Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations

Cell

Volumn 109, Issue 7, 2002, Pages 811-821

  Zhu, Chengming ^a   Mills, Kevin D ^a   Ferguson, David O ^a,b   Lee, Charles ^b   Manis, John ^a   Fleming, James ^a   Gao, Yijie ^a   Morton, Cynthia C ^b,d   Alt, Frederick W ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b Department of Pathology ^*  (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B CELL LYMPHOMA; CARCINOGENESIS; CHROMOSOME 12; CHROMOSOME 15; CHROMOSOME TRANSLOCATION 12; CHROMOSOME TRANSLOCATION 15; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DNA REPAIR; DNA STRAND BREAKAGE; GENE AMPLIFICATION; GENE LOCATION; GENE LOCUS; GENE SEQUENCE; GENETIC RECOMBINATION; MOUSE; NEWBORN; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ANIMALIA;

EID: 0037188898     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00770-5     Document Type: Article

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