-
1
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/ cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA (1996) The dorsoventral regulatory gene cassette spatzle/Toll/ cactus controls the potent antifungal response in Drosophila adults. Cell 86:973-983
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
2
-
-
0030666222
-
Innate immunity: The virtues of a nonclonal system of recognition
-
Medzhitov R, Janeway CJ (1997) Innate immunity: the virtues of a nonclonal system of recognition. Cell 91:295-298
-
(1997)
Cell
, vol.91
, pp. 295-298
-
-
Medzhitov, R.1
Janeway, C.J.2
-
3
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124:783-801
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
5
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5:730-737
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
6
-
-
22544455673
-
Cell type-specific involvement of RIG-I in antiviral response
-
Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, Matsui K, Tsujimura T, Takeda K, Fujita T, Takeuchi O, Akira S (2005) Cell type-specific involvement of RIG-I in antiviral response. Immunity 23:19-28
-
(2005)
Immunity
, vol.23
, pp. 19-28
-
-
Kato, H.1
Sato, S.2
Yoneyama, M.3
Yamamoto, M.4
Uematsu, S.5
Matsui, K.6
Tsujimura, T.7
Takeda, K.8
Fujita, T.9
Takeuchi, O.10
Akira, S.11
-
7
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 189:1777-1782
-
(1999)
J Exp Med
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
9
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11:443-451
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
10
-
-
0036498687
-
Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?
-
Netea MG, van Deuren M, Kullberg BJ, Cavaillon JM, Van der Meer JW (2002) Does the shape of lipid A determine the interaction of LPS with Toll-like receptors? Trends Immunol 23:135-139
-
(2002)
Trends Immunol
, vol.23
, pp. 135-139
-
-
Netea, M.G.1
Van Deuren, M.2
Kullberg, B.J.3
Cavaillon, J.M.4
Van Der Meer, J.W.5
-
11
-
-
5044249323
-
Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis
-
Hashimoto M, Asai Y, Ogawa T (2004) Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis. Int Immunol 16:1431-1437
-
(2004)
Int Immunol
, vol.16
, pp. 1431-1437
-
-
Hashimoto, M.1
Asai, Y.2
Ogawa, T.3
-
12
-
-
0742307236
-
Toll receptor families: Structure and function
-
Akira S (2004) Toll receptor families: structure and function. Semin Immunol 16:1-2
-
(2004)
Semin Immunol
, vol.16
, pp. 1-2
-
-
Akira, S.1
-
13
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S (2001) Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 13:933-940
-
(2001)
Int Immunol
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
14
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, Modlin RL, Akira S (2002) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 169:10-14
-
(2002)
J Immunol
, vol.169
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
15
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
-
Alexopoulou L, Thomas V, Schnare M, Lobet Y, Anguita J, Schoen RT, Medzhitov R, Fikrig E, Flavell RA (2002) Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med 8:878-884
-
(2002)
Nat Med
, vol.8
, pp. 878-884
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
Schoen, R.T.6
Medzhitov, R.7
Fikrig, E.8
Flavell, R.A.9
-
16
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
Hoebe K, Georgel P, Rutschmann S, Du X, Mudd S, Crozat K, Sovath S, Shamel L, Hartung T, Zahringer U, Beutler B (2005) CD36 is a sensor of diacylglycerides. Nature 433:523-527
-
(2005)
Nature
, vol.433
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
Du, X.4
Mudd, S.5
Crozat, K.6
Sovath, S.7
Shamel, L.8
Hartung, T.9
Zahringer, U.10
Beutler, B.11
-
17
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410:1099-1103
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
18
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz AT, Navas TA, Lyons S, Godowski PJ, Madara JL (2001) Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol 167:1882-1885
-
(2001)
J Immunol
, vol.167
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
19
-
-
10744226016
-
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease
-
Hawn TR, Verbon A, Lettinga KD, Zhao LP, Li SS, Laws RJ, Skerrett SJ, Beutler B, Schroeder L, Nachman A, Ozinsky A, Smith KD, Aderem A (2003) A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med 198: 1563-1572
-
(2003)
J Exp Med
, vol.198
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
Ozinsky, A.11
Smith, K.D.12
Aderem, A.13
-
20
-
-
20144366015
-
Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam
-
Dunstan SJ, Hawn TR, Hue NT, Parry CP, Ho VA, Vinh H, Diep TS, House D, Wain J, Aderem A, Hien TT, Farrar JJ (2005) Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam. J Infect Dis 191:1068-1071
