-
1
-
-
0028822481
-
Chronic lymphocytic leukemia
-
Rozman C, Montserrat E. Chronic lymphocytic leukemia. N Engl J Med. 1995;333:1052-1057.
-
(1995)
N Engl J Med
, vol.333
, pp. 1052-1057
-
-
Rozman, C.1
Montserrat, E.2
-
2
-
-
0032941221
-
B-cell chronic lymphocytic leukemia: A bird of a different feather
-
Caligaris-Capio F, Hamblin TJ. B-cell chronic lymphocytic leukemia: a bird of a different feather. J Clin Oncol. 1999;17:399-408.
-
(1999)
J Clin Oncol
, vol.17
, pp. 399-408
-
-
Caligaris-Capio, F.1
Hamblin, T.J.2
-
3
-
-
0031442979
-
p53 abnormalities in CLL are associated with excess of prolymphocytes and poor prognosis
-
Lens D, Dyer M, Garcia-Marco JM, et al. p53 abnormalities in CLL are associated with excess of prolymphocytes and poor prognosis. Br J Haematol. 1997;99:848-857.
-
(1997)
Br J Haematol
, vol.99
, pp. 848-857
-
-
Lens, D.1
Dyer, M.2
Garcia-Marco, J.M.3
-
4
-
-
0027436745
-
p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
-
El Rouby S, Thomas A, Costin D, et al. p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression. Blood. 1993;82:3452-3459.
-
(1993)
Blood
, vol.82
, pp. 3452-3459
-
-
El Rouby, S.1
Thomas, A.2
Costin, D.3
-
5
-
-
0028172868
-
p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E, Preudhomme C, Hecquet B, et al. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood. 1994;84:3148-3157.
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
-
6
-
-
0028987180
-
p53 gene deletion predicts for poor survival and nonresponse to therapy with purine analogues in chronic B-cell leukaemias
-
Dohner H, Fischer C, Bentz M, et al. p53 gene deletion predicts for poor survival and nonresponse to therapy with purine analogues in chronic B-cell leukaemias. Blood. 1995;85:1580-1589.
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Dohner, H.1
Fischer, C.2
Bentz, M.3
-
7
-
-
0027109075
-
p53, guardian of the genome
-
Lane DP. p53, guardian of the genome. Nature. 1992;358:15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
8
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev. 1996;10:1054-1072.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
9
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 1997;88:323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
10
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig R. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 1991;51:6301-6311.
-
(1991)
Cancer Res
, vol.51
, pp. 6301-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.5
-
11
-
-
0027500246
-
Induction of nuclear accumulation of the tumour suppressor protein p53 by DNA-damaging agents
-
Fritsche M, Haessler C, Brandner G. Induction of nuclear accumulation of the tumour suppressor protein p53 by DNA-damaging agents. Oncogene. 1993;8:307-318.
-
(1993)
Oncogene
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brandner, G.3
-
12
-
-
0027359827
-
WAF1, a potential mediator of p53 tumour suppression
-
El-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumour suppression. Cell. 1993;75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
13
-
-
0028883179
-
Tumour suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed J. Tumour suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 1995;80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.2
-
14
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
Miyashita T, Harigai M, Hanada M, Reed JC. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res. 1994;54:3131-3135.
-
(1994)
Cancer Res
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
15
-
-
0028124528
-
p53 and human cancers
-
Lane DP. p53 and human cancers. Br Med Bull. 1994;50:582-599.
-
(1994)
Br Med Bull
, vol.50
, pp. 582-599
-
-
Lane, D.P.1
-
16
-
-
0028025564
-
How loops, β sheets, and α helices help us to understand p53
-
Prives C. How loops, β sheets, and α helices help us to understand p53. Cell. 1994;78:543-546.
-
(1994)
Cell
, vol.78
, pp. 543-546
-
-
Prives, C.1
-
17
-
-
0028955358
-
p53 gene mutations in lymphoid disease and their possible relevance to drug resistance
-
Newcombe EW. p53 gene mutations in lymphoid disease and their possible relevance to drug resistance. Leuk Lymphoma. 1995;17:211-221.
