Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice

Oncogene

Volumn 15, Issue 15, 1997, Pages 1787-1795

  Jäger, Richard ^a,b   Herzer, Ute ^a   Schenkel, Johannes ^a,c   Weiher, Hans ^a,d  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b Departement Klinische Forschung   (Switzerland)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d INSTITUT FÜR DIABETESFORSCHUNG   (Germany)

Author keywords

bcl 2; Involution; Mammary gland; Transgenic mice; Tumorigenesis

Indexed keywords

PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST CELL; BREAST EPITHELIUM; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; LACTATION; MAMMARY GLAND; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALIA; MAMMARY TUMOR ONCOVIRUS; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS; ONCOVIRINAE;

EID: 0030669560     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201353     Document Type: Article

References (56)

1. Andres AC, Bchini O, Schubaur B, Dolder B, LeMeur M and Gerlinger P. (1991). Oncogene, 6, 771-779.
2. Andres AC, Zuercher G, Djonov V, Flueck M and Ziemiecki A. (1995) Int. J. Cancer, 63, 288-296.
3. Adams JM and Cory S. (1991). Science, 254, 1161-1167.
4. Bakhshi A, Jensen JP, Goldman P, Wright JJ, McBridge OW, Epstein AL and Korsmeyer SJ. (1985). Cell, 41, 899-906.
5. Bargou RC, Daniel PT, Mapara MY, Bommert K, Wagener C, Kallinich B, Royer HD and Dörken B. (1995). Int. J. Cancer, 60, 854-859.
6. Bchini O, Andres AC, Schubaur B, Mehtali M, Le Meur M, Lathe R and Gerlinger P. (1991). Endocrinology, 128, 539-546.
7. Boudreau N, Sympson CJ, Werb Z and Bissell MJ. (1995). Science, 267, 891-893.
8. Boudreau N, Werb Z and Bissell MJ. (1996). Proc. Natl. Acad. Sci., 93, 3509-3513.
9. Burdon T, Sankaran L, Wall RJ, Spencer M and Hennighausen L. (1991). J. Biol. Chem. 266, 6909-6914.
10. Chen J, Flannery JG, LaVail MM, Steinberg RH, Xu J and Simon MI. (1996). Proc. Natl. Acad. Sci., 93, 7042-7047.
11. Chirgwin JJ, Przbyla AE, MacDonald RJ and Rutter WJ. (1979). Biochemistry, 18, 5294-5299.
12. Cleary ML and Sklar J. (1985). Proc. Natl. Acad. Sci., 82, 7439-7443.
13. Debbas M and White E. (1993). Genes and Dev., 7, 546-554.
14. Eliopoulos A, Kerr DJ, Herod J, Hodgkins L, Krajewski S, Reed JC and Young LS. (1995). Oncogene, 11, 1217-1228.
15. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ and Hancock DC. (1992). Cell, 69, 119-128.
16. Fanidi A, Harrington E and Evan GI. (1992). Nature, 359, 554-556.
17. Farrow SN and Brown R. (1996). Curr. Opin. Gen and Dev., 6, 45-49.
18. Fearon ER and Vogelstein B. (1990). Cell, 61, 759-767.
19. Feng Z, Marti A, Jehn B, Altermatt HJ, Chicaiza G and Jaggi R. (1995). J. Cell Biol., 131, 1095-1103.
20. Gavrieli Y, Sherman Y and Ben-Sasson SA. (1992). J. Cell Biol., 119, 493-501.
21. Gee JMW, Robertson JFR, Ellis IO, Willsher P, McClelland RA, Hoyle HB, Kyme SR, Finlay P, Blamey RW and Nicholson RI. (1994). Int. J. Cancer, 59, 619-628.
22. Günthert U, Hofmann M, Rudy W, Reber S, Zöller M, Haußmann I, Matzku S, Wenzel A, Ponta H and Herrlich P. (1991). Cell, 65, 13-24.
23. Hadsell DL, Greenberg NM, Fligger JM, Baumrucker CR and Rosen JM. (1996). Endocrinology, 137, 321-330.
24. Hague A, Moorghen M, Hicks D, Chapman M and Paraskeva C. (1994). Oncogene, 9, 3367-3370.
25. Hale AJ, Smith CA, Sutherland LC, Stoneman VEA, Longthorne V, Culhane AC and Williams GT. (1996). Eur. J. Biochem., 236, 1-26.