-
(2005)
J Infect Dis
, vol.191
, pp. 1068-1071
-
-
Dunstan, S.J.1
Hawn, T.R.2
Hue, N.T.3
Parry, C.P.4
Ho, V.A.5
Vinh, H.6
Diep, T.S.7
House, D.8
Wain, J.9
Aderem, A.10
Hien, T.T.11
Farrar, J.J.12
-
21
-
-
21544448078
-
Evasion of Toll-like receptor 5 by flagellated bacteria
-
Andersen-Nissen E, Smith KD, Strobe KL, Barrett SL, Cookson BT, Logan SM, Aderem A (2005) Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci USA 102:9247-9252
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9247-9252
-
-
Andersen-Nissen, E.1
Smith, K.D.2
Strobe, K.L.3
Barrett, S.L.4
Cookson, B.T.5
Logan, S.M.6
Aderem, A.7
-
22
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408:740-745
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
23
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavell RA, Ghosh S (2004) A toll-like receptor that prevents infection by uropathogenic bacteria. Science 303:1522-1526
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
25
-
-
0037025994
-
Dectin-1 is a major beta-glucan receptor on macrophages
-
Brown GD, Taylor PR, Reid DM, Willment JA, Williams DL, Martinez-Pomares L, Wong SY, Gordon S (2002) Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med 196:407-412
-
(2002)
J Exp Med
, vol.196
, pp. 407-412
-
-
Brown, G.D.1
Taylor, P.R.2
Reid, D.M.3
Willment, J.A.4
Williams, D.L.5
Martinez-Pomares, L.6
Wong, S.Y.7
Gordon, S.8
-
26
-
-
0038558249
-
Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2
-
Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 197:1107-1117
-
(2003)
J Exp Med
, vol.197
, pp. 1107-1117
-
-
Gantner, B.N.1
Simmons, R.M.2
Canavera, S.J.3
Akira, S.4
Underhill, D.M.5
-
27
-
-
20244363662
-
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
-
Rogers NC, Slack EC, Edwards AD, Nolte MA, Schulz O, Schweighoffer E, Williams DL, Gordon S, Tybulewicz VL, Brown GD, Reis ESC (2005) Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22:507-517
-
(2005)
Immunity
, vol.22
, pp. 507-517
-
-
Rogers, N.C.1
Slack, E.C.2
Edwards, A.D.3
Nolte, M.A.4
Schulz, O.5
Schweighoffer, E.6
Williams, D.L.7
Gordon, S.8
Tybulewicz, V.L.9
Brown, G.D.10
Reis, E.S.C.11
-
28
-
-
27144521657
-
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
-
Underhill DM, Rossnagle E, Lowell CA, Simmons RM (2005) Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 106:2543-2550
-
(2005)
Blood
, vol.106
, pp. 2543-2550
-
-
Underhill, D.M.1
Rossnagle, E.2
Lowell, C.A.3
Simmons, R.M.4
-
29
-
-
4844227051
-
Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites
-
Gazzinelli RT, Ropert C, Campos MA (2004) Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites. Immunol Rev 201:9-25
-
(2004)
Immunol Rev
, vol.201
, pp. 9-25
-
-
Gazzinelli, R.T.1
Ropert, C.2
Campos, M.A.3
-
30
-
-
20644433342
-
TLR11 activation of dendritic cells by a protozoan profilin-like protein
-
Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, Serhan CN, Hayden MS, Hieny S, Sutterwala FS, Flavell RA, Ghosh S, Sher A (2005) TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 308(5728):1626-1629
-
(2005)
Science
, vol.308
, Issue.5728
, pp. 1626-1629
-
-
Yarovinsky, F.1
Zhang, D.2
Andersen, J.F.3
Bannenberg, G.L.4
Serhan, C.N.5
Hayden, M.S.6
Hieny, S.7
Sutterwala, F.S.8
Flavell, R.A.9
Ghosh, S.10
Sher, A.11
-
31
-
-
19944430901
-
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S (2005) Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med 201:19-25
-
(2005)
J Exp Med
, vol.201
, pp. 19-25
-
-
Coban, C.1
Ishii, K.J.2
Kawai, T.3
Hemmi, H.4
Sato, S.5
Uematsu, S.6
Yamamoto, M.7
Takeuchi, O.8
Itagaki, S.9
Kumar, N.10
Horii, T.11
Akira, S.12
-
32
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW (2000) Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 1:398-401
-
(2000)
Nat Immunol
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
33
-
-
0034768425
-
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
-
Haynes LM, Moore DD, Kurt-Jones EA, Finberg RW, Anderson LJ, Tripp RA (2001) Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus. J Virol 75:10730-10737
-
(2001)
J Virol
, vol.75
, pp. 10730-10737
-
-
Haynes, L.M.1
Moore, D.D.2
Kurt-Jones, E.A.3
Finberg, R.W.4
Anderson, L.J.5
Tripp, R.A.6
-
34
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with toll-like receptor 4
-
Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR (2002) Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci USA 99:2281-2286
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
35
-
-
0036340341
-
Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling
-
Bieback K, Lien E, Klagge IM, Avota E, Schneider-Schaulies J, Duprex WP, Wagner H, Kirschning CJ, Ter Meulen V, Schneider-Schaulies S (2002) Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling. J Virol 76:8729-8736
