6 in IL-4 signalling. Nature 380: 627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
23
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden, K.H. and Lu, X. 2002. Live or let die: The cell's response to p53. Nat. Rev. Cancer 2: 594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
24
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei, M.C., Zong, W.X., Cheng, E.H., Lindsten, T., Panoutsakopoulou, V., Ross, A.J., Roth, K.A., MacGregor, G.R., Thompson, C.B., and Korsmeyer, S.J. 2001. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
25
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu, J., Zhang, L., Hwang, P.M., Kinzler, K.W., and Vogelstein, B. 2001. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol. Cell 7: 673-682.
-
(2001)
Mol. Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
26
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
|