VISA is an adapter protein required for virus-triggered IFN-β signaling

Molecular Cell

Volumn 19, Issue 6, 2005, Pages 727-740

  Xu, Liang Guo ^a   Wang, Yan Yi ^b   Han, Ke Jun ^a   Li, Lian Yun ^b   Zhai, Zhonghe ^b   Shu, Hong Bing ^a,b,c  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b PEKING UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; CYTOKINE; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VIRUS INDUCED SIGNALING ADAPTOR PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CYTOKINE RELEASE; CYTOPLASM; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; HUMANS; INTERFERON-BETA; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROMOTER REGIONS (GENETICS); RATS; RNA HELICASES; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR-ALPHA; VIRUSES;

EID: 24944538819     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2005.08.014     Document Type: Article

References (43)

1. L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 2001 732 738
2. R.H. Arch, R.W. Gedrich, and C.B. Thompson Translocation of TRAF proteins regulates apoptotic threshold of cells Biochem. Biophys. Res. Commun. 272 2000 936 945
3. F.A. Barr, H.H. Sillje, and E.A. Nigg Polo-like kinases and the orchestration of cell division Nat. Rev. Mol. Cell Biol. 5 2004 429 440
4. L.M. Boucher, L.E. Marengere, Y. Lu, S. Thukral, and T.W. Mak Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily Biochem. Biophys. Res. Commun. 233 1997 592 600
5. J.R. Bradley, and J.S. Pober Tumor necrosis factor receptor-associated factors (TRAFs) Oncogene 20 2001 6482 6491
6. S.R. Brodeur, G. Cheng, D. Baltimore, and D.A. Thorley-Lawson Localization of the major NF-kappaB-activating site and the sole TRAF3 binding site of LMP-1 defines two distinct signaling motifs J. Biol. Chem. 272 1997 19777 19784
7. K.D. Brown, B.S. Hostager, and G.A. Bishop Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1) J. Exp. Med. 193 2001 943 954
8. J.E. Durbin, A. Fernandez-Sesma, C.K. Lee, T.D. Rao, A.B. Frey, T.M. Moran, S. Vukmanovic, A. Garcia-Sastre, and D.E. Levy Type I IFN modulates innate and specific antiviral immunity J. Immunol. 164 2000 4220 4228
9. K.A. Fitzgerald, S.M. McWhirter, K.L. Faia, D.C. Rowe, E. Latz, D.T. Golenbock, A.J. Coyle, S.M. Liao, and T. Maniatis IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway Nat. Immunol. 4 2003 491 496
10. K.A. Fitzgerald, D.C. Rowe, B.J. Barnes, D.R. Caffrey, A. Visintin, E. Latz, B. Monks, P.M. Pitha, and D.T. Golenbock LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF J. Exp. Med. 198 2003 1043 1055
11. M. Fotin-Mleczek, F. Henkler, D. Samel, M. Reichwein, A. Hausser, I. Parmryd, P. Scheurich, J.A. Schmid, and H. Wajant Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8 J. Cell Sci. 115 2002 2757 2770
12. K.J. Han, X. Su, L.G. Xu, L.H. Bin, J. Zhang, and H.B. Shu Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways J. Biol. Chem. 279 2004 15652 15661
13. H. Hemmi, O. Takeuchi, S. Sato, M. Yamamoto, T. Kaisho, H. Sanjo, T. Kawai, K. Hoshino, K. Takeda, and S. Akira The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection J. Exp. Med. 199 2004 1641 1650
14. K. Hoebe, X. Du, P. Georgel, E. Janssen, K. Tabeta, S.O. Kim, J. Goode, P. Lin, N. Mann, and S. Mudd Identification of Lps2 as a key transducer of MyD88-independent TIR signalling Nature 424 2003 743 748
15. K. Honda, S. Sakaguchi, C. Nakajima, A. Watanabe, H. Yanai, M. Matsumoto, T. Ohteki, T. Kaisho, A. Takaoka, and S. Akira Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection Proc. Natl. Acad. Sci. USA 100 2003 10872 10877
16. K. Honda, Y. Ohba, H. Yanai, H. Negishi, T. Mizutani, A. Takaoka, C. Taya, and T. Taniguchi Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction Nature 434 2005 1035 1040
17. K. Honda, H. Yanai, H. Negishi, M. Asagiri, M. Sato, T. Mizutani, N. Shimada, Y. Ohba, A. Takaoka, N. Yoshida, and T. Taniguchi IRF-7 is the master regulator of type-I interferon-dependent immune responses Nature 434 2005 772 777