-
(1995)
Leuk Lymphoma
, vol.17
, pp. 211-221
-
-
Newcombe, E.W.1
-
18
-
-
0026533307
-
Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: A simple and sensitive method
-
Anastasi J, Le Beau MM, Vardiman JW, et al. Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method. Blood. 1992;79:1796-1801.
-
(1992)
Blood
, vol.79
, pp. 1796-1801
-
-
Anastasi, J.1
Le Beau, M.M.2
Vardiman, J.W.3
-
19
-
-
1842328565
-
11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis
-
Dohner H, Stilgenbauer S, James MR, et al. 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood. 1997;89:2516-2522.
-
(1997)
Blood
, vol.89
, pp. 2516-2522
-
-
Dohner, H.1
Stilgenbauer, S.2
James, M.R.3
-
20
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature. 1992;358:80-83.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
21
-
-
0028081261
-
The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin
-
Watanabe T, Hotta T, Kinoshita T, et al. The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin. Blood. 1994;84:3158-3165.
-
(1994)
Blood
, vol.84
, pp. 3158-3165
-
-
Watanabe, T.1
Hotta, T.2
Kinoshita, T.3
-
22
-
-
0028899276
-
Multiple patterns of MDM-2 deregulation in human leukemias: Implications in leukemogenesis and prognosis
-
Bues-Ramos CE, Manshouri T, Haidar MA, Huh YO, Keating MJ, Albitar M. Multiple patterns of MDM-2 deregulation in human leukemias: implications in leukemogenesis and prognosis. Leuk Lymphoma. 1995;17:13-18.
-
(1995)
Leuk Lymphoma
, vol.17
, pp. 13-18
-
-
Bues-Ramos, C.E.1
Manshouri, T.2
Haidar, M.A.3
Huh, Y.O.4
Keating, M.J.5
Albitar, M.6
-
23
-
-
0010732479
-
B-cell chronic lymphocytic leukemia: Association between the MDM2 and p53 protein expression and trisomy 12
-
Hjalmar V, Kimby E, Christensson B. B-cell chronic lymphocytic leukemia: association between the MDM2 and p53 protein expression and trisomy 12 [abstract]. Blood. 1999;94:546.
-
(1999)
Blood
, vol.94
, pp. 546
-
-
Hjalmar, V.1
Kimby, E.2
Christensson, B.3
-
24
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
Prives C. Signaling to p53: breaking the MDM2-p53 circuit. Cell. 1998;95:5-8.
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
25
-
-
0031953837
-
What has the cloning of the ATM gene told us about ataxia telangiectasia?
-
Taylor AMR. What has the cloning of the ATM gene told us about ataxia telangiectasia? Int J Radiol Biol. 1998;73:365-371.
-
(1998)
Int J Radiol Biol
, vol.73
, pp. 365-371
-
-
Taylor, A.M.R.1
-
26
-
-
0000303499
-
ATM associates with and phosphorylates p53: Mapping the region of interaction
-
Khanna KK, Keating KE, Kozlov S, et al. ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet. 1998;20:398-400.
-
(1998)
Nat Genet
, vol.20
, pp. 398-400
-
-
Khanna, K.K.1
Keating, K.E.2
Kozlov, S.3
-
27
-
-
0031840253
-
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
-
Waterman MJF, Stravridi ES, Waterman JLF, Halazonetis TD. ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. Nat Genet. 1998;19:175-178.
-
(1998)
Nat Genet
, vol.19
, pp. 175-178
-
-
Waterman, M.J.F.1
Stravridi, E.S.2
Waterman, J.L.F.3
Halazonetis, T.D.4
-
28
-
-
0032532095
-
Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia
-
Starostik P, Manshouri T, O'Brien S, et al. Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia. Cancer Res. 1998;58:4552-4557.
-
(1998)
Cancer Res
, vol.58
, pp. 4552-4557
-
-
Starostik, P.1
Manshouri, T.2
O'Brien, S.3
-
29
-
-
0033513587
-
Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia
-
Stankovic T, Weber P, Stewart G, et al. Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia. Lancet. 1999;353:26-29.
