Human TLR-7-, -8-, and -9-mediated induction of IFN-α/β and -λ Is IRAK-4 dependent and redundant for protective immunity to viruses

Immunity

Volumn 23, Issue 5, 2005, Pages 465-478

  Yang, Kun ^a,b   Puel, Anne ^a   Zhang, Shenying ^a,b   Eidenschenk, Céline ^a   Ku, Cheng Lung ^a   Casrouge, Armanda ^a   Picard, Capucine ^a,c   Von Bernuth, Horst ^a   Senechal, Brigitte ^c   Plancoulaine, Sabine ^a   Al Hajjar, Sami ^d   Al Ghonaium, Abdulaziz ^d   Maródi, László ^e   Davidson, Donald ^f   Speert, David ^f   Roifman, Chaim ^g   Garty, Ben Zion ^h   Ozinsky, Adrian ⁱ   Barrat, Franck J ^j   Coffman, Robert L ^j   Miller, Richard L ^k   Li, Xiaoxia ^l   Lebon, Pierre ^m   Rodriguez Gallego, Carlos ⁿ   Chapel, Helen ^o   Geissmann, Frédéric ^c   Jouanguy, Emmanuelle ^a,b   Casanova, Jean Laurent ^a,b,c   more..

^a IMAGINE INSTITUTE   (France)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^e UNIVERSITY OF DEBRECEN   (Hungary)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g HOSPITAL FOR SICK CHILDREN   (Canada)

^h SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

ⁱ INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^j Dynavax Technologies Corporation   (United States)

^k 3M COMPANY   (United States)

^l LERNER RESEARCH INSTITUTE   (United States)

^m HÔPITAL SAINT VINCENT DE PAUL   (France)

ⁿ HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^o OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; BETA INTERFERON; GAMMA INTERFERON; INTERFERON; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 3 AGONIST; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 AGONIST; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; VIRUS INFECTION;

FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERFERONS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLY I-C; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS; VIRUS DISEASES; VIRUSES;

EID: 27744534928     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.09.016     Document Type: Article

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