18. Z. Jiang, T.W. Mak, G. Sen, and X. Li Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta Proc. Natl. Acad. Sci. USA 101 2004 3533 3538
19. D.E. Levy, and A. Garcia-Sastre The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion Cytokine Growth Factor Rev. 12 2001 143 156
20. D.E. Levy, and I.J. Marie RIGging an antiviral defense - it's in the CARDs Nat. Immunol. 5 2004 699 701
21. R. Lin, Y. Mamane, and J. Hiscott Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains Mol. Cell. Biol. 19 1999 2465 2474
22. T. Maniatis, J.V. Falvo, T.H. Kim, T.K. Kim, C.H. Lin, B.S. Parekh, and M.G. Wathelet Structure and function of the interferon-beta enhanceosome Cold Spring Harb. Symp. Quant. Biol. 63 1998 609 620
23. A. Matsuda, Y. Suzuki, G. Honda, S. Muramatsu, O. Matsuzaki, Y. Nagano, T. Doi, K. Shimotohno, T. Harada, and E. Nishida Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways Oncogene 22 2003 3307 3318
24. S.M. McWhirter, K.A. Fitzgerald, J. Rosains, D.C. Rowe, D.T. Golenbock, and T. Maniatis IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts Proc. Natl. Acad. Sci. USA 101 2003 233 238
25. H. Oshiumi, M. Matsumoto, K. Funami, T. Akazawa, and T. Seya TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction Nat. Immunol. 4 2003 161 167
26. H. Oshiumi, M. Sasai, K. Shida, T. Fujita, M. Matsumoto, and T. Seya TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta J. Biol. Chem. 278 2003 49751 49762
27. A.K. Perry, E.K. Chow, J.B. Goodnough, W.C. Yeh, and G. Cheng Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection J. Exp. Med. 199 2004 1651 1658
28. S. Sato, M. Sugiyama, M. Yamamoto, Y. Watanabe, T. Kawai, K. Takeda, and S. Akira Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling J. Immunol. 171 2003 4304 4310
29. M.J. Servant, B. Tenoever, and R. Lin Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function J. Interferon Cytokine Res. 22 2002 49 58
30. S. Sharma, B.R. tenOever, N. Grandvaux, G.P. Zhou, R. Lin, and J. Hiscott Triggering the interferon antiviral response through an IKK-related pathway Science 300 2003 1148 1151
31. H.B. Shu, M. Takeuchi, and D.V. Goeddel The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex Proc. Natl. Acad. Sci. USA 93 1996 13973 13978
32. B.R. tenOever, M.J. Servant, N. Grandvaux, R. Lin, and J. Hiscott Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation J. Virol. 76 2002 3659 3669
33. B.R. tenOever, S. Sharma, W. Zou, Q. Sun, N. Grandvaux, I. Julkunen, H. Hemmi, M. Yamamoto, S. Akira, and W.C. Yeh Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity J. Virol. 78 2004 10636 10649
34. H. Wajant, F. Henkler, and P. Scheurich The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators Cell. Signal. 13 2001 389 400
35. M.G. Wathelet, C.H. Lin, B.S. Parekh, L.V. Ronco, P.M. Howley, and T. Maniatis Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo Mol. Cell 1 1998 507 518
36. B.K. Weaver, K.P. Kumar, and N.C. Reich Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1 Mol. Cell. Biol. 18 1998 1359 1368
37. M. Wu, L.G. Xu, Z. Zhai, and H.B. Shu SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription J. Biol. Chem. 278 2003 27072 27079
38. M. Yamamoto, S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling J. Immunol. 169 2002 6668 6672
39. M. Yamamoto, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway Science 301 2003 640 643
40. H. Ye, J.R. Arron, B. Lamothe, M. Cirilli, T. Kobayashi, N.K. Shevde, D. Segal, O.K. Dzivenu, M. Vologodskaia, and M. Yim Distinct molecular mechanism for initiating TRAF6 signalling Nature 418 2002 443 447
41. M. Yoneyama, W. Suhara, Y. Fukuhara, M. Fukuda, E. Nishida, and T. Fujita Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300 EMBO J. 17 1998 1087 1095
42. M. Yoneyama, M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, and T. Fujita The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses Nat. Immunol. 5 2004 730 737
43. L. Zhang, and J.S. Pagano Structure and function of IRF-7 J. Interferon Cytokine Res. 22 2002 95 101