-
(2002)
J Virol
, vol.76
, pp. 8729-8736
-
-
Bieback, K.1
Lien, E.2
Klagge, I.M.3
Avota, E.4
Schneider-Schaulies, J.5
Duprex, W.P.6
Wagner, H.7
Kirschning, C.J.8
Ter Meulen, V.9
Schneider-Schaulies, S.10
-
36
-
-
0345505220
-
Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2
-
Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, Golenbock DT, Finberg RW (2003) Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol 77:4588-4596
-
(2003)
J Virol
, vol.77
, pp. 4588-4596
-
-
Compton, T.1
Kurt-Jones, E.A.2
Boehme, K.W.3
Belko, J.4
Latz, E.5
Golenbock, D.T.6
Finberg, R.W.7
-
37
-
-
0842342607
-
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis
-
Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW (2004) Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci USA 101:1315-1320
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1315-1320
-
-
Kurt-Jones, E.A.1
Chan, M.2
Zhou, S.3
Wang, J.4
Reed, G.5
Bronson, R.6
Arnold, M.M.7
Knipe, D.M.8
Finberg, R.W.9
-
38
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413:732-738
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
39
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent tolllike receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S (2003) Role of adaptor TRIF in the MyD88-independent tolllike receptor signaling pathway. Science 301:640-643
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
40
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, Crozat K, Mudd S, Shamel L, Sovath S, Goode J, Alexopoulou L, Flavell RA, Beutler B (2004) Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 101:3516-3521
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
Du, X.4
Hoebe, K.5
Crozat, K.6
Mudd, S.7
Shamel, L.8
Sovath, S.9
Goode, J.10
Alexopoulou, L.11
Flavell, R.A.12
Beutler, B.13
-
41
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA (2004) Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 10: 1366-1373
-
(2004)
Nat Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
42
-
-
0042123694
-
Tolllike receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells
-
Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A (2003) Tolllike receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med 198:513-520
-
(2003)
J Exp Med
, vol.198
, pp. 513-520
-
-
Lund, J.1
Sato, A.2
Akira, S.3
Medzhitov, R.4
Iwasaki, A.5
-
43
-
-
3142683548
-
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function
-
Krug A, French AR, Barchet W, Fischer JA, Dzionek A, Pingel JT, Orihuela MM, Akira S, Yokoyama WM, Colonna M (2004) TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity 21:107-119
-
(2004)
Immunity
, vol.21
, pp. 107-119
-
-
Krug, A.1
French, A.R.2
Barchet, W.3
Fischer, J.A.4
Dzionek, A.5
Pingel, J.T.6
Orihuela, M.M.7
Akira, S.8
Yokoyama, W.M.9
Colonna, M.10
-
44
-
-
0842328805
-
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
-
Krug A, Luker GD, Barchet W, Leib DA, Akira S, Colonna M (2004) herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood 103:1433-1437
-
(2004)
Blood
, vol.103
, pp. 1433-1437
-
-
Krug, A.1
Luker, G.D.2
Barchet, W.3
Leib, D.A.4
Akira, S.5
Colonna, M.6
-
45
-
-
0036008014
-
Small antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, Horiuchi T, Tomizawa H, Takeda K, Akira S (2002) Small antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3:196-200
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
46
-
-
0037013830
-
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets
-
Ito T, Amakawa R, Kaisho T, Hemmi H, Tajima K, Uehira K, Ozaki Y, Tomizawa H, Akira S, Fukuhara S (2002) Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med 195:1507-1512
-
(2002)
J Exp Med
, vol.195
, pp. 1507-1512
-
-
Ito, T.1
Amakawa, R.2
Kaisho, T.3
Hemmi, H.4
Tajima, K.5
Uehira, K.6
Ozaki, Y.7
Tomizawa, H.8
Akira, S.9
Fukuhara, S.10
-
47
-
-
0037460116
-
Recognition of pathogen-associated molecular patterns by TLR family
-
Akira S, Hemmi H (2003) Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 85:85-95
-
(2003)
Immunol Lett
, vol.85
, pp. 85-95
-
-
Akira, S.1
Hemmi, H.2
-
48
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis E, Sousa C (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529-1531
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis, E.5
Sousa, C.6
-
49
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S (2004) Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303:1526-1529
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
50
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng T, Barton GM, Flavell RA, Medzhitov R (2002) The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420:329-333
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
51
