Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

Journal of Experimental Medicine

Volumn 201, Issue 6, 2005, Pages 915-923

  Uematsu, Satoshi ^a   Sato, Shintaro ^b   Yamamoto, Masahiro ^a   Hirotani, Tomonori ^a   Kato, Hiroki ^a   Takeshita, Fumihiko ^c   Matsuda, Michiyuki ^a   Coban, Cevayir ^d   Ishii, Ken J ^b   Kawai, Taro ^b   Takeuchi, Osamu ^a,b   Akira, Shizuo ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYAN FLUORESCENT PROTEIN; FLT3 LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 12; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; NUCLEAR PROTEIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; YELLOW FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNE DISEASE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EMBRYO; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; INNATE IMMUNITY; INTERFERON PRODUCTION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PLASMA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELL LINE; DENDRITIC CELLS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PLASMA CELLS; PROTEIN KINASES; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9;

EID: 20244388983     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20042372     Document Type: Article

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