메뉴 건너뛰기




Volumn 184, Issue 2, 1996, Pages 419-428

Transient restoration of gene rearrangement at multiple T cell receptor loci in γ-irradiated scid mice

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; T LYMPHOCYTE RECEPTOR;

EID: 0029788298     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.2.419     Document Type: Article
Times cited : (19)

References (45)
  • 2
    • 0029556045 scopus 로고
    • Receptors and signals in early thymic selection
    • Levelt, C.N., and K. Eichmann. 1995. Receptors and signals in early thymic selection. Immunity. 3:667-672.
    • (1995) Immunity , vol.3 , pp. 667-672
    • Levelt, C.N.1    Eichmann, K.2
  • 3
    • 0029311234 scopus 로고
    • Alpha-beta and gamma-delta T cells can share a late common precursor
    • Dudley, E.C., M. Girardi, M.J. Owen, and A.C. Hayday. 1995. Alpha-beta and gamma-delta T cells can share a late common precursor. Curr. Biol. 5:659-669.
    • (1995) Curr. Biol. , vol.5 , pp. 659-669
    • Dudley, E.C.1    Girardi, M.2    Owen, M.J.3    Hayday, A.C.4
  • 4
    • 0029054748 scopus 로고
    • In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision
    • Livak, F., H.T. Petrie, I.N. Crispe, and D.G. Schatz. 1995. In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision. Immunity. 2:617-627.
    • (1995) Immunity , vol.2 , pp. 617-627
    • Livak, F.1    Petrie, H.T.2    Crispe, I.N.3    Schatz, D.G.4
  • 5
    • 0020663062 scopus 로고
    • A severe combined immunodeficiency mutation in the mouse
    • Bosma, G.C., R.P. Custer, and M.J. Bosma. 1983. A severe combined immunodeficiency mutation in the mouse. Nature (Lond). 301:527-530.
    • (1983) Nature (Lond) , vol.301 , pp. 527-530
    • Bosma, G.C.1    Custer, R.P.2    Bosma, M.J.3
  • 6
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene (RAG-1)
    • Schatz, D.G., M.A. Oettinger, and D. Baltimore. 1989. The V(D)J recombination activating gene (RAG-1). Cell. 59: 1035-1048.
    • (1989) Cell , vol.59 , pp. 1035-1048
    • Schatz, D.G.1    Oettinger, M.A.2    Baltimore, D.3
  • 7
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M.A., D.G. Schatz, C. Gorka, and D. Baltimore. 1990. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science (Wash. DC). 248:1517-1523.
    • (1990) Science (Wash. DC) , vol.248 , pp. 1517-1523
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 10
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., A. Constantinescu, T. Morrow, M. Baxter, and A. Peng. 1993. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes & Dev. 7:2520-2532.
    • (1993) Genes & Dev. , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 12
    • 0026792892 scopus 로고
    • V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • Roth, D.B., J.P. Menetski, P.B. Nakajima, M.J. Bosma, and M. Gellert. 1992. V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell. 70:983-991.
    • (1992) Cell , vol.70 , pp. 983-991
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.B.3    Bosma, M.J.4    Gellert, M.5
  • 14
    • 0024791338 scopus 로고
    • Junctional sequences of T cell receptor gamma delta genes: Implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining
    • Lafaille, J.J., A. DeCloux, M. Bonneville, Y. Takagaki, and S. Tonegawa. 1989. Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining. Cell. 59:859-70.
    • (1989) Cell , vol.59 , pp. 859-870
    • Lafaille, J.J.1    DeCloux, A.2    Bonneville, M.3    Takagaki, Y.4    Tonegawa, S.5
  • 15
    • 0026331952 scopus 로고
    • T-cell receptor γ and δ rearrangements in scid thymocytes: Similarity to those in normal thymocytes
    • Kienker, L.J., W.A. Kuziel, B.A. Garni-Wagner, and V. Kumar. 1991. T-cell receptor γ and δ rearrangements in scid thymocytes: similarity to those in normal thymocytes. J. Immunol. 147:4351-4359.
    • (1991) J. Immunol. , vol.147 , pp. 4351-4359
    • Kienker, L.J.1    Kuziel, W.A.2    Garni-Wagner, B.A.3    Kumar, V.4
  • 16
    • 0025938549 scopus 로고
    • T-cell receptor γ and δ gene junctional sequences in scid mice: Excessive P nucleotide insertion