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S (2002) Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420:324-329
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
Takeda, K.11
Akira, S.12
-
52
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115-122
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
53
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S (2002) Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 169:6668-6672
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
54
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
-
Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T (2003) TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol 4:161-167
-
(2003)
Nat Immunol
, vol.4
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
55
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B (2003) Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424:743-748
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
Crozat, K.11
Sovath, S.12
Han, J.13
Beutler, B.14
-
56
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, Takeuchi O, Takeda K, Akira S (2003) TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 4:1144-1150
-
(2003)
Nat Immunol
, vol.4
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
Takeuchi, O.7
Takeda, K.8
Akira, S.9
-
57
-
-
0042591216
-
TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
-
Bin LH, Xu LG, Shu HB (2003) TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J Biol Chem 278:24526-24532
-
(2003)
J Biol Chem
, vol.278
, pp. 24526-24532
-
-
Bin, L.H.1
Xu, L.G.2
Shu, H.B.3
-
58
-
-
0345991221
-
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta
-
Oshiumi H, Sasai M, Shida K, Fujita T, Matsumoto M, Seya T (2003) TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. J Biol Chem 278:49751-49762
-
(2003)
J Biol Chem
, vol.278
, pp. 49751-49762
-
-
Oshiumi, H.1
Sasai, M.2
Shida, K.3
Fujita, T.4
Matsumoto, M.5
Seya, T.6
-
59
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300:1148-1151
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
TenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
60
-
-
0038393016
-
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4:491-496
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
61
-
-
0345827590
-
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
-
McWhirter SM, Fitzgerald KA, Rosains J, Rowe DC, Golenbock DT, Maniatis T (2004) IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc Natl Acad Sci USA 101:233-238
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 233-238
-
-
McWhirter, S.M.1
Fitzgerald, K.A.2
Rosains, J.3
Rowe, D.C.4
Golenbock, D.T.5
Maniatis, T.6
-
62
-
-
3042647375
-
Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection
-
Perry AK, Chow EK, Goodnough JB, Yeh WC, Cheng G (2004) Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J Exp Med 199:1651-1658
-
(2004)
J Exp Med
, vol.199
, pp. 1651-1658
-
-
Perry, A.K.1
Chow, E.K.2
Goodnough, J.B.3
Yeh, W.C.4
Cheng, G.5
-
63
-
-
4344566281
-
The roles of two IkappaB Kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection
-
Hemmi H, Takeuchi O, Sato S, Yamamoto M, Kaisho T, Sanjo H, Kawai T, Hoshino K, Takeda K, Akira S (2004) The roles of two IkappaB Kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J Exp Med 199:1641-1650
-
(2004)
J Exp Med
, vol.199
, pp. 1641-1650
-
-
Hemmi, H.1
Takeuchi, O.2
Sato, S.3
Yamamoto, M.4
Kaisho, T.5
Sanjo, H.6
Kawai, T.7
Hoshino, K.8
Takeda, K.9
Akira, S.10
-
64
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K, Akira S (2003) Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 171:4304-4310
-
(2003)
J Immunol
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
Akira, S.7
-
65
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T, Takeuchi O, Fujita T, Inoue J, Muhlradt PF, Sato S, Hoshino K, Akira S (2001) Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J Immunol 167:5887-5894
-
(2001)
J Immunol
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
66
-
-
4344613405
-
Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling
-
Gohda J, Matsumura T, Inoue J (2004) Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling. J Immunol 173:2913-2917
-
(2004)
J Immunol
, vol.173
, pp. 2913-2917
-
-
Gohda, J.1
Matsumura, T.2
Inoue, J.3
-
67
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappaB activation
-
Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, Tschopp J (2004) RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappaB activation. Nat Immunol 5:503-507
-
(2004)
Nat Immunol
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
Tschopp, J.7
-
68
-
-
17644372733
-
IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
-
Liu YJ (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 23:275-306
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 275-306