26. Heermeier K, Benedict M, Li M, Furth P Nunez G and Hennighausen L. (1996). Mechanisms of Development, 56, 197-207.
27. Hogan B, Constantini F, Lacy E. (1986). Manipulating the Mouse Embryo. A Laboratory Manual. Cold Spring Harbor Press. Cold Spring Harbor, New York.
28. Howes KA, Ransom N, Papermaster DS, Lasudry JGH, Albert DM and Windle JJ. (1994). Genes and Dev., 8, 1300-1310.
29. Humphreys RC, Krajewska M, Krnacik S, Jäger R, Weiher H, Krajewski S, Reed JC and Rosen JR. (1996). Development, 122, 4013-4022.
30. Jiang S-X, Sato Y, Kuwao S and Kameya T. (1995). J. Pathol., 177, 135-138.
31. Kordon EC, McKnight RA, Jhappan C, Hennighausen L, Merlino G and Smith GH. (1995). Dev. Biol., 168, 47-61.
32. Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius V-M, Niskanen E, Nordling S and Reed JC. (1995). Cancer Res., 55, 4471-4478.
33. Lacronique V, Mignon A, Fabre M, Benoit V, Rouquet N, Molina T, Porteu A, Henrion A, Bouscary D, Varlet P, Joulin V and Kahn A. (1996). Nature Medicine, 2, 80-86.
34. Laemmli UK. (1970). Nature, 227, 680-685.
35. Leek RD, Kaklamanis L, Pezzella F, Gatter KC and Harris AL. (1994). Br. J. Cancer, 69, 135-139.
36. Li B, Kittrell FS, Medina D and Rosen JM. (1996a). Mol. Carcinog., 14, 75-83.
37. Li M, Hu J, Heermeier K, Hennighausen L and Furth P. (1996b). Cell Growth Differ., 7, 13-20.
38. Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Dano K and Werb Z. (1996). Development, 122, 181-193.
39. Marin MC, Hsu B, Stephens LC, Brisbay S and McDonnell J. (1995). Exp. Cell Res., 217, 240-247.
40. Martinou JC, Dubois-Dauphin M, Staple JK, Rodriguez I, Frankowsky H, Missotten M, Albertini P, Talabot D, Catsicas S, Pietra C and Huarte J. (1994). Neuron, 13, 1017-1030.
41. McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKearn JP and Korsmeyer SJ. (1989). Cell, 57, 79-88.
42. McDonnell TJ and Korsmeyer SJ. (1991). Nature, 349, 254-256.
43. McDonnell TJ, Troncoso P, Brisbay SM, Logothtis C, Chung LWK, Hsieh J-T, Tu SM and Campbell ML. (1992). Cancer Res., 52, 6940-6944.
44. Monaghan P, Robertson D, Amos TAS, Dyer MJS, Mason DY and Greaves MF. (1992). J. Histochem. Cytochem., 40, 1819-1825.
45. Naik P, Karrim J and Hanahan D. (1996). Genes and Dev., 10, 2105-2116.
46. Oltvai ZN, Milliman CL and Korsmeyer SJ. (1993). Cell 74, 609-619.
47. Pullan S, Wilson J, Metcalfe A, Edwards GM, Goberdhan N, Tilly J, Hickman JA, Dive C and Streuli CH. (1996). J. Cell Science, 109, 631-642.
48. Sandgren EP, Schroeder JA, Qui TH, Palmiter RD, Brinster RL and Lee DC. (1995). Cancer Res., 55, 3915-3927.
49. Sato T, Hanada M, Bodrug S, Irie S, Iwama N, Boise L, Thompson CB, Golemis E, Fong L, Wang H-G and Reed JC. (1994). Proc. Natl. Acad. Sci., 91, 9238-9242.
50. Stewart TA, Pattengale PK and Leder P. (1984). Cell, 38, 627-637.
51. Strange R, Li F, Saurer S, Burkhardt A and Friis RR. (1992). Development, 115, 49-58.
52. Walker NI, Bennett RE and Kerr JFR. (1989). Am. J. Anat., 185, 19-32.
53. Wang TTY and Phang JM. (1995). Cancer Res., 55, 2487-2489.
54. Wong P, Pineault J, Lakins J, Taillefer D, Leger J, Wang C and Tenniswood M. (1993). J. Biol. Chem., 268, 5021-5031.
55. Wong P, Taillefer D, Lakins J, Pineault J, Chader G and Tenniswood M. (1994). Eur. J. Biochem., 221, 917-925.
56. Zha H, Aime-Sempe C, Sato T, Reed JC. (1996). J. Biol. Chem., 271, 7440-7444.