    • Kienker, L.J., W.A. Kuziel, and P.W. Tucker. 1991. T-cell receptor γ and δ gene junctional sequences in scid mice: excessive P nucleotide insertion. J. Exp. Med. 174:769-775.
    • (1991) J. Exp. Med. , vol.174 , pp. 769-775
    • Kienker, L.J.1    Kuziel, W.A.2    Tucker, P.W.3
  • 17
    • 0026087635 scopus 로고
    • Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: Unusual P-nucleotide additions in VJ-coding joints
    • Schuler, W., N.R. Ruetsch, M. Amsler, and M.J. Bosma. 1991. Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P-nucleotide additions in VJ-coding joints. Eur. J. Immunol. 21:589-596.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 589-596
    • Schuler, W.1    Ruetsch, N.R.2    Amsler, M.3    Bosma, M.J.4
  • 20
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb, T.M., and S.P. Jackson. 1993. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell. 72:131-142.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 25
    • 0030069149 scopus 로고    scopus 로고
    • T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells
    • Livak, F., and D.G. Schatz. 1996. T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells. Mol. Cell. Biol. 16:609-618.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 609-618
    • Livak, F.1    Schatz, D.G.2
  • 26
    • 0024536439 scopus 로고
    • T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression
    • Takagaki, Y., N. Nakanishi, I. Ishida, O. Kanagawa, and S. Tonegawa. 1989. T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression. J. Immunol. 142:2112-2121.
    • (1989) J. Immunol. , vol.142 , pp. 2112-2121
    • Takagaki, Y.1    Nakanishi, N.2    Ishida, I.3    Kanagawa, O.4    Tonegawa, S.5
  • 28
    • 0026018228 scopus 로고
    • T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor δ gene recombination
    • Caroll, A.M., and M.J. Bosma. 1991. T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor δ gene recombination. Genes & Dev. 5:1357-1366.
    • (1991) Genes & Dev. , vol.5 , pp. 1357-1366
    • Caroll, A.M.1    Bosma, M.J.2
  • 29
    • 0028467163 scopus 로고
    • An activated lck transgene promotes thymocyte development in RAG-1 mutant mice
    • Mombaerts, P., S.J. Anderson, R.M. Perlmutter, T.W. Mak, and S. Tonegawa. 1994. An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. Immunity. 1:261-267.
    • (1994) Immunity , vol.1 , pp. 261-267
    • Mombaerts, P.1    Anderson, S.J.2    Perlmutter, R.M.3    Mak, T.W.4    Tonegawa, S.5
  • 30
    • 0027474344 scopus 로고
    • T cell receptor δ gene mutant mice independent generation of αβ T cells and programmed rearrangements of γδ TCR genes
    • Itohara, S., P. Mombaerts, J. Lafaille, J. Iacomini, A. Nelson, A.R. Clarke, M.L. Hooper, A. Farr, and S. Tonegawa. 1993. T cell receptor δ gene mutant mice independent generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell. 72:337-348.
    • (1993) Cell , vol.72 , pp. 337-348
    • Itohara, S.1    Mombaerts, P.2    Lafaille, J.3    Iacomini, J.4    Nelson, A.5    Clarke, A.R.6    Hooper, M.L.7    Farr, A.8    Tonegawa, S.9
  • 31
    • 0029024913 scopus 로고
    • T cell receptor gene recombination patterns and mechanisms: Cell death, rescue and T cell production
    • Petrie, H.T., F. Livak, D. Burtrum, and S. Mazel. 1995. T cell receptor gene recombination patterns and mechanisms: cell death, rescue and T cell production. J. Exp. Med 182: 121-127.
    • (1995) J. Exp. Med , vol.182 , pp. 121-127
    • Petrie, H.T.1    Livak, F.2    Burtrum, D.3    Mazel, S.4
  • 32
    • 0028426281 scopus 로고
    • T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice
    • Dudley, E.C., H.T. Petrie, L.M. Shah, M.J. Owen, and A.C. Hayday. 1994. T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice. Immunity. 1:83-93.
    • (1994) Immunity , vol.1 , pp. 83-93
    • Dudley, E.C.1    Petrie, H.T.2    Shah, L.M.3    Owen, M.J.4    Hayday, A.C.5
  • 33
    • 0026706487 scopus 로고
    • Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region
    • Koop, B.F., R.K. Wilson, K. Wang, B. Vernooij, D. Zallwer, C. Kuo, D. Seto, M. Toda, and L. Hood. 1992. Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region. Genomics. 13: 1209-1230.