-
-
Liu, Y.J.1
-
69
-
-
0037443644
-
The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
-
Hemmi H, Kaisho T, Takeda K, Akira S (2003) The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J Immunol 170:3059-3064
-
(2003)
J Immunol
, vol.170
, pp. 3059-3064
-
-
Hemmi, H.1
Kaisho, T.2
Takeda, K.3
Akira, S.4
-
70
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, Yamamoto M, Terai K, Matsuda M, Inoue J, Uematsu S, Takeuchi O, Akira S (2004) Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5:1061-1068
-
(2004)
Nat Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
Yamamoto, M.6
Terai, K.7
Matsuda, M.8
Inoue, J.9
Uematsu, S.10
Takeuchi, O.11
Akira, S.12
-
71
-
-
7444250116
-
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
-
Honda K, Yanai H, Mizutani T, Negishi H, Shimada N, Suzuki N, Ohba Y, Takaoka A, Yeh WC, Taniguchi T (2004) Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. Proc Natl Acad Sci USA 101:15416-15421
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15416-15421
-
-
Honda, K.1
Yanai, H.2
Mizutani, T.3
Negishi, H.4
Shimada, N.5
Suzuki, N.6
Ohba, Y.7
Takaoka, A.8
Yeh, W.C.9
Taniguchi, T.10
-
72
-
-
27744534928
-
Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses
-
Yang K, Puel A, Zhang S, Eidenschenk C, Ku CL, Casrouge A, Picard C, von Bernuth H, Senechal B, Plancoulaine S, Al-Hajjar S, Al-Ghonaium A, Marodi L, Davidson D, Speert D, Roifman C, Garty BZ, Ozinsky A, Barrat FJ, Coffman RL, Miller RL, Li X, Lebon P, Rodriguez-Gallego C, Chapel H, Geissmann F, Jouanguy E, Casanova JL (2005) Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity 23:465-478
-
(2005)
Immunity
, vol.23
, pp. 465-478
-
-
Yang, K.1
Puel, A.2
Zhang, S.3
Eidenschenk, C.4
Ku, C.L.5
Casrouge, A.6
Picard, C.7
Von Bernuth, H.8
Senechal, B.9
Plancoulaine, S.10
Al-Hajjar, S.11
Al-Ghonaium, A.12
Marodi, L.13
Davidson, D.14
Speert, D.15
Roifman, C.16
Garty, B.Z.17
Ozinsky, A.18
Barrat, F.J.19
Coffman, R.L.20
Miller, R.L.21
Li, X.22
Lebon, P.23
Rodriguez-Gallego, C.24
Chapel, H.25
Geissmann, F.26
Jouanguy, E.27
Casanova, J.L.28
more..
-
73
-
-
20244388983
-
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- And TLR9-mediated interferon-{alpha} induction
-
Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S (2005) Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. J Exp Med 201:915-923
-
(2005)
J Exp Med
, vol.201
, pp. 915-923
-
-
Uematsu, S.1
Sato, S.2
Yamamoto, M.3
Hirotani, T.4
Kato, H.5
Takeshita, F.6
Matsuda, M.7
Coban, C.8
Ishii, K.J.9
Kawai, T.10
Takeuchi, O.11
Akira, S.12
-
74
-
-
2442689141
-
Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells
-
Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman, DM, Ozato K (2004) Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 172:6820-6827
-
(2004)
J Immunol
, vol.172
, pp. 6820-6827
-
-
Tsujimura, H.1
Tamura, T.2
Kong, H.J.3
Nishiyama, A.4
Ishii, K.J.5
Klinman, D.M.6
Ozato, K.7
-
75
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting JP, Kastner DL, Hoffman HM (2006) CATERPILLERs, pyrin and hereditary immunological disorders. Nat Rev Immunol 6:183-195
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
76
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411:603-606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
77
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, Ogura Y, Kawasaki A, Fukase K, Kusumoto S, Valvano MA, Foster SJ, Mak TW, Nunez G, Inohara N (2003) An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 4:702-707
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
Ogura, Y.7
Kawasaki, A.8
Fukase, K.9
Kusumoto, S.10
Valvano, M.A.11
Foster, S.J.12
Mak, T.W.13
Nunez, G.14
Inohara, N.15
-
78
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J, Fukase K, Inamura S, Kusumoto S, Hashimoto M, Foster SJ, Moran AP, Fernandez-Luna JL, Nunez G (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278:5509-5512
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
Fukase, K.7
Inamura, S.8
Kusumoto, S.9
Hashimoto, M.10
Foster, S.J.11
Moran, A.P.12
Fernandez-Luna, J.L.13
Nunez, G.14
-
79
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ (2003) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278:8869-8872
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
Philpott, D.J.7
Sansonetti, P.J.8
-
80
-
-
0037075551
-
RICK/Rip2/ CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi K, Inohara, N, Hernandez LD, Galan JE, Nunez G, Janeway CA, Medzhitov R, Flavell RA (2002) RICK/Rip2/ CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416:194-199
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.D.3
Galan, J.E.4
Nunez, G.5
Janeway, C.A.6
Medzhitov, R.7
Flavell, R.A.8
-
81