-
(1999)
Lancet
, vol.353
, pp. 26-29
-
-
Stankovic, T.1
Weber, P.2
Stewart, G.3
-
30
-
-
0033566329
-
Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia
-
Schaffner C, Stilgenbauer S, Rappold GA, Dohner H, Lichter P. Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia. Blood. 1999;94:748-753.
-
(1999)
Blood
, vol.94
, pp. 748-753
-
-
Schaffner, C.1
Stilgenbauer, S.2
Rappold, G.A.3
Dohner, H.4
Lichter, P.5
-
31
-
-
0032944319
-
ATM mutations in B-cell chronic lymphocytic leukemia
-
Bullrich F, Rasio D, Kitada S, et al. ATM mutations in B-cell chronic lymphocytic leukemia. Cancer Res. 1999;59:24-27.
-
(1999)
Cancer Res
, vol.59
, pp. 24-27
-
-
Bullrich, F.1
Rasio, D.2
Kitada, S.3
-
32
-
-
0030667522
-
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
-
Barlow C, Brown KD, Deng C-X, et al. Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat Genet. 1997;17:453-456.
-
(1997)
Nat Genet
, vol.17
, pp. 453-456
-
-
Barlow, C.1
Brown, K.D.2
Deng, C.-X.3
-
33
-
-
0030879563
-
Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity
-
Westphal CH, Rowan S, Schmaltz C, Elson A, Fisher DE, Leder P. Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity. Nat Genet. 1997;16:397-401.
-
(1997)
Nat Genet
, vol.16
, pp. 397-401
-
-
Westphal, C.H.1
Rowan, S.2
Schmaltz, C.3
Elson, A.4
Fisher, D.E.5
Leder, P.6
-
34
-
-
0027486024
-
Ionising radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells
-
Khanna KK, Lavin MF. Ionising radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. Oncogene. 1993;8:3307-3312.
-
(1993)
Oncogene
, vol.8
, pp. 3307-3312
-
-
Khanna, K.K.1
Lavin, M.F.2
-
35
-
-
0032931517
-
The p53 pathway
-
Prives C, Hall PA. The p53 pathway. J Pathol. 1999;187:112-126.
-
(1999)
J Pathol
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
36
-
-
0029051336
-
Coupling between gamma irradiation, p53 induction and the apoptotic response depends on cell type in vivo
-
Midgeley CA, Owens B, Briscoe CV, Thomas DB, Lane DP, Hall PA. Coupling between gamma irradiation, p53 induction and the apoptotic response depends on cell type in vivo. J Cell Sci. 1995;108:1943-1848.
-
(1995)
J Cell Sci
, vol.108
, pp. 1943-1848
-
-
Midgeley, C.A.1
Owens, B.2
Briscoe, C.V.3
Thomas, D.B.4
Lane, D.P.5
Hall, P.A.6
-
37
-
-
0018140371
-
Role of cell shape in growth control
-
Folkman J, Moscona A. Role of cell shape in growth control. Nature. 1978;273:345-349.
-
(1978)
Nature
, vol.273
, pp. 345-349
-
-
Folkman, J.1
Moscona, A.2
-
38
-
-
0027298576
-
Induction of cellular p53 activity by DNA-damaging agents and growth arrest
-
Zhan Q, Carrier F, Fornace JR. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol. 1993;13:4242-4250.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4242-4250
-
-
Zhan, Q.1
Carrier, F.2
Fornace, J.R.3
-
39
-
-
0025743732
-
"Touchdown" PCR to circumvent spurious priming during gene amplification
-
Don RH, Cox PT, Wainwright BJ, Baker K, Mattick JS. "Touchdown" PCR to circumvent spurious priming during gene amplification [abstract]. Nucleic Acids Res. 1991;19:4008.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 4008
-
-
Don, R.H.1
Cox, P.T.2
Wainwright, B.J.3
Baker, K.4
Mattick, J.S.5
-
40
-
-
0034176112
-
Granulocyte-macrophage colony-stimulating factor as an autocrine survival factor for mature normal and malignant B lymphocytes
-
Harris RJ, Pettitt AR, Schmutz C, et al. Granulocyte-macrophage colony-stimulating factor as an autocrine survival factor for mature normal and malignant B lymphocytes. J Immunol. 2000;164:3887-3893.
