메뉴 건너뛰기




Volumn 17, Issue 18, 2003, Pages 2233-2238

Integral role of Noxa in p53-mediated apoptotic response

Author keywords

Apoptosis; Bcl 2 family; DNA damage; Oncogene; p53

Indexed keywords

PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NOXA; UNCLASSIFIED DRUG;

EID: 0141818136     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1103603     Document Type: Article
Times cited : (290)

References (26)
  • 1
    • 0035853811 scopus 로고    scopus 로고
    • Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
    • Antonsson, B., Montessuit, S., Sanchez, B., and Martinou, J.C. 2001. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J. Biol. Chem. 276: 11615-11623.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11615-11623
    • Antonsson, B.1    Montessuit, S.2    Sanchez, B.3    Martinou, J.C.4
  • 2
    • 0037089068 scopus 로고    scopus 로고
    • BH3-only proteins: Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
    • Bouillet, P. and Strasser, A. 2002. BH3-only proteins: Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J. Cell Sci. 115: 1567-1574.
    • (2002) J. Cell Sci. , vol.115 , pp. 1567-1574
    • Bouillet, P.1    Strasser, A.2
  • 5
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel, A.L. and Tyner, A.L. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1: 639-649.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 7
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins, D.S., Demers, G.W., and Galloway, D.A. 1996. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res. 56: 892-898.
    • (1996) Cancer Res. , vol.56 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 9
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko, L.J. and Prives, C. 1996. p53: Puzzle and paradigm. Genes & Dev. 10: 1054-1072.
    • (1996) Genes & Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 10
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer, C., Kinzler, K.W., and Vogelstein, B. 1998. Genetic instabilities in human cancers. Nature 396: 643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 11
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S.W., Ruley, H.E., Jacks, T., and Housman, D.E. 1993a. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 12
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A., and Jacks, T. 1993b. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 13
    • 0028323294 scopus 로고
    • Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells
    • Lowe, S.W., Jacks, T., Housman, D.E., and Ruley, H.E. 1994. Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc. Natl. Acad. Sci. 91: 2026-2030.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 2026-2030
    • Lowe, S.W.1    Jacks, T.2    Housman, D.E.3    Ruley, H.E.4
  • 14
    • 0030938089 scopus 로고    scopus 로고
    • Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
    • McCurrach, M.E., Connor, T.M., Knudson, C.M., Korsmeyer, S.J., and Lowe, S.W. 1997. Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. 94: 2345-2349.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 2345-2349
    • McCurrach, M.E.1    Connor, T.M.2    Knudson, C.M.3    Korsmeyer, S.J.4    Lowe, S.W.5
  • 15
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt, A.J., Porten, C.S., Kemp, C.J., Hickman, J.A., Balmain, A., Lane, D.P., and Hall, P.A. 1994. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 54: 614-617.
    • (1994) Cancer Res. , vol.54 , pp. 614-617
    • Merritt, A.J.1    Porten, C.S.2    Kemp, C.J.3    Hickman, J.A.4    Balmain, A.5    Lane, D.P.6    Hall, P.A.7
  • 16
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano, K. and Vousden, K.H. 2001. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7: 683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 19
    • 0034641963 scopus 로고    scopus 로고
    • Defying death after DNA damage
    • Rich, T., Allen, R.L., and Wyllie, A.H. 2000. Defying death after DNA damage. Nature 407: 777-783.
    • (2000) Nature , vol.407 , pp. 777-783
    • Rich, T.1    Allen, R.L.2    Wyllie, A.H.3
  • 21
    • 0026638951 scopus 로고
    • Apoptosis: Biochemical events and relevance to cancer chemotherapy
    • Sen, S. and D'Incalci, M. 1992. Apoptosis: Biochemical events and relevance to cancer chemotherapy. FEBS Lett. 307: 122-127.
    • (1992) FEBS Lett. , vol.307 , pp. 122-127
    • Sen, S.1    D'Incalci, M.2
  • 23
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden, K.H. and Lu, X. 2002. Live or let die: The cell's response to p53. Nat. Rev. Cancer 2: 594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 25
    • 0035265823 scopus 로고    scopus 로고
    • PUMA induces the rapid apoptosis of colorectal cancer cells
    • Yu, J., Zhang, L., Hwang, P.M., Kinzler, K.W., and Vogelstein, B. 2001. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol. Cell 7: 673-682.
    • (2001) Mol. Cell , vol.7 , pp. 673-682
    • Yu, J.1    Zhang, L.2    Hwang, P.M.3    Kinzler, K.W.4    Vogelstein, B.5
  • 26
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.