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott DW, Wilkins A, Asara JM, Cantley LC (2004) The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 14:2217-2227
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
82
-
-
0345826149
-
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
-
Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit VM (2004) Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature 427:167-171
-
(2004)
Nature
, vol.427
, pp. 167-171
-
-
Zhou, H.1
Wertz, I.2
O'Rourke, K.3
Ultsch, M.4
Seshagiri, S.5
Eby, M.6
Xiao, W.7
Dixit, V.M.8
-
83
-
-
0034964518
-
CLAN, a novel human CED-4-like gene
-
Damiano JS, Stehlik C, Pio F, Godzik A, Reed JC (2001) CLAN, a novel human CED-4-like gene. Genomics 75:77-83
-
(2001)
Genomics
, vol.75
, pp. 77-83
-
-
Damiano, J.S.1
Stehlik, C.2
Pio, F.3
Godzik, A.4
Reed, J.C.5
-
84
-
-
3142674847
-
Heterotypic interactions among NACHT domains: Implications for regulation of innate immune responses
-
Damiano JS, Oliveira V, Welsh K, Reed JC (2004) Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses. Biochem J 381:213-219
-
(2004)
Biochem J
, vol.381
, pp. 213-219
-
-
Damiano, J.S.1
Oliveira, V.2
Welsh, K.3
Reed, J.C.4
-
85
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, Roose-Girma M, Erickson S, Dixit VM (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430:213-218
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
86
-
-
0041355281
-
CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways
-
Stehlik C, Hayashi H, Pio F, Godzik A, Reed JC (2003) CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways. J Biol Chem 278:31941-31949
-
(2003)
J Biol Chem
, vol.278
, pp. 31941-31949
-
-
Stehlik, C.1
Hayashi, H.2
Pio, F.3
Godzik, A.4
Reed, J.C.5
-
87
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10:417-426
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
89
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F, Tschopp J (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-574
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
90
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440:233-236
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfield, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
Bertin, J.11
Coyle, A.12
Grant, E.P.13
Akira, S.14
Nunez, G.15
-
91
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228-232
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
92
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440:237-241
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
93
-
-
0037228017
-
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
-
Diez E, Lee SH, Gauthier S, Yaraghi Z, Tremblay M, Vidal S, Gros P (2003) Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat Genet 33:55-60
-
(2003)
Nat Genet
, vol.33
, pp. 55-60
-
-
Diez, E.1
Lee, S.H.2
Gauthier, S.3
Yaraghi, Z.4
Tremblay, M.5
Vidal, S.6
Gros, P.7
-
94
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, Kuida K, Mariathasan S, Dixit VM, Flavell RA, Dietrich WF, Roy CR (2006) The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol 7:318-325
-
(2006)
Nat Immunol
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
Kuida, K.7
Mariathasan, S.8
Dixit, V.M.9
Flavell, R.A.10
Dietrich, W.F.11
Roy, C.R.12
-
95
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
Miceli-Richard C, Lesage S, Rybojad M, Prieur AM, Manouvrier-Hanu S, Hafner R, Chamaillard M, Zouali H, Thomas G, Hugot JP (2001) CARD15 mutations in Blau syndrome. Nat Genet 29:19-20
-
(2001)
Nat Genet
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
Lesage, S.2
Rybojad, M.3
Prieur, A.M.4
Manouvrier-Hanu, S.5
Hafner, R.6
Chamaillard, M.7
Zouali, H.8
Thomas, G.9
Hugot, J.P.10
-
96
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD (2001) Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 29:301-305
-
(2001)
Nat Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
97
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
-
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, Stein L, Russo R, Goldsmith D, Dent P, Rosenberg HF, Austin F, Remmers EF, Balow JE Jr, Rosenzweig S, Komarow H, Shoham NG, Wood G, Jones J, Mangra N, Carrero H, Adams BS, Moore TL, Schikler K, Hoffman H, Lovell DJ, Lipnick R, Barron K, O'Shea JJ, Kastner DL, Goldbach-Mansky R (2002) De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum 46:3340-3348
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
Stein, L.7
Russo, R.8
Goldsmith, D.9
Dent, P.10
Rosenberg, H.F.11
Austin, F.12
Remmers, E.F.13
Balow Jr., J.E.14
Rosenzweig, S.15
Komarow, H.16
Shoham, N.G.17
Wood, G.18
Jones, J.19
Mangra, N.20
Carrero, H.21
Adams, B.S.22
Moore, T.L.23
Schikler, K.24
Hoffman, H.25
Lovell, D.J.26
Lipnick, R.27
Barron, K.28
O'Shea, J.J.29
Kastner, D.L.30
Goldbach-Mansky, R.31
more..