-
(2000)
J Immunol
, vol.164
, pp. 3887-3893
-
-
Harris, R.J.1
Pettitt, A.R.2
Schmutz, C.3
-
41
-
-
0028800690
-
Restriction endonuclease fingerprinting (REF): A sensitive method for screening in long contiguous segments of DNA
-
Liu Q, Sommer SS. Restriction endonuclease fingerprinting (REF): a sensitive method for screening in long contiguous segments of DNA. Biol Tech. 1995;18:470-477.
-
(1995)
Biol Tech
, vol.18
, pp. 470-477
-
-
Liu, Q.1
Sommer, S.S.2
-
42
-
-
9344219890
-
The ATM gene and susceptibility to breast cancer: Analysis of 38 breast tumors reveals no evidence for mutation
-
Vorechovsky I, Rasio D, Luo L, et al. The ATM gene and susceptibility to breast cancer: analysis of 38 breast tumors reveals no evidence for mutation. Cancer Res. 1996;56:2726-2732.
-
(1996)
Cancer Res
, vol.56
, pp. 2726-2732
-
-
Vorechovsky, I.1
Rasio, D.2
Luo, L.3
-
43
-
-
0031825118
-
The study of apoptotic cells by flow cytometry
-
Ormerod MG. The study of apoptotic cells by flow cytometry. Leukemia. 1998;12:1013-1025.
-
(1998)
Leukemia
, vol.12
, pp. 1013-1025
-
-
Ormerod, M.G.1
-
44
-
-
0026584181
-
Induction of apoptosis in chronic lymphocytic leukemia cells and its prevenetion by phorbol ester
-
Forbes IJ, Zalewski PD, Giannakis C, Cowled PA. Induction of apoptosis in chronic lymphocytic leukemia cells and its prevenetion by phorbol ester. Exp Cell Res. 1992;198:367-372.
-
(1992)
Exp Cell Res
, vol.198
, pp. 367-372
-
-
Forbes, I.J.1
Zalewski, P.D.2
Giannakis, C.3
Cowled, P.A.4
-
45
-
-
0019929362
-
Hormone-induced cell death: Purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment
-
Wyllie AH, Morris RG. Hormone-induced cell death: purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment. Am J Pathol. 1982;109:78-87.
-
(1982)
Am J Pathol
, vol.109
, pp. 78-87
-
-
Wyllie, A.H.1
Morris, R.G.2
-
46
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 1993;53:3976-3985.
-
(1993)
Cancer Res
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
47
-
-
0031890032
-
Molecular biology of chronic lymphocytic leukaemia
-
Reed JC. Molecular biology of chronic lymphocytic leukaemia. Semin Oncol. 1998;25:11-18.
-
(1998)
Semin Oncol
, vol.25
, pp. 11-18
-
-
Reed, J.C.1
-
48
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 1993;362:847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
49
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 1993;362:849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
-
50
-
-
0026669469
-
p53 function and dysfunction
-
Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell. 1992;70:523-526.
-
(1992)
Cell
, vol.70
, pp. 523-526
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
51
-
-
0034707047
-
The DNA damage response: Putting checkpoints in prospective
-
Zhou B-BS, Elledge SJ. The DNA damage response: putting checkpoints in prospective. Nature. 2000;408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.-B.S.1
Elledge, S.J.2
-
52
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxiclty of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, et al. p53-dependent apoptosis modulates the cytotoxiclty of anticancer agents. Cell. 1993;74:957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
-
53
-
-
0025731379
-
Cotranslation of activated mutant p53 with wild-type drives the wild-type p53 protein into the mutant conformation
-
Milner J, Metcalf EA. Cotranslation of activated mutant p53 with wild-type drives the wild-type p53 protein into the mutant conformation. Cell. 1991;65:765-774.
-
(1991)
Cell
, vol.65
, pp. 765-774
-
-
Milner, J.1
Metcalf, E.A.2
|