ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: The DSB connection

Immunological Reviews

Volumn 209, Issue , 2006, Pages 142-158

  Matei, Irina R ^a,b   Guidos, Cynthia J ^a,b   Danska, Jayne S ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CELL DNA; CYCLOPHOSPHAMIDE; DOUBLE STRANDED DNA; GLUCOCORTICOID; LYMPHOCYTE ANTIGEN RECEPTOR; NIBRIN; OKT 4; OKT 8; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR;

ACUTE LYMPHOCYTIC LEUKEMIA; ALLOGENIC BONE MARROW TRANSPLANTATION; ATAXIA TELANGIECTASIA; AUTOSOMAL RECESSIVE DISORDER; B LYMPHOCYTE; BLOOM SYNDROME; BONE MARROW TRANSPLANTATION; CANCER RISK; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL MATURATION; CELL PROTECTION; CELLULAR IMMUNITY; CEREBELLUM DEGENERATION; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; COMBINED IMMUNODEFICIENCY; COMPARATIVE STUDY; CORTICOSTEROID THERAPY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; EXPERIMENTAL MOUSE; FANCONI ANEMIA; GENE MUTATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION; GENETIC RECOMBINATION; GENOMIC INSTABILITY; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL; HOMOLOGOUS RECOMBINATION; HUMAN; HUMORAL IMMUNITY; IMMUNE DEFICIENCY; IMMUNE SYSTEM; IMMUNOPATHOLOGY; LEUKEMOGENESIS; LEUKOPOIESIS; LYMPHADENOPATHY; LYMPHOCYTOPOIESIS; LYMPHOMA; MAMMAL CELL; MENTAL DEFICIENCY; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; OMENN SYNDROME; OXIDATIVE STRESS; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROLYMPHOCYTIC LEUKEMIA; PROTEIN FUNCTION; RADIOSENSITIVITY; RECEPTOR GENE; REVIEW; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; T CELL LYMPHOMA; T LYMPHOCYTE; TELOMERE; TREATMENT INDICATION; TUMOR SUPPRESSOR GENE;

ANIMALS; ATAXIA TELANGIECTASIA; CELL CYCLE PROTEINS; DNA; DNA DAMAGE; DNA-BINDING PROTEINS; GENE REARRANGEMENT, T-LYMPHOCYTE; GENOMIC INSTABILITY; HUMANS; IMMUNE SYSTEM DISEASES; LEUKEMIA, T-CELL; LYMPHOMA, T-CELL; LYMPHOPOIESIS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEINS; VDJ RECOMBINASES;

EID: 33645072212     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2006.00361.x     Document Type: Review

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