-
98
-
-
0037108346
-
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains
-
Harton JA, Linhoff MW, Zhang J, Ting JP (2002) Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. J Immunol 169:4088-4093
-
(2002)
J Immunol
, vol.169
, pp. 4088-4093
-
-
Harton, J.A.1
Linhoff, M.W.2
Zhang, J.3
Ting, J.P.4
-
99
-
-
17644396670
-
CATERPILLER: A novel gene family important in immunity, cell death, and diseases
-
Ting JP, Davis BK (2005) CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annu Rev Immunol 23:387-414
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 387-414
-
-
Ting, J.P.1
Davis, B.K.2
-
100
-
-
0027490172
-
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
-
Steimle V, Otten LA, Zufferey M, Mach B (1993) Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75:135-146
-
(1993)
Cell
, vol.75
, pp. 135-146
-
-
Steimle, V.1
Otten, L.A.2
Zufferey, M.3
Mach, B.4
-
101
-
-
31344461659
-
Innate immune recognition of viral infection
-
Kawai T, Akira S (2006) Innate immune recognition of viral infection. Nat Immunol 7:131-137
-
(2006)
Nat Immunol
, vol.7
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
102
-
-
0037154176
-
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
-
Kang DC, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, Fisher PB (2002) mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci USA 99:637-642
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 637-642
-
-
Kang, D.C.1
Gopalkrishnan, R.V.2
Wu, Q.3
Jankowsky, E.4
Pyle, A.M.5
Fisher, P.B.6
-
103
-
-
0037076217
-
Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation
-
Kovacsovics M, Martinon F, Micheau O, Bodmer JL, Hofmann K, Tschopp J (2002) Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation. Curr Biol 12:838-843
-
(2002)
Curr Biol
, vol.12
, pp. 838-843
-
-
Kovacsovics, M.1
Martinon, F.2
Micheau, O.3
Bodmer, J.L.4
Hofmann, K.5
Tschopp, J.6
-
104
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
-
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, Goodbourn S, Randall RE (2004) The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc Natl Acad Sci USA 101:17264-17269
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
Goodbourn, S.6
Randall, R.E.7
-
105
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T (2005) Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175:2851-2858
-
(2005)
J Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
Taira, K.6
Foy, E.7
Loo, Y.M.8
Gale Jr., M.9
Akira, S.10
Yonehara, S.11
Kato, A.12
Fujita, T.13
-
106
-
-
26844503987
-
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
-
Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA (2005) The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J Immunol 175:5260-5268
-
(2005)
J Immunol
, vol.175
, pp. 5260-5268
-
-
Rothenfusser, S.1
Goutagny, N.2
DiPerna, G.3
Gong, M.4
Monks, B.G.5
Schoenemeyer, A.6
Yamamoto, M.7
Akira, S.8
Fitzgerald, K.A.9
-
107
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6:981-988
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
108
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122:669-682
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
109
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB (2005) VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell 19:727-740
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
110
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J (2005) Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167-1172
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
Tschopp, J.7
-
111
-
-
0034730146
-
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling
-
Bowie A, Kiss-Toth E, Symons JA, Smith GL, Dower SK, O'Neill LA (2000) A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling. Proc Natl Acad Sci USA 97:10162-10167
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10162-10167
-
-
Bowie, A.1