    • (1992) Genomics , vol.13 , pp. 1209-1230
    • Koop, B.F.1    Wilson, R.K.2    Wang, K.3    Vernooij, B.4    Zallwer, D.5    Kuo, C.6    Seto, D.7    Toda, M.8    Hood, L.9
  • 34
    • 0023801238 scopus 로고
    • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
    • Lieber, M.R., J.E. Hesse, S. Lewis, G.C. Bosma, N. Rosenberg, K. Mizuuchi, M.J. Bosma, and M. Gellert. 1988. The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell. 55:7-16.
    • (1988) Cell , vol.55 , pp. 7-16
    • Lieber, M.R.1    Hesse, J.E.2    Lewis, S.3    Bosma, G.C.4    Rosenberg, N.5    Mizuuchi, K.6    Bosma, M.J.7    Gellert, M.8
  • 35
    • 0028958942 scopus 로고
    • Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination
    • Zhu, C., and D.B. Roth. 1995. Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination. Immunity. 2:101-112.
    • (1995) Immunity , vol.2 , pp. 101-112
    • Zhu, C.1    Roth, D.B.2
  • 36
    • 0028805853 scopus 로고
    • Cleavage at a V(D)J recombination signal requires only rag-1 and rag-2 proteins and occurs in two steps
    • McBlane, J.F., D.C. v. Gent, D.A. Ramsen, G. Romeo, G.A. Cuomo, M. Gellert, and M.A. Oettinger. 1995. Cleavage at a V(D)J recombination signal requires only rag-1 and rag-2 proteins and occurs in two steps. Cell. 83:387-396.
    • (1995) Cell , vol.83 , pp. 387-396
    • McBlane, J.F.1    V Gent, D.C.2    Ramsen, D.A.3    Romeo, G.4    Cuomo, G.A.5    Gellert, M.6    Oettinger, M.A.7
  • 38
    • 0028897304 scopus 로고
    • DNA-dependent protein kinase activity is absent in xrs-6 cells - Implications for site-specific recombination and DNA double-strand break repair
    • Finnie, N.J., T.M. Gottlieb, T. Blunt, P.A. Jeggo, and S.P. Jackson. 1995. DNA-dependent protein kinase activity is absent in xrs-6 cells - implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA. 92:320-324.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 40
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNA repair
    • Fulop, G.M., and R.A. Phillips. 1990. The scid mutation in mice causes a general defect in DNA repair. Nature (Lond.). 347:479-482.
    • (1990) Nature (Lond.) , vol.347 , pp. 479-482
    • Fulop, G.M.1    Phillips, R.A.2
  • 41
    • 0026071588 scopus 로고
    • scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
    • Biedermann, K.A., J.R. Sun, A.J. Giaccia, L.M. Tosto, and J.M. Brown. 1991. scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA. 88:1394-1397.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1394-1397
    • Biedermann, K.A.1    Sun, J.R.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, J.M.5
  • 42
    • 0028283180 scopus 로고
    • Abnormal deletions in the T-cell receptor 6 locus of mouse thymocytes
    • Fish, S.M., and M.J. Bosma. 1994. Abnormal deletions in the T-cell receptor 6 locus of mouse thymocytes. Mol. Cell. Biol. 14:4455-4464.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4455-4464
    • Fish, S.M.1    Bosma, M.J.2
  • 43
    • 0029302857 scopus 로고
    • Repair and recombination - How to make ends meet
    • Roth, D.B., T. Lindahl, and M. Gellert. 1995. Repair and recombination - how to make ends meet. Curr. Biol. 5:496-499.
    • (1995) Curr. Biol. , vol.5 , pp. 496-499
    • Roth, D.B.1    Lindahl, T.2    Gellert, M.3
  • 44
    • 0025754262 scopus 로고
    • Strands breaks without DNA rearrangement in V(D)J recombination
    • Hendrickson, E.A., V.F. Liu, and D.T. Weaver. 1991. Strands breaks without DNA rearrangement in V(D)J recombination. Mol. Cell. Biol. 11:3155-3162.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3155-3162
    • Hendrickson, E.A.1    Liu, V.F.2    Weaver, D.T.3
  • 45
    • 0028860551 scopus 로고
    • V-D-J rearrangements at the T cell receptor δ locus in mouse thymocytes of the αβ lineage
    • Nakajima, P.B., J.P. Menetski, D.B. Roth, M. Gellert, and M.J. Bosma. 1995. V-D-J rearrangements at the T cell receptor δ locus in mouse thymocytes of the αβ lineage. Immunity. 3:609-622.
    • (1995) Immunity , vol.3 , pp. 609-622
    • Nakajima, P.B.1    Menetski, J.P.2    Roth, D.B.3    Gellert, M.4    Bosma, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.