Heterotypic interactions among NACHT domains: Implications for regulation of innate immune responses

Biochemical Journal

Volumn 381, Issue 1, 2004, Pages 213-219

  Damiano, Jason S ^a   Oliveira, Vasco ^a   Welsh, Kate ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Caspase 1; CLAN; Interleukin 1 ; Nod1; Nod2; Nuclear factor B (NF B)

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL ORGANS; CELLS; ENZYMES; PATHOLOGY;

HETEROTYPIC INTERACTIONS; KIDNEY; PATHOGENS;

IMMUNOLOGY;

CASPASE RECRUITMENT DOMAIN PROTEIN 15; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INCOMPATIBILITY LOCUS PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; ISOPROTEIN; LEUCINE; MHC CLASS II TRANSCRIPTION ACTIVATOR; NEURONAL APOPTOSIS INHIBITORY PROTEIN; PROTEIN; PROTEIN ASC; PROTEIN NAC; PROTEIN NOD1; PROTEIN PAN2; TELOMERASE ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPRECIPITATION; IMMUNOREGULATION; ISOMERIZATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN DOMAIN CLAN; PROTEIN DOMAIN NACHT; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CARD SIGNALING ADAPTOR PROTEINS; CARRIER PROTEINS; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; IMMUNITY, NATURAL; INTERLEUKIN-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MONOCYTES; NERVE TISSUE PROTEINS; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; NUCLEOSIDE-PHOSPHATE KINASE; PEPTIDES; PEPTIDOGLYCAN; PROTEIN ISOFORMS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2;

BACTERIA (MICROORGANISMS); PODOSPORA ANSERINA;

EID: 3142674847     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031506     Document Type: Article

References (28)

1. Armant, M. A. and Fenton, M. J. (2002) Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol. 3, REVIEWS3011
2. Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H. et al. (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature (London) 411, 603-606
3. Miceli-Richard, C., Lesage, S., Rybojad, M., Prieur, A. M., Manouvrier-Hanu, S., Hafner, R., Chamaillard, M., Zouali, H., Thomas, G. and Hugot, J. P. (2001) CARD15 mutations in Blau syndrome. Nat. Genet. 29, 19-20
4. Hoffman, H. M., Mueller, J. L., Broide, D. H., Wanderer, A. A. and Kolodner, R. D. (2001) Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29, 301-305
5. Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J. et al. (1995) Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80, 401-411
6. Karin, M. and Delhase, M. (2000) The |κB kinase (IKK) and NF-κB: key elements of proinflammatory signalling. Semin. Immunol. 12, 85-98
7. Jaroszewski, L., Rychlewski, L., Reed, J. C. and Godzik, A. (2000) ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4. Proteins 39, 197-203
8. Koonin, E. V. and Aravind, L. (2000) The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem. Sci. 25, 223-224
9. Linhoff, M. W., Harton, J. A., Cressman, D. E., Martin, B. K. and Ting, J. P. (2001) Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains. Mol. Cell. Biol. 21, 3001-3011
10. Ogura, Y., Inohara, N., Benito, A., Chen, F. F., Yamaoka, S. and Nunez, G. (2001) Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB. J. Biol. Chem. 276, 4812-4818
11. Inohara, N., Koseki, T., Lin, J., del Peso, L., Lucas, P. C., Chen, F. F., Ogura, Y. and Nunez, G. (2000) An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 275, 27823-27831
12. Yoo, N. J., Park, W. S., Kim, S. Y., Reed, J. C., Son, S. G., Lee, J. Y. and Lee, S. H. (2002) Nod1, a CARD protein, enhances pro-interleukin-1β processing through the interaction with pro-caspase-1. Biochem. Biophys. Res. Commun. 299, 652-658
13. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. and Alnemri, E. S. (1998) Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell 1, 949-957
14. Inohara, N., Ogura, Y., Chen, F. F., Muto, A. and Nunez, G. (2001) Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J. Biol. Chem. 276, 2551-2554
15. Girardin, S. E., Boneca, I. G., Viala, J., Chamaillard, M., Labigne, A., Thomas, G., Philpott, D. J. and Sansonetti, P. J. (2003) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278, 8869-8872
16. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S., Hashimoto, M. et al. (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2: implications for Crohn's disease. J. Biol. Chem. 278, 5509-5512
17. Girardin, S. E., Boneca, I. G., Carneiro, L. A., Antignac, A., Jehanno, M., Viala, J., Tedin, K., Taha, M. K., Labigne, A., Zathringer, U. et al. (2003) Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan. Science 300, 1584-1587
18. Chamailiard, M., Hashimoto, M., Horie, Y., Masumoto, J., Qiu, S., Saab, L., Ogura, Y., Kawasaki, A., Fukase, K., Kusumoto, S. et al. (2003) An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat. Immunol. 4, 702-707
19. Damiano, J. S., Stehlik, C., Pio, F., Godzik, A. and Reed, J. C. (2001) CLAN, a novel human CED-4-like gene. Genomics 75, 77-83
20. Poyet, J. L., Srinivasula, S. M., Tnani, M., Razmara, M., Fernandes-Alnemri, T. and Alnemri, E. S. (2001) Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J. Biol. Chem. 276, 28309-28313
21. Reed, J. C., Doctor, K., Rojas, A., Zapata, J. M., Stehlik, C., Fiorentino, L., Damiano, J., Roth, W., Matsuzawa, S., Newman, R. et al. (2003) Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 13, 1376-1388
22. Chu, Z. L., Pio, F., Xie, Z., Welsh, K., Krajewska, M., Krajewski, S., Godzik, A. and Reed, J. C. (2001) A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol Chem. 276, 9239-9245
23. Fiorentino, L., Stehlik, C., Oliveira, V., Ariza, M. E., Godzik, A. and Reed, J. C. (2002) A novel PAAD-containing protein that modulates NF-κB induction by cytokines tumor necrosis factor-α and interleukin-1β. J. Biol. Chem. 277, 35333-35340
24. Inohara, N., Koseki, T., del Peso, L., Hu, Y., Yee, C., Chen, S., Carrio, R., Merino, J., Liu, D., Ni, J. and Nunez, G. (1999) Nod1 an Apaf-1-like activator of caspase-9 and nuclear factor-κB. J. Biol. Chem. 274, 14560-14567
25. Hisamatsu, T., Suzuki, M., Reinecker, H. C., Nadeau, W. J., McCormick, B. A. and Podolsky, D. K. (2003) CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 124, 993-1000
26. Martinon, F., Burns, K. and Tschopp, J. (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 10, 417-426
27. Hu, Y., Ding, L., Spencer, D. M. and Nunez, G. (1998) WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J. Biol. Chem. 273, 33489-33494
28. Srinivasula, S. M., Poyet, J. L., Razmara, M., Datta, P., Zhang, Z. and Alnemri, E. S. (2002) The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J. Biol. Chem. 277, 21119-21122