Kiss-Toth, E.2
Symons, J.A.3
Smith, G.L.4
Dower, S.K.5
O'Neill, L.A.6
-
112
-
-
0037415598
-
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense
-
Harte MT, Haga IR, Maloney G, Gray P, Reading PC, Bartlett NW, Smith GL, Bowie A, O'Neill LA (2003) The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. J Exp Med 197:343-351
-
(2003)
J Exp Med
, vol.197
, pp. 343-351
-
-
Harte, M.T.1
Haga, I.R.2
Maloney, G.3
Gray, P.4
Reading, P.C.5
Bartlett, N.W.6
Smith, G.L.7
Bowie, A.8
O'Neill, L.A.9
-
113
-
-
17144366260
-
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence
-
Stack J, Haga IR, Schroder M, Bartlett NW, Maloney G, Reading PC, Fitzgerald KA, Smith GL, Bowie AG (2005) Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence. J Exp Med 201:1007-1018
-
(2005)
J Exp Med
, vol.201
, pp. 1007-1018
-
-
Stack, J.1
Haga, I.R.2
Schroder, M.3
Bartlett, N.W.4
Maloney, G.5
Reading, P.C.6
Fitzgerald, K.A.7
Smith, G.L.8
Bowie, A.G.9
-
114
-
-
20044379559
-
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling
-
Foy E, Li K, Sumpter R Jr, Loo YM, Johnson CL, Wang C, Fish PM, Yoneyama M, Fujita T, Lemon SM, Gale M Jr (2005) Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci USA 102:2986-2991
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2986-2991
-
-
Foy, E.1
Li, K.2
Sumpter Jr., R.3
Loo, Y.M.4
Johnson, C.L.5
Wang, C.6
Fish, P.M.7
Yoneyama, M.8
Fujita, T.9
Lemon, S.M.10
Gale Jr., M.11
-
115
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li XD, Sun L, Seth RB, Pineda G, Chen ZJ (2005) Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc Natl Acad Sci USA 102:17717-17722
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
116
-
-
0037321024
-
Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation
-
Kawane K, Fukuyama H, Yoshida H, Nagase H, Ohsawa Y, Uchiyama Y, Okada K, Iida T, Nagata S (2003) Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation. Nat Immunol 4:138-144
-
(2003)
Nat Immunol
, vol.4
, pp. 138-144
-
-
Kawane, K.1
Fukuyama, H.2
Yoshida, H.3
Nagase, H.4
Ohsawa, Y.5
Uchiyama, Y.6
Okada, K.7
Iida, T.8
Nagata, S.9
-
117
-
-
12344290452
-
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
-
Yoshida H, Okabe Y, Kawane K, Fukuyama H, Nagata S (2005) Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol 6:49-56
-
(2005)
Nat Immunol
, vol.6
, pp. 49-56
-
-
Yoshida, H.1
Okabe, Y.2
Kawane, K.3
Fukuyama, H.4
Nagata, S.5
-
118
-
-
0033515098
-
Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides
-
Suzuki K, Mori A, Ishii KJ, Saito J, Singer DS, Klinman DM, Krause PR, Kohn LD (1999) Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides. Proc Natl Acad Sci USA 96:2285-2290
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2285-2290
-
-
Suzuki, K.1
Mori, A.2
Ishii, K.J.3
Saito, J.4
Singer, D.S.5
Klinman, D.M.6
Krause, P.R.7
Kohn, L.D.8
-
119
-
-
0035451081
-
Genomic DNA released by dying cells induces the maturation of APCs
-
Ishii KJ, Suzuki K, Coban C, Takeshita F, Itoh Y, Matoba H, Kohn LD, Klinman DM (2001) Genomic DNA released by dying cells induces the maturation of APCs. J Immunol 167:2602-2607
-
(2001)
J Immunol
, vol.167
, pp. 2602-2607
-
-
Ishii, K.J.1
Suzuki, K.2
Coban, C.3
Takeshita, F.4
Itoh, Y.5
Matoba, H.6
Kohn, L.D.7
Klinman, D.M.8
-
120
-
-
29244471275
-
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii KJ, Coban C, Kato H, Takahashi K, Torii Y, Takeshita F, Ludwig H, Sutter G, Suzuki K, Hemmi H, Sato S, Yamamoto M, Uematsu S, Kawai T, Takeuchi O, Akira S (2006) A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 7:40-48
-
(2006)
Nat Immunol
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
Coban, C.2
Kato, H.3
Takahashi, K.4
Torii, Y.5
Takeshita, F.6
Ludwig, H.7
Sutter, G.8
Suzuki, K.9
Hemmi, H.10
Sato, S.11
Yamamoto, M.12
Uematsu, S.13
Kawai, T.14
Takeuchi, O.15
Akira